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Evaluation of chemopreventive effects of Acanthus ilicifolius against azoxymethane-induced aberrant Crypt Foci in the rat colon

Almagrami AA 1 , Alshawsh MA 2 , Saif-Ali R 3 , Shwter A 1 , Salem SD 3 , Abdulla MA 1

Affiliations 

  • 1 Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Department of Biochemistry, Faculty of Medicine, Sana'a, Yemen
PLoS One, 2014;9(5):e96004.
PMID: 24819728 DOI: 10.1371/journal.pone.0096004

Abstract

Acanthus ilicifolius, a mangrove medicinal plant, is traditionally used to treat a variety of diseases. The aim of this research is to assess the chemoprotective outcomes of A. ilicifolius ethanolic extract against azoxymethane (AOM) induced colonic aberrant crypt foci (ACF) in rats.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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