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Fulltext Turnovers of Sex-Determining Mutation in the Golden Pompano and Related Species Provide Insights into Microevolution of Undifferentiated Sex Chromosome

Guo L, Malara D, Battaglia P, Waiho K, Davis DA, Deng Y, et al.

Genome Biol Evol, 2024 Mar 02;16(3).
PMID: 38408866 DOI: 10.1093/gbe/evae037

The suppression of recombination is considered a hallmark of sex chromosome evolution. However, previous research has identified undifferentiated sex chromosomes and sex determination by single SNP in the greater amberjack (Seriola dumerili). We observed the same phenomena in the golden pompano (Trachinotus ovatus) of the same family Carangidae and discovered a different sex-determining SNP within the same gene Hsd17b1. We propose an evolutionary model elucidating the turnover of sex-determining mutations by highlighting the contrasting dynamics between purifying selection, responsible for maintaining W-linked Hsd17b1, and neutral evolution, which drives Z-linked Hsd17b1. Additionally, sporadic loss-of-function mutations in W-linked Hsd17b1 contribute to the conversion of W chromosomes into Z chromosomes. This model was directly supported by simulations, closely related species, and indirectly by zebrafish mutants. These findings shed new light on the early stages of sex chromosome evolution.

Matched MeSH terms: Sex Chromosomes/genetics
Does TikTok Open Gates for Sexual Violence Against Young Girls in Bangladesh Amid COVID-19?

Rabby MII, Badiuzzaman M, Akhi IJ

Asia Pac J Public Health, 2022 01;34(1):149-150.
PMID: 34549622 DOI: 10.1177/10105395211046479
Matched MeSH terms: Sex Offenses*
Fulltext Female-specific SNP markers provide insights into a WZ/ZZ sex determination system for mud crabs Scylla paramamosain, S. tranquebarica and S. serrata with a rapid method for genetic sex identification

Shi X, Waiho K, Li X, Ikhwanuddin M, Miao G, Lin F, et al.

BMC Genomics, 2018 Dec 29;19(1):981.
PMID: 30594128 DOI: 10.1186/s12864-018-5380-8

BACKGROUND: Mud crabs, Scylla spp., are commercially important large-size marine crustaceans in the Indo-West Pacific region. As females have the higher growth rate and economic value, the production of all female stocks is extremely essential in aquaculture. However, the sex determination mechanism is still unclear. Development of sex-specific genetic markers based on next-generation sequencing proved to be an effective tool for discovering sex determination system in various animals.
RESULTS: Restriction-site associated DNA sequencing (RAD-seq) was employed to isolate sex-specific SNP markers for S. paramamosain. A total of 335.6 million raw reads were obtained from 20 individuals, of which 204.7 million were from 10 females and 130.9 million from 10 males. After sequence assembly and female-male comparison, 20 SNP markers were identified to be sex-specific. Furthermore, ten SNPs in a short sequence (285 bp) were confirmed heterozygous in females and homozygous in males in a large population by PCR amplification and sequencing. Subsequently, a female-specific primer was successfully designed according to the female-specific nucleotide which could amplify an expected band from females but not from males. Thus, a rapid and effective method for molecular sexing in S. paramamosain was developed, meanwhile, this method could successfully identify the sex of S. tranquebarica and S. serrata. Finally, nine and four female-specific SNP markers were detected in S. tranquebarica and S. serrata, respectively.
CONCLUSIONS: Sex-specific SNP markers were firstly identified in crab species and showed female heterogamety and male homogamety, which provided strong genetic evidence for a WZ/ZZ sex determination system in mud crabs S. paramamosain, S. tranquebarica and S. serrata. These findings will lay a solid foundation for the study of sex determination mechanism, sex chromosome evolution, and the development of mono-sex population in crustaceans.

Matched MeSH terms: Sex Chromosomes; Sex Determination Analysis/methods*; Sex Determination Processes*
Gender difference in academic performance of nursing students in a Malaysian university college

Wan Chik WZ, Salamonson Y, Everett B, Ramjan LM, Attwood N, Weaver R, et al.

