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  1. Pathogenicity and phylogenetic analysis of ovine contagious ecthyma virus isolated during a sheeppox outbreak in Morocco
    Bamouh Z, Tifrouin I, Elkarhat Z, Abid L, Fellahi S, Elharrak M
    Microb Pathog, 2024 Dec;197:107023.
    PMID: 39423917 DOI: 10.1016/j.micpath.2024.107023
    Contagious ecthyma (CE), also known as ORF is a highly contagious zoonotic viral skin disease that affects humans, sheep, goats and other domesticated and wild animals. As reported here-in, the objective of this study was to investigate a suspected outbreak of both sheeppox and ORF diseases in a sheep herd during the winter of 2020 in Northwest Morocco. The affected sheep showed nodules and proliferative scabby skin lesions around the mouth and hairless area of the body. Samples of skin crust were collected for virus identification and isolation. A virus was isolated in Vero cells, lamb testis and heart cells and the cytopathic effect was characterized by cells aggregation, ballooning, and detachment. Initially, the suspensions of skin crust were positive for sheeppox virus (SPPV) by PCR. Subsequent testing of the isolated virus from skin crust of affected animals indicated that the virus was SPPV-negative and ORFV-positive by PCR. Furthermore, nucleotide sequences of the B2L aligned with reference ORFV isolates for genetic analysis. Phylogenetic analyses results confirmed that the isolated virus was ORFV and that the virus was closely related to ORFV strains isolated in Sudan and Malaysia. In conclusion, this study is the first reported detection of ORFV in Morocco, and therefore, poses as an imminent threat to the health of humans, domestic and wild animals.
    Matched MeSH terms: Morocco/epidemiology
  2. Posidonomya (Bivalvia) from Northwest Peninsular Malaysia and its significance
    Basir Jasin
    Sains Malaysiana, 2015;44:217-223.
    Posidonomya is common in the Kubang Pasu and Singa Formations in northwest Peninsular Malaysia. It was discovered from the red mudstone layers (redbeds) in many localities in Langkawi Islands, Perlis and Kedah. Previous studies suggested that the age of Posidonomya ranged from Middle Devonian to Carboniferous. Posidonomya beds in Kedah and Perlis are located above the Tournaisian radiolarian chert layers. The age of Posidonomya from Peninsular Malaysia is comparable to those of Europe, Morocco, Turkey and South China which range from Tournaisian to Serpukhovian, Early Carboniferous. The fossil specimens exhibit morphological features closely related to Posidonomya becheri Bronn. Two taxa were identified namely Posidonomya becheri Bronn and Posidonomya cf. kochi (von Koenen). The occurrence of Posidonomya indicates that the age of the lower part of the Kubang Pasu and Singa Formations is Early Carboniferous. Its geographic distribution formed a wide paleobiogeographic province in the Paleo-Tethys. The province was located in the warm tropical-subtropical climatic zone. Therefore, Posidonomya can be a good indicator for warm climate. Its wide distribution and short stratigraphic range make it a good index fossil for the Early Carboniferous.
    Matched MeSH terms: Morocco
  3. Fulltext COVID-19 Vaccine Acceptance among Social Media Users: A Content Analysis, Multi-Continent Study
    Shaaban R, Ghazy RM, Elsherif F, Ali N, Yakoub Y, Aly MO, et al.
    Int J Environ Res Public Health, 2022 May 08;19(9).
