Displaying publications 1 - 20 of 101 in total

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  1. Fulltext A Patient with Beta-Propeller Protein-Associated Neurodegeneration: Treatment with Iron Chelation Therapy
    Lim SY, Tan AH, Ahmad-Annuar A, Schneider SA, Bee PC, Lim JL, et al.
    J Mov Disord, 2018 May;11(2):89-92.
    PMID: 29860786 DOI: 10.14802/jmd.17082
    We present a case of beta-propeller protein-associated neurodegeneration, a form of neurodegeneration with brain iron accumulation. The patient harbored a novel mutation in the WDR45 gene. A detailed video and description of her clinical condition are provided. Her movement disorder phenomenology was characterized primarily by limb stereotypies and gait dyspraxia. The patient's disability was advanced by the time iron-chelating therapy with deferiprone was initiated, and no clinical response in terms of cognitive function, behavior, speech, or movements were observed after one year of treatment.
    Matched MeSH terms: Gait Apraxia
  2. Fulltext A comparative study between self-perception of walking ability, balance and risk of fall with actual clinical assessment
    Nurulaini, A., Syahnaz, M.H., Shamsul, A.S., Teh Rohaila, J.
    Medicine & Health, 2018;13(2):133-144.
    MyJurnal
    Gait and balance disorder are among the most common causes of falls in elderly and often lead to injury, disability and loss of independence. However, there might be a discrepancy between elderly’s perception of their own walking ability, balance, risk of fall with doctor’s evaluation. The aim of this study was to compare perception of the elderly’s walking ability, balance and risk of fall with clinical assessment. This cross sectional study was done in a Primary Care Clinic which involved elderly > 60 years using systematic random sampling. Participants completed a self-administered questionnaire comprising of sociodemographic data and question assessing their perception of ability of walking, balance and risk of fall. Actual clinical assessment was done using Tinetti Performance Oriented Mobility Assessment. Most of the participants perceived they had good walking (84.4%) and balance ability (77%). A small proportion (11.5%) agreed that they are at risk of fall. There was a good agreement in walking ability (k: 0.702, p:
    Matched MeSH terms: Gait
  3. A computational method for reliable gait event detection and abnormality detection for feedback in rehabilitation
    Senanayake C, Senanayake SM
    Comput Methods Biomech Biomed Engin, 2011 Oct;14(10):863-74.
    PMID: 20924859 DOI: 10.1080/10255842.2010.499866
    In this paper, a gait event detection algorithm is presented that uses computer intelligence (fuzzy logic) to identify seven gait phases in walking gait. Two inertial measurement units and four force-sensitive resistors were used to obtain knee angle and foot pressure patterns, respectively. Fuzzy logic is used to address the complexity in distinguishing gait phases based on discrete events. A novel application of the seven-dimensional vector analysis method to estimate the amount of abnormalities detected was also investigated based on the two gait parameters. Experiments were carried out to validate the application of the two proposed algorithms to provide accurate feedback in rehabilitation. The algorithm responses were tested for two cases, normal and abnormal gait. The large amount of data required for reliable gait-phase detection necessitate the utilisation of computer methods to store and manage the data. Therefore, a database management system and an interactive graphical user interface were developed for the utilisation of the overall system in a clinical environment.
    Matched MeSH terms: Gait*
  4. Fulltext A man with febrile illness and difficulty in walking
    Das Gupta E
    Malays Fam Physician, 2008;3(1):51.
    PMID: 25606113
    Matched MeSH terms: Gait Disorders, Neurologic
  5. Fulltext A preliminary evaluation of linear control schemes for FES-assisted movements
    Ahmed, M., Huq, M.S., Ibrahim, B.S.K.K., Ahmed, A.
    Movement Health & Exercise, 2018;7(1):211-223.
    MyJurnal
    Functional Electrical Stimulation (FES) can be used to revive movement
    functions of the human body to a certain degree which was lost due to
    occurrences of the nervous system disorders resulting from accidents or
    diseases. It can also be employed for gait rehabilitation as well as therapy.
