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Fulltext Four ways blue foods can help achieve food system ambitions across nations

Crona BI, Wassénius E, Jonell M, Koehn JZ, Short R, Tigchelaar M, et al.

Nature, 2023 Apr;616(7955):104-112.
PMID: 36813964 DOI: 10.1038/s41586-023-05737-x

Blue foods, sourced in aquatic environments, are important for the economies, livelihoods, nutritional security and cultures of people in many nations. They are often nutrient rich1, generate lower emissions and impacts on land and water than many terrestrial meats2, and contribute to the health3, wellbeing and livelihoods of many rural communities4. The Blue Food Assessment recently evaluated nutritional, environmental, economic and justice dimensions of blue foods globally. Here we integrate these findings and translate them into four policy objectives to help realize the contributions that blue foods can make to national food systems around the world: ensuring supplies of critical nutrients, providing healthy alternatives to terrestrial meat, reducing dietary environmental footprints and safeguarding blue food contributions to nutrition, just economies and livelihoods under a changing climate. To account for how context-specific environmental, socio-economic and cultural aspects affect this contribution, we assess the relevance of each policy objective for individual countries, and examine associated co-benefits and trade-offs at national and international scales. We find that in many African and South American nations, facilitating consumption of culturally relevant blue food, especially among nutritionally vulnerable population segments, could address vitamin B12 and omega-3 deficiencies. Meanwhile, in many global North nations, cardiovascular disease rates and large greenhouse gas footprints from ruminant meat intake could be lowered through moderate consumption of seafood with low environmental impact. The analytical framework we provide also identifies countries with high future risk, for whom climate adaptation of blue food systems will be particularly important. Overall the framework helps decision makers to assess the blue food policy objectives most relevant to their geographies, and to compare and contrast the benefits and trade-offs associated with pursuing these objectives.

Matched MeSH terms: Environment; Environmental Policy
Fulltext Imperative: reducing the environmental impact of clinical laboratories

Gammie AJ, Lopez JB, Scott S

Clin Chem Lab Med, 2023 Mar 28;61(4):634-637.
PMID: 36343330 DOI: 10.1515/cclm-2022-1052

Clinical laboratories are significant contributors to the environmental burden of the planet. They have been slow to address the issues with a few exceptions, but it is highly encouraging to see the current impetus and ambition in this direction. This paper describes some of these initiatives and provides the rationale as to why clinical laboratories should become sustainable. It also describes the economic and intangible benefits that labs will accrue in achieving sustainability.

Matched MeSH terms: Environment
Fulltext Connectedness among Urban Parks from the Users' Perspective: A Systematic Literature Review

Li J, Md Dali M, Nordin NA

Int J Environ Res Public Health, 2023 Feb 18;20(4).
PMID: 36834348 DOI: 10.3390/ijerph20043652

Although many benefits of urban green space networks have been consistently demonstrated, most of the discussion on space connectivity has concentrated on ecological aspects, such as patch-corridor-matrix connectivity. There are limited systematic studies that have investigated the connectedness between urban parks and people. This study aimed to explore the connectedness among urban parks from the users' perspective by using a systematic literature review. By following the PRISMA protocol and analyzing 54 studies from Scopus and Web of Science between 2017 and 2022, we proposed the concepts of physical connectedness and perceived connectedness. The "physical connectedness" contained the dimensions of road attributes and park attributes, as well as six categories including physical accessibility, street connectivity, the street environment, spatial scale, facilities and amenities, and natural elements. The "perceived connectedness" mainly referred to people's perception of the physical environment. The four categories were perceived accessibility, perceived safety, aesthetics, and Kaplan's perceptual model. Finally, in terms of individual attributes, the impact of sociodemographic factors (age, gender, income, education, and occupation) and the motivation for activity on park connectedness were also taken into account. On the basis of our findings, this study suggested that park connectedness should not only focus on physical connectedness but also perceived connectedness.

