MyMedR

Fulltext Bertolotti's syndrome: A commonly missed cause of back pain in young patients

Manmohan S, Dzulkarnain A, Nor Azlin ZA, Fazir M

Malays Fam Physician, 2015;10(2):55-8.

Bertolotti's syndrome must be considered as a differential diagnosis for lower back pain in young people. Treatment, whether conservative or operative, is still debatable. In this paper, we report a case of a 20-year-old girl presenting with lower back pain for 8 years. We administered injection with local anaesthetic and steroid injections within the pseudo-articulation; however, the pain was relieved for 3 weeks. Surgical excision of the pseudo-articulation successfully treated her back pain and the sciatica.

Matched MeSH terms: Female

Ureteroscopy: the first line treatment for distal located ureteral stones smaller than 10 mm

Kamarulzaman MN

Urol J, 2014 Nov 01;11(5):1914.

PMID: 25361715

Matched MeSH terms: Female

Fulltext Heterozygosity-fitness correlations in a wild mammal population: accounting for parental and environmental effects

Annavi G, Newman C, Buesching CD, Macdonald DW, Burke T, Dugdale HL

Ecol Evol, 2014 Jun;4(12):2594-609.

PMID: 25360289 DOI: 10.1002/ece3.1112

HFCs (heterozygosity-fitness correlations) measure the direct relationship between an individual's genetic diversity and fitness. The effects of parental heterozygosity and the environment on HFCs are currently under-researched. We investigated these in a high-density U.K. population of European badgers (Meles meles), using a multimodel capture-mark-recapture framework and 35 microsatellite loci. We detected interannual variation in first-year, but not adult, survival probability. Adult females had higher annual survival probabilities than adult males. Cubs with more heterozygous fathers had higher first-year survival, but only in wetter summers; there was no relationship with individual or maternal heterozygosity. Moist soil conditions enhance badger food supply (earthworms), improving survival. In dryer years, higher indiscriminate mortality rates appear to mask differential heterozygosity-related survival effects. This paternal interaction was significant in the most supported model; however, the model-averaged estimate had a relative importance of 0.50 and overlapped zero slightly. First-year survival probabilities were not correlated with the inbreeding coefficient (f); however, small sample sizes limited the power to detect inbreeding depression. Correlations between individual heterozygosity and inbreeding were weak, in line with published meta-analyses showing that HFCs tend to be weak. We found support for general rather than local heterozygosity effects on first-year survival probability, and g2 indicated that our markers had power to detect inbreeding. We emphasize the importance of assessing how environmental stressors can influence the magnitude and direction of HFCs and of considering how parental genetic diversity can affect fitness-related traits, which could play an important role in the evolution of mate choice.

Matched MeSH terms: Female

The role of chunking in drawing Rey complex figure

Obaidellah UH, Cheng PC

Percept Mot Skills, 2015 Apr;120(2):535-55.

PMID: 25706345 DOI: 10.2466/24.PMS.120v17x6

The study investigated the effects of chunking and perceptual patterns that guide the drawings of Rey complex figure. Ten adult participants (M age=22.2 yr., SD=4.1) reproduced a single stimulus in four drawing modes including delayed recall, tracing, copying, and immediate recall across 10 sessions producing a total of 400 trials. It was hypothesized that the effect of chunking is most obvious in the free recall tasks than in the tracing or copying tasks. Measures such as pauses, patterns of drawings, and transitions among patterns of drawings suggested that participants used chunking to aid rapid learning of the diagram. The analysis of the participants' sequence of chunk production further revealed that they used a spatial schema to organize the chunks. Findings from this study provide additional evidence to support prior studies that claim graphical information is hierarchically organized.

Matched MeSH terms: Female

Fulltext Leprosy in Sarawak, Borneo: a 5 year review from 2008 to 2012

Ling HN

Lepr Rev, 2014 Dec;85(4):332-5.

PMID: 25675658

Matched MeSH terms: Female

Description of a new species of Uroballus Simon, 1902 (Araneae: Salticidae) from Malaysia, with the longest spinnerets of any known jumping spider

Logunov DV

Zootaxa, 2014;3894:183-7.

PMID: 25544631 DOI: 10.11646/zootaxa.3894.1.16

A new species Uroballus koponeni sp. n. (♀) from Malaysia (Borneo) is diagnosed, illustrated and described. The genus is unusual for jumping spiders in having extremely long spinnerets.

Matched MeSH terms: Female

Influencing preferences for different types of causal explanation of complex events

Klein G, Rasmussen L, Lin MH, Hoffman RR, Case J

Hum Factors, 2014 Dec;56(8):1380-400.

