Affiliations 

  • 1 Monash University Malaysia, School of Pharmacy, Novel Bacteria and Drug Discovery (NBDD) Research Group, Selangor Darul Ehsan, Malaysia; Monash University Malaysia, Jeffrey Cheah School of Medicine and Health Sciences, Biomedical Research Laboratory, Selangor Darul Ehsan, Malaysia
  • 2 University of Malaya, Institute of Biological Sciences, Division of Genetics and Molecular Biology, Kuala Lumpur, Malaysia
  • 3 University Kebangsaan Malaysia, UKM Medical Centre, UKM Medical Molecular Biology Institute (UMBI), Kuala Lumpur, Malaysia
  • 4 Monash University Malaysia, School of Pharmacy, Novel Bacteria and Drug Discovery (NBDD) Research Group, Selangor Darul Ehsan, Malaysia; University Kebangsaan Malaysia, UKM Medical Centre, UKM Medical Molecular Biology Institute (UMBI), Kuala Lumpur, Malaysia; University of Phayao, School of Pharmaceutical Sciences, Center of Health Outcomes Research and Therapeutic Safety (Cohorts), Phayao, Thailand
  • 5 Monash University Malaysia, School of Pharmacy, Novel Bacteria and Drug Discovery (NBDD) Research Group, Selangor Darul Ehsan, Malaysia; University Kebangsaan Malaysia, UKM Medical Centre, UKM Medical Molecular Biology Institute (UMBI), Kuala Lumpur, Malaysia; University of Phayao, School of Pharmaceutical Sciences, Center of Health Outcomes Research and Therapeutic Safety (Cohorts), Phayao, Thailand. Electronic address: lee.learn.han@monash.edu
Braz J Microbiol, 2017 09 06;49(1):13-15.
PMID: 28927873 DOI: 10.1016/j.bjm.2017.01.013

Abstract

As the largest genus in Actinobacteria family, Streptomyces species have the ability to synthesize numerous compounds of diverse structures with bioactivities. Streptomyces mangrovisoli MUSC 149T was previously isolated as a novel streptomycete from mangrove forest in east coast of Peninsular Malaysia. The high quality draft genome of MUSC 149T comprises 9,165,825bp with G+C content of 72.5%. Through bioinformatics analysis, 21 gene clusters identified in the genome were associated with the production of bioactive secondary metabolites. The presence of these biosynthetic gene clusters in MUSC 149T suggests the potential exploitation of the strain for production of medically important compounds.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.