    PMID: 35565132 DOI: 10.3390/ijerph19095737
    Vaccine hesitancy (VH) is defined as a delayed in acceptance or refusal of vaccines despite availability of vaccination services. This multinational study examined user interaction with social media about COVID-19 vaccination. The study analyzed social media comments in 24 countries from five continents. In total, 5856 responses were analyzed; 83.5% of comments were from Facebook, while 16.5% were from Twitter. In Facebook, the overall vaccine acceptance was 40.3%; the lowest acceptance rates were evident in Jordan (8.5%), Oman (15.0%), Senegal (20.0%) and Morocco (20.7%) and the continental acceptance rate was the lowest in North America 22.6%. In Twitter, the overall acceptance rate was (41.5%); the lowest acceptance rate was found in Oman (14.3%), followed by USA (20.5%), and UK (23.3%) and the continental acceptance rate was the lowest in North America (20.5%), and Europe (29.7%). The differences in vaccine acceptance across countries and continents in Facebook and Twitter were statistically significant. Regarding the tone of the comments, in Facebook, countries that had the highest number of serious tone comments were Sweden (90.9%), USA (61.3%), and Thailand (58.8%). At continent level, serious comments were the highest in Asia (58.4%), followed by Africa (46.2%) and South America (46.2%). In Twitter, the highest serious tone was reported in Egypt (72.2%) while at continental level, the highest proportion of serious comments was observed in Asia (59.7%), followed by Europe (46.5%). The differences in tone across countries and continents in Facebook and Twitter and were statistically significant. There was a significant association between the tone and the position of comments. We concluded that the overall vaccine acceptance in social media was relatively low and varied across the studied countries and continents. Consequently, more in-depth studies are required to address causes of such VH and combat infodemics.
    Matched MeSH terms: Morocco
  4. Hydrogeochemical assessment of aquifer salinization in north-eastern Morocco's Gueroaou coastal plain using statistical methods
    Chahban M, Akodad M, Skalli A, Gueddari H, El Yousfi Y, Ait Hmeid H, et al.
    Environ Res, 2024 Mar 01;244:117939.
    PMID: 38128604 DOI: 10.1016/j.envres.2023.117939
    The Guerouaou aquifer investigation spanning 280 km2 in Ain Zohra yields promising outcomes, instilling optimism for regional water quality. These analyses were applied to 45 sampling instances from 43 wells, enabling a comprehensive water quality assessment. Groundwater conductivity ranged from medium to high, peaking at 18360 ms/cm2. The conductivity reveals insights about the groundwater's mineralization. Key physiochemical parameters fell within desirable thresholds, bolstering the positive perspective. HCO3- levels spanned 82-420 mg/L, while chloride content ranged from 38 to 5316 mg/L, benefiting water quality. NO3- ions, vital for gauging pollution, ranged from 0 to 260 mg/L, indicating favorable results. Cation concentrations exhibited encouraging variations: Ca2+- 24 to 647 mg/L, Mg2+- 12 to 440 mg/L, Na+- 18 to 2722 mg/L, K+- 1.75 to 28.65 mg/L. These collectively favor water quality. Halite breakdown dominated mineralization, as evidenced by the prevalence of Na-Cl-Na-SO4 facies. Water resource management and local communities need effective management and mitigation strategies to prevent saltwater intrusion.
    Matched MeSH terms: Morocco
  5. Aggressive periodontitis with a history of orthodontic treatment
    Gupta VV, Ramachandra SS
    J Indian Soc Periodontol, 2019 8 2;23(4):371-376.
    PMID: 31367137 DOI: 10.4103/jisp.jisp_654_18
    This report presents a 29-year-old aggressive periodontitis patient from Morocco with a history of orthodontic treatment. Despite all the first molars showing advanced bone loss, the maxillary anterior teeth did not show any periodontal destruction. The scientific literature rarely reports cases of aggressive periodontitis without involving maxillary anterior teeth. The treatment provided includes extraction of hopeless tooth, removal of overhanging restoration, scaling, root debridement, and regenerative periodontal therapy. The discussion highlights the dilemma during diagnosis of the case as either "iatrogenic periodontitis due to orthodontic treatment" or "localized aggressive periodontitis." The age group of 15-35 years is the common age group for patients' seeking orthodontic treatment and the occurrence of aggressive periodontitis. Sound knowledge of periodontitis and identification of early signs of aggressive periodontitis through meticulous periodontal examination may help in earlier identification and minimalistic treatment. Education regarding periodontitis, especially aggressive periodontitis, is essential among orthodontists and general dentists. This case report aims to discuss the dilemma involved during diagnosis of localized aggressive periodontitis.
