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  1. Lee PM, Chang CT, Yusoff ZM
    Int J Clin Pharm, 2021 Feb;43(1):46-54.
    PMID: 32524510 DOI: 10.1007/s11096-020-01070-9
    Background Tyrosine kinase inhibitors have been demonstrated to improve the survival of patients with chronic myeloid leukaemia. However, medication adherence is vital for patients on chronic treatment. Objective The objective of the current study was to evaluate response to treatment, adherence by patients to tyrosine kinase inhibitors and factors associated with adherence and response. Setting A haematology clinic in a regional referral hospital in Malaysia. Method Patients aged ≥ 13 years who had been on imatinib or nilotinib for ≥ 12 months were included in this cross-sectional study. An optimal response was defined as the achievement of major molecular response at 12 months of treatment. Patient medication adherence was determined using the average medication possession ratio based on the dispensing records. The patients were considered adherent if the medication possession ratio was > 90%. Multiple logistic regression was performed to evaluate the factors associated with adherence. The association of adherence with molecular response was analysed by univariate logistic regression. Main outcome measure The primary outcome measures were the proportion of patients who achieved optimal response and the medication possession ratio. Results A total of 151 patients were screened, and 71 patients were included. Twenty-eight patients (39%) achieved major molecular response at 12 months of treatment. The median time to achieve this was 15.5 months (an interquartile range of 15). The mean medication possession ratio for imatinib and nilotinib was 0.94 (± 0.14) and 0.96 (± 0.10), respectively, but this difference was without statistical significance (t  =  - 0.517, p  =  0.610). Nausea and vomiting (odds ratio [OR] of 0.25, 95% confidence interval [CI]: 0.07-0.83, p  =  0.023) and disease phase at diagnosis (OR of 0.20, 95% CI 0.04-1.06, p  =  0.059) were associated with patient adherence. An association was not found between patient adherence and molecular response (OR of 1.03, 95% CI 0.35-3.09, p  =  0.956). Conclusion The patients in this study demonstrated a relatively deep molecular response and optimal adherence. Nevertheless, one fourth of them were noncompliant with imatinib. Therefore, active interventions are warranted to prevent treatment-associated adverse events and improve adherence.
    Matched MeSH terms: Cross-Sectional Studies
  2. Pasyar N, Rambod M, Behrouzi Z
    Malays J Med Sci, 2020 May;27(3):75-83.
    PMID: 32684808 DOI: 10.21315/mjms2020.27.3.8
    Background: Thalassemia is a prevalent chronic blood disorder, which is accompanied with a wide range of challenges. This study aimed to determine the predictor role of perceived social support and spiritual intelligence in hope among thalassemia patients.

    Methods: This cross-sectional study was conducted on 300 thalassemia patients. The data were collected using Miller hope scale, spiritual intelligence scale, and personal resource questionnaire. The data were analysed using Pearson's correlation coefficient and multiple regression analysis.

    Results: The results indicated that the mean score of hope was 173.38 (standard deviation [SD] = 24.6). Besides, 86.7% of the patients showed high levels of hope. The mean score of spiritual intelligence was 134.66 (SD = 18.07). In addition, 91.7% of the patients showed moderate levels of spiritual intelligence. The mean score of social support was 127.87 (SD = 20.19) and the patients showed high social support levels. The results revealed a significant association between hope and perceived social support (r = 0.65, P < 0.001) as well as between hope and spiritual intelligence (r = 0.63, P < 0.001). Moreover, perceived social support (b = 0.43, P < 0.001) and spiritual intelligence (b = 0.37, P < 0.001) were the predictors of hope among thalassemia patients.

    Conclusion: Considering the study results, in addition to common treatments for thalassemia, policymakers' are recommended to pay attention to spiritual intelligence and more importantly social support to enhance thalassemia patients' hope.

