Displaying publications 1 - 20 of 189 in total

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  1. Tamam N, Sulieman A, Omer H, Toufig H, Alsaadi M, Salah H, et al.
    Appl Radiat Isot, 2022 Dec;190:110452.
    PMID: 36183658 DOI: 10.1016/j.apradiso.2022.110452
    CT scanning deliver much higher radiation doses than planar radiological procedures, which puts patients to high risks. This study measures and evaluates patient doses during chest and abdomen computed tomography procedures. Particular attention is given to measuring the dose to the equivalent breast (mSv) and to estimate the associated risks of breast cancer to young female patients (15-35 years). Data was obtained from standard examinations from three hospitals. The measured values of CT dose indexes, CTDI (mGy) as well as exposure-related parameters were used for assessment. Breast and effective doses were extrapolated using a software. The results showed remarkable variations of the mean organ equivalent doses for similar CT examinations in the studied hospitals. This could be attributed to the variation in CT scanning imaging technique, and clinical indications. The average effective dose to the chest was 7.9 mSv (2.3-47.0 mSv) and for the abdomen the mean dose was 6.6 mSv, ranging from (3.3-27 mSv). The breast received equivalent doses from chest and abdomen procedures as follows: 10.2 (1.6-33 mSv) and 10.1(2.3-19 mS) Sv respectively. Each procedure yielded high risks of breast cancer for young females. Implementation of accurate referral criteria is recommended to avoid unnecessary breast radiation exposure.
    Matched MeSH terms: Radiation Dosage
  2. Kanaga KC, Yap HH, Laila SE, Sulaiman T, Zaharah M, Shantini AA
    Med J Malaysia, 2010 Jun;65(2):119-22.
    PMID: 23756795 MyJurnal
    Full field digital mammography (FFDM) has been progressively introduced in medical centers in recent years. However, it is questionable which exposure parameters are suitable in order to reduce the glandular breast doses as they are related to induced carcinogenesis. The goal of this study was to compare the average glandular doses (AGD) and image quality of three FFDM systems namely Siemens Mammomat NovationDR, Hologic Lorad Selenia and General Electric Senographe Essential using a Figure of Merit. A Computerized Imaging Reference Systems (CIRS) tissue equivalent breast phantom which consists of phototimer compensation plate with different thickness and glandularity was exposed in fully automatic exposure control mode in the cranio-caudal projection similar to clinical settings. Thermoluminescent dosimeter 100H (TLD- 100H) was used to measure the entrance surface air kerma (ESAK), the AGD was calculated using European protocol whilst the image quality was assessed quantitatively by measuring the contrast to noise ratio (CNR) value. The obtained values were used to calculate the Figure of Merit (FOM) to analyze the effectiveness of the system. Repeated Measures ANOVA analysis showed that there is a significant difference (p<0.05) in the mean value of AGD and CNR between the three FFDM systems. Hologic Lorad Selenia system contrbuted the highest AGD value while General Electric Senographe Essential had the highest CNR and FOM value. In conclusion, this study may provide an objective criterion during the selection of a mammography unit by using the figure of merit for screening or diagnostic purpose.
    Matched MeSH terms: Radiation Dosage*
  3. Ng KH, Rassiah P, Wang HB, Hambali AS, Muthuvellu P, Lee HP
    Br J Radiol, 1998 Jun;71(846):654-60.
    PMID: 9849390