    Control systems could be employed to improve on the FES-induced motion,
    and the closed-loop was targeted due to its advantages. Based on the papers
    reviewed, studies have shown that the linear control schemes are popular for
    movement restoration in the lower limb, but mostly for continuous standing
    contributing to mainly the stance phase. Therefore, a myriad of limitations
    was observed which include: the need for using improved sensors, re-tuning
    for every subject, tests conducted using patient with more straightforward
    ailments, complexity in implementation and most importantly is the issue of
    stability. The swing phase of gait movement and the full walking motion have
    more complex dynamics and coupled with the nature of the plant (human with
    nervous system disorder and the neuromuscular structure) could render the
    linear control method obsolete or unsuitable. Hence, there is a need to
    investigate other techniques such as the nonlinear and intelligent control
    methods.
    Matched MeSH terms: Gait
  6. A robust real-time gait event detection using wireless gyroscope and its application on normal and altered gaits
    Gouwanda D, Gopalai AA
    Med Eng Phys, 2015 Feb;37(2):219-25.
    PMID: 25619613 DOI: 10.1016/j.medengphy.2014.12.004
    Gait events detection allows clinicians and biomechanics researchers to determine timing of gait events, to estimate duration of stance phase and swing phase and to segment gait data. It also aids biomedical engineers to improve the design of orthoses and FES (functional electrical stimulation) systems. In recent years, researchers have resorted to using gyroscopes to determine heel-strike (HS) and toe-off (TO) events in gait cycles. However, these methods are subjected to significant delays when implemented in real-time gait monitoring devices, orthoses, and FES systems. Therefore, the work presented in this paper proposes a method that addresses these delays, to ensure real-time gait event detection. The proposed algorithm combines the use of heuristics and zero-crossing method to identify HS and TO. Experiments involving: (1) normal walking; (2) walking with knee brace; and (3) walking with ankle brace for overground walking and treadmill walking were designed to verify and validate the identified HS and TO. The performance of the proposed method was compared against the established gait detection algorithms. It was observed that the proposed method produced detection rate that was comparable to earlier reported methods and recorded reduced time delays, at an average of 100 ms.
    Matched MeSH terms: Gait*
  7. A state-of-the-art review of foot pressure
    Zulkifli SS, Loh WP
    Foot Ankle Surg, 2020 Jan;26(1):25-32.
    PMID: 30600155 DOI: 10.1016/j.fas.2018.12.005
    The science of foot pressure studies the forces acting on the bottom and different regions of the foot along with the pressure exerted on the plantar surface with the interacting surface in contact. The information derived gave impact to human biomechanical assessment on body balance and ergonomics posture during gait. Various experiments designed at generating foot pressure data returns only with limited knowledge generated. Obviously, the procedure for experiment design needs to be properly understood from the foot morphology aspects; healthiness, footwear, surface in contact, load and forces impacts, and the foot sensitivity as well as the specification for the foot pressure. This paper reviews the proper preliminary experimental setups for foot pressure measurement analysis during static or dynamic gait. The strength and limitations of recent devices used and considerable variables are also discussed. The overall review explains that the comfortable natural gait in relation to the aspects of sensitivity, load, time duration, and stability are the standard considerations for plantar pressure experiments.
    Matched MeSH terms: Gait/physiology*
  8. A study on body movement analysis by the foot slip pattern in a fall
    Kim SH, Kim DW
    Sains Malaysiana, 2015;44:1745-1750.
    A fracture, which mostly results from a fall, is fatal for the elderly. A fall occurred when a person cannot maintain the
    body position. Most falls occurred when a person walks on a slippery surface or trips over an object on the ground during
    a gait. Most people try to avoid falls instinctively and fall when their attempt fails. As such, this study investigated the
    difference between two movements- a movement to avoid falls and a forward-falling movement without a fall-avoiding
    movement- by analyzing the body movements of the subjects. A fast-moving fall-guiding device with a pneumatic actuator
    was used to guide falls. The movement of the device could simulate a foot slip that may happen during daily activities.