    Matched MeSH terms: Cross-Sectional Studies
  3. Ismail N, Khalid MKA
    MyJurnal
    Adjustment among new students at the university plays an important role in determining their success at university. This study showed one of the reasons students fail to complete their study is due to adjustment problems. Students found to be unable to deal with the challenges and demands on campus and experience a variety of problems that some of them failed to proceed to the next semester. The population of the study consist of 143 First Semester Diploma students in the Faculty of Business and Management studies at Universiti Teknologi MARA Pahang Raub Campus. The instrument used is questionnaires. There are four subscales designed to measure the effectiveness of student adjustment to university that are academic adjustment, social adjustment, personal (emotional) adjustment and institutional commitment. The study shows that adaptability on campus has a relationship with psychosocial abilities possessed by the students. Among the psychosocial abilities have a positive and significant impact on student adjustment is emotional intelligence, coping, and social support. All three of these psychosocial capabilities found to play an important role in helping students adjust at the university. Thus, the university must take proactive steps to develop emotional intelligence, coping and social support among new students to improve their adaptability
    Matched MeSH terms: Cross-Sectional Studies
  4. Rizky M, Isa MM, Kamarlis RK
    Med J Malaysia, 2020 05;75(Suppl 1):37-40.
    PMID: 32471967
    INTRODUCTION: Hirschsprung's Disease (HD) also called congenital aganglionic megacolon is a disorder caused by undeveloped distal to proximal intestinal nerve ganglion cells. Diagnosis includes determining the aganglionic segment through barium enema radiology examination and histopathology of frozen section with permanent section as gold standard. Determining the diagnostic value of this modality is important for operative management decision.

    MATERIALS AND METHODS: The study was a retrospective, cross-sectional study with diagnostic test design. Patient data were obtained in the form of clinical symptoms, barium enema, and frozen section expertise were assessed for the suitability of the diagnostic value by referring to the permanent section as the gold standard.

    RESULT: Thirty-four patient data were obtained. The sensitivity, specificity, and accuracy of barium enemas were 95%, 69.2%, and 82%, respectively. The values of sensitivity, specificity, and accuracy of frozen section were 95%, 92.8%, and 88%, respectively. The Cohen-Kappa statistic value was 0.62 (good agreement).

    CONCLUSION: Accuracy of FS is better than barium enema in diagnosing HD. In health care center with limitation of histopathological facility, BE could be used as the alternative procedure as interrater comparisons showed good agreement. Therefore, either frozen section or barium enema can be carried out in common or in separate term.

    Matched MeSH terms: Cross-Sectional Studies
  5. Ahmad NI, Yean Yean C, Foo PC, Mohamad Safiee AW, Hassan SA
    J Infect Public Health, 2020 Oct;13(10):1508-1512.
    PMID: 32653480 DOI: 10.1016/j.jiph.2020.06.018
    BACKGROUND: Panton-Valentine Leukocidin (PVL), is one of the virulence gene expressed by Methicillin Resistant Staphylococcus aureus (MRSA) and is known to be associated with severe form of community acquired MRSA infection. The aim of this study is to investigate its prevalence in our setting and patient's clinical outcome.

    METHODS: A cross sectional study involve retrospective record review were done involving 90 MRSA positive isolates between November 2016 and October 2017. Multiplex PCR was performed to detect femA, mecA and PVL genes. Clinical presentation and outcomes of patients were reviewed and presented as descriptive analysis.

    RESULTS: All of the 90 MRSA isolates included in this study were positive for femA and mecA genes following PCR. PVL gene was detected in 20% (n = 18) of the isolates of which 61.1% (n = 11) were community acquired infections and 38.8% (n = 7) were hospital acquired. Case distribution from community acquired infections include patients with skin and soft tissue infections (33.3%, n = 6), infected diabetic foot ulcers (16.7%, n = 3), and one patient each (5.5%, n = 1) for community acquired pneumonia and meningitis. Half of the PVL positive MRSA cases (50%, n = 9) were having sepsis and four of them succumbed to death due to severe infection.

    CONCLUSION: This study shows a high prevalence of PVL positive MRSA infection in our population. Skin and soft tissue infections accounting for the major sources. In addition, the presence of the PVL gene is associated with increased risk for developing sepsis.

    Matched MeSH terms: Cross-Sectional Studies
  6. Koh CJ, Lakhtakia S, Kida M, Lesmana CRA, Ang TL, Vu CKF, et al.
    Endoscopy, 2021 06;53(6):595-602.
    PMID: 32650341 DOI: 10.1055/a-1217-3112
    BACKGROUND: Although endoscopic ultrasound (EUS) features and criteria have been described in chronic pancreatitis, challenges remain with interoperator variability and ease of adoption. The aim of this study was to define and validate the EUS features of chronic pancreatitis in a multicenter prospective study in Asia.

    METHOD: The study was divided into two parts: the first part was conducted to derive the EUS features of chronic pancreatitis with adequate interoperator agreement; the second was to prospectively evaluate these features in a multicenter cross-sectional study and determine the optimal combination of features for the diagnosis of chronic pancreatitis. Prospectively enrolled cases had standard internationally validated radiologic or histologic features of chronic pancreatitis, and controls were patients without chronic pancreatitis who underwent EUS examination.