Matched MeSH terms: Environment; Environment Design
Fulltext Improvement of trip generation rates for mixed-use development in Klang Valley, Malaysia

Goh BH, Yuen CW, Onn CC

Sci Rep, 2023 Feb 15;13(1):2699.
PMID: 36792761 DOI: 10.1038/s41598-023-29748-w

Mixed-use developments (MXDs) are a single development project that integrates and interacts with different land uses. Traffic is estimated to be reduced with such development. However, there is no standard procedure is available to estimate the MXD trip generation rates in Malaysia. The Malaysian Trip Generation Manual (MTGM) is the guidelines currently been used to forecast future trips for single land use. If the trip generation rates for multiple land uses are summed as MXD trips, the total trips will be overestimated without considering the internal trip capture. This study aimed to establish an improved method for estimating the MXD trip generation rates. Four MXD observation sites were selected in Klang Valley. Traffic survey counts were conducted considering person-trip, including passengers in vehicles and pedestrians. The results revealed that the MXD trip generation rates with MTGM were higher than actual traffic counts during peak hours. The MXD adjustment factor was established as 0.63, which can be applied by multiplying the MTGM trip generation rates to reduce the generated MXD trips in PCU per hour. This research has formulated a new data collection method by integrating person counts, alongside with new guidelines for pedestrian counts. The findings provide an option to adjust the MXD trips and prevent from overestimating future trips, which may result in overdevelopment and spending on mitigation measures in urban planning and road infrastructure.

Matched MeSH terms: Environment*
Fulltext The Residential Environment and Health and Well-Being of Chinese Migrant Populations: A Systematic Review

Huang L, Said R, Goh HC, Cao Y

Int J Environ Res Public Health, 2023 Feb 08;20(4).
PMID: 36833663 DOI: 10.3390/ijerph20042968

China's internal migrants suffer from marginalised housing conditions, poor neighbourhood environments and residential segregation, which may have significant implications on health and well-being. Echoing recent calls for interdisciplinary research on migrant health and well-being, this study examines the associations and mechanisms of the impact of the residential environment on the health and well-being of Chinese migrants. We found that most of the relevant studies supported the "healthy migration effect", but the phenomenon was only applicable to migrants' self-reported physical health rather than mental health. The subjective well-being of migrants is lower than that of urban migrants. There is a debate between the effectiveness of residential environmental improvements and the ineffectiveness of residential environmental improvements in terms of the impact of the neighbourhood environment on migrants' health and well-being. Housing conditions and the neighbourhood's physical and social environment can enhance migrants' health and well-being by strengthening place attachment and social cohesion, building localised social capital and gaining neighbourhood social support. Residential segregation on the neighbourhood scale affects the health outcomes of migrant populations through the mechanism of relative deprivation. Our studies build a vivid and comprehensive picture of research to understand migration, urban life and health and well-being.

Matched MeSH terms: Environment; Social Environment
The influence of safety leadership on nurses' safety behavior: The mediating role of safety knowledge and motivation

Subramaniam C, Johari J, Mashi MS, Mohamad R

J Safety Res, 2023 Feb;84:117-128.
PMID: 36868640 DOI: 10.1016/j.jsr.2022.10.013

INTRODUCTION: This paper investigates the relationships among safety leadership, safety motivation, safety knowledge, and safety behavior in the setting of a tertiary hospital in Klang Valley, Malaysia.
METHOD: Underpinned by the self-efficacy theory, we argue that high-quality safety leadership enhances nurses' safety knowledge and motivation and subsequently, improves their safety behavior (safety compliance and safety participation). A total of 332 questionnaire responses were gathered and analyzed using SmartPLS Version 3.2.9, revealing the direct effect of safety leadership on both safety knowledge and safety motivation.
RESULTS: Safety knowledge and safety motivation were found to directly and significantly predict nurses' safety behavior. Notably, safety knowledge and safety motivation were established as important mediators in the relationship between safety leadership and nurses' safety compliance and participation.
PRACTICAL APPLICATIONS: The findings of this study offer key guidance for safety researchers and hospital practitioners in identifying mechanisms to enhance safety behavior among nurses.