    A collaborative national survey initiated by the University of Malaya and the Ministry of Health was conducted from 1993 to 1995 to establish baseline patient dose data for seven common types (12 projections) of X-ray examinations in Malaysia. A total of 12 randomly selected public hospitals and 867 patients were included in this survey. The entrance surface doses (ESD) received by the patients were measured using thermoluminescent dosemeters (TLDs) attached to the patient's skin. Histograms are presented showing wide, positively skewed distributions of measured entrance surface doses for each examination. Mean, median, first and third quartile values of ESD and median effective dose are reported. Survey results are generally comparable with those reported in the UK, USA and by the International Atomic Energy Agency (IAEA). The results also provide information on dose level for a lower weight population (mean weight 60 kg) compared with the international reference dose values based on a 70 kg standard. The findings support the importance of the on-going national quality assurance programme to ensure doses are kept to a level consistent with optimum image quality. The data will also be useful for the formulation of national guidance levels as recommended by the IAEA. Furthermore, this study provides patient dosimetry information on healthcare level II countries.
    Matched MeSH terms: Radiation Dosage*
  4. Ramanaidu S, Sta Maria R, Ng Kh, George J, Kumar G
    Biomed Imaging Interv J, 2006 Jul;2(3):e35.
    PMID: 21614244 MyJurnal DOI: 10.2349/biij.2.3.e35
    A study of radiation dose and image quality following changes to the tube potential (kVp) in paediatric chest radiography.
    Matched MeSH terms: Radiation Dosage
  5. Mustafa IS, Kamari HM, Yusoff WM, Aziz SA, Rahman AA
    Int J Mol Sci, 2013;14(2):3201-14.
    PMID: 23380963 DOI: 10.3390/ijms14023201
    Spectrophotometric studies of lead borotellurite glasses were carried out before and after gamma irradiation exposure. The increasing peak on the TeO(4) bi-pyramidal arrangement and TeO(3+1) (or distorted TeO(4)) is due to augmentation of irradiation dose which is attributed to an increase in degree of disorder of the amorphous phase. The structures of lead tellurate contain Pb(3)TeO(6) consisting of TeO(3) trigonal pyramid connected by PbO(4) tetragonal forming a three-dimensional network. The decrease of glass rigidity is due to irradiation process which is supported by the XRD diffractograms results. The decreasing values of absorption edge indicate that red shift effect occur after irradiation processes. A shift in the optical absorption edge attributed to an increase of the conjugation length. The values of optical band gap, E(opt) were calculated and found to be dependent on the glass composition and radiation exposure. Generally, an increase and decrease in Urbach's energy can be considered as being due to an increase in defects within glass network.
    Matched MeSH terms: Radiation Dosage
  6. Moey, Soo-Foon, Nur Farah Hani Muhd Jaafar, Nursyahirah Saidin
    MyJurnal
    Introduction: Various medium and high tube potentials were utilized to conduct chest x-rays. There
    are advantages and disadvantages with regards to image quality and radiation dose when using
    medium and high kilovoltage (kVp) technique. However, radiographers have misconstrued
    understanding pertaining to the choice of tube potential as well as grid usage when performing chest radiography. Methods: The experimental study was conducted using the PBU-50 phantom by exposing it with medium kVp utilizing grid and non-grid as well as high kVp with grid. All images obtained were evaluated using the modified evaluation criteria for PA chest established by the Commission of European Communities, 1996 whilst the dose area product (DAP) was determined using the Dose Area Product (DAP) meter. The value obtained from the DAP meter was converted to entrance surface dose (ESD) usingCALDOSE_X5.0 software and mathematical formula. Results: The Wilcoxon Signed-Rank Test indicated a significant difference in ESD when using medium and high kVp; Z= -2.666, p
    Matched MeSH terms: Radiation Dosage