    RESULTS: The top six EUS features that had good interobserver agreement (mean kappa 0.73, range 0.60 - 0.90) were selected to be further evaluated in part II of the study. These included: hyperechoic foci with shadowing, lobularity with honeycombing, cysts, dilated main pancreatic duct, dilated side branches, and calculi in the main pancreatic duct. A total of 284 subjects (132 cases, 152 controls) were enrolled from 12 centers in Asia. All six features had high accuracy ranging from 63.3 % to 89.1 %. Two or more of these six EUS features accurately defined chronic pancreatitis (sensitivity 94.7 %, specificity 98.0 %), with an area under the receiver operating curve of 0.986.

    CONCLUSION: This multicenter Asian study characterized and defined the EUS features of chronic pancreatitis. This provides a useful tool in clinical practice and further research in pancreatic cancer surveillance.

    Matched MeSH terms: Cross-Sectional Studies
  7. Harapan H, Wagner AL, Yufika A, Winardi W, Anwar S, Gan AK, et al.
    Front Public Health, 2020;8:381.
    PMID: 32760691 DOI: 10.3389/fpubh.2020.00381
    Introduction: Several vaccine candidates are being clinically tested in response to the 2019 coronavirus disease (COVID-19) pandemic. This study was conducted to assess the acceptance of a 50 or 95% effective COVID-19 vaccine, when it becomes available in southeast Asia, among the general population in Indonesia. Methods: A cross-sectional online survey was conducted between March 25 and April 6, 2020. Participants were asked if they would accept a free vaccine which was 95 or 50% effective. Using a logistic regression model, we assessed the associations between sociodemographic characteristics, exposure to COVID-19 information, or perceived risk of infection with acceptance of a hypothetical COVID-19 vaccine. Results: Among 1,359 respondents, 93.3% of respondents (1,268/1,359) would like to be vaccinated for a 95% effective vaccine, but this acceptance decreased to 67.0% (911/1,359) for a vaccine with 50% effectiveness. For a 95% effective vaccine, being a healthcare worker and having a higher perceived risk of COVID-19 infection were associated with higher acceptance, adjusted odds ratio (aOR): 2.01; 95%CI: 1.01, 4.00 and aOR: 2.21; 95%CI: 1.07, 4.59, respectively; compared to civil servants, being retired was associated with less acceptance (aOR: 0.15; 95%CI: 0.04, 0.63). For a 50% effective vaccine, being a healthcare worker was also associated with greater acceptance, aOR: 1.57; 95%CI: 1.12, 2.20. Conclusion: Acceptance of a COVID-19 vaccine was highly influenced by the baseline effectiveness of the vaccine. Preparing the general population to accept a vaccine with relatively low effectiveness may be difficult.
    Matched MeSH terms: Cross-Sectional Studies
  8. Lazim NM, Abdullah AM, Abdullah B, Ismail ZIM
    Medeni Med J, 2019;34(4):333-339.
    PMID: 32821458 DOI: 10.5222/MMJ.2019.25986
    Objective: The aim of the study was to determine the association of angulation of nasal septum with the severity of rhinosinusitis as measured by symptom score and Visual Analog Score (VAS).

    Method: The study was performed as a cross sectional study conducted at two different centres in Malaysia. Ninety-eight patients who were diagnosed with rhinosinusitis and fulfilled the selection criteria were assessed as for the symptom score and VAS and the measurement of angulation of nasal septum was performed through a coronal view of CT paranasal sinuses in bone window setting at osteomeatal complex level.

    Results: The result obtained from one-way ANOVA test revealed a significant association between category of severity of septal angulation and the symptom score of rhinosinusitis (p=0.025). In addition, the result obtained from one-way ANOVA test also revealed a significant association between category of severity of septal angulation and the VAS of rhinosinusitis (p<0.05).

    Conclusion: Severity of nasal septum angulation may be significantly associated with severity of rhinosinusitis based on symptom score and VAS. These findings could be used in tailored management of patient with rhinosinusitis especially during functional endoscopic sinus surgery.

    Matched MeSH terms: Cross-Sectional Studies
  9. Binti Shuhairi NN, Bt Abdul Jalil A, Lau SH, Bt Mohd Ghazali S, Kee CC
    Int J Paediatr Dent, 2021 Jul;31(4):496-503.
    PMID: 32815206 DOI: 10.1111/ipd.12719
    BACKGROUND: Globally, research on oral and maxillofacial lesions among newborns and infants remains limited.

