Browse publications by year: 2015

  1. Culbert GJ, Waluyo A, Iriyanti M, Muchransyah AP, Kamarulzaman A, Altice FL
    Drug Alcohol Depend, 2015 Apr 01;149:71-9.
    PMID: 25659895 DOI: 10.1016/j.drugalcdep.2015.01.018
    BACKGROUND: In Indonesia, incarceration of people who inject drugs (PWID) and access to drugs in prison potentiate within-prison drug injection (WP-DI), a preventable and extremely high-risk behavior that may contribute substantially to HIV transmission in prison and communities to which prisoners are released.

    AIMS: This mixed method study examined the prevalence, correlates, and social context of WP-DI among HIV-infected male prisoners in Indonesia.

    METHODS: 102 randomly selected HIV-infected male prisoners completed semi-structured voice-recorded interviews about drug use changes after arrest, drug use cues within prison, and impact of WP-DI on HIV and addiction treatment. Logistic regression identified multivariate correlates of WP-DI and thematic analysis of interview transcripts used grounded-theory.

    RESULTS: Over half (56%) of participants reported previous WP-DI. Of those, 93% shared injection equipment in prison, and 78.6% estimated sharing needles with ≥ 10 other prisoners. Multivariate analyses independently correlated WP-DI with being incarcerated for drug offenses (AOR = 3.29, 95%CI = 1.30-8.31, p = 0.011) and daily drug injection before arrest (AOR = 5.23, 95%CI = 1.42-19.25, p = 0.013). Drug availability and proximity to drug users while incarcerated were associated with frequent drug craving and escalating drug use risk behaviors after arrest. Energetic heroin marketing and stigmatizing attitudes toward methadone contribute to WP-DI and impede addiction and HIV treatment.

    CONCLUSIONS: Frequent WP-DI and needle sharing among these HIV-infected Indonesian prison inmates indicate the need for structural interventions that reduce overcrowding, drug supply, and needle sharing, and improve detection and treatment of substance use disorders upon incarceration to minimize WP-DI and associated harm.

    MeSH terms: Adult; Attitude; Heroin; Humans; Indonesia/epidemiology; Male; Methadone/therapeutic use; Opioid-Related Disorders/rehabilitation; Narcotics/therapeutic use; Prisoners/psychology*; Prisons*; Risk-Taking; HIV Infections/epidemiology*; HIV Infections/psychology*; Substance Abuse, Intravenous/epidemiology*; Substance Abuse, Intravenous/psychology*; Prevalence; Needle Sharing
  2. Prakash A, Bharti K, Majeed AB
    Fundam Clin Pharmacol, 2015 Apr;29(2):131-49.
    PMID: 25659970 DOI: 10.1111/fcp.12110
    Zinc is the authoritative metal which is present in our body, and reactive zinc metal is crucial for neuronal signaling and is largely distributed within presynaptic vesicles. Zinc also plays an important role in synaptic function. At cellular level, zinc is a modulator of synaptic activity and neuronal plasticity in both development and adulthood. Different importers and transporters are involved in zinc homeostasis. ZnT-3 is a main transporter involved in zinc homeostasis in the brain. It has been found that alterations in brain zinc status have been implicated in a wide range of neurological disorders including impaired brain development and many neurodegenerative disorders such as Alzheimer's disease, and mood disorders including depression, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and prion disease. Furthermore, zinc has also been implicated in neuronal damage associated with traumatic brain injury, stroke, and seizure. Understanding the mechanisms that control brain zinc homeostasis is thus critical to the development of preventive and treatment strategies for these and other neurological disorders.
    MeSH terms: Animals; Biological Transport/physiology; Brain/metabolism*; Brain/pathology; Brain Diseases/diagnosis; Brain Diseases/metabolism*; Brain Injuries/diagnosis; Brain Injuries/metabolism; Homeostasis/physiology; Humans; Zinc/metabolism*; Neurodegenerative Diseases/diagnosis; Neurodegenerative Diseases/metabolism; Stroke/diagnosis; Stroke/metabolism; Cation Transport Proteins/metabolism
  3. Mohd-Yusoff NF, Ruperao P, Tomoyoshi NE, Edwards D, Gresshoff PM, Biswas B, et al.
    G3 (Bethesda), 2015 Apr;5(4):559-67.
