• 1 Laboratory of Pharmacognosy, Gifu Pharmaceutical University, Gifu Gifu 501-1196, Japan
J Nat Prod, 2010 Sep 24;73(9):1499-506.
PMID: 20735051 DOI: 10.1021/np1002675


Five new stilbenoids, vatalbinosides A-E (1-5), and 13 known compounds (6-18) were isolated from the stem of Vatica albiramis. The effects of these new compounds on interleukin-1β-induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined. Three resveratrol tetramers, (-)-hopeaphenol (6), vaticanol C (13), and stenophyllol C (14), were identified as strong inhibitors of MMP-1 production.

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