Differential Gene Expression of Heat Shock Protein 90 (Hsp90) of Candida albicans obtained from Malaysian and Iranian Patients

Khalili V 1 , Shokri H 2 , Md Akim A 1 , Khosravi AR 3

Affiliations 

  • 1 Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, University of Putra Malaysia, 43400 Serdang, Selangor, Malaysia
  • 2 Department of Pathobiology, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, 24th Aftab, Imam Khomeini Street 46168- 49767, Amol, Iran
  • 3 Mycology Research Center, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Malays J Med Sci, 2016 May;23(3):64-71.
PMID: 27418871

Abstract

Candida albicans (C. albicans) has several virulence factors, in particular heat shock protein 90 (Hsp90), which is expressed by Hsp90 gene. The purposes of this study were to assess the expression of Hsp90 gene in clinical and control isolates of C. albicans obtained from different geographical regions (Malaysia and Iran), different temperatures (25°C, 37°C and 42°C) and mice with candidiasis.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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