    PMID: 25660167 DOI: 10.1534/g3.114.014571
    Genetic structure can be altered by chemical mutagenesis, which is a common method applied in molecular biology and genetics. Second-generation sequencing provides a platform to reveal base alterations occurring in the whole genome due to mutagenesis. A model legume, Lotus japonicus ecotype Miyakojima, was chemically mutated with alkylating ethyl methanesulfonate (EMS) for the scanning of DNA lesions throughout the genome. Using second-generation sequencing, two individually mutated third-generation progeny (M3, named AM and AS) were sequenced and analyzed to identify single nucleotide polymorphisms and reveal the effects of EMS on nucleotide sequences in these mutant genomes. Single-nucleotide polymorphisms were found in every 208 kb (AS) and 202 kb (AM) with a bias mutation of G/C-to-A/T changes at low percentage. Most mutations were intergenic. The mutation spectrum of the genomes was comparable in their individual chromosomes; however, each mutated genome has unique alterations, which are useful to identify causal mutations for their phenotypic changes. The data obtained demonstrate that whole genomic sequencing is applicable as a high-throughput tool to investigate genomic changes due to mutagenesis. The identification of these single-point mutations will facilitate the identification of phenotypically causative mutations in EMS-mutated germplasm.
    MeSH terms: Alkylating Agents/chemistry*; Ethyl Methanesulfonate/chemistry*; Gene Frequency; Phenotype; Sequence Analysis, DNA; DNA, Plant/analysis; DNA, Plant/chemistry; Genome, Plant*; Base Pairing; Polymorphism, Single Nucleotide; Lotus/genetics*; Genetic Loci; High-Throughput Nucleotide Sequencing
  4. Kondorosy E, Fábics A
    Zootaxa, 2015 Jan 05;3904(1):95-104.
    PMID: 25660773 DOI: 10.11646/zootaxa.3904.1.5
    The previously known distribution area of the genus Grossander Slater, 1976 (Hemiptera, Heteroptera, Rhyparochromidae, Drymini) is broadened with the description of two new species: Grossander papuanus sp. nov. (New Guinea) and Grossander eylesi sp. nov. (Burma, Laos, Thailand, Malaysia and Indonesia). Grossander (Oculoander) subgen. nov. is created for these new taxa. Drawings of habitus and male genitalia are presented. Keys to the subgenera of Grossander, and to the species of the new subgenus are provided.
    MeSH terms: Animals; Animal Structures/anatomy & histology; Animal Structures/growth & development; Asia; Female; Male; Organ Size; Heteroptera/anatomy & histology; Heteroptera/classification*; Heteroptera/growth & development; Body Size; Animal Distribution
  5. Ali ME, Razzak MA, Hamid SB, Rahman MM, Amin MA, Rashid NR, et al.
    Food Chem, 2015 Jun 15;177:214-24.
    PMID: 25660879 DOI: 10.1016/j.foodchem.2014.12.098
    Food falsification has direct impact on public health, religious faith, fair-trades and wildlife. For the first time, here we described a multiplex polymerase chain reaction assay for the accurate identification of five meat species forbidden in Islamic foods in a single assay platform. Five pairs of species-specific primers were designed targeting mitochondrial ND5, ATPase 6, and cytochrome b genes to amplify 172, 163, 141, 129 and 108 bp DNA fragments from cat, dog, pig, monkey and rat meats, respectively. All PCR products were identified in gel-images and electrochromatograms obtained from Experion Bioanalyzer. Species-specificity checking against 15 important meat and fish and 5 plant species detected no cross-species amplification. Screening of target species in model and commercial meatballs reflected its application to detect target species in process foods. The assay was tested to detect 0.01-0.02 ng DNA under raw states and 1% suspected meats in meatball formulation.
    MeSH terms: Animals; Haplorhini; Cats; DNA/analysis*; DNA/genetics; Dogs; Food Handling; Islam*; Meat/analysis*; Meat Products/microbiology*; Swine; Polymerase Chain Reaction/methods*; Rats
  6. Abdulra'uf LB, Tan GH
    Food Chem, 2015 Jun 15;177:267-73.