    A three-axis acceleration sensor and a Bluetooth module were used to avoid disturbing the body movement during a fall
    as a wire sensor or a movement analysis system does.
    Matched MeSH terms: Gait
  9. A triple compound pendulum model to analyse the effect of an ankle-foot orthosis on swing phase kinematics
    Marconi G, Gopalai AA, Chauhan S
    Med Eng Phys, 2023 Feb;112:103951.
    PMID: 36842774 DOI: 10.1016/j.medengphy.2023.103951
    Powered ankle-foot orthoses can be utilised to overcome gait abnormalities such as foot drop; however, normal gait is rarely restored with compensatory gait patterns arising and prevalence of gait asymmetry. Therefore, this study aims to determine the effect of orthosis mass and mass distribution on the swing phase of gait, to understand residual gait asymmetry with orthosis use. Using a triple compound pendulum model, which accounts for mass distribution of the limb and orthosis, the swing phase of gait is simulated in terms of natural dynamics and the effect of an orthosis on kinematic parameters is quantitatively determined. It was found that additional mass causes faster and shorter steps on the affected side due to rapid knee extension and reduced hip flexion, with particular actuator positions and natural cadence causing varying severity of these effects. Our study suggests that this model could be used as a preliminary design tool to identify subject specific optimum orthosis mass distribution of a powered ankle-foot orthosis, without the need for motion data or experimental trials. This optimisation intends to more accurately mimic natural swing phase kinematics, consequently allowing for the reduction in severity of gait asymmetry and the potential to improve rehabilitative outcomes.
    Matched MeSH terms: Gait
  10. Acute necrotising encephalopathy of childhood: A review of two cases
    Ong SCL, Nur Azidawati AH, Liew YH, Anita S
    Med J Malaysia, 2017 10;72(5):311-313.
    PMID: 29197889 MyJurnal
    Acute necrotising encephalopathy of childhood (ANEC) is an uncommon disease with characteristic clinical and imaging findings. We present two cases of ANEC secondary to Respiratory Syncytial Virus (RSV) and mycoplasma infections. An eight-month-old boy presented with features of gastroenteritis but soon developed multiple episodes of seizures. Blood and CSF cultures were negative but nasopharyngeal aspirate immunofluorescence was positive for RSV. A nine-year-old girl presented with abnormal behaviour following two days of prodromal symptoms. Her serological markers implicated mycoplasma (IgM titre 1: 640). CT brain of both patients showed bilateral symmetrical thalamic hypodensities, while MRI revealed more extensive white matter involvements.
    Matched MeSH terms: Gait Disorders, Neurologic
  11. Aerial and Terrestrial Patterns: A Novel Approach to Analyzing Human Running
    Gindre C, Lussiana T, Hebert-Losier K, Mourot L
    Int J Sports Med, 2016 Jan;37(1):25-9.
    PMID: 26509380 DOI: 10.1055/s-0035-1555931
    Biomechanical parameters are often analyzed independently, although running gait is a dynamic system wherein changes in one parameter are likely to affect another. Accordingly, the Volodalen® method provides a model for classifying running patterns into 2 categories, aerial and terrestrial, using a global subjective rating scoring system. We aimed to validate the Volodalen® method by verifying whether the aerial and terrestrial patterns, defined subjectively by a running coach, were associated with distinct objectively-measured biomechanical parameters. The running patterns of 91 individuals were assessed subjectively using the Volodalen® method by an expert running coach during a 10-min running warm-up. Biomechanical parameters were measured objectively using the OptojumpNext® during a 50-m run performed at 3.3, 4.2, and 5 m·s(-1) and were compared between aerial- and terrestrial-classified subjects. Longer contact times and greater leg compression were observed in the terrestrial compared to the aerial runners. The aerial runners exhibited longer flight time, greater center of mass displacement, maximum vertical force and leg stiffness than the terrestrial ones. The subjective categorization of running patterns was associated with distinct objectively-quantified biomechanical parameters. Our results suggest that a subjective holistic assessment of running patterns provides insight into the biomechanics of running gaits of individuals.