    Matched MeSH terms: Morocco
  6. Fulltext Public preference of Islamic garden elements and professional perceptions towards Astaka Moroco in Putrajaya compared to Middle Eastern Islamic Gardens
    Fazlena Abd. Rahim, Norsidah Ujang, Mohamed Mohamed Tolba Said
    Journal of Advanced Research Design, 2018;46(1):1-13.
    MyJurnal
    The lack of understanding of Islamic principles in the design of public spaces has led to
    the weakness of the function, aesthetic value and the identity of urban places. The study
    seeks to identify the characteristics and elements of the Islamic urban space in
    Putrajaya base on publics and expert perception and preference. A questionnaire
    survey was conducted with approximately 500 civilians to analyse the public perception
    of Putra Square and Astaka Moroco. A photo base interview was carried out with
    approximately 100 professionals in the built environment field to evaluate the quality
    of Astaka Moroco in comparison to Islamic gardens in the Middle East based on their
    perception. The results indicate that the style of the Dataran Putra is the most preferred
    by the public compared to the Astaka Morocco. The professionals inform that Astaka
    Morocco is not comparable to the quality of Islamic gardens in the Middle East either
    in terms of function or aesthetic value due to the lack of understanding of the Islamic gardens elements and principles. In addition, the public liked the Islamic garden style
    that reflects the local identity and the functions as public spaces instead of just as an
    exhibit or a model. The findings can be a good guide in designing the Islamic public
    spaces which are favoured by the public.
    Matched MeSH terms: Morocco
  7. Fulltext Contribution of Arab countries to pharmaceutical wastewater literature: a bibliometric and comparative analysis of research output
    Zyoud SH, Zyoud SH, Al-Jabi SW, Sweileh WM, Awang R
    Ann Occup Environ Med, 2016;28:28.
    PMID: 27382475 DOI: 10.1186/s40557-016-0117-0
    BACKGROUND: Recently, the pharmaceutical manufacturing industry has been growing rapidly in many countries in the world, including in Arab countries. Pharmaceuticals reach aquatic environments and are prevalent at small concentrations in wastewater from the drug manufacturing industry and hospitals. Such presence also occurs in domestic wastewater and results from the disposal of unused and expired medicines. Therefore, the objective of this study was to analyze and compare the quantity and quality of publications made by researchers in Arab countries on pharmaceutical wastewater.

    METHODS: To retrieve documents related to pharmaceutical wastewater, we used the Scopus database on November 21, 2015. All documents with terms related to pharmaceutical wastewater in the title or abstract were analysed. Results obtained from Arab countries were compared with those obtained from Turkey, Iran and Israel.

    RESULTS: Globally, a total of 6360 publications were retrieved while those from Arab countries, Iran, Turkey and Israel, were 179, 113, 96 and 54 publications respectively. The highest share of publications belonged to Kingdom of Saudi Arabia (KSA) with a total of 47 (26.2 %) publications, followed by Egypt (38; 21.2 %), Tunisia (17; 9.5 %) and Morocco (16; 8.9 %). The total number of citations was 1635, with a mean of 9.13 and a median (inter quartile range) of 3 (1.0-10.0). The study identified 87 (48.6 %) documents with 32 countries of international collaboration with Arab countries. It was noted that Arab researchers collaborated mainly with authors in Western Europe (54; 30.2 %), followed by authors from the Asiatic region (29; 16.2 %) and Northern America (15; 8.4 %). The most productive institution was King Saud University, KSA (13; 7.3 %), followed by the National Research Centre, Egypt (10; 7.3 %).