    PMID: 25660885 DOI: 10.1016/j.foodchem.2015.01.031
    An HS-SPME method was developed using multivariate experimental designs, which was conducted in two stages. The significance of each factor was estimated using the Plackett-Burman (P-B) design, for the identification of significant factors, followed by the optimization of the significant factors using central composite design (CCD). The multivariate experiment involved the use of Minitab® statistical software for the generation of a 2(7-4) P-B design and CCD matrices. The method performance evaluated with internal standard calibration method produced good analytical figures of merit with linearity ranging from 1 to 500 μg/kg with correlation coefficient greater than 0.99, LOD and LOQ were found between 0.35 and 8.33 μg/kg and 1.15 and 27.76 μg/kg respectively. The average recovery was between 73% and 118% with relative standard deviation (RSD=1.5-14%) for all the investigated pesticides. The multivariate method helps to reduce optimization time and improve analytical throughput.
    MeSH terms: Fruit/chemistry*; Gas Chromatography-Mass Spectrometry/methods*; Pesticide Residues/analysis*; Pesticide Residues/chemistry; Vegetables/chemistry*; Multivariate Analysis; Solid Phase Microextraction/methods*
  7. Low KH, Zain SM, Abas MR, Md Salleh K, Teo YY
    Food Chem, 2015 Jun 15;177:390-6.
    PMID: 25660902 DOI: 10.1016/j.foodchem.2015.01.059
    The trace metal concentrations in edible muscle of red tilapia (Oreochromis spp.) sampled from a former tin mining pool, concrete tank and earthen pond in Jelebu were analysed with microwave assisted digestion-inductively coupled plasma-mass spectrometry. Results were compared with established legal limits and the daily ingestion exposures simulated using the Monte Carlo algorithm for potential health risks. Among the metals investigated, arsenic was found to be the key contaminant, which may have arisen from the use of formulated feeding pellets. Although the risks of toxicity associated with consumption of red tilapia from the sites investigated were found to be within the tolerable range, the preliminary probabilistic estimation of As cancer risk shows that the 95th percentile risk level surpassed the benchmark level of 10(-5). In general, the probabilistic health risks associated with ingestion of red tilapia can be ranked as follows: former tin mining pool > concrete tank > earthen pond.
    MeSH terms: Animals; Arsenic/analysis; Arsenic/metabolism; Consumer Product Safety; Food Contamination/analysis*; Fresh Water; Humans; Malaysia; Metals/analysis*; Metals/metabolism; Muscles/metabolism; Muscles/chemistry; Water Pollutants, Chemical/analysis*; Water Pollutants, Chemical/metabolism; Tilapia/metabolism*; Seafood/analysis*; Aquaculture; Risk Assessment
  8. Dow RA, Luke SH
    Zootaxa, 2015 Jan 09;3905(1):145-50.
    PMID: 25661028 DOI: 10.11646/zootaxa.3905.1.10
    Phaenandrogomphus safei is described from a male from the Kalabakan Forest Reserve, Sabah, Malaysian Borneo. It is the first species of Phaenandrogomphus to be recorded from Borneo. Onychogomphus treadawayi, known from Busuanga Island in the Palawan region of the Philippines, is transferred to Phaenandrogomphus. 
    MeSH terms: Animals; Animal Structures/anatomy & histology; Animal Structures/growth & development; Borneo; Female; Malaysia; Male; Organ Size; Body Size; Odonata/anatomy & histology; Odonata/classification*; Odonata/growth & development
  9. Chen CA
    Zootaxa, 2015;3905(2):233-44.
    PMID: 25661208 DOI: 10.11646/zootaxa.3905.2.5
    The nematode Pseudoplatycoma malaysianis n. gen. n. sp. is described from the Sulu Sea (Malaysia). The new genus is classified in the subfamily Platycominae Platonova 1976. Revision of the new genus and four other genera in Platycominae, resulted in four species from the genus Platycomopsis being transferred to other genera: P. dimorphica and P. mazjatzavi to the genus Platycoma; P. effilata to the genus Micoletzkyia; and P. gibbonensis to the genus Anticoma. Pilosinema is regarded as a asynonym of Platycomopsis and Platycomopsis paracobbi is regarded as a synonym for P. cobbi. A key for identification of the genera and species of Platycominae is presented. 
