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Host genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia

Lu Y 1 , Kham SK 1 , Ariffin H 2 , Oei AM 3 , Lin HP 4 , Tan AM 5 Show all authors , Quah TC 6 , Yeoh AE 6

Affiliations 

  • 1 Division of Haematology-Oncology, Department of Paediatrics, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore
  • 2 1] Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia [2] University of Malaya Cancer Research Institute, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 3 Department of Paediatric Oncology/Haematology, VU University Medical Center, Amsterdam, The Netherlands
  • 4 Department of Paediarics, Sime Darby Medical Centre Subang Jaya, Subang Jaya, Malaysia
  • 5 Department of Paediatric Medicine, Haematology/Oncology Service, KK Women's and Children's Hospital, Singapore, Singapore
  • 6 1] Division of Haematology-Oncology, Department of Paediatrics, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore [2] Viva-University Children's Cancer Centre, University Children's Medical Institute, National University Hospital, Singapore, Singapore [3] National University Cancer Institute Singapore, National University Health System, Singapore
Br. J. Cancer, 2014 Mar 18;110(6):1673-80.
PMID: 24434428 DOI: 10.1038/bjc.2014.7

Abstract

Host germline variations and their potential prognostic importance is an emerging area of interest in paediatric ALL.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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