    CONCLUSIONS: This study showed that KSA has the largest share of productivity on pharmaceutical wastewater research. Bibliometric analysis demonstrated that research productivity, mainly from Arab countries in pharmaceutical wastewater research, was relatively lagging behind. More research effort is required for Arab countries to catch up with those of non-Arab Middle Easter countries on pharmaceutical wastewater research.

    Matched MeSH terms: Morocco
  8. Fulltext The complete genome sequence of Ensifer meliloti strain CCMM B554 (FSM-MA), a highly effective nitrogen-fixing microsymbiont of Medicago truncatula Gaertn
    Nagymihály M, Vásarhelyi BM, Barrière Q, Chong TM, Bálint B, Bihari P, et al.
    Stand Genomic Sci, 2017;12:75.
    PMID: 29255570 DOI: 10.1186/s40793-017-0298-3
    Strain CCMM B554, also known as FSM-MA, is a soil dwelling and nodule forming, nitrogen-fixing bacterium isolated from the nodules of the legume Medicago arborea L. in the Maamora Forest, Morocco. The strain forms effective nitrogen fixing nodules on species of the Medicago, Melilotus and Trigonella genera and is exceptional because it is a highly effective symbiotic partner of the two most widely used accessions, A17 and R108, of the model legume Medicago truncatula Gaertn. Based on 16S rRNA gene sequence, multilocus sequence and average nucleotide identity analyses, FSM-MA is identified as a new Ensifer meliloti strain. The genome is 6,70 Mbp and is comprised of the chromosome (3,64 Mbp) harboring 3574 predicted genes and two megaplasmids, pSymA (1,42 Mbp) and pSymB (1,64 Mbp) with respectively 1481 and 1595 predicted genes. The average GC content of the genome is 61.93%. The FSM-MA genome structure is highly similar and co-linear to other E. meliloti strains in the chromosome and the pSymB megaplasmid while, in contrast, it shows high variability in the pSymA plasmid. The large number of strain-specific sequences in pSymA as well as strain-specific genes on pSymB involved in the biosynthesis of the lipopolysaccharide and capsular polysaccharide surface polysaccharides may encode novel symbiotic functions explaining the high symbiotic performance of FSM-MA.
    Matched MeSH terms: Morocco
  9. Can clean biomass energy use lower CO2 emissions in African economies? Empirical evidence from dynamic long-run panel framework
    Sulaiman C, Abdul-Rahim AS
    Environ Sci Pollut Res Int, 2020 Oct;27(30):37699-37708.
    PMID: 32607996 DOI: 10.1007/s11356-020-09866-y
    This paper seeks to answer an empirical question of whether clean biomass energy consumption lowers CO2 emissions while controlling for technical innovation in eight selected countries from Africa for the 1980-2015 period. The countries which are chosen based on availability of data on biomass energy and technological innovation include Egypt, Algeria, South Africa, Mauritius, Kenya, Morocco, Tunisia, and Zambia. Applying pooled mean group, mean group, and dynamic fixed effect panel estimators, the results indicate that clean biomass energy use decreases CO2 emission in the long run. But the effect of biomass energy consumption on CO2 emission is insignificant in the short run. The findings imply that CO2 emission can be reduced by increasing clean biomass energy in the energy mix of these countries. Similarly, environmental quality and economic growth can be achieved simultaneously by increasing the share of biomass energy in large-scale production process. Furthermore, the environmental Kuznets curve (EKC), which hypothesizes an inverted U-shaped relationship between CO2 emission and economic growth, was validated in the long run. This suggests that the EKC pattern is only observed in the long run. Thus, as part of recommendation from this study, policy makers in these countries should formulate more policies that will enhance clean biomass energy production and its usage to substitute significant percentage of fossil fuel use in production process.
    Matched MeSH terms: Morocco
  10. Cross-national studies of the impact of levels of living on economic growth: an example
    Scott W
    Int J Health Serv, 1971 Aug;1(3):225-32.