  7. Nurshuhada Ali, Zafri Azran Abdul Majid, Mohd Syahriman Mohd Azmi
    MyJurnal
    The ideal imaging system that is providing a good quality image of minimal radiation dose. There are many parameters that influenced image quality and radiation dose on clinical radiography. This study has identified some of the problems whereby there are practitioners do not select the proper size of image receptor (IR) and collimation during the examination. The re-usable of the IR and imaging plate also need to be concerned whether multiple exposures may affect the image
    quality or not. The purpose of this study is to investigate the effect of different exposure settings; kVp, mAs, collimation field sizes and different IR’ sizes for image quality and radiation dose. Methods: The wall-mounted x-ray machine act as a sources of radiation which exposed the acrylic cylinder that placed over the IR. The examination is repeated with different kVp, mAs, collimation field sizes and IR’s sizes. The source to image distance (SID) is fixed to 100 cm distance and put Nano dot dosimeter similar level with the top of acrylic to measure the dose. The result analysed by using software ImageJ to measure the Contrast to Noise Ratio (CNR). Results: The percentage of CNR1 and CNR2 reduced as the kVp is increased from (CNR1=77.25, CNR2=64.45), (CNR1=73.47, CNR2=61.22) and (CNR1=62.80, CNR2=57.32) for 50 kVp, 75 kVp and 100 kVp respectively and fluctuate when mAs increased. The CNR and entrance skin dose (ESD) shows higher when x-ray beam collimate according to IR’s size. Conclusions: Overall, the manipulative effect of exposure settings on image quality and ESD shows some positive results. The result also shows inconsistent readings in the CNR and ESD. The percentage of CNR decreased when kVp increases and slightly fluctuate when mAs increased. The ESD reading depicts higher when the kVp and mAs increase as well as when x-ray beam collimated according to IR’s sizes.
    Matched MeSH terms: Radiation Dosage
  8. Rizk C, Askounis P, Okyar HB, Sangau JK, Baradaran S, Al Fares E, et al.
    Radiat Prot Dosimetry, 2020 Aug 28;190(2):217-225.
    PMID: 32696972 DOI: 10.1093/rpd/ncaa093
    This paper presents the results of the evaluation of the uncertainty in measurement of the personal dose equivalent, Hp(10), at nine individual monitoring services (IMSs) in Asia and the Pacific region. Different types of passive dosemeters were type-tested according to the International Electrotechnical Commission 62387 requirements. The uncertainty in measurement was calculated using the Guide to the Expression of Uncertainty in Measurement approach. Expanded uncertainties ranged between 24 and 86% (average = 38%) for Hp(10) values around 1 mSv and between 14 and 40% (average = 27%) for doses around the annual dose limit, Hp(10) = 20 mSv. The expanded uncertainties were lower than the 1.5 factor in either direction proposed by the International Commission on Radiological Protection for doses near the relevant dose limits. This indicates an acceptable level of uncertainty for all participating IMSs. Uncertainty evaluation will help the IMSs to acknowledge the accuracy of their measurements.
    Matched MeSH terms: Radiation Dosage
  9. Samat S, Evans C
    Sains Malaysiana, 2011;40:1355-1358.
    Eleven different brands of mineral water available in Malaysia were assessed in comparison with two criteria for ingested radiation dose. It is concluded that mineral water can only contribute a very small fraction of the typical daily intake of potassium, and that the radiation dose acquired from any of the brands can never exceed a small fraction of the recommended limits.
    Matched MeSH terms: Radiation Dosage
  10. Sulieman A, Mayhoub F, Ibrahim HS, Omer H, Alkhorayef M, Abolaban FA, et al.
    Radiat Prot Dosimetry, 2021 Oct 12;195(3-4):314-318.
    PMID: 34265851 DOI: 10.1093/rpd/ncab107