    Matched MeSH terms: Gait/physiology*
  12. Fulltext An Englishman with Progressive Deterioration in Cognitive Function
    Hamidon, B.B., Sapiah, S.
    International Medical Journal Malaysia, 2006;5(1):1-6.
    MyJurnal
    A 72-year old Englishman was admitted with rapid deterioration in cognitive function, gait disturbance, and cerebellar signs and lapsed into a coma within one week of admission to the hospital. He had long-standing hypertension and hypercholesterolaemia, for which he was on regular medication. He had suffered recurrent episodes of stroke between September 1997 and May 2001. Three months prior to presentation, he became forgetful and generally mentally slow, affecting his daily activities. He was also noted to have fluctuations in his conscious level, associated with myoclonic jerks of the limbs. The brain MRI revealed hyperintense lesions on T2- weighted images in the periventricular region, left corona radiata, centrum semiovale, pons, midbrain and right thalamus. The electroencephalograph revealed periodic sharp wave complexes, strongly suggestive of Creutzfeldt-Jakob disease. However, we were not able to get a tissue diagnosis or send the cerebrospinal fluid for protein 14-3-3.
    Matched MeSH terms: Gait
  13. An experimental study of the interface pressure profile during level walking of a new suspension system for lower limb amputees
    Eshraghi A, Abu Osman NA, Gholizadeh H, Ali S, Sævarsson SK, Wan Abas WA
    Clin Biomech (Bristol, Avon), 2013 Jan;28(1):55-60.
    PMID: 23157843 DOI: 10.1016/j.clinbiomech.2012.10.002
    Different suspension systems that are used within prosthetic devices may alter the distribution of pressure inside the prosthetic socket in lower limb amputees. This study aimed to compare the interface pressure of a new magnetic suspension system with the pin/lock and Seal-In suspension systems.
    Matched MeSH terms: Gait*
  14. Are the spatio-temporal parameters of gait capable of distinguishing a faller from a non-faller elderly?
    Mortaza N, Abu Osman NA, Mehdikhani N
    Eur J Phys Rehabil Med, 2014 Dec;50(6):677-91.
    PMID: 24831570
    Fall is a common and a major cause of injuries. It is important to find elderlies who are prone to falls. The majority of serious falls occur during walking among the older adults. Analyzing the spatio-temporal parameters of walking is an easy way of assessment in the clinical setting, but is it capable of distinguishing a faller from a non-faller elderly? Through a systematic review of the literature, the objective of this systematic review was to identify and summarize the differences in the spatio-temporal parameters of walking in elderly fallers and non-fallers and to find out if these parameters are capable of distinguishing a faller from a non-faller. All original research articles which compared any special or temporal walking parameters in faller and non-faller elderlies were systematically searched within the Scopus and Embase databases. Effect size analysis was also done to standardize findings and compare the gait parameters of fallers and non-fallers across the selected studies. The electronic search led to 5381 articles. After title and abstract screening 30 articles were chosen; further assessment of the full texts led to 17 eligible articles for inclusion in the review. It seems that temporal measurements are more sensitive to the detection of risk of fall in elderly people. The results of the 17 selected studies showed that fallers have a tendency toward a slower walking speed and cadence, longer stride time, and double support duration. Also, fallers showed shorter stride and step length, wider step width and more variability in spatio-temporal parameters of gait. According to the effect size analysis, step length, gait speed, stride length and stance time variability were respectively more capable of differentiating faller from non-faller elderlies. However, because of the difference of methodology and number of studies which investigated each parameter, these results are prone to imprecision. Spatio-temporal analysis of level walking is not sufficient and cannot act as a reliable predictor of falls in elderly individuals.
    Matched MeSH terms: Gait/physiology*
  15. Assessment of Gait Symmetry Improvements in National Athletes after Anterior Cruciate Ligament Reconstruction during Rehabilitation
    Hadizadeh M, Amri S, Roohi SA, Mohafez H
    Int J Sports Med, 2016 Nov;37(12):997-1002.