Matched MeSH terms: Environment
Integration of renewable energy and technological innovation in realizing environmental sustainability: the role of human capital in EKC framework

Saqib N, Sharif A, Razzaq A, Usman M

Environ Sci Pollut Res Int, 2023 Feb;30(6):16372-16385.
PMID: 36181595 DOI: 10.1007/s11356-022-23345-6

For the purpose of this study, the role of technological innovation is examined. Few studies have examined empirically and theoretically the relationship between technological innovation and ecological footprint in conjunction with other factors, such as the human capital index and renewable energy sources, such as biofuels and nuclear power. This study examines the impact of technological innovation on G-7 countries' ecological footprints from 1990 to 2020. A cross-sectionally augmented autoregressive distributed lag (CS-ARDL) model is used in the study. The results of the study show that technological innovation minimizes the ecological footprint. A lower ecological footprint is also associated with increased usage of human capital and renewable energy. Depletion of the natural environment is a short-term and long-term consequence of increased GDP growth. Our results confirm that ecologically sustainable technology enhances the quality of the environment. Consistent panel causality results were achieved. In the context of the G-7 countries, our study's results could support the idea that there are new policy ideas that could help achieve the Sustainable Development Goals (SDG 3, 4, 7, 8, 9, and 13).

Matched MeSH terms: Environment
Economic and environmental life cycle perspectives on two engineered wood products: comparison of LVL and GLT construction materials

Balasbaneh AT, Sher W, Yeoh D, Yasin MN

Environ Sci Pollut Res Int, 2023 Feb;30(10):26964-26981.
PMID: 36374387 DOI: 10.1007/s11356-022-24079-1

The embodied carbon of building materials and the energy consumed during construction have a significant impact on the environmental credentials of buildings. The structural systems of a building present opportunities to reduce environmental emissions and energy. In this regard, mass timber materials have considerable potential as sustainable materials over other alternatives such as steel and concrete. The aim of this investigation was to compare the environment impact, energy consumption, and life cycle cost (LCC) of different wood-based materials in identical single-story residential buildings. The materials compared are laminated veneer lumber (LVL) and glued laminated timber (GLT). GLT has less global warming potential (GWP), ozone layer depletion (OLD), and land use (LU), respectively, by 29%, 37%, and 35% than LVL. Conversely, LVL generally has lower terrestrial acidification potential (TAP), human toxicity potential (HTP), and fossil depletion potential (FDP), respectively, by 30%, 17%, and 27%. The comparative outcomes revealed that using LVL reduces embodied energy by 41%. To identify which of these materials is the best alternative, various environmental categories, embodied energy, and cost criteria require further analysis. Therefore, the multi-criteria decision-making (MCDM) method has been applied to enable robust decision-making. The outcome showed that LVL manufacturing using softwood presents the most sustainable choice. These research findings contribute to the body of knowledge about the use of mass timber in construction.

Matched MeSH terms: Environment
Fulltext Perceived unmet needs of an age-friendly environment: A qualitative exploration of older adults' perspectives in a Malaysian city

Lim XJ, Chew CC, Chang CT, Supramaniam P, Ding LM, Devesahayam PR, et al.