    AIM: To describe demographic patterns, histopathological findings, and locations of oral and maxillofacial lesions in newborns (birth-1 month) and infants (>1 month-2 years) reported over 51 years.

    DESIGN: A retrospective cross-sectional study on histopathological records of newborns and infants was conducted. Patients' demographic characteristics (age, gender, and race), histopathological diagnosis, and lesion's location were gathered. Pearson's chi-square or Fisher's exact test was performed to determine associations between demographic characteristics and different categories of lesions.

    RESULTS: Out of 66,546 specimens received, 0.44% (290 specimens) were from patients aged 2 years and younger (27 newborns and 263 infants). The most common category was inflammatory/reactive (44.2%), followed by tumour/tumour-like (42.0%), cystic/pseudocystic (6.6%), and miscellaneous lesions (5.5%). Mucous extravasation cysts (23.4%) and Langerhans cell histiocytosis (7.2%) were the most common histopathological diagnoses. Tumour/tumour-like lesions were significant in newborns (P = .021), and majority were congenital epulis (40.7%). Inflammatory/reactive lesions were significantly higher in male (P = .025) and infants (P = 

    Matched MeSH terms: Cross-Sectional Studies
  10. De Meester A, Wazir MRWN, Lenoir M, Bardid F
    Res Q Exerc Sport, 2020 Sep 09.
    PMID: 32903170 DOI: 10.1080/02701367.2020.1788700
    Purpose: The present study examined whether groups of children with different physical fitness and fitness enjoyment profiles could be identified and, if so, whether the different groups varied from one another in terms of organized sports participation. Method: Five hundred and fifty-eight 8-11-year-olds (56.99% boys) participated in this cross-sectional study. Physical fitness and fitness enjoyment were assessed with seven items from a standardized test battery and a pictorial scale containing pictures referring to the enjoyment in those seven physical fitness tests, respectively. To examine whether groups with different fitness and enjoyment profiles could be identified, we conducted cluster analyses based on children's standardized physical fitness and fitness enjoyment scores. A two-way ANCOVA (sex*cluster) was conducted to investigate differences in weekly organized sports participation among each of the identified groups while controlling for age. Results: Cluster analyses revealed two groups with aligned levels of physical fitness and fitness enjoyment (i.e., relatively low-low and relatively high-high) and two groups with unaligned levels (i.e., relatively low-moderate and relatively high-moderate), respectively. Both groups with relatively high fitness scores were found to spend significantly more time in organized sports (M = 2.01 h and 2.29 h, respectively) than the two groups with relatively low fitness scores (M = 1.08 h and 0.98 h, respectively), irrespective of their enjoyment levels. Conclusion: Increasing physical fitness levels (especially among those children with suboptimal enjoyment levels) may lead to increased organized sports participation, while increased organized sports participation in its turn may lead to higher fitness levels. As such, participation in sports programs should be promoted in children of all age groups.
    Matched MeSH terms: Cross-Sectional Studies
  11. Nur Fadzlina Zulkefli, Muhammad Muzaffar Ali Khan Khattak, Wan Azdie Mohd Abu Bakar
    MyJurnal
    The aim of this study was to assess picky eating behavior existence among university students. This was an observational cross sectional study design. The sample size was calculated by using single proportion formula based on the adult prevalence of picky eating of 28.7 % which gives a sample of ~ 324 students. However, 407 students online registered to participate out which 403 students responded. A set of questionnaire was posted online. The questionnaire contained three sections which are demographic information, determinants of picky eating behavior and normal eating behaviors. Furthermore, the students were categorized as non-picky eating behavior, moderate picky eating behavior, and extreme picky eating behavior. The statistical analysis
    carried out was mainly descriptive in order to determine the extent of picky eating behavior among the university students. Student t-test was used to find the differences between picky and non-picky eaters in terms of eating behaviors. Among the students possessing non picky eating behavior, moderate picky eating behavior and extreme picky eating behavior were 168 (41.69%), were 130(32.26%), 105(26.05%) respectively. On overall basis 235(58.31 %) of the students were having picky eating behavior. The present study revealed that picky eating behavior exists among the university students which need to be addressed.
    Matched MeSH terms: Cross-Sectional Studies
  12. Ibrahim Alzamel LG, Abdullah KL, Chong MