Displaying publications 1 - 20 of 260 in total

Abstract:
Sort:
  1. Al-Azri A
    Oman Med J, 2015 Sep;30(5):398.
    PMID: 26421125 DOI: 10.5001/omj.2015.80
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  2. LAWLEY M
    Med J Malaya, 1955 Dec;10(2):126-56.
    PMID: 13308615
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  3. Mohamad I, Nadarajah S
    Oman Med J, 2015 Sep;30(5):397-8.
    PMID: 26421124 DOI: 10.5001/omj.2015.79
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  4. Prasad U
    Med J Malaysia, 1979 Mar;33(3):222-5.
    PMID: 522726
    Matched MeSH terms: Nasopharyngeal Neoplasms/diagnosis*
  5. Ma XR, Sim EU, Ling TY, Tiong TS, Subramaniam SK, Khoo AS
    Malays J Med Sci, 2012 Oct;19(4):23-30.
    PMID: 23613646 MyJurnal
    Ribosomal proteins are traditionally associated with protein biosynthesis until recent studies that implicated their extraribosomal functions in human diseases and cancers. Our previous studies using GeneFishing™ DEG method and microarray revealed underexpression of three ribosomal protein genes, RPS26, RPS27, and RPL32 in cancer of the nasopharynx. Herein, we investigated the expression pattern and nucleotide sequence integrity of these genes in nasopharyngeal carcinoma to further delineate their involvement in tumourigenesis. The relationship of expression level with clinicopathologic factors was also statistically studied.
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  6. Abdullah B, Alias A, Hassan S
    Malays J Med Sci, 2009 Oct;16(4):50-4.
    PMID: 22135512 MyJurnal
    Nasopharyngeal carcinoma (NPC) is a non-lymphomatous, squamous cell carcinoma that occurs in the epithelial lining of the nasopharynx, an area that shows varying degrees of differentiation. Although relatively rare worldwide, NPC has substantial incidence and mortality in populations in Southeast Asia and in people with Southern Chinese ancestry. In Malaysia, NPC is a leading cancer type. In the clinic, NPC presents on a very wide spectrum. Therefore, a high degree of suspicion on the part of the clinician and an increased awareness by the patient is essential for the recognition of an early lesion. Early detection of the cancer is important as it affects the patient's prognosis and the mode of treatment. Managing patients with NPC is very challenging as patients usually present late when the cancer is already in an advanced stage. Here, we review the challenges in the management of NPC.
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  7. Ahmad R, Ishlah W, Azilah N, Rahman JA
    Asian J Surg, 2008 Oct;31(4):174-8.
    PMID: 19010758 DOI: 10.1016/S1015-9584(08)60081-0
    Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign neoplasm that occurs almost exclusively in the nasopharynx of adolescent males. Surgery remains the primary treatment of choice. JNA has always presented a management challenge to surgeons because of its vascular nature, site of occurrence, and local tissue destruction. The surgical approaches are either standard open method which include external or intraoral incisions, or the recent advanced approach, i.e. via using the endonasal endoscope. It is widely accepted that the use of preoperative angiographic embolization reduces the occurrence of intraoperative bleeding and facilitates tumour removal. However, angiographic embolization is not available at all centres. The purpose of this article is to present our experience with five patients diagnosed with JNA who were resected without embolization, using various surgical approaches. Two tumours were removed via endonasal endoscopic surgery. None of the tumours were embolized prior to surgery. We highlight the preoperative evaluation of tumour extent, using both computed tomography (CT) and magnetic resonance angiography, and the importance of temporary clamping of the external carotid artery intraoperatively. Our results suggest that the latter procedure is a safe and effective means of facilitating surgery and reducing intraoperative bleeding.
    Matched MeSH terms: Nasopharyngeal Neoplasms/surgery*
  8. Low QJ, Hon SA, Garry Siow PW, Lim TH, Lee RA, Tan YA, et al.
    QJM, 2020 Oct 01;113(10):753-754.
    PMID: 31995198 DOI: 10.1093/qjmed/hcaa014
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  9. Okekpa SI, S. M. N. Mydin RB, Ganeson S, Gopalan S, Musa MY
    Asian Pac J Cancer Prev, 2020 08 01;21(8):2183-2187.
    PMID: 32856842 DOI: 10.31557/APJCP.2020.21.8.2183
    Heated debates have been on-going about tea consumption and the incidence of cancer, especially in head and
    neck cancer types. This study aimed to review the association between tea consumption habits and nasopharyngeal
    cancer (NPC). Methods: This review was carried out in accordance with the PRISMA-P protocol. Literature search
    for journal articles that published studies on the relationship between tea consumption and NPC was performed via
    databases, such as Elsevier, PubMed, Science Direct, Springer Link, Google, and Google Scholar, for 10 years from
    2008 to 2018. Relevant studies were obtained by applying the pre-determined keywords, such as nasopharyngeal cancer,
    tea consumption and NPC, risk factors of NPC and benefits of tea consumption. Results: A total of 126 articles was
    retrieved. These articles were subjected to eligibility assessment. Six articles remained after applying the inclusion
    criteria. Results suggest that habitual tea consumption reduces NPC. Tea consumption significantly reduces NPC with
    all the studies having a p-value ≤0.05. Meta-analysis showed statistical association between tea consumption and NPC
    risk with OR=0.865 at 95% CI (0.806-0.929). Conclusion: This study suggests that habitual tea consumption could
    be associated with prevention of NPC development. Additional studies are needed to further understand the molecular
    role of bioactive compound and potential health benefit of tea consumption in NPC prevention.
    Matched MeSH terms: Nasopharyngeal Neoplasms/epidemiology*; Nasopharyngeal Neoplasms/prevention & control*
  10. Sakkarapani V, Panicker C
    Med J Malaysia, 1977 Mar;31(3):208-12.
    PMID: 904513
    Matched MeSH terms: Nasopharyngeal Neoplasms/diagnosis*; Nasopharyngeal Neoplasms/pathology
  11. Lim AL, Zahirrudin Z, Pua KC
    Med J Malaysia, 2012 Aug;67(4):428-9.
    PMID: 23082458 MyJurnal
    Nasopharnygeal carcinoma is known to be the commonest tumour of the nasopharynx. However, the incidence of nasopharngeal carcinosarcoma is extremely rare. Carcinosarcoma has been reported to be aggressive in nature and therefore early diagnosis and prompt treatment is important. We report a young lady who was diagnosed with nasopharyngeal carcinosarcoma in our centre. She presented with only 2 weeks history of nose block and was noted to have a mass occupying the nasopharynx with neck metastasis. She underwent panendoscope and biopsy with radical radiotherapy.
    Matched MeSH terms: Nasopharyngeal Neoplasms/diagnosis; Nasopharyngeal Neoplasms/pathology*; Nasopharyngeal Neoplasms/therapy
  12. Irfan M
    Malays Fam Physician, 2013;8(3):54.
    PMID: 25893063
    Matched MeSH terms: Nasopharyngeal Neoplasms
  13. Simons MJ, Chan SH, Day NE, Wee GB, Shanmugaratnam K
    Prog. Clin. Biol. Res., 1977;16:145-8.
    PMID: 905319
    Matched MeSH terms: Nasopharyngeal Neoplasms/genetics; Nasopharyngeal Neoplasms/immunology*; Nasopharyngeal Neoplasms/epidemiology
  14. Prasad U
    JUMMEC, 1996;1(2):23-27.
    Matched MeSH terms: Nasopharyngeal Neoplasms
  15. Lee DW, Teoh DC, Chong FL
    Med J Malaysia, 2015 Apr;70(2):110-1.
    PMID: 26162391 MyJurnal
    We present a case of nasopharyngeal carcinoma complicated with hyperleucocytosis. After ruling our other causes we concluded that the hyperleucocytosis was due to paraneoplastic leukemoid reaction (PLR). The overall survival was 15 months which is rare among patients with PLR.
    Keywords: Sabah
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  16. Teoh JW, Yunus RM, Hassan F, Ghazali N, Abidin ZA
    Rep Pract Oncol Radiother, 2014 Sep;19(5):332-6.
    PMID: 25184058 DOI: 10.1016/j.rpor.2014.02.005
    AIM: The objective of our review is to investigate the association between dermatomyositis patients and nasopharyngeal carcinoma (NPC) together with the clinical presentation of the patients and their management in otorhinolaryngology.
    BACKGROUND: NPC is a malignant disease with good prognosis on early diagnosis. However, the relationship between the dermatomyositis and NPC and its management is not well defined.
    MATERIALS AND METHODS: A 10-year retrospective review of case records of 21 dermatomyositis patients seen in Otorhinolaryngology Department of Hospital Selayang from January 2000 to November 2010.
    RESULTS: These patients ranged from 19 to 74 years old and a total of 8 (38%) out of 21 adults with dermatomyositis were detected to have malignancy. Five out of 8 patients had NPC (62.5%). The mean age of patients with NPC and dermatomyositis was 48 years. NPC is diagnosed in 4 out of 5 patients (80%) in the first year of diagnosis of dermatomyositis. The clinical findings of the examination of nasopharynx ranged from hyperemia to exophytic nasopharyngeal mass. Histologically, it is only related to NPC of WHO types II and III.
    CONCLUSIONS: There is a strong relationship between dermatomyositis and malignancy, especially NPC. Clinicians should have a high index of suspicion for malignancy in all dermatomyositis patients. Rigid nasoendoscopies and biopsies, serum Epstein-Barr viral capsid IgA antibody and imaging studies are helpful in detecting NPC in dermatomyositis patients.
    KEYWORDS: Dermatomyositis; Epstein–Barr viral capsid IgA; Nasopharyngeal carcinoma; Paraneoplastic; WHO histology
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  17. Simons MJ, Chan SH, Wee GB, Shanmugaratnam K, Goh EH, Ho JH, et al.
    PMID: 730194
    New data are presented concerning the relationship between NPC and HLA antigens among Chinese. When attention is confined to newly diagnosed cases, it can be shown that, apart from the increased risk associated with the joint occurrence of A2 and B-Sin 2, there is also an increased risk associated with BW17 and a decrease in risk associated with A11. Among long-term survivors, however, BW17 is appreciably decreased, whereas A2 in the absence of B-Sin 2 or BW17 is increased. Among Malays, a non-Chinese group, there is an excess among NPC patients of a locus A blank, a blank which is probably associated with the AW19 complex.
    Matched MeSH terms: Nasopharyngeal Neoplasms/etiology; Nasopharyngeal Neoplasms/genetics; Nasopharyngeal Neoplasms/immunology*; Nasopharyngeal Neoplasms/mortality
  18. Loke YW
    Br. J. Cancer, 1965 Sep;19(3):482-5.
    PMID: 5833066 DOI: 10.1038/bjc.1965.56
    Matched MeSH terms: Nasopharyngeal Neoplasms/epidemiology; Nasopharyngeal Neoplasms/pathology*
  19. Muhammad Izani S, Irfan M, Suhaimi Y
    Malays Fam Physician, 2011;6(2-3):82-4.
    PMID: 25606231 MyJurnal
    Although nasopharyngeal carcinoma (NPC) is common in this part of the world, the incidence among children is still very low worldwide. The diagnosis is sometimes delayed because of the late reporting of the symptom by the patient or parents, or difficulty in reaching the final diagnosis due to its hidden anatomical location. The challenges include the difficult endoscopy in children, inability to differentiate an adenoid from the tumour on radiograph and often the inconclusive fine needle aspiration findings. If the tumour mass at Fossa of Rosenmuller can be clearly appreciated and biopsied with undoubtedly proven histology of NPC, the diagnosis can be straight forward and treatment can be commenced as early as possible. We report a 10-year-old child presented with bilateral neck cervical lymphadenopathy and epistaxis with fine needle aspiration cytology (FNAC) of the neck mass reported as lymphoma. Further work-up confirmed he was suffering from NPC.
    Matched MeSH terms: Nasopharyngeal Neoplasms*
  20. Pathmanathan R, Kan SP
    Med J Malaysia, 1987 Sep;42(3):212-4.
    PMID: 3147362
    The first two cases of human muscular sarcocystosis are reported from East Malaysia, in Sabalt and Sarawak respectively. Sarcocysts were seen iin biopsied specimen from the nasopharynx of both patients who had carcinoma of the nasopharynx. The measurements and appearances of the cysts and the zoites within the cysts were compared with the human cases of sarcocystosis previously reported in West Malaysia. Zoonotic and other aspects of these cases of East Malaysian sarcocystosis are discussed.
    Matched MeSH terms: Nasopharyngeal Neoplasms/pathology*
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links