PLoS One, 2023;18(6):e0286638.
PMID: 37279237 DOI: 10.1371/journal.pone.0286638

This exploratory qualitative study investigates older adults' unmet needs in the age-friendly city of Ipoh, Malaysia. Seventeen participants were interviewed, including ten older adults residing in Ipoh City for at least six months, four carers, and three professional key informants. Interviews were conducted using semi-structured questions based on the WHO Age-Friendly Cities Framework. A 5P framework for active ageing based on the ecological ageing model was adapted for data analysis. The 5P framework consists of domains of person (micro), process (meso), place (macro), policymaking (macro), and prime, which allows for the dissection of older adults' unmet needs in planning for multilevel approaches, which were employed for analysis. Person: the personal needs requiring improvement included digital divide disparity, inadequate family support, and restricted sports activities attributed to physical limitations. Process: There were fewer social activities and a lack of low-cost and easily accessible venues for seniors. Economic challenges include expensive private healthcare services, variation in the quality of care in older residential care facilities, and limited savings for retirement. Place issues include unequal distribution of exercise equipment, public open spaces, the need for more conducive parking for seniors, and a place for social activities. Difficulties assessing public transportation, digitalized services, and unaffordable e-hailing services are common among seniors. Housing issues for seniors include a lack of barrier-free housing design and unaffordable housing. Policymaking: Insufficient private sector commitment to improving services to older adults, lack of policy governance on the quality of nursing homes, and insufficient multidisciplinary governance collaboration. Prime: Health promotion for preventing age-related illness is required to preserve health in old age, and full-time family caregivers' psychological well-being is often overlooked.

Matched MeSH terms: Environment; Social Environment*
Fulltext The Molecular Effects of Environmental Enrichment on Alzheimer's Disease

Liew AKY, Teo CH, Soga T

Mol Neurobiol, 2022 Dec;59(12):7095-7118.
PMID: 36083518 DOI: 10.1007/s12035-022-03016-w

Environmental enrichment (EE) is an environmental paradigm encompassing sensory, cognitive, and physical stimulation at a heightened level. Previous studies have reported the beneficial effects of EE in the brain, particularly in the hippocampus. EE improves cognitive function as well as ameliorates depressive and anxiety-like behaviors, making it a potentially effective neuroprotective strategy against neurodegenerative diseases such as Alzheimer's disease (AD). Here, we summarize the current evidence for EE as a neuroprotective strategy as well as the potential molecular pathways that can explain the effects of EE from a biochemical perspective using animal models. The effectiveness of EE in enhancing brain activity against neurodegeneration is explored with a view to differences present in early and late life EE exposure, with its potential application in human being discussed. We discuss EE as one of the non pharmacological approaches in preventing or delaying the onset of AD for future research.

Matched MeSH terms: Environment
A comparison of dust impacts on polycrystalline and monocrystalline solar photovoltaic performance: an outdoor experimental study

Kazem HA, Chaichan MT, Al-Waeli AHA

Environ Sci Pollut Res Int, 2022 Dec;29(59):88788-88802.
PMID: 35836053 DOI: 10.1007/s11356-022-21958-5

Solar cells are considered one of the most important and widespread solar applications in the world. However, the performance of the PV modules is significantly affected by the dust in the air. This paper, therefore, presents a comparison of an outdoor experimental study of dust effect on monocrystalline, and polycrystalline photovoltaic (PV) modules. For analysis, four 100 W PVs were installed horizontally in Sohar, Oman. For each pair of PV modules, one was left dusty due to environmental impact, and the second was cleaned daily. PV performance and environmental parameter measurements were conducted every 30 min for 35 days. The effects of dust on current, voltage, power, and energy were discussed in terms of time and normalized values. Also, cleaning methods were tested to determine the optimum one. It is found that power degradation of monocrystalline (20%) is higher compared with polycrystalline (12%) due to dust accumulation. For monocrystalline, the current, voltage, and power losses ranged between 10.0-24.0%, 2.0-3.5%, and 14.0-31.0%, respectively. However, for polycrystalline, the degradation rates were 16.88-27.92%, 0.455-0.455%, and 17.14-28.1% for current, voltage, and power losses after exposure to outdoor conditions for the same period, respectively. The dust accumulation on the PV surface found after 5 weeks is 0.493 mg/cm2, which can be considered the lowest accumulation rate compared to other Gulf countries, but which, however, leads to less energy degradation as well. It is found that water is sufficient to clean PV in the study area. However, sodium detergent as a cleaner introduced better results compared to water, especially when there is high pollution in the location.

