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Vancomycin treatment failure in a vancomycin susceptible methicillin-resistant Staphylococcus aureus (MRSA) infected patient

Norazah A 1 , Salbiah N 2 , Nurizzat M 1 , Santhana R 3

Affiliations 

  • 1 Bacteriology Unit, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur
  • 2 Microbiology Unit, Pathology Department, Selayang Hospital, 68100 Batu Caves, Selangor
  • 3 Electron Microscopy Unit, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia
Med J Malaysia, 2009 Jun;64(2):166-7.
PMID: 20058580 MyJurnal

Abstract

A 64-year old patient, who had bacteraemia, did not respond to vancomycin despite the MRSA isolate being sensitive to the antibiotic at MIC 2 microg/mL. Electron microscopy of the MRSA isolate showed thickening of the cell wall, which was not observed in MRSA with lower vancomycin MIC.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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