    MeSH terms: Animals; Malaysia; Enoplida; Animal Distribution
  10. Dahalan FA, Abdullah N, Yuzir A, Olsson G, Salmiati, Hamdzah M, et al.
    Bioresour Technol, 2015 Apr;181:291-6.
    PMID: 25661308 DOI: 10.1016/j.biortech.2015.01.062
    Aerobic granulation is increasingly used in wastewater treatment due to its unique physical properties and microbial functionalities. Granule size defines the physical properties of granules based on biomass accumulation. This study aims to determine the profile of size development under two physicochemical conditions. Two identical bioreactors namely Rnp and Rp were operated under non-phototrophic and phototrophic conditions, respectively. An illustrative scheme was developed to comprehend the mechanism of size development that delineates the granular size throughout the granulation. Observations on granules' size variation have shown that activated sludge revolutionised into the form of aerobic granules through the increase of biomass concentration in bioreactors which also determined the changes of granule size. Both reactors demonstrated that size transformed in a similar trend when tested with and without illumination. Thus, different types of aerobic granules may increase in size in the same way as recommended in the aerobic granule size development scheme.
    MeSH terms: Aerobiosis; Particle Size*; Sewage/chemistry*; Biomass; Bioreactors; Waste Water
  11. Gunny AA, Arbain D, Nashef EM, Jamal P
    Bioresour Technol, 2015 Apr;181:297-302.
    PMID: 25661309 DOI: 10.1016/j.biortech.2015.01.057
    Deep Eutectic Solvents (DESs) have recently emerged as a new generation of ionic liquids for lignocellulose pretreatment. However, DESs contain salt components which tend to inactivate cellulase in the subsequent saccharification process. To alleviate this problem, it is necessary to evaluate the applicability of the DESs-Cellulase system. This was accomplished in the present study by first studying the stability of cellulase in the presence of selected DESs followed by applicability evaluation based on glucose production, energy consumption and kinetic performance. Results showed that the cellulase was able to retain more than 90% of its original activity in the presence of 10% (v/v) for glycerol based DES (GLY) and ethylene glycol based DES (EG). Furthermore, both DESs system exhibited higher glucose percentage enhancement and lower energy consumption as compared to diluted alkali system. Among the two DESs studied, EG showed comparatively better kinetic performance.
    MeSH terms: Aspergillus/enzymology; Cellulase/metabolism*; Cellulose/chemistry; Enzyme Stability/drug effects; Glucose/analysis; Glycerol/pharmacology; Kinetics; Lignin/metabolism*; Oryza/chemistry; Sodium Hydroxide/pharmacology; Solvents/chemistry*; Waste Products; Ethylene Glycol/pharmacology; Carbohydrate Metabolism/drug effects; Biocatalysis/drug effects
  12. Jałoszyński P
    Zootaxa, 2015;3911(2):273-9.
    PMID: 25661611 DOI: 10.11646/zootaxa.3911.2.8
    Four new species of Cephennomicrus are described from Malaysia: C. curvidens sp. n., C. gentingensis sp. n. (both from the Genting Highlands, West Malaysia), C. santubongensis sp. n. and C. muluensis sp. n. (both from Sarawak, East Malaysia). Male genitalia of all new taxa are illustrated and diagnostic characters are discussed. 
    MeSH terms: Genitalia, Male; Malaysia; Male; Animal Distribution
  13. Ya'cob Z, Takaoka H, Sofian-Azirun M
    Zootaxa, 2015;3911(3):424-32.
    PMID: 25661622 DOI: 10.11646/zootaxa.3911.3.8
    Simulium (Gomphostilbia) hiroyukii is described based on females, males, pupae and larvae collected in Mount Murud, Sarawak, Malaysia. This new species is assigned to the Simulium darjeelingense species-group of the subgenus Gomphostilbia, and is characterized by the darkened fore coxae and the pupal gill with eight long filaments, of which middle and dorsal triplets have elongated primary and secondary stalks, respectively. 
    MeSH terms: Animals; Cytoskeleton; Female; Gills; Larva; Malaysia; Male; Pupa; Simuliidae; Stalking
  14. Seelan JS, Justo A, Nagy LG, Grand EA, Redhead SA, Hibbett D
    Mycologia, 2015 May-Jun;107(3):460-74.
    PMID: 25661717 DOI: 10.3852/14-084
    The genus Lentinus (Polyporaceae, Basidiomycota) is widely documented from tropical and temperate forests and is taxonomically controversial. Here we studied the relationships between Lentinus subg. Lentinus sensu Pegler (i.e. sections Lentinus, Tigrini, Dicholamellatae, Rigidi, Lentodiellum and Pleuroti and polypores that share similar morphological characters). We generated sequences of internal transcribed spacers (ITS) and partial 28S regions of nuc rDNA and genes encoding the largest subunit of RNA polymerase II (RPB1), focusing on Lentinus subg. Lentinus sensu Pegler and the Neofavolus group, combined these data with sequences from GenBank (including RPB2 gene sequences) and performed phylogenetic analyses with maximum likelihood and Bayesian methods. We also evaluated the transition in hymenophore morphology between Lentinus, Neofavolus and related polypores with ancestral state reconstruction. Single-gene phylogenies and phylogenies combining ITS and 28S with RPB1 and RPB2 genes all support existence of a Lentinus/Polyporellus clade and a separate Neofavolus clade. Polyporellus (represented by P. arcularius, P. ciliatus, P. brumalis) forms a clade with species representing Lentinus subg. Lentinus sensu Pegler (1983), excluding L. suavissimus. Lentinus tigrinus appears as the sister group of Polyporellus in the four-gene phylogeny, but this placement was weakly supported. All three multigene analyses and the single-gene analysis using ITS strongly supported Polyporus tricholoma as the sister group of the Lentinus/Polyporellus clade; only the 28S rRNA phylogeny failed to support this placement. Under parsimony the ancestral hymenophoral configuration for the Lentinus/Polyporellus clade is estimated to be circular pores, with independent transitions to angular pores and lamellae. The ancestral state for the Neofavolus clade is estimated to be angular pores, with a single transition to lamellae in L. suavissimus. We propose that Lentinus suavissimus (section Pleuroti) should be reclassified as Neofavolus suavissimus comb. nov.
    MeSH terms: Asia; DNA, Ribosomal/genetics; Fungal Proteins/genetics; Molecular Sequence Data; Phylogeny; Polyporaceae/classification*; Polyporaceae/genetics; Polyporaceae/growth & development; RNA Polymerase II/genetics; RNA, Ribosomal/genetics; Evolution, Molecular*; Lentinula/classification*; Lentinula/genetics; Lentinula/growth & development
  15. Low SF, Sridharan R, Ngiu CS
    BMJ Case Rep, 2015 Feb 06;2015.
    PMID: 25661748 DOI: 10.1136/bcr-2013-202534
    An epidermal cyst is the most common type of cyst to occur in subcutaneous tissue. When its size is greater than 5 cm, it is recognised as a giant epidermal cyst. A subcutaneous giant epidermal cyst with intramuscular extension is extremely rare. The authors report a case of a 74-year-old man who presented with a painless, slow-growing left gluteal mass of 6-month duration. Examination revealed a large left gluteal mass that was fixed to the underlying structures. A small epidermal cyst with visible punctum was noted at the medial aspect of the mass. MRI demonstrated a large, lobulated left gluteal lesion measuring 20 cm×16 cm×10 cm. The lesion was partly within the gluteal maximus muscle and partly within the subcutaneous tissue. MRI and ultrasound features of the lesion were consistent with a giant epidermal cyst with intramuscular extension. The lesion was excised and histology confirmed the diagnosis.
    MeSH terms: Aged; Buttocks; Diagnosis, Differential; Epidermal Cyst/diagnosis*; Humans; Magnetic Resonance Imaging; Male; Muscular Diseases/diagnosis*; Sarcoma/diagnosis; Muscle, Skeletal
  16. Dow RA, Choong CY
    Zootaxa, 2015;3914(1):89-93.
    PMID: 25661930 DOI: 10.11646/zootaxa.3914.1.8
    M. megabinluyog spec. nov. is described from a location in Brunei on the island of Borneo. Additional illustrations of its sister species M. astamii are provided. 
    MeSH terms: Borneo; Brunei; Meridians; Body Size; Islands
  17. Hamid TA, Pakgohar M, Ibrahim R, Dastjerdi MV
    Arch Gerontol Geriatr, 2015 May-Jun;60(3):514-21.
    PMID: 25662038 DOI: 10.1016/j.archger.2015.01.003
    UI is a worldwide chronic condition among postmenopausal women. Little is known about the meaning of lived experiences of urinary incontinence of these women's viewpoints in their context.
    MeSH terms: Aged; Chronic Disease; Female; Humans; Iran/epidemiology; Islam*; Middle Aged; Quality of Life/psychology*; Urinary Incontinence/epidemiology; Urinary Incontinence/psychology*; Prevalence; Postmenopause/psychology*; Hermeneutics*
  18. Asia-Pacific ACS Medical Management Working Group, Huo Y, Thompson P, Buddhari W, Ge J, Harding S, et al.
    Int J Cardiol, 2015 Mar 15;183:63-75.
    PMID: 25662044 DOI: 10.1016/j.ijcard.2014.11.195
    Acute coronary syndromes (ACS) remain a leading cause of mortality and morbidity in the Asia-Pacific (APAC) region. International guidelines advocate invasive procedures in all but low-risk ACS patients; however, a high proportion of ACS patients in the APAC region receive solely medical management due to a combination of unique geographical, socioeconomic, and population-specific barriers. The APAC ACS Medical Management Working Group recently convened to discuss the ACS medical management landscape in the APAC region. Local and international ACS guidelines and the global and APAC clinical evidence-base for medical management of ACS were reviewed. Challenges in the provision of optimal care for these patients were identified and broadly categorized into issues related to (1) accessibility/systems of care, (2) risk stratification, (3) education, (4) optimization of pharmacotherapy, and (5) cost/affordability. While ACS guidelines clearly represent a valuable standard of care, the group concluded that these challenges can be best met by establishing cardiac networks and individual hospital models/clinical pathways taking into account local risk factors (including socioeconomic status), affordability and availability of pharmacotherapies/invasive facilities, and the nature of local healthcare systems. Potential solutions central to the optimization of ACS medical management in the APAC region are outlined with specific recommendations.
    MeSH terms: Asia/epidemiology; Humans; Platelet Aggregation Inhibitors/therapeutic use*; Practice Guidelines as Topic; Oceania/epidemiology; Acute Coronary Syndrome/drug therapy*; Acute Coronary Syndrome/epidemiology*; Acute Coronary Syndrome/surgery; Percutaneous Coronary Intervention
  19. Jałoszyński P
    Zootaxa, 2015;3915(1):143-6.
    PMID: 25662117 DOI: 10.11646/zootaxa.3915.1.9
    A new species of the Oriental genus Elacatophora, E. euconnoides sp. n., is described from the Cameron Highlands, West Malaysia. Diagnostic characters, including the male genitalia, are illustrated and discussed. A new case of subjective synonymy was discovered: Elacatophora minae (Makhan & Ezzatpanah, 2011) is placed as syn. n. of E. soesilae (Makhan & Ezzatpanah, 2011). 
    MeSH terms: Genitalia, Male; Malaysia; Male; Animal Distribution
  20. Kontschán J
    Zootaxa, 2015;3915(1):272-8.
    PMID: 25662124 DOI: 10.11646/zootaxa.3915.2.6
    A new genus Trachyibana gen. nov. is described and illustrated on the basis of Trachyibana sarawakiensis sp. nov. from Malaysia. The new genus belongs to the family Trachyuropodidae, on the basis of its fringed internal malae, the T-shaped dorsal setae and the position of hypostomal setae h3 (lateral to h1-h2-h4). The new genus differs from the other trachyuropodid genera and species by its lemon-shaped idiosoma, the presence of deep opisthogastric ventral furrows, and the absence of strongly sclerotised dorsal structures. 
    MeSH terms: Animals; Citrus; Food Additives; Malaysia; Mites; Sensilla
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