    The objective of this study is to estimate the annual effective dose for cardiologists and nurses by measuring Hp(10) and Hp(0.07) during cardiac catheterization procedures. A total of 16 staffs members were working in interventional cardiology during 1 year at a tertiary hospital. The occupational dose was measured using calibrated thermo-luminescent dosemeters (TLD-100, LiF:Mg,Ti). The overall mean and range of the annual Hp(10) and Hp(0.07) (mSv) for cardiologists were 3.7 (0.13-14.5) and 3.2 (0.21-14.7), respectively. Cardiologists were frequently exposed to higher doses compared with nurses and technologists. The exposure showed wide variations, which depend on occupation and workload. Staff is adhered to radiation protection guidelines regarding shielding the trunk, thyroid shield, thus appropriately protected. Lens dose measurement is recommended to ensure that dose limit is not exceeded.
    Matched MeSH terms: Radiation Dosage
  11. Norsuddin NM, Mei Sin JG, Ravintaran R, Arasaratnam S, Abdul Karim MK
    Appl Radiat Isot, 2023 Feb;192:110525.
    PMID: 36436228 DOI: 10.1016/j.apradiso.2022.110525
    This study compares the mean glandular dose (MGD) across 2D, 3D projection and Contrast-Enhanced Digital Mammography (CEDM) mammographic techniques. The important metadata were extracted from the digital mammography console. 650 subjects were clustered based on projections, age and CBT. The MGD of 2D, 3D, and CEDM was positively correlated with CBT but inversely correlated with the age factor. This study indicate MGD of CEDM was 16% and 22% lower compared to 2D and 3D techniques, respectively.
    Matched MeSH terms: Radiation Dosage
  12. Sulieman A, Salah H, Rabbaa M, Abuljoud M, Alkhorayef M, Tahir D, et al.
    Appl Radiat Isot, 2023 Mar;193:110626.
    PMID: 36640699 DOI: 10.1016/j.apradiso.2022.110626
    Breast cancer is a common malignancy for females (25% of female cancers) and also has low incidence in males. It was estimated that 1% of all breast malignancies occur in males with mortality rate about 20%, with annual increase in incidence. Risk factors include age, family history, exposure to ionizing radiation and high estrogen and low of androgens hormones level. Diagnosis and screening are challenging due to limiting effectiveness of breast cancer screening. Therefore, patients may expose to ionizing radiation that may contribute in breast cancer incidence in males. In literature, limited studies were published regarding radiation exposure for males during mammography. The objective of this research is to quantify patient doses during male mammogram and to estimate the projected radiogenic risk during the procedure. In total, 42 male patients were undergone mammogram for breast cancer diagnosis during two consecutive years. The mean and range of patient age (years) is 45 (23-80). The mean and standard deviation (SD) of the peak tube potential and tube current time product are 28.64 ± 2. and 149 ± 35.1, respectively. The mean, and range of patients' entrance surface air kerma (ESAK, mGy) per single breast procedure was 5.3 (0.47-27.5). Male patient's received comparable radiation dose per mammogram compared to female procedures. With increasing incidence of male breast cancer, proper guidelines are necessary for the mammographic procedure are necessary to reduce unnecessary radiation doses and radiogenic risk.
    Matched MeSH terms: Radiation Dosage
  13. Osman ND, Abdulkadir MK, Shuaib IL, Nasirudin RA
    Radiography (Lond), 2024 Jan;30(1):237-244.
    PMID: 38035439 DOI: 10.1016/j.radi.2023.11.012
    INTRODUCTION: The adoption of size-specific dose estimate (SSDE) in clinical practice is still limited owing to the tedious and complex manual measurement of individual patient size for the clinical calculation of SSDE. Thus, the automation of SSDE is imperative. This study aims to evaluate a predictive equation for the automated calculation of SSDE.

    METHODS: A user-friendly software was developed to accurately predict the individual size-specific dose estimation of paediatric patients undergoing computed tomography (CT) scans of the head, thorax, and abdomen. The software includes a calculation equation developed based on a novel SSDE prediction equation that used a population's pre-determined percentage difference between volume-weighted computed tomography dose index (CTDIvol) and SSDE with age. American Association of Physicists in Medicine (AAPM RPT 204) method (manual) and segmentation-based SSDE calculators (indoseCT and XXautocalc) were used to assess the proposed software predictions comparatively.

    RESULTS: The results of this study show that the automated equation-based calculation of SSDE and the manual and segmentation-based calculation of SSDE are in good agreement for patients. The differences between the automated equation-based calculation of SSDE and the manual and segmentation-based calculation are less than 3%.

    CONCLUSION: This study validated an accurate SSDE calculator that allows users to enter key input values and calculate SSDE.

    IMPLICATION FOR PRACTICE: The automated equation-based SSDE software (PESSD) seems a promising tool for estimating individualised CT doses during CT scans.

    Matched MeSH terms: Radiation Dosage
  14. Salehi Z, Ya Ali NK, Yusoff AL
    Appl Radiat Isot, 2012 Nov;70(11):2586-9.
    PMID: 22940409 DOI: 10.1016/j.apradiso.2011.12.007
    BEAMnrc was used to derive the X-ray spectra, from which HVL and homogeneity coefficient were determined, for different kVp and filtration settings. Except for the peak at 61 keV, the spectra are in good agreement with the IPEM report 78 data for the case of filtered beams, whereas the unfiltered beams exhibit softer spectra. Although the current attenuation data deviates from the IPEM 78 data by ~±0.5%, this has negligible effects on the calculated HVL values.
    Matched MeSH terms: Radiation Dosage*
  15. Yahya N, Manan HA
    World Neurosurg, 2019 Oct;130:e188-e198.
    PMID: 31326352 DOI: 10.1016/j.wneu.2019.06.027
    BACKGROUND: Diffusion tensor imaging (DTI), which visualizes white matter tracts, can be integrated to optimize intracranial radiation therapy (RT) and radiosurgery (RS) treatment planning. This study aimed to systematically review the integration of DTI for dose optimization in terms of evidence of dose improvement, clinical parameter changes, and clinical outcome in RT/RS treatment planning.

    METHODS: PubMed and Scopus electronic databases were searched based on the guidelines established by PRISMA to obtain studies investigating the integration of DTI in intracranial RT/RS treatment planning. References and citations from Google Scholar were also extracted. Eligible studies were extracted for information on changes in dose distribution, treatment parameters, and outcome after DTI integration.

    RESULTS: Eighteen studies were selected for inclusion with 406 patients (median study size, 19; range: 2-144). Dose distribution, with or without DTI integration, described changes of treatment parameters, and the reported outcome of treatment were compared in 12, 7, and 10 studies, respectively. Dose distributions after DTI integration improved in all studies. Delivery time or monitor unit was higher after integration. In studies with long-term follow-up (median, >12 months), neurologic deficits were significantly fewer in patients with DTI integration.

    CONCLUSIONS: Integrating DTI into RT/RS treatment planning improved dose distribution, with higher treatment delivery time or monitor unit as a potential drawback. Fewer neurologic deficits were found with DTI integration.

    Matched MeSH terms: Radiation Dosage*
  16. Sanusi MSM, Ramli AT, Hashim S, Lee MH
    Ecotoxicol Environ Saf, 2021 Jan 15;208:111727.
    PMID: 33396058 DOI: 10.1016/j.ecoenv.2020.111727
    Continuous depletion in tin productions has led to a newly emerging industry that is a tin by-product (amang) processing industry to harness mega tons of tin by-products produced in the past. Amang composed of profitable multi-heavy minerals and rare-earth elements. With poorly established safety and health practices in operating plant, amang poses extremely high radioactivity problem associated with high occupational ionizing radiation exposures to workers and continuously impacting the local environment with radioactive contamination from industrial effluent and solid waste into lithosphere and water bodies. The radioactivity level of 238U and 232Th series in the mineral varies from few hundreds up to ~200,000 and ~400,000 Bq kg-1 respectively and are potential to yield more than ~ 30,000 nGy h-1 of gamma (γ) radiation exposure to plant workers. The study found out that for 8 h of work time, a worker is estimated to receive an average effective dose of 0.1 mSv per day from external γ radiation source with a maximum up to 2 mSv per day for extreme exposure situation. Interferences of different exposure routes for examples inhalation of equivalent equilibrium concentration (ECC) of 222Rn and 220Rn progenies and airborne long-lived α particles from the dusty working environment could pose a higher total effective dose as much as 5 mSv per day and 115 mSv per year. The value is 5 times higher than the annual dose limit for designated radiation worker (20 mSv) in Peninsular Malaysia. The study found that 41% of the total received an effective dose received by a worker is contributed by 222Rn, 32% of airborne particulates and dust, 23% from external γ exposure and 4% from 220Rn. Based on radioecological risk assessment, the study found out that the aquatic environment is the highly exposed group to ionizing radiation from industrial effluent discharge and sand residues. With the impotent establishment of radiation protection in the industry, plus the country newly introduced long-term plan to revive tin mining as well as its accessory amang mineral, it is necessary for the government to harmonize current regulation to improve the worker safety and health as well as sustaining local environment.
    Matched MeSH terms: Radiation Dosage*
  17. Hassan WB, Osman H, Alosaimi M, AbuRkbah A, AlQurashi A, Elkhader BA, et al.
    Appl Radiat Isot, 2024 Sep;211:111386.
    PMID: 38870555 DOI: 10.1016/j.apradiso.2024.111386
    BACKGROUND: Radiation is an integral part of routine medical practice, but it carries a risk to the health of medical staff. Hence, it should be assessed periodically. The study's goal was to quantify the levels of radiation exposure for medical staff at King Faisal Medical Complex (KFMC), Taif City Saudi Arabia, and to assess their radiation protective procedures in practice.