    PMID: 27551935
    This study aimed to quantify changes in gait parameters and their symmetries among athletes with anterior cruciate ligament (ACL) reconstructions during a rehabilitation program. Twenty-two national players with ACL reconstructions and 15 healthy athletes were recruited. The gait data were collected between postoperative weeks 4-5, 8-9 and 12-13 using a three-dimensional motion analysis system. The spatio-temporal gait parameters and symmetry indexes (SIs) were evaluated for the patients and the control group. One-way and repeated-measures multivariate analysis of variance were used to analyse the data. The results demonstrated significant differences among spatio-temporal (P<0.001) and SIs (P=0.007) of patients for Test 1 and the control group. Repeated measure analysis revealed significant changes in the linear combinations of spatio-temporal gait variables (P=0.002) and SIs (P=0.043) over time. The injured limb's step length, cadence and weight acceptance time presented significant improvement across time (P<0.001). Moreover, the SI of the stance time was reduced significantly by 46.48% (P=0.004) among SI parameters. After three months, no significant differences were found between patients and healthy controls for the measured gait components (P>0.05). The rehabilitation program allowed national athletes to restore symmetry in spatio-temporal gait parameters toward the control group's range 12-13 weeks post-reconstruction.
    Matched MeSH terms: Gait/physiology*
  16. Fulltext Association between Lameness and Indicators of Dairy Cow Welfare Based on Locomotion Scoring, Body and Hock Condition, Leg Hygiene and Lying Behavior
    B Sadiq M, Ramanoon SZ, Shaik Mossadeq WM, Mansor R, Syed-Hussain SS
    Animals (Basel), 2017 Nov 05;7(11).
    PMID: 29113033 DOI: 10.3390/ani7110079
    Dairy cow welfare is an important consideration for optimal production in the dairy industry. Lameness affects the welfare of dairy herds by limiting productivity. Whilst the application of LS systems helps in identifying lame cows, the technique meets with certain constraints, ranging from the detection of mild gait changes to on-farm practical applications. Recent studies have shown that certain animal-based measures considered in welfare assessment, such as body condition, hock condition and leg hygiene, are associated with lameness in dairy cows. Furthermore, behavioural changes inherent in lame cows, especially the comfort in resting and lying down, have been shown to be vital indicators of cow welfare. Highlighting the relationship between lameness and these welfare indicators could assist in better understanding their role, either as risk factors or as consequences of lameness. Nevertheless, since the conditions predisposing a cow to lameness are multifaceted, it is vital to cite the factors that could influence the on-farm practical application of such welfare indicators in lameness studies. This review begins with the welfare consequences of lameness by comparing normal and abnormal gait as well as the use of LS system in detecting lame cows. Animal-based measures related to cow welfare and links with changes in locomotion as employed in lameness research are discussed. Finally, alterations in lying behaviour are also presented as indicators of lameness with the corresponding welfare implication in lame cows.
    Matched MeSH terms: Gait
  17. Fulltext Atypical Presentation of Takotsubo Cardiomyopathy: Stroke as a Predisposing Factor
    Loong CW, Firdaus MAM, Said MRM, Abidin IZ
    Medeni Med J, 2020;35(3):266-270.
    PMID: 33110680 DOI: 10.5222/MMJ.2020.47374
    Takotsubo syndrome is a rare disease and remained ambiguous with its etiology. The disease manifests in various clinical characteristics and even mimicking acute coronary syndrome. We are reporting a case of an elderly lady who manifested by unsteady gaits and recurrent falls. Subacute infarct of the right corona radiata was observed on the brain CT. In addition, coronary angiography and ventriculogram were performed because of dynamic ECG changes and elevated troponin I levels. The angiogram was normal while ventriculogram showed apical ballooning. She was diagnosed and treated as Takotsubo syndrome.
    Matched MeSH terms: Gait
  18. Fulltext Automated Gait Analysis Based on a Marker-Free Pose Estimation Model
    Hii CST, Gan KB, Zainal N, Mohamed Ibrahim N, Azmin S, Mat Desa SH, et al.
