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Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma: Case Series

Tang CL 1 , Kumar R 2 , Toh CJ 2 , Azura S 3 , Tan GC 4 , Gendeh BS 1

Affiliations 

  • 1 Department of Otolaryngology, Head and Neck Surgery, University Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Wilayah Persekutuan Kuala Lumpur Malaysia
  • 2 Department of Neurosurgery, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 3 Department of Radiology, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia
  • 4 Department of Histopathology, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Indian J Otolaryngol Head Neck Surg, 2017 Sep;69(3):409-414.
PMID: 28929077 DOI: 10.1007/s12070-015-0909-5

Abstract

Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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