Affiliations 

  • 1 Department of Pharmacy, Punjab University College of Pharmacy, AllamaIqbal Campus, University of the Punjab, 54000, Lahore, Pakistan. Electronic address: msnawaz@bs.qau.edu.pk
  • 2 Saulat Institute of Pharmaceutical Sciences & Drug Research, Quaid-i-Azam University, Islamabad, Pakistan
  • 3 District Head Quarter (DHQ) Hospital, Pakpattan and Punjab University Lahore, Pakistan
  • 4 School of Pharmacy, Monash University, Jalan Lagoon Selatan, 47500, Bandar Sunway Selangor DarulEhsan, Malaysia
  • 5 Capital Authority Hospital Islamabad, Pakistan
  • 6 Institute of Pharmaceutical Sciences, University of Veterinary and Animal Science, Lahore, Pakistan
Diabetes Metab Syndr, 2021 Feb 13;15(2):525-528.
PMID: 33668002 DOI: 10.1016/j.dsx.2021.02.013

Abstract

BACKGROUND AND AIMS: Restless legs syndromes (RLS) are intrinsic sleeping disorder and its prevalence rate is 10-15% in general population but it is observed that prevalence rate is different in diabetes patients. Current study aims to find prevalence and determinants of RLS in people living with type 2 diabetes mellitus in Pakistan.

METHOD: A multicenter cross-sectional observational study was conducted in 388 diabetes patients attending daily diabetes clinics and teaching hospitals in Pakistan's twin city between August 2019 and February 2020. The chi-square test and linear regression were used to detect RLS-related factors in type 2 diabetes mellitus.

RESULTS: The prevalence of RLS found was; 3.1% patients with diabetes were suffering from very severe RLS, 23.5% from severe RLS, 34% from moderate RLS, 21.1% from mild RLS and 18.3% from non-RLS. Gender, age, education, blood glucose fasting (BSF), blood glucose random (BSR) and HBA1c were found to be significant predictors of RLS in patients with diabetes.

CONCLUSION: Policy makers can develop local interventions to curb the growing RLS prevalence by keeping in control the risk factors of RLS in people living with type 2 diabetes.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.