Matched MeSH terms: Environment
Fulltext Hereditary analysis and genotype × environment interaction effects on growth and yield components of Bambara groundnut (Vigna subterranea (L.) Verdc.) over multi-environments

Khan MMH, Rafii MY, Ramlee SI, Jusoh M, Al Mamun M

Sci Rep, 2022 09 19;12(1):15658.
PMID: 36123374 DOI: 10.1038/s41598-022-19003-z

This investigation was carried out to explore G × E interaction for yield and its associated attributes in 30 Bambara groundnut genotypes across four environments in tropical Malaysia. Such evaluations are essential when the breeding program's objective is to choose genotypes with broad adaption and yield potential. Studies of trait relationships, variance components, mean performance, and genetic linkage are needed by breeders when designing, evaluating, and developing selection criteria for improving desired characteristics in breeding programs. The evaluation of breeding lines of Bambara groundnut for high yield across a wide range of environments is important for long-term production and food security. Each site's experiment employed a randomized complete block design with three replicates. Data on vegetative and yield component attributes were recorded. The analysis of variance revealed that there were highly significant (p ≤ 0.01) differences among the 30 genotypes for all variables evaluated. A highly significant and positive correlation was identified between yield per hectare and dry seed weight (0.940), hundred seed weight (0.844), fresh pod weight (0.832), and total pod weight (0.750); the estimated correlation between dry weight of pods and seed yield was 1.0. The environment was more important than genotype and G × E in determining yield and yield components.A total of 49% variation is covered by PC1 (33.9%) and PC2 (15.1%) and the genotypes formed five distinct clusters based on Ward hierarchical clustering (WHC) method. The genotypes S5G1, S5G3, S5G5, S5G6, S5G8, S5G7, S5G2, S5G4, S5G10, S5G13, S5G11, and S5G14 of clusters I, II, and III were closest to the ideal genotype with superior yield across the environments. The PCA variable loadings revealed that an index based on dry pod weight, hundred seed weight, number of total pods and fresh pod weight could be used as a selection criteria to improve seed yield of Bambara groundnut.

Matched MeSH terms: Gene-Environment Interaction
An integrated life cycle multi-objective optimization model for health-environment-economic nexus in food waste management sector

Lin Z, Ooi JK, Woon KS

Sci Total Environ, 2022 Apr 10;816:151541.
PMID: 34774629 DOI: 10.1016/j.scitotenv.2021.151541

Food waste is a universal problem in many countries. In line with Sustainable Development Goals 7 and 12, it is crucial to identify a cost-effective food waste valorization management framework with the least human health and environmental impacts. However, studies on the synergistic effect of life cycle assessment and mathematical optimization interconnected with human health, environment, and economic are relatively few and far between; hence they cannot provide holistic recommendations to policymakers in developing environmental and economic feasibility of food waste management frameworks. Taking Malaysia as a case study, this study proposes a simple and deterministic model that integrates life cycle assessment and multi-objective mathematical optimization to unpack the health-environment-economic wellbeing nexus in food waste management sector. The model evaluates the life cycle human health, environmental, and economic impacts of five food waste disposal and valorization technologies: open landfill, sanitary landfill, aerated windrow composting, high-temperature drying sterilization, and anaerobic digestion, and identifies the optimal food waste valorization configuration solution in Malaysia. Based on the results modeled by SimaPro 9.0 and General Algebraic Modeling System with augmented ε-constraint, valorization of food waste into electricity via anaerobic digestion is the most favorable option, with 146% and 161% reduction of human health and ecosystems, respectively, as compared with open landfill. If cost is combined as an objective function with human health and ecosystems, high-temperature drying sterilization is the most attractive scenario due to the high livestock feed revenue. Among the 10 Pareto-optimal solutions, 9% sanitary landfill, 3% aerated windrow composting, 30% high-temperature drying sterilization, 30% anaerobic digestion to electricity, and 28% anaerobic digestion to cooking gas, is recommended as future food waste management configuration. The sensitivity results demonstrate that prices of electricity, cooking gas, and livestock feed affect the optimal configuration food waste management system.

Matched MeSH terms: Environment
Perceived impacts of Urban Heat Island phenomenon in a tropical metropolitan city: Perspectives from stakeholder dialogue sessions

Aghamohammadi N, Ramakreshnan L, Fong CS, Noor RM, Hanif NR, Sulaiman NM

Sci Total Environ, 2022 Feb 01;806(Pt 1):150331.
PMID: 34571225 DOI: 10.1016/j.scitotenv.2021.150331

The stakeholders' perceptions on the impacts of Urban Heat Island (UHI) are critical for reducing exposure and influencing their response to interventions that are aimed at encouraging a behaviour change. A proper understanding of the UHI impacts on the society, economy and environment is deemed an essential motivating factor for the stakeholders to work towards UHI mitigations in the local context. This study adopted an inductive qualitative approach using Stakeholder Dialogue Sessions (SDSs) to assess the perceived impacts of UHI among various stakeholders, comprising policy makers, academicians, developers and Non-Governmental Organizations (NGO), in a tropical metropolitan city. The results revealed five themes such as deterioration of public health, acceleration of urban migration patterns and spending time in cooler areas, reduction of workers' productivity, increased energy consumption by the households and deterioration of environmental quality and natural resources that were categorized into social, economic and environmental impacts. Although most of the stakeholders were quite unfamiliar with the term UHI, they still display a good understanding of the potential impacts of UHI due to their posteriori knowledge and ability to rationalize the physical condition of the environment in which they live. The findings provide useful insights and valuable information to the local authorities to tailor necessary actions and educational campaigns to increase UHI awareness among the stakeholders. Being among the earlier studies to use a qualitative approach to attain the aforementioned objective, the findings are crucial to determine the level of understanding of the stakeholders on the impact of UHI. Through this study, the authors have highlighted the gaps and needs for knowledge improvements aimed at behaviour change among the stakeholders.

Matched MeSH terms: Environment*
Assessment of spatial and temporal ecological environment quality under land use change of urban agglomeration in the North Slope of Tianshan, China

Airiken M, Zhang F, Chan NW, Kung HT

Environ Sci Pollut Res Int, 2022 Feb;29(8):12282-12299.
PMID: 34564811 DOI: 10.1007/s11356-021-16579-3

In the current context of rapid development and urbanization, land use and land cover (LULC) types have undergone unprecedented changes, globally and nationally, leading to significant effects on the surrounding ecological environment quality (EEQ). The urban agglomeration in North Slope of Tianshan (UANST) is in the core area of the Silk Road Economic Belt of China. This area has experienced rapid development and urbanization with equally rapid LULC changes which affect the EEQ. Hence, this study quantified and assessed the spatial-temporal changes of LULC on the UANST from 2001 to 2018 based on remote sensing analysis. Combining five remote sensing ecological factors (WET, NDVI, IBI, TVDI, LST) that met the pressure-state-response(PSR) framework, the spatial-temporal distribution characteristics of EEQ were evaluated by synthesizing a new Remote Sensing Ecological Index (RSEI), with the interaction between land use change and EEQ subsequently analyzed. The results showed that LULC change dominated EEQ change on the UANST: (1) From 2001 to 2018, the temporal and spatial pattern of the landscape on the UANST has undergone tremendous changes. The main types of LULC in the UANST are Barren land and Grassland. (2) During the study period, RSEI values in the study area were all lower than 0.5 and were at the [good] levels, reaching 0.31, 0.213, 0.362, and 0346, respectively. In terms of time and space, the overall EEQ on the UANST experienced three stages of decline-rise-decrease. (3) The estimated changes in RSEI were highly related to the changes of LULC. During the period 2001 to 2018, the RSEI value of cropland showed a trend of gradual increase. However, the rest of the LULC type's RSEI values behave differently at different times. As the UANST is the core area of Xinjiang's urbanization and economic development, understanding and balancing the relationship between LULC and EEQ in the context of urbanization is of practical application in the planning and realization of sustainable ecological, environmental, urban, and social development in the UANST.

Matched MeSH terms: Environment; Environmental Monitoring*
Fulltext Study on the Construction and Development Path of Gymnasiums considering Ecological Environment Restrictions

Chen X, Zheng L, Xu Y

J Environ Public Health, 2022;2022:2700957.
PMID: 35978586 DOI: 10.1155/2022/2700957

Under the restriction of ecological and environmental factors, our requirements have improved for the development path of gymnasium construction. According to the previous way to carry out the development path of gymnasium construction will make our construction work encounter a lot of unnecessary troubles, so we can improve the success rate of the development path of gymnasium construction under the constraints of the ecological environment by carrying out relevant evasive operations according to the constraints of ecological environment. The topological path and path algorithm used to improve the efficiency of stadium construction and development path under the constraints of ecological environment, TEG algorithm, Q-TEG model, Q-TEG algorithm, Dtra algorithm, TraD algorithm, ResR algorithm, and Q-TED algorithm used in resource reservation plus time slot plus hosting bring the following advantages: (1) we use topological path and path algorithm to explore topological representation methods suitable for development path. The overview provides a theoretical basis for guidance, for forwarding technology scheduling mechanisms and multi-path forwarding mechanisms to provide higher flexibility. (2) We use the TEG algorithm of resource reservation plus time slot plus trusteeship, Q-TEG model, and Q-TEG algorithm under multi-model model can deal with the capacity and link of queue in each stadium construction development path well. It is more convenient to set the packet loss threshold for the propagation experiment tested in the simulation. Better help gymnasium construction and development path transmission is successful. (3) The use of the Dtra algorithm, TraD algorithm, ResR algorithm, and Q-TED algorithm in our stadium construction development path of a good deal of the transmission link structure between each node, so that the transmission efficiency between nodes becomes higher, making our stadium construction development path operation more efficient and convenient.

Matched MeSH terms: Environment
The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

Chan JCN, Lim LL, Wareham NJ, Shaw JE, Orchard TJ, Zhang P, et al.

Lancet, 2021 Dec 19;396(10267):2019-2082.
PMID: 33189186 DOI: 10.1016/S0140-6736(20)32374-6
Matched MeSH terms: Environment
Fulltext Evaluation of Clinical Practice Guidelines on Fall Prevention and Management for Older Adults: A Systematic Review

Montero-Odasso MM, Kamkar N, Pieruccini-Faria F, Osman A, Sarquis-Adamson Y, Close J, et al.

JAMA Netw Open, 2021 Dec 01;4(12):e2138911.
PMID: 34910151 DOI: 10.1001/jamanetworkopen.2021.38911

IMPORTANCE: With the global population aging, falls and fall-related injuries are ubiquitous, and several clinical practice guidelines for falls prevention and management for individuals 60 years or older have been developed. A systematic evaluation of the recommendations and agreement level is lacking.
OBJECTIVES: To perform a systematic review of clinical practice guidelines for falls prevention and management for adults 60 years or older in all settings (eg, community, acute care, and nursing homes), evaluate agreement in recommendations, and identify potential gaps.
EVIDENCE REVIEW: A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-analyses statement methods for clinical practice guidelines on fall prevention and management for older adults was conducted (updated July 1, 2021) using MEDLINE, PubMed, PsycINFO, Embase, CINAHL, the Cochrane Library, PEDro, and Epistemonikos databases. Medical Subject Headings search terms were related to falls, clinical practice guidelines, management and prevention, and older adults, with no restrictions on date, language, or setting for inclusion. Three independent reviewers selected records for full-text examination if they followed evidence- and consensus-based processes and assessed the quality of the guidelines using Appraisal of Guidelines for Research & Evaluation II (AGREE-II) criteria. The strength of the recommendations was evaluated using Grades of Recommendation, Assessment, Development, and Evaluation scores, and agreement across topic areas was assessed using the Fleiss κ statistic.
FINDINGS: Of 11 414 records identified, 159 were fully reviewed and assessed for eligibility, and 15 were included. All 15 selected guidelines had high-quality AGREE-II total scores (mean [SD], 80.1% [5.6%]), although individual quality domain scores for clinical applicability (mean [SD], 63.4% [11.4%]) and stakeholder (clinicians, patients, or caregivers) involvement (mean [SD], 76.3% [9.0%]) were lower. A total of 198 recommendations covering 16 topic areas in 15 guidelines were identified after screening 4767 abstracts that proceeded to 159 full texts. Most (≥11) guidelines strongly recommended performing risk stratification, assessment tests for gait and balance, fracture and osteoporosis management, multifactorial interventions, medication review, exercise promotion, environment modification, vision and footwear correction, referral to physiotherapy, and cardiovascular interventions. The strengths of the recommendations were inconsistent for vitamin D supplementation, addressing cognitive factors, and falls prevention education. Recommendations on use of hip protectors and digital technology or wearables were often missing. None of the examined guidelines included a patient or caregiver panel in their deliberations.
CONCLUSIONS AND RELEVANCE: This systematic review found that current clinical practice guidelines on fall prevention and management for older adults showed a high degree of agreement in several areas in which strong recommendations were made, whereas other topic areas did not achieve this level of consensus or coverage. Future guidelines should address clinical applicability of their recommendations and include perspectives of patients and other stakeholders.

Matched MeSH terms: Environment Design
Fulltext AMMI and GGE biplot analysis for yield performance and stability assessment of selected Bambara groundnut (Vigna subterranea L. Verdc.) genotypes under the multi-environmental trails (METs)

Khan MMH, Rafii MY, Ramlee SI, Jusoh M, Al Mamun M

Sci Rep, 2021 Nov 23;11(1):22791.
PMID: 34815427 DOI: 10.1038/s41598-021-01411-2

The stability and high yielding of Vigna subterranea L. Verdc. genotype is an important factor for long-term development and food security. The effects of G × E interaction on yield stability in 30 Bambara groundnut genotypes in four different Malaysian environments were investigated in this research. The experiment used a randomized complete block design with three replications in each environment. Over multiple harvests, yield component traits such as the total number of pods per plant, fresh pods weight (g), hundred seeds weight (g), and yield per hectare were evaluated in the main and off-season in 2020 and 2021. Stability tests for multivariate stability parameters were performed based on analyses of variance. For all the traits, the pooled analysis of variance revealed highly significant (p

Matched MeSH terms: Gene-Environment Interaction*
Hippocampal neural cell degeneration and memory deficit in high-fat diet-induced postnatal obese rats- exploring the comparable benefits of choline and DHA or environmental enrichment

Prabhu GS, K G Rao M, Rai KS

Int J Neurosci, 2021 Nov;131(11):1066-1077.
PMID: 32498586 DOI: 10.1080/00207454.2020.1773819

PURPOSE: Childhood obesity increases risk for neural dysfunctions causing learning and memory deficits. The objective of the study is to identify the effects of high fat diet-induced obesity in postnatal period on serum lipids, memory and neural cell survival in hippocampus and compare the role of choline and DHA or environmental enrichment in attenuating the alterations.
MATERIALS AND METHODS: 21 day postnatal male Sprague Dawley rats were assigned as Normal control [NC] fed normal chow diet, Obesity-induced [OB] fed high fat diet, Obesity-induced fed choline & DHA [OB + CHO + DHA], Obesity-induced environmental enrichment [OB + EE] [n = 8/group]. Memory was assessed using radial arm maze. Subsequently blood was collected for serum lipid analysis and rats were euthanized. 5 µm hippocampal sections were processed for cresyl-violet stain. Surviving neural cells were counted using 100 µm scale.
RESULTS: Memory errors were significantly higher [p

Matched MeSH terms: Environment*

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