PMID: 25509820

We examined preferences for different forms of causal explanations for indeterminate situations. Background: Klein and Hoffman distinguished several forms of causal explanations for indeterminate, complex situations: single-cause explanations, lists of causes, and explanations that interrelate several causes. What governs our preferences for single-cause (simple) versus multiple- cause (complex) explanations?

Matched MeSH terms: Female

Fulltext Factors associated with placenta praevia in primigravidas and its pregnancy outcome

Nur Azurah AG, Wan Zainol Z, Lim PS, Shafiee MN, Kampan N, Mohsin WS, et al.

ScientificWorldJournal, 2014;2014:270120.

PMID: 25478587 DOI: 10.1155/2014/270120

To examine the factors associated with placenta praevia in primigravidas and also compare the pregnancy outcomes between primigravidas and nonprimigravidas.

Matched MeSH terms: Female

Fulltext Description of Bryantinus gen. n. from Sarawak, and new distributional records for Cerochusa cilioceps in Thailand (Coleoptera: Staphylinidae: Pselaphinae)

Yin ZW, Li LZ

PLoS One, 2014;9(11):e113474.

PMID: 25409318 DOI: 10.1371/journal.pone.0113474

A new genus and species of the subtribe Batrisina from western Sarawak, Bryantinus matangus gen. et sp. n., is described, illustrated, and compared with related taxa. In addition, examination of a small series of batrisine material from Thailand revealed a new country record for Cerochusa cilioceps Yin & Nomura, which was previously known only from the island of Hainan in southern China.

Matched MeSH terms: Female

Fulltext Therapeutic-diagnostic evaluation of chronic cough amongst adults: causes, symptoms and management at the primary care level, Malaysia

Nantha YS

J Family Med Prim Care, 2014 Jul;3(3):207-12.

PMID: 25374855 DOI: 10.4103/2249-4863.141611

BACKGROUND: Patients presenting with chronic cough pose a common diagnostic dilemma during routine consultations at public primary care clinics in Malaysia. To date, there has been little attempt at designing a standardized model or algorithm to facilitate an accurate diagnosis of chronic cough. This study proposes a clinical method to detect the causes of chronic cough in a primary care setting in Malaysia.
MATERIALS AND METHODS: A total of 117 patients aged above 18 at an urban primary care clinic were tracked over a span of 5 months to diagnose the cause of chronic cough. A therapeutic-diagnostic method was employed to help identify the causes of chronic cough. Subsequently, the demographic details of patients, the prevalence of the different causes of chronic cough and the relationship between history and diagnosis were analyzed statistically.
RESULTS: Chronic cough had a slightly higher male preponderance (51.3% vs. 48.7%). Patients within the 'above 60' age category had the highest frequency of chronic cough. The most common cause of chronic cough was post-infectious cough (n = 42, 35.9%), followed closely by angiotensin-converting enzyme-inhibitor related cough (n = 14, 12%). Majority of patients had the symptom of phlegm production (n = 41, 54%). 33 patients (29.2%) had recent upper respiratory tract infection (<2 weeks ago) prior to the diagnosis of chronic cough. There were poor association between symptoms and the various entities comprising chronic cough. The exceptions were the following associations: (1) Bronchial asthma and itchiness of throat (P = 0021), (2) gastroesophageal reflux disease and heartburn (P < 0.001), (3) upper airway cough syndrome and running nose (P = 0.016) and (4) pulmonary tuberculosis and absence of weight loss (P = 0.004).
CONCLUSION: This study demonstrates that the effectiveness of a therapeutic-diagnostic technique in the diagnosis of chronic cough. Consistent with previous studies, there was poor association between most symptoms and the causes of chronic cough. A study involving a larger primary care population is required to confirm the findings found in this analysis.
KEYWORDS: Angiotensin-converting enzyme-I related cough; chronic cough; post-infectious cough; primary care; therapeutic-diagnostic evaluation

Matched MeSH terms: Female

Fulltext Influence of refractive condition on retinal vasculature complexity in younger subjects

Azemin MZ, Daud NM, Ab Hamid F, Zahari I, Sapuan AH

ScientificWorldJournal, 2014;2014:783525.

PMID: 25371914 DOI: 10.1155/2014/783525

The aim of this study was to compare the retinal vasculature complexity between emmetropia, and myopia in younger subjects.

Matched MeSH terms: Female

Fulltext Successful Pregnancy Outcome in Malaysian Woman with Rare p Phenotype and Anti-PP1P(k) Antibody

Mohd Azri MS, Kunasegaran K, Azrina A, Siti Nadiah AK

Indian J Hematol Blood Transfus, 2014 Sep;30(Suppl 1):405-8.