    METHODS: The study looked at the thermoluminescence dosimeters (TLDs) records of 50 medical professionals who were exposed to radiation while working at KFMC from 2019 to 2020 in Taif city, Saudi Arabia. In Riyadh, radiation exposure is read from skin TLDs using Harshaw model 6600 plus detectors. The Excel software was utilized to process the obtained data for calculating effective doses. A questionnaire was also distributed to the medical staff to assess their radiation protection procedures. The Statistical Package for Social Sciences (SPSS) program version 23 was used to analyze the obtained data.

    RESULTS: The mean annual effective doses of the medical staff in 2019 and 2020 were determined to be 1.14 mSv and 1.4645 mSv, respectively, with no significant difference in effective doses between males and females in either year. The socio-demographic features of the medical personnel were examined, and the findings revealed that the majority of participants were male radiological technologists. The rate of adherence to radiation protection techniques was 68%, with a normally distributed dispersal. The amount of adherence varied significantly depending on nationality, occupation, and academic qualification.

    CONCLUSION: According to the research, the mean annual effective dosage for medical professionals at KFMC was significantly below the recommended level, indicating satisfactory compliance with the ALARA radiation safety concept.

    Matched MeSH terms: Radiation Dosage*
  18. Tan SK, Yeong CH, Ng KH, Abdul Aziz YF, Sun Z
    PLoS One, 2016;11(8):e0161543.
    PMID: 27552224 DOI: 10.1371/journal.pone.0161543
    OBJECTIVES: This study aimed to measure the absorbed doses in selected organs for prospectively ECG-triggered coronary computed tomography angiography (CCTA) using five different generations CT scanners in a female adult anthropomorphic phantom and to estimate the effective dose (HE).

    MATERIALS AND METHODS: Prospectively ECG-triggered CCTA was performed using five commercially available CT scanners: 64-detector-row single source CT (SSCT), 2 × 32-detector-row-dual source CT (DSCT), 2 × 64-detector-row DSCT and 320-detector-row SSCT scanners. Absorbed doses were measured in 34 organs using pre-calibrated optically stimulated luminescence dosimeters (OSLDs) placed inside a standard female adult anthropomorphic phantom. HE was calculated from the measured organ doses and compared to the HE derived from the air kerma-length product (PKL) using the conversion coefficient of 0.014 mSv∙mGy-1∙cm-1 for the chest region.

    RESULTS: Both breasts and lungs received the highest radiation dose during CCTA examination. The highest HE was received from 2 × 32-detector-row DSCT scanner (6.06 ± 0.72 mSv), followed by 64-detector-row SSCT (5.60 ± 0.68 and 5.02 ± 0.73 mSv), 2 × 64-detector-row DSCT (1.88 ± 0.25 mSv) and 320-detector-row SSCT (1.34 ± 0.48 mSv) scanners. HE calculated from the measured organ doses were about 38 to 53% higher than the HE derived from the PKL-to-HE conversion factor.