    PMID: 5136228
    Matched MeSH terms: Morocco
  11. Fulltext Association between Physical Activity, Body Composition, and Metabolic Disorders in Middle-Aged Women of Ksar el Kebir (Morocco)
    Harraqui K, Oudghiri DE, Mrabti HN, Hannoun Z, Lee LH, Assaggaf H, et al.
    Int J Environ Res Public Health, 2023 Jan 18;20(3).
    PMID: 36767104 DOI: 10.3390/ijerph20031739
    This study aimed to examine the association between physical activity (PA), body composition, and metabolic disorders in a population of Moroccan women classified by menopausal status. This cross-sectional study comprised 373 peri- and postmenopausal women aged 45-64 years old. PA levels were assessed using the short version of the International Physical Activity Questionnaire (IPAQ-SF). Body composition and metabolic disorders were assessed by measurements of anthropometric and biological parameters: weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), WC/HC ratio, percent body fat, systolic and diastolic blood pressure, fasting blood glucose, and serum lipids (total cholesterol (TC), triglycerides (TG), HDL-C, and LDL-C). Metabolic syndrome (MetS) was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) criteria. Pearson correlations were used to test for associations. The mean total PA score of perimenopausal women was 1683.51 ± 805.36 MET-min/week, and of postmenopausal women was 1450.81 ± 780.67 MET-min/week. In all participants, peri- and postmenopausal women, PA was significantly and inversely associated with BMI, weight, percent body fat, HC, WC, and number of MetS components (p < 0.01), and with fasting blood glucose, TC, TG, and LDL-C (p < 0.05). The frequencies of metabolic disorders, obesity, abdominal obesity, type 2 diabetes, dyslipidemia, and MetS were significantly lower at moderate and intense levels of PA (p < 0.05), in also all participants. In middle-aged women, particularly those who are peri-menopausal, PA at moderate and intense levels is associated with more favorable body composition and less frequent metabolic disorders. However, in this particular study, PA does not appear to be associated with blood pressure and HDL-C concentrations. Future studies may be needed to further clarify these findings.
    Matched MeSH terms: Morocco
  12. Fulltext Enterovirus type 70: the etiologic agent of pandemic acute haemorrhagic conjunctivitis
    Mirkovic RR, Kono R, Yin-Murphy M, Sohier R, Schmidt NJ, Melnick JL
    Bull World Health Organ, 1973;49(4):341-6.
    PMID: 4368683
    A new enterovirus, now classified as enterovirus type 70, was isolated from the conjunctiva of patients with acute haemorrhagic conjunctivitis during the 1971 epidemics that occurred in Japan, Singapore, and Morocco. These epidemics were parts of a pandemic involving Africa (Algeria, Ghana, Morocco, Nigeria, and Tunisia), Asia (Cambodia, China (Province of Taiwan), Hong Kong, India, Indonesia, Japan, Malaysia, the Philippines, Singapore, and Thailand), and England during 1969-71. A representative strain from each of the three epidemic areas was studied cooperatively. The strains exhibited the physicochemical characteristics of enteroviruses. Cross-neutralization tests showed that these viruses were distinct from all known human enterovirus immunotypes, but that they were antigenically closely related. The human origin of the viruses was demonstrated by the appearance of homologous neutralizing antibodies during convalescence in patients with acute haemorrhagic conjunctivitis.
    Matched MeSH terms: Morocco
  13. Cytogenetic profile of patients with clinical spectrum of ambiguous genitalia, amenorrhea, and Turner phenotype: A 21-year single-center experience
    Elkarhat Z, Belkady B, Charoute H, Zarouf L, Razoki L, Aboulfaraj J, et al.
    Am J Med Genet A, 2019 08;179(8):1516-1524.
