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Induction of apoptosis and oxidative stress in estrogen receptor-negative breast cancer, MDA-MB231 cells, by ethanolic mango seed extract

Abdullah AS 1 , Mohammed AS 2 , Rasedee A 3 , Mirghani ME 4 , Al-Qubaisi MS 5

Affiliations 

  • 1 Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. al-shwyeh-hussah@hotmail.com
  • 2 Faculty of Food Science and Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. karimsabo@upm.edu.my
  • 3 Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. rasedee@upm.edu.my
  • 4 Department of Biotechnology Engineering Faculty of Engineering, International Islamic University Malaysia (IIUM), P.O. BOX 10, 50728, Kuala Lumpur, Malaysia. elwathig@iium.edu.my
  • 5 Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. mothannasobk@yahoo.com
BMC Complement Altern Med, 2015;15:45.
PMID: 25881293 DOI: 10.1186/s12906-015-0575-x

Abstract

In this study, the effect of mango kernel extract in the induction of apoptosis of the breast cancer (MDA-MB-231) cell line was examined. This is an attempt to discover alternatives to current therapeutic regimes in the treatment of breast cancers.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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