Small longitudinal study of serum anticholinergic activity and cognitive change in community-dwelling older adults

Kashyap M 1 , Mulsant BH 2 , Tannenbaum C 3

Affiliations 

  • 1 Faculty of Pharmacy, AIMST University, Semeling, Malaysia. Electronic address: avi_mandu@yahoo.co.in
  • 2 Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
  • 3 Departments of Medicine and Pharmacy, Université; de Montréal, Centre de Recherche, Institut Universitaire de Gériatrie de Montréal, Montreal, Quebec, Canada
Am J Geriatr Psychiatry, 2015 Mar;23(3):326-9.
PMID: 25450763 DOI: 10.1016/j.jagp.2014.09.009

Abstract

The discriminative ability of serum anticholinergic activity (SAA) to differentiate between older individuals with stable versus deteriorating cognition remains undetermined. We examined the relationship between SAA changes, the presence or absence of a mild neurocognitive disorder, age and anticholinergic medication over a one-year time period.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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