PMID: 25332632 DOI: 10.1007/s12288-014-0439-4

We report the first case of young woman with the p phenotype and anti-PP1P(k) antibody in the Malaysian population who was identified during a blood grouping and antibody screening procedure after her first miscarriage. Further family screening detected two other siblings who possessed the same rare phenotype and antibody. Because of difficulties in finding compatible units in the local population, the patient and her two siblings were advised to become regular blood donor. Their blood was frozen for future use. After she had two recurrent miscarriages, her third pregnancy was successfully managed using oral dydrogesterone, which was started from 10 weeks into the pregnancy. Her pregnancy was uneventful and she gave birth to a healthy term neonate.

Matched MeSH terms: Female

Coffee consumption and coronary artery calcium in young and middle-aged asymptomatic adults

Choi Y, Chang Y, Ryu S, Cho J, Rampal S, Zhang Y, et al.

Heart, 2015 May;101(9):686-91.

PMID: 25732752 DOI: 10.1136/heartjnl-2014-306663

To investigate the association between regular coffee consumption and the prevalence of coronary artery calcium (CAC) in a large sample of young and middle-aged asymptomatic men and women.

Matched MeSH terms: Female

Perception of lower extremity loading in stroke

Kumar SN, Joseph LH, Pharmy Jalil A

Clin Neurophysiol, 2015 Jul;126(7):1453-4.

PMID: 25468242 DOI: 10.1016/j.clinph.2014.09.031

Matched MeSH terms: Female

A new species of Leptolalax from Sarawak, Western Borneo (Anura: Megophryidae)

Matsui M, Zainudin R, Nishikawa K

Zoolog Sci, 2014 Nov;31(11):773-9.

PMID: 25366161 DOI: 10.2108/zs140137

A new megophryid species is described from southwestern Sarawak, Malaysian Borneo. In appearance, Leptolalax marmoratus sp. nov. is most similar to L. hamidi also from southwestern Sarawak, but differs from it by mtDNA sequence, larger body size, and higher dominant frequency of advertisement call. The assumption that more than one species of Leptolalax coexist at one locality in Borneo is supported. The finding of the new species raises the species number of Leptolalax known from Borneo to nine, and the island is thought to be one of the diversification centers of the genus.

Matched MeSH terms: Female

Relationship between performance barriers and pharmacist competency towards the implementation of an expanded public health pharmacy role

Mathialagan A, Nagalinggam P, Mathialagan S, Kirby BP

Int J Pharm Pract, 2015 Oct;23(5):320-6.

PMID: 25582973 DOI: 10.1111/ijpp.12170

The objective of this study was to examine the relationship between performance barriers and competency, and implementation of an expanded public health role for community pharmacists.

Matched MeSH terms: Female

A comparison of pressure distributions between two types of sockets in a bulbous stump

Gholizadeh H, Abu Osman NA, Eshraghi A, Arifin N, Chung TY

Prosthet Orthot Int, 2016 Aug;40(4):509-16.

PMID: 25583929 DOI: 10.1177/0309364614564022

BACKGROUND: This article describes a total surface bearing prosthetic socket for a patient (25-year-old female) with a bulbous stump.

CASE DESCRIPTION AND METHODS: The subject had unstable excessive soft tissue at the distal end of the residuum. After 2 years of prosthetic use, she experienced several problems, including pain in the residual limb and knee joint. Pressure distribution was evaluated during ambulation. We also designed a total surface bearing socket with Velcro as suspension system to distribute the load evenly on the residual limb, and to facilitate donning procedure.

FINDINGS AND OUTCOMES: The main site of weight bearing in the old prosthesis (patellar tendon bearing) was anterior proximal region of the residual limb, especially the patellar tendon. The pressure was almost 10 times higher than the distal region during level walking. Pressures were distributed more evenly with the total surface bearing socket design, and the donning was much easier.

CONCLUSION: Pressure distribution within the socket could be affected by socket design and suspension system. Using the total surface bearing socket and Velcro as suspension system might facilitate donning of prosthesis and reduce traction at the end of residual limb during the swing phase of gait.

CLINICAL RELEVANCE: Proper socket design and suspension system based on the amputees' need can facilitate rehabilitation process and lead to the amputee's satisfaction. The pressure is distributed more uniformly over the residual limb by the total surface bearing socket compared to the patellar tendon bearing socket for lower limb amputees with unusual stump shape.

Matched MeSH terms: Female

Fulltext A review of depression research in Malaysia

Ng CG

Med J Malaysia, 2014 Aug;69 Suppl A:42-5.

PMID: 25417950 MyJurnal

Depression is a debilitating illness and has become a leading cause of morbidity globally. We aim to summarise the evidence available in regard to the prevalence, type of assessment tools used and treatment options for depression in Malaysia. Two hundred and forty seven articles related to depression were found in a search through a database dedicated to indexing all original data relevant to medicine published in Malaysia between the years 2000-2013. Fifty seven articles were selected and reviewed on the basis of clinical relevance and future research implications. Findings were summarised, categorised and presented according to prevalence of depression, depression in women, depression in clinical condition, assessment tools, and treatment of depression. The prevalence of depression in Malaysia was estimated to be between 8 and 12%. The figures were higher among women of low socio-economic background or those with comorbid medical condition. The common assessment tools used in Malaysia include Beck Depression Inventory (BDI), Depression, Anxiety and Stress Scale (DASS), Patient Health Questionnaire 9 (PHQ-9) and Hospital Anxiety and Depression Scale (HADS). They were translated into the Malay language and their psychometric properties were established. Both pharmacological treatment and psychotherapy were commonly used in Malaysia, and were highly recommended in local clinical practice guidelines. There are discrepancies in the reported rates of depression in Malaysia and this needs to be addressed. There were lack of studies looking into the depression among subgroups in Malaysia especially in the male population. There were several instruments available for assessment of depression in Malaysia but their suitability for the local setting need further research. Both pharmacotherapy and psychotherapy were recommended in the local treatment guideline in Malaysia. With the emergence of generic medication, we need to compare their clinical efficacy and tolerability with original products.

Matched MeSH terms: Female

Fulltext The development and validation of the Satisfaction Questionnaire for Osteoporosis Prevention in Malaysia

Toh LS, Lai PS, Wu DB, Wong KT, Low BY, Tan AT, et al.

Patient Prefer Adherence, 2014;8:1365-81.

PMID: 25328386 DOI: 10.2147/PPA.S65718

Purpose: To develop and validate the English version of the Satisfaction Questionnaire for Osteoporosis Prevention (SQOP) in Malaysia.
Methods: The SQOP was modified from the Osteoporosis Patient Satisfaction Questionnaire and developed based on literature review and patient interviews. Face and content validity were established via an expert panel. The SQOP consists of two sections: clinical services and types of counseling. There were 23 items in total, each with a five-point Likert-type response. Satisfaction score was calculated by converting the total score to a percentage. A higher score indicates higher satisfaction. English speaking, non-osteoporotic, postmenopausal women aged 50 years were included in the study. Participants were randomized to either the control or intervention group. Intervention participants were provided counseling, whereas control participants received none. Participants answered the SQOP at baseline and 2 weeks later.
Results: A total of 140 participants were recruited (control group: n=70; intervention group: n=70). No significant differences were found in any demographic aspects. Exploratory factor analysis extracted seven domains. Cronbach’s α for the domains ranged from 0.531–0.812. All 23 items were highly correlated using Spearman’s correlation coefficient 0.469–0.996 (P<0.05), with no significant change in the control group’s overall test–retest scores, indicating that the
SQOP achieved stable reliability. The intervention group had a higher score than the control group (87.91±5.99 versus 61.87±8.76; P<0.05), indicating that they were more satisfied than control participants. Flesch reading ease was 62.9.
Conclusion: The SQOP was found to be a valid and reliable instrument for assessing patients’ satisfaction towards an osteoporosis screening and prevention service in Malaysia.
Keywords: patient satisfaction, randomized controlled trial, postmenopausal women, screening
Study site: primary care clinic, tertiary hospital, Malaysia

Matched MeSH terms: Female

Search for displaced supersymmetry in events with an electron and a muon with large impact parameters

Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Bergauer T, Dragicevic M, et al.

Phys Rev Lett, 2015 Feb 13;114(6):061801.

PMID: 25723204

A search for new long-lived particles decaying to leptons is presented using proton-proton collisions produced by the LHC at √[s]=8 TeV. Data used for the analysis were collected by the CMS detector and correspond to an integrated luminosity of 19.7 fb(-1). Events are selected with an electron and muon with opposite charges that both have transverse impact parameter values between 0.02 and 2 cm. The search has been designed to be sensitive to a wide range of models with nonprompt e-μ final states. Limits are set on the "displaced supersymmetry" model, with pair production of top squarks decaying into an e-μ final state via R-parity-violating interactions. The results are the most restrictive to date on this model, with the most stringent limit being obtained for a top squark lifetime corresponding to cτ=2 cm, excluding masses below 790 GeV at 95% confidence level.

Matched MeSH terms: Female

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