    PMID: 31207162 DOI: 10.1002/ajmg.a.61257
    The aim of the present study was to determine the frequency and nature of chromosomal abnormalities involved in patients with the clinical spectrum of ambiguous genitalia (AG), amenorrhea, and Turner phenotype, in order to compare them with those reported elsewhere. The study was conducted in the Cytogenetic Department of Pasteur Institute of Morocco, and it reports on the patients who were recruited between 1996 and 2016. Cytogenetic analysis was performed according to the standard method. Among 1,415 patients, chromosomal abnormalities were identified in 7.13% (48/673) of patients with AG, 17.39% (28/161) of patients with primary amenorrhea (PA), 4% (1/25) of patients with secondary amenorrhea, and 23.20% (129/556) of patients with Turner phenotype. However, Turner syndrome was diagnosed in 0.89% (6/673) of patients with AG, 10.56% (17/161) of patients with PA, and 19.78% (110/556) of patients with Turner phenotype. In addition, Klinefelter syndrome and mixed gonadal dysgenesis were confirmed in 2.97% and 1.93% of patients, respectively, with AG, while, chimerism, trisomy 8, and trisomy 13 were confirmed only in 0.15% each. Trisomy 21 was confirmed in patients with AG and Turner phenotype (0.15% and 0.36%, respectively). Moreover, 5.60% (9/161) of patients with PA have been diagnosed as having sex reversal. Thus, the frequency of chromosomal abnormalities observed in Moroccan patients with PA is comparable to that reported in Tunisia, Turkey, Iran, and Hong Kong. However, the frequency is significantly less than that identified in India, Malaysia, Italy, and Romania.
    Matched MeSH terms: Morocco/epidemiology
  14. Comparison of the neurotoxic and myotoxic effects of two Moroccan scorpion venoms and their neutralization by experimental polyclonal antivenom
    Oukkache N, Ahmad Rusmili MR, Othman I, Ghalim N, Chgoury F, Boussadda L, et al.
    Life Sci, 2015 Mar 1;124:1-7.
    PMID: 25623852 DOI: 10.1016/j.lfs.2014.12.031
    Scorpion venoms contain complex mixtures of molecules, including peptides. These peptides specifically bind to various targets, in particular ion channels. Toxins modulating Na(+), K(+), Ca(2+) and Cl(-) currents were described from venoms. The Androctonus and Buthus geni of scorpions are widely distributed in Morocco. Their stings can cause pain, inflammation, necrosis, muscle paralysis and death. The myotoxicity is predominantly associated with neurotoxic effects and is a cause of mortality and morbidity. In this study, pharmacological effects of venoms were investigated in vitro on neuromuscular transmission.
    Matched MeSH terms: Morocco
  15. Fulltext The Health Status of Muslim Women with HIV/AIDS in Arab Countries
    Salih, F.A.M., Haque, Q.M.
    International Medical Journal Malaysia, 2007;6(2):1-5.
    MyJurnal
    The number of people worldwide living with human immunodeficiency virus/ acquired immunodeficiency virus (HIV/AIDS) is more than 40 million, among them 17.7 millions are women (UNAIDS/WHO, 2006) The latest report from the Eastern Mediterranean Region shows that at least one million people are infected with HIV; among them 30% are women. The great majority of reported cases in the Region are men. However, the ratio of men to women cases varies in different countries. It ranges between “9:1 (as for example in Egypt), to 2:1” (as in Morocco and some parts of Yemen). Due to religious, social and cultural values regarding female purity, women and girls living with HIV and AIDS are subjected to greater discrimination than men. WHO reports show that a large percentage of the infected women in Arab countries have contacted the infection from their husbands especially migrants and drug abusers. In Arab countries, studies conducted show that 86% of women choose not to disclose their status of infection for the fear of abandonment, rejection, discrimination, violence, upsetting family members, and accusations of infidelity from their partners, families, and communities. As a result, many women only seek help at the last minute when they are already been terminally ill. Violence against women and girls in its different forms increases women's vulnerability to HIV infection and undermines AIDS control efforts. The fear of violence prevents many women from accessing HIV information, from getting testing and seeking treatment. Stigma and discrimination may also prevent them from carrying out their normal life activities. When women are blamed, this can lead to heightened levels of sexual and domestic violence, abandonment by families and communities, forced abortion or sterilization, dismissal from employment and loss of livelihood opportunities. A study of AIDS-related discrimination in Arab region found that over ten percent of women had lost financial support from family members since being diagnosed as HIV positive. There is a great deal of evidence to establish the significant link between gender-based violence and rising rates of HIV infection among women and girls throughout the world. HIV-positive women must be supported to make their own reproductive choices about whether and/or when to have children. Promote male involvement in sexual and reproductive health programmes. Finally the stigma, discrimination and violations must be stopped.