    CONCLUSION: The radiation doses received from a prospectively ECG-triggered CCTA are relatively small and are depending on the scanner technology and imaging protocols. HE as low as 1.34 and 1.88 mSv can be achieved in prospectively ECG-triggered CCTA using 320-detector-row SSCT and 2 × 64-detector-row DSCT scanners.

    Matched MeSH terms: Radiation Dosage*
  19. Adhimoolam SK, Kumar S, Manojkumar T, Devanand BL, Elango N, Govindarajan N, et al.
    Radiat Prot Dosimetry, 2024 Nov 18;200(19):1926-1932.
    PMID: 39375206 DOI: 10.1093/rpd/ncae199
    The purpose of this study was to assess local diagnostic reference levels (LDRLs) for full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) mammography in India. Data from 1500 women were collected from five different mammography facilities in major cities in Tamil Nadu, India. The mean of mean glandular dose were used to arrive at an LDRL. The noted mean compressed breast thickness was 55.26 ± 3.4. The recorded mean MGDs for the five centres were 3.1 ± 0.1 and 3.8 ± 0.2 mGy for FFDM and DBT, respectively. The 75th percentile value for all five centers is 3.3 and 4.0 mGy for FFDM and DBT, respectively. The LDRLs found in the current study were also compared with those from earlier studies conducted in other nations, such as the United Kingdom, Malaysia, Morocco, and Ghana. The present study is the first of its kind to determine the LDRL for the FFDM and DBT scanners operating in the Tamil Nadu region, India, and is proposed as a starting point that will allow professionals to evaluate and optimize their practice. Furthermore, similar studies in other regions of India are necessary in order to establish National DRLs.
    Matched MeSH terms: Radiation Dosage*
  20. Aloufi KM, Gameraddin M, Alhazmi FH, Almazroui IS, Osman H, Khandaker MU
    Appl Radiat Isot, 2025 Jan;215:111583.
    PMID: 39522393 DOI: 10.1016/j.apradiso.2024.111583
    BACKGROUND: Nuclear medicine diagnostic and treatment procedures represent significant sources of ionizing radiation exposure for both staff and patients. Consequently, assessing and optimizing radiation doses are crucial to minimize potential side effects.

    AIM: This study seeks to evaluate the effective radiation doses associated with common diagnostic and treatment procedures, as well as propose diagnostic reference levels (DRLs), within two nuclear medicine centers in Madinah, Saudi Arabia.

    METHODOLOGY: Data from 445 patients were gathered from two nuclear medicine centers in the Madinah region of Saudi Arabia. The data were categorized based on the type of nuclear medicine (NM) procedure, the chemical composition of the administered radiopharmaceutical, as well as patient age and weight. Effective radiation doses for prevalent NM procedures were computed, and suggested DRLs were formulated.

    RESULTS: Effective radiation doses were analyzed for 16 adult and 2 pediatric NM procedures (divided into 8 groups). The effective radiation doses for adult diagnostic nuclear medicine procedures range from 0.05 mSv (Nanocoloid) to 29 mSv (67Ga-citrate). For pediatric procedures, the doses range from 0.80 mSv (5-year-old undergoing renal DTPA) to 1.6 mSv (1-year-old undergoing renal DMSA). Furthermore, DRL values were determined for both adult and pediatric NM procedures. The study's findings demonstrated a high degree of concordance between effective radiation doses and DRL values, aligning well with previously published research.

    CONCLUSION: While the effective radiation doses outlined in this study were generally within acceptable limits and consistent with prior research findings, optimizing radiation doses remains imperative, particularly for pediatric NM procedures.

    Matched MeSH terms: Radiation Dosage*
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