Int Nurs Rev, 2012 Sep;59(3):387-93.
PMID: 22897191 DOI: 10.1111/j.1466-7657.2012.00989.x

To examine differences in academic performance between male and female nursing students, and to identify whether professional identity and language usage were explanatory factors of academic performance.

Matched MeSH terms: Sex Factors; Sex Ratio*
Fulltext Persistent müllerian duct syndrome--a case report

Yip CH, Chang KW

Singapore Med J, 1991 Oct;32(5):363-4.
PMID: 1788587

An eighteen month old phenotypically and genotypically normal male child was admitted with a left inguinal hernia and a right undescended testis. At operation, he was found to have a uterus, bilateral fallopian tubes, and a vagina in the left hernial sac. Bilateral orchidopexies and excision of the persistent Mullerian duct structures were carried out. This rare case of persistent Mullerian duct syndrome is due to a defect in Mullerian regression, which is in turn controlled by the Mullerian inhibiting substance (MIS). Orchidopexy with excision of the persistent Mullerian duct structures is usually not possible without damage to the vas deferens which is closely adherent to the wall of the uterus. The alternative of leaving the persistent Mullerian duct structures alone and performing a staged or primary orchidopexy has been suggested.

Matched MeSH terms: Disorders of Sex Development/etiology*; Disorders of Sex Development/surgery
On tests for sex preferences

Leung SF

J Popul Econ, 1988 Oct;1(2):95-114.
PMID: 12282511

"This paper presents a critical evaluation of three widely used tests for sex preferences: sex ratio, parity progression ratio and ordinary least squares [OLS] regression of birth interval. We show that under some appropriate conditions, the sex ratio is a valid test for sex preferences. The methods of parity progression ratio and OLS regression of birth interval fail to deal with right censoring and time varying covariates, which reduce the power of the tests. We suggest the use of hazard estimation to test for sex preferences. We demonstrate the differences among the tests by analyzing the retrospective fertility histories of the Chinese and the Malays in Malaysia. We find that unlike the two conventional methods, the hazard estimation gives clear and strong evidence of sex preferences among the Chinese in Malaysia."

Matched MeSH terms: Research; Sex*; Sex Factors; Sex Ratio*; Sex Distribution
Fulltext Impact of sexual health course on Malaysian university students

Low WY

Med J Malaysia, 2004 Oct;59(4):443-9.
PMID: 15779575 MyJurnal

A sexual health course was offered and taught by academic staff from the Faculty of Medicine, University of Malaya during semester II of every year as a university elective course to other university students apart from medical students. The course covered a wide range of topics: adolescent sexuality, family planning and pregnancy, violence against women, alternative sexual behavior, physiology of sex, sex and the disabled, gender bias in sexuality, relationship and marriage, sexual dysfunctions, clarification of sexual attitudes and STDs and AIDS. The Sexual Knowledge and Attitude Test (SKAT-II) was used to measure students' pre- and post-course scores on sexual knowledge and attitudes. Fifty-four students who completed both the pre- and post-course tests showed a significant change in sexual knowledge and their attitudes towards sexual myths and autoeroticism. Sexual knowledge was also positively correlated with age, heterosexual relations, autoeroticism and sexual myths scores. However, sexual knowledge is negatively related to religiosity and the influence of religious beliefs on one's attitudes towards sexual matters. This study showed that the sexual health course offered does have a positive impact in increasing one's knowledge and changing one's attitudes towards sexual issues.

Matched MeSH terms: Sex Education*
Fulltext Bringing X, Y, Z generations together to facilitate school-based sexual and reproductive health education

Kamrani MA, Syed Yahya S

Glob J Health Sci, 2016;8(9):54741.
PMID: 27157180 DOI: 10.5539/gjhs.v8n9p132

This generic qualitative study explores the perspective of Malaysian teachers regarding the constraints of the current school-based sexual and reproductive health education in secondary schools of Klang-Valley Malaysia. For this study, in-depth interviews were conducted with twenty eight science teachers of government schools. The majority of participants named the teaching strategy and capacity of teachers, the lack of co-operation from the school and parents, limited resources in teaching and students themselves as some of the challenges. We concluded that if sexual health education is to be effective, it needs to be provided by people who have some specialized training. The teachers should be trained to teach sexual reproductive health education classes at the basic level, and in-service training for teachers already in the field should be intensified. Local adaptation to culture, language, religion, and so forth is often necessary.

