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Hypertension and stroke in Asia: A comprehensive review from HOPE Asia

Turana Y 1 , Tengkawan J 1 , Chia YC 2 , Nathaniel M 1 , Wang JG 3 , Sukonthasarn A 4 Show all authors , Chen CH 5 , Minh HV 6 , Buranakitjaroen P 7 , Shin J 8 , Siddique S 9 , Nailes JM 10 , Park S 11 , Teo BW 12 , Sison J 13 , Ann Soenarta A 14 , Hoshide S 15 , Tay JC 16 , Prasad Sogunuru G 17 , Zhang Y 18 , Verma N 19 , Wang TD 20 , Kario K 15 , HOPE Asia Network

Affiliations 

  • 1 School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • 2 Department of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Bandar Sunway, Malaysia
  • 3 Department of Hypertension, Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
  • 4 Cardiology Division, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • 5 Department of Medicine, Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan
  • 6 Department of Cardiology, Hue University Hospital, Hue University, Hue City, Vietnam
  • 7 Division of Hypertension, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • 8 Faculty of Cardiology Service, Hanyang University Medical Center, Seoul, Korea
  • 9 Punjab Medical Center, Lahore, Pakistan
  • 10 University of the East Ramon Magsaysay Memorial Medical Center Inc., Quezon City, Philippines
  • 11 Division of Cardiology, Cardiovascular Hospital, Yonsei Health System, Seoul, Korea
  • 12 Division of Nephrology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore
  • 13 Section of Cardiology, Department of Medicine, Medical Center Manila, Manila, Philippines
  • 14 Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia-National Cardiovascular Center, Harapan Kita, Jakarta, Indonesia
  • 15 Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan
  • 16 Department of General Medicine, Tan Tock Seng Hospital, Singapore, Singapore
  • 17 MIOT International Hospital, Chennai, India
  • 18 Divisions of Hypertension and Heart Failure, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  • 19 Department of Physiology, King George's Medical University, Lucknow, India
  • 20 Cardiovascular Center and Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei City, Taiwan
J Clin Hypertens (Greenwich), 2021 Mar;23(3):513-521.
PMID: 33190399 DOI: 10.1111/jch.14099

Abstract

Stroke is the primary cause of disability and vascular death worldwide, including Asia. Asian characteristics that differ from the West lead to higher stroke incidence. Stroke epidemiology studies in Asia have shown varying levels of mortality, incidence, prevalence, and burden of disease. Hypertension is the most prevalent risk factor found in Asia. Besides ethnicity that is associated with stroke incidence, both systolic blood pressure, diastolic blood pressure, and blood pressure variability are positively correlated with stroke incidence. Post-stroke cognitive impairment is one of the sequelae that affect one-third of stroke survivors and has become a significant public health concern that is often neglected despite its increasing prevalence. Therefore, it is very important to prevent recurrence by treating stroke optimally and effectively. Increasing awareness and treatment adherence to hypertension, the leading risk factor for stroke, became the main goal in several countries in Asia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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