Affiliations 

  • 1 Centre of Advanced Materials (CAM), Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: katayoon@um.edu.my
  • 2 Centre of Advanced Materials (CAM), Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • 3 Department of Chemical Engineering, 313 Snell Engineering Center, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA
Carbohydr Polym, 2019 Mar 01;207:588-600.
PMID: 30600043 DOI: 10.1016/j.carbpol.2018.12.011

Abstract

This review outlines new developments in the biomedical applications of environmentally friendly ('green') chitosan and chitosan-blend electrospun nanofibers. In recent years, research in functionalized nanofibers has contributed to the development of new drug delivery systems and improved scaffolds for regenerative medicine, which is currently one of the most rapidly growing fields in all of the life sciences. Chitosan is a biopolymer with non-toxic, antibacterial, biodegradable and biocompatible properties. Due to these properties, they are widely applied for biomedical applications such as drug delivery, tissue engineering scaffolds, wound dressings, and antibacterial coatings. Electrospinning is a novel technique for chitosan nanofiber fabrication. These nanofibers can be used in unique applications in biomedical fields due to their high surface area and porosity. The present work reviews recent reports on the biomedical applications of chitosan-based nanofibers in detail.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.