Zinc supplementation influences genomic stability biomarkers, antioxidant activity, and zinc transporter genes in an elderly Australian population with low zinc status

Sharif R 1 , Thomas P 2 , Zalewski P 3 , Fenech M 2

Affiliations 

  • 1 Program of Nutritional Sciences, School of HealthCare Sciences, Faculty of Health Science, Universiti Kebangsaan Malaysia, Malaysia
  • 2 CSIRO Food and Nutrition, Adelaide, South Australia, Australia
  • 3 School of Medicine, Faculty of Health Sciences, University of Adelaide, South Australia, Australia
Mol Nutr Food Res, 2015 Jun;59(6):1200-12.
PMID: 25755079 DOI: 10.1002/mnfr.201400784

Abstract

An increased intake of Zinc (Zn) may reduce the risk of degenerative diseases but may prove to be toxic if taken in excess. This study aimed to investigate whether zinc carnosine supplement can improve Zn status, genome stability events, and Zn transporter gene expression in an elderly (65-85 years) South Australian cohort with low plasma Zn levels.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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