    Sensors (Basel), 2023 Jul 18;23(14).
    PMID: 37514783 DOI: 10.3390/s23146489
    Gait analysis is an essential tool for detecting biomechanical irregularities, designing personalized rehabilitation plans, and enhancing athletic performance. Currently, gait assessment depends on either visual observation, which lacks consistency between raters and requires clinical expertise, or instrumented evaluation, which is costly, invasive, time-consuming, and requires specialized equipment and trained personnel. Markerless gait analysis using 2D pose estimation techniques has emerged as a potential solution, but it still requires significant computational resources and human involvement, making it challenging to use. This research proposes an automated method for temporal gait analysis that employs the MediaPipe Pose, a low-computational-resource pose estimation model. The study validated this approach against the Vicon motion capture system to evaluate its reliability. The findings reveal that this approach demonstrates good (ICC(2,1) > 0.75) to excellent (ICC(2,1) > 0.90) agreement in all temporal gait parameters except for double support time (right leg switched to left leg) and swing time (right), which only exhibit a moderate (ICC(2,1) > 0.50) agreement. Additionally, this approach produces temporal gait parameters with low mean absolute error. It will be useful in monitoring changes in gait and evaluating the effectiveness of interventions such as rehabilitation or training programs in the community.
    Matched MeSH terms: Gait*
  19. Axial Segmental Coordination During Turning: Effects of Stroke and Attentional Loadings
    Manaf H, Justine M, Goh HT
    Motor Control, 2017 Jan;21(1):42-57.
    PMID: 26595318 DOI: 10.1123/mc.2015-0040
    Attentional loadings deteriorate straight walking performance for individuals poststroke, but its effects on turning while walking remain to be determined. Here we compared turning kinematics under three attentional loading conditions (single, dual-motor, and dual-cognitive task) between stroke survivors and healthy controls. Nine chronic stroke survivors and 10 healthy controls performed the Timed Upand- Go test while their full-body kinematics were recorded. Onset times of yaw rotation of the head, thorax and pelvis segments and head anticipation distance were used to quantify turning coordination. Results showed that stroke survivors reoriented their body segments much earlier than the controls, but they preserved the similar segmental reorientation sequence under the single-task condition. For the healthy controls, attentional loading led to an earlier axial segment reorientation, but the reorientation sequence was preserved. In contrast, the dual-cognitive task condition led to a disrupted reorientation sequence in stroke. The results indicate that turning coordination was altered in individuals poststroke, especially under the dual-task interference.
    Matched MeSH terms: Gait
  20. Biomechanical and functional efficacy of knee sleeves: A literature review
    Mohd Sharif NA, Goh SL, Usman J, Wan Safwani WKZ
    Phys Ther Sport, 2017 Nov;28:44-52.
    PMID: 28673759 DOI: 10.1016/j.ptsp.2017.05.001
    BACKGROUND: Knee sleeves are widely used for the symptomatic relief and subjective improvements of knee problems. To date, however, their biomechanical effects have not been well understood.

    OBJECTIVE: To determine whether knee sleeves can significantly improve the biomechanical variables for knee problems.

    METHOD: Systematic literature search was conducted on four online databases - PubMed, Web of Science, ScienceDirect and Springer Link - to find peer-reviewed and relevant scientific papers on knee sleeves published from January 2005 to January 2015. Study quality was assessed using the Structured Effectiveness Quality Evaluation Scale (SEQES).

    RESULTS: Twenty studies on knee sleeves usage identified from the search were included in the review because of their heterogeneous scope of coverage. Twelve studies found significant improvement in gait parameters (3) and functional parameters (9), while eight studies did not find any significant effects of knee sleeves usage.

    CONCLUSION: Most improvements were observed in: proprioception for healthy knees, gait and balance for osteoarthritic knees, and functional improvement of injured knees. This review suggests that knee sleeves can effect functional improvements to knee problems. However, further work is needed to confirm this hypothesis, due to the lack of homogeneity and rigor of existing studies.

    Matched MeSH terms: Gait
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