    Matched MeSH terms: Morocco
  16. Association of TNFRSF13B Gene Polymorphisms With SARS-CoV-2 Infection, Severity, and Humoral Immune Response in a Moroccan Population
    Laazaazia O, Ouladlahsen A, Aqillouch S, Altawalah H, Bouddahab O, Noureddine R, et al.
    Int J Immunogenet, 2025 Apr;52(2):75-87.
    PMID: 40025551 DOI: 10.1111/iji.12709
    BACKGROUND AND AIMS: Genetic factors, including polymorphisms in the TNFRSF13B gene, which regulates humoral immunity, can influence susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study aims to investigate the association between two polymorphisms, rs12603708 and rs3751987, and SARS-CoV-2 susceptibility, disease severity, and humoral immune responses in a Moroccan population.

    MATERIALS AND METHODS: A total of 303 unvaccinated COVID-19 patients (151 severe cases and 152 asymptomatic/moderate cases) and 150 individuals from a SARS-CoV-2-negative group were included in the analysis. Genotyping was performed using TaqMan SNP assays. SARS-CoV-2 antibodies targeting the nucleocapsid protein and IgG antibodies specific to the receptor-binding domain (RBD) were quantified using chemiluminescence microparticles immunoassay. Complete blood counts and C-reactive protein levels were evaluated using an automated platform.

    RESULTS: Our analysis revealed that the A/A genotype of rs12603708 significantly increased the risk of SARS-CoV-2 infection in both codominant (p = 0.0055; OR = 3.74; adjusted p value = 0.022) and recessive (p = 0.0049; OR = 3.17; adjusted p value = 0.022) models, as well as the risk of severe disease (p = 0.014; OR = 3.43; adjusted p value = 0.049). For rs3751987, the G/G genotype was linked to higher susceptibility to infection (p = 0.0011; OR = 2.91; adjusted p value = 0.008), while the G/A genotype appeared protective (p = 0.0007; OR = 0.45; adjusted p value = 0.008). No association was found between rs3751987 and disease severity. Analysis of IgG anti-N and anti-RBD levels revealed no significant associations with either polymorphism (p > 0.05).

    CONCLUSION: These findings highlight the role of TNFRSF13B polymorphisms in SARS-CoV-2 susceptibility and severity, while their impact on humoral immune responses appears limited.

    Matched MeSH terms: Morocco
  17. Children as a resource: environmental degradation and fertility
    Joekes S
    Focus Gend, 1994 Jun;2(2):13-8.
    PMID: 12345527
    Matched MeSH terms: Morocco
  18. Positive policies towards spontaneous settlements
    Oestereich J
    Ekistics, 1981 Jan;48(286):14-8.
    PMID: 12143625
    Matched MeSH terms: Morocco
  19. A second international co-operative investigation into thiacetazone side-effects. Rashes on two thiacetazone containing regimens
    Ferguson GC, Nunn AJ, Fox W, Miller AB, Robinson DK, Tall R
    Tubercle, 1971 Sep;52(3):166-81.
    PMID: 4106401
    Matched MeSH terms: Morocco
  20. The pill in figures and facts
    Von Keep PA
    Adv Fertil Control, 1967;2:1-5.
    PMID: 12275322
    Matched MeSH terms: Morocco
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