Matched MeSH terms: Sex Education*
Women--an endangered species

World Dev Forum, 1987 Nov 30;5(21):1-2.
PMID: 12269045

Throughout India and China, South Korea and Taiwan, Pakistan and Malaysia, the same sentiment recurs: "The birth of girl is an occasion for gloom, not cheer, for bitterness, not pleasure." In all these countries "patriarchal traditions and social stigmas" make females the unwanted sex, reports Asiaweek. The tragic result: prenatal gender tests are flourishing. And for many women, if the test indicates a female, they abort. In India, sex tests and abortions are legal, cheap and readily available. Some 1500 sex-tested girls are aborted annually in Bombay alone. In China, abortions are legal, but gender tests strictly forbidden. Says one official: We cannot afford to let people know what sex the fetus is because all the girls would be aborted." Yet the numbers of baby girls in China have been reduced--and illicit gender tests and female infanticide are considered partly to blame. In South Korea, gender tests have been banned and most abortions are illegal, but "clandestine tests" are available, and according to the government some 30,000 pregnancies are terminated annually. The number of aborted females is not known, but birth ratios have shown "an alarming swing towards males" in recent years. Can laws and education change the social attitudes against girls in these Asian countries? Indian activist Vibhuti Patel, a lobbyist for stronger controls over sex-testing, hopes so. She urges a "continuous campaign" to fight the "centuries-old values" that encourages gender tests. Says Patel: Nothing less than the very survival of women is at stake."

Matched MeSH terms: Family Planning Services; Sex*; Sex Factors*; Sex Ratio*; Sex Distribution*
Reactions to male-favouring versus female-favouring sex differences: A pre-registered experiment and Southeast Asian replication

Stewart-Williams S, Chang CYM, Wong XL, Blackburn JD, Thomas AG

Br J Psychol, 2021 May;112(2):389-411.
PMID: 32701171 DOI: 10.1111/bjop.12463

Two studies investigated (1) how people react to research describing a sex difference, depending on whether that difference favours males or females, and (2) how accurately people can predict how the average man and woman will react. In Study 1, Western participants (N = 492) viewed a fictional popular-science article describing either a male-favouring or a female-favouring sex difference (i.e., men/women draw better; women/men lie more). Both sexes reacted less positively to the male-favouring differences, judging the findings to be less important, less credible, and more offensive, harmful, and upsetting. Participants predicted that the average man and woman would react more positively to sex differences favouring their own sex. This was true of the average woman, although the level of own-sex favouritism was lower than participants predicted. It was not true, however, of the average man, who - like the average woman - reacted more positively to the female-favouring differences. Study 2 replicated these findings in a Southeast Asian sample (N = 336). Our results are consistent with the idea that both sexes are more protective of women than men, but that both exaggerate the level of same-sex favouritism within each sex - a misconception that could potentially harm relations between the sexes.

Matched MeSH terms: Sex Characteristics*
Presumptive X monosomy in black rats from Malaya

Hoi-Sen Y

Nature, 1971 Aug 13;232(5311):484-5.
PMID: 4937212
Matched MeSH terms: Sex Chromosomes*
Klinefelter's syndrome, a case report

Kutty MK, Dutt AK, Lopez G, Ramanathan K, Pillay DR, Omar-Ahmad UD

Med J Malaya, 1968 Sep;23(1):51-3.
PMID: 4237557
Matched MeSH terms: Sex Chromatin*
A survey of coffee shop prostitutes in Kuala Trengganu

HOLMES W

Med J Malaya, 1955 Dec;10(2):178-80.
PMID: 13308619
Matched MeSH terms: Sex Workers*
Anthropometric and Anthroposcopic Analysis of Periorbital Features in Malaysian Population: An Inter-racial Study

Packiriswamy V, Kumar P, Bashour M

Facial Plast Surg, 2018 Aug;34(4):400-406.
PMID: 29723879 DOI: 10.1055/s-0038-1648224

In oculoplastic operations, knowledge of the dimensions of periorbital features based on age, gender, and race is essential for achieving better aesthetic result. This article seeks to determine the racial and gender differences of periorbital features among Malaysian Malay (MM), Malaysian Indian (MI), and Malaysian Chinese (MI) subjects. Evaluation of periorbital features was done on photographs of 200 MM, 200 MI, and 200 MC subjects, aged 18 to 26 years. The measured values were evaluated by an independent t-test. A significant difference was found between MM and MI in all measurements except interbrow distance in males, eyebrow thickness in females, and apex to lateral limbus distance in both sexes. Between MI and MC the difference was insignificant for interbrow distance in male groups, apex to lateral limbus distance in females, and palpebral fissure inclination and eyebrow apex angle in both sexes. Between MM and MC, significant differences were found for eyebrow thickness and medial canthus tilt in female group. Male groups showed significant difference for apex to lateral limbus and lateral canthus distance and eyebrow apex angle. Eyebrow height, palpebral fissure width, and intercanthal distance were significantly different in both sexes. Sexual dimorphism was found for all measurements in MI, but MM and MC showed insignificant difference for eyebrow apex angle. Four types of epicanthus were observed in MM and MC and three types in MI. Eyebrow apex between lateral limbus and lateral canthus was the most common position in all racial groups. Significant racial and gender differences exist for certain periorbital measurements. The knowledge of these differences is expected to influence the surgical outcome.

Matched MeSH terms: Sex Characteristics; Sex Factors
Fulltext Perceptions of Stalking: Examining Perceivers' Country of Origin, Perpetrator-Target Prior Relationship, and the Mediating Effect of Victim Responsibility

Chung KL, Sheridan L

J Interpers Violence, 2022 Nov;37(21-22):NP19644-NP19663.
PMID: 34490815 DOI: 10.1177/08862605211042601

Research in stalking perceptions has shown certain relational biases, in which people tend to view ex-partner stalkers to be less dangerous than stranger or acquaintance stalkers. These findings are in direct contrast to those of real-life cases whereby ex-partner stalkers pose a greater threat. In addition, although stalking is recognized as a global social problem, most studies have been based on samples drawn from Western, educated, industrialized, rich, and democratic countries. The current study examined whether the prior relationship between the stalking perpetrator and target influences people's perceptions of stalking and whether cross-national differences exist between participants based in Malaysia (where there is currently no law that criminalizes stalking) and England (where stalking has been outlawed since 1997). In a 3 × 2 between-subjects design, 294 Malaysian participants and 170 English participants were presented with a vignette describing a stalking scenario in which the perpetrator was depicted as a stranger, acquaintance, or ex-partner. Participants judged the extent to which the perpetrator's behavior constitutes stalking; necessitates police intervention; would cause the victim alarm or personal distress; would cause the victim to fear the use of violence; and can be attributed to encouragement on the part of the victim. Results showed that typical relational biases existed in both samples, but Malaysian participants were less likely than their English counterparts to label any harassing scenario as serious. Perceptions of victim responsibility were found to mediate the effect of prior relationship and nationality on participants' perceptions. The findings point to the urgency of better cross-cultural understanding of harassment behavior as well as legislations against stalking.

Matched MeSH terms: Sex Offenses*
Fulltext REPLY BY THE AUTHORS: Re: Persistent Mullerian Duct Syndrome: a rare entity with a rare presentation in need of multidisciplinary management

Aw LD, Zain MM, Esteves SC, Humaidan P

Int Braz J Urol, 2017 Sep-Oct;43(5):1005-1006.
PMID: 28792190 DOI: 10.1590/S1677-5538.IBJU.2017.0072.1
Matched MeSH terms: 46, XY Disorders of Sex Development*
Fulltext Sexual dimorphism in shell size of the land snail Leptopoma perlucidum (Caenogastropoda: Cyclophoridae)

Phung CC, Choo MH, Liew TS

PeerJ, 2022;10:e13501.
PMID: 35651743 DOI: 10.7717/peerj.13501

Sexual dimorphism in the shell size and shape of land snails has been less explored compared to that of other marine and freshwater snail taxa. This study examined the differences in shell size and shape across both sexes of Leptopoma perlucidum land snails. We collected 84 land snails of both sexes from two isolated populations on two islands off Borneo. A total of five shell size variables were measured: (1) shell height, (2) shell width, (3) shell spire height, (4) aperture height, and (5) aperture width. We performed frequentist and Bayesian t-tests to determine if there was a significant difference between the two sexes of L. perlucidum on each of the five shell measurements. Additionally, the shell shape was quantified based on nine landmark points using the geometric morphometric approach. We used generalised Procrustes and principal component analyses to test the effects of sex and location on shell shape. The results showed that female shells were larger than male shells across all five measurements (all with p-values < 0.05), but particularly in regards to shell height and shell width. Future taxonomic studies looking to resolve the Leptopoma species' status should consider the variability of shell size caused by sexual dimorphism.

Matched MeSH terms: Sex Characteristics*
Sex estimation in the South-East Asian population: A systematic review

Saad S, Hisham S, Amir Hamzah SPA

Malays J Pathol, 2024 Apr;46(1):21-40.
PMID: 38682842

INTRODUCTION: Sex estimation is crucial in forensic anthropology. In situations such as mass disasters, and forensic anthropology cases, sex estimation is a very important initial step in the disaster victim identification process. Literature has acknowledged that sex estimation is population-specific. However, sex estimation standards in South-East Asian populations are limited, leading to the usage of most Thais discriminant function equations on sex estimation by other South-East Asian countries including Malaysia. This systematic review was conducted to summarise the findings of sex estimation studies in South-East Asian countries.
MATERIALS AND METHODS: A systematic literature search was performed through the SCOPUS database and Web of Science (WOS) database for relevant studies between 2014 and 2022. All published articles that are related to sex estimation from different types of bone, methods, landmarks, and sample sources (i.e., photographs, dry bones, and CT images) were included in this review. The main inclusion criteria were studies on (i) sex estimation; (ii) in South-East Asian populations; (iii) between the years 2014 and 2022; and (iv) in English.
RESULTS: The literature search identified 30 potentially relevant studies, of which 15 publications met all the inclusion criteria. From those research, 13 studies were related to the Thai population and two to the Malaysian population. Only one study was based on morphological traits, while the rest were based on a morphometric approach.
CONCLUSION: All studies found that sex estimation is populationspecific. Therefore, further research is recommended to explore more on population-specific sex estimation using different parts of bone.

Matched MeSH terms: Sex Determination by Skeleton/methods
Sex Differences in Mate Preferences Across 45 Countries: A Large-Scale Replication

Walter KV, Conroy-Beam D, Buss DM, Asao K, Sorokowska A, Sorokowski P, et al.

Psychol Sci, 2020 Apr;31(4):408-423.
PMID: 32196435 DOI: 10.1177/0956797620904154

Considerable research has examined human mate preferences across cultures, finding universal sex differences in preferences for attractiveness and resources as well as sources of systematic cultural variation. Two competing perspectives-an evolutionary psychological perspective and a biosocial role perspective-offer alternative explanations for these findings. However, the original data on which each perspective relies are decades old, and the literature is fraught with conflicting methods, analyses, results, and conclusions. Using a new 45-country sample (N = 14,399), we attempted to replicate classic studies and test both the evolutionary and biosocial role perspectives. Support for universal sex differences in preferences remains robust: Men, more than women, prefer attractive, young mates, and women, more than men, prefer older mates with financial prospects. Cross-culturally, both sexes have mates closer to their own ages as gender equality increases. Beyond age of partner, neither pathogen prevalence nor gender equality robustly predicted sex differences or preferences across countries.

Matched MeSH terms: Sex Characteristics*
Cytogenetics of ticks (Acari: Ixodoidea). 14. Chromosomes of nine species of Asian haemaphysalines

Oliver JH, Tanaka K, Sawada M

Chromosoma, 1974 May 10;45(4):445-56.
PMID: 4837734
Matched MeSH terms: Sex Chromosomes; Sex Determination Analysis

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