Study design: A cross-sectional study among health care providers working at one hospital. Objective: To investigate the prevalence, the consequences and the risk factors associated with low back pain (LBP) among hospital staff. Materials and Methods: The study sample consisted of 931 health care providers who answered a pre-established questionnaire including 30 items in two languages. Results: The cumulative life-prevalence of LBP was 72.5% and the yearly prevalence was 56.9%. Chronic LBP prevalence was noted 5.1% of the cases. Treatment was sought in 34.1% of LBP sufferers and 7.3% required sick leave or absence from work due to LBP. Risk factors associated with LBP were professional categories, bad body posture, lifting objects or patients and the increased levels of lifting, levels of job satisfaction and stressful job demands. Conclusion: There was a high prevalence of LBP among hospital staff, resulting in significant medical and socio-professional consequences. Many risk factors were identified that would necessitate multidisciplinary involvement to reduce the LBP incidence and related costs.