Mental health is a growing concern in the field of occupational health globally due to its social, health, and economic implications on the individual and the community at large. As universities in Malaysia are advancing towards becoming world-class research universities, academicians are now faced with more pressures, making them more vulnerable to burnout. A cross sectional study was conducted among 194 randomly sampled academicians from a faculty of a public university. Data was collected using a self-administered questionnaire to assess the sociodemographic characteristics, occupational characteristics and burnout. Analysis was done using SPSS version 21. The response rate was 87.1%. The overall prevalence of burnout was 10.7% with significant associations between gender (χ2 = 4.61; p = 0.03), teaching experience (χ2 = 0.83; p = 0.02), job satisfaction (χ2 = 11.33; p = 0.001). Female academicians have a higher prevalence of burnout (14.3%). Academicians who have fewer years of teaching experience (