Affiliations 

  • 1 Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia. kalhasan@ksu.edu.sa
  • 2 Department of Nephrology, Cleveland Clinic Akron General and Akron Children Hospital, Akron, OH, USA
  • 3 Paris Cité University, Pediatric Nephrology, Reference Center for Idiopathic Nephrotic Syndrome in Children and Adults, Imagine Institute, Necker Children's Hospital, APHP, Paris, France
  • 4 Department of Paediatric Nephrology, Starship Children's Hospital, Auckland, New Zealand
  • 5 Department of Pediatrics, University of Puerto Rico-Medical Sciences Campus, San Juan, Puerto Rico
  • 6 Pediatric Nephrology, Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, 122001, Haryana, India
  • 7 Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia
  • 8 Division of Pediatric Nephrology, Department of Pediatrics, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
  • 9 Department of Pediatrics, Faculty of Medicine and Pharmacy, State University of Haïti, State University Hospital of Haïti, Port-Au-Prince, Haiti
  • 10 Department of Primary Care Medicine, Faculty of Medicine, Universiti Malaya, 50603, Kuala Lumpur, Malaysia
  • 11 Department of Pediatric Nephrology, Peking University First Hospital, Beijing, China
  • 12 Children's Institute Hospital das Clinicas Univ Sao Paulo Medical School, Sao Paulo, Brazil
  • 13 Division of Pediatric Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye
  • 14 Department of Pediatric Nephrology, St. John's Medical College Hospital, St. John's Academy of Health Sciences, Bengaluru, India
  • 15 Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa
  • 16 Division of Infectious Diseases and the Transplant and Regenerative Medicine Center, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
  • 17 Department of Paediatrics, Children's Hospital, London Health Science Centre, Western University, 800 Commissioners Road East, London, ON, N6A 5W9, Canada
  • 18 Pediatric Nephrology, Dialysis and Transplant Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy
Pediatr Nephrol, 2025 May;40(5):1795-1815.
PMID: 39733391 DOI: 10.1007/s00467-024-06565-5

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, instigated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has profoundly impacted healthcare infrastructures around the globe. While children are usually asymptomatic or have mild symptoms, children with pre-existing kidney conditions require specialized attention. This pivotal report, championed by the International Pediatric Nephrology Association (IPNA), delivers precise and actionable recommendations tailored for pediatric patients with kidney ailments in this pandemic landscape. Central to our findings are rigorous infection control protocols. These are particularly stringent in high-risk zones, emphasizing telehealth's indispensable role, the significance of curtailing in-person consultations, and the imperative of following rigorous guidelines in regions with heightened COVID-19 prevalence. Additionally, the report delves into vaccination approaches for children with kidney issues, highlighting that the choice of vaccine is often governed by regional accessibility and policy frameworks, rather than a universal preference. A notable observation is the potential correlation between COVID-19 vaccines and specific kidney disorders. However, establishing a direct causal link remains elusive. In summary, our research accentuates the critical need for specialized pediatric kidney care during global health crises and reaffirms the continuous research imperative, especially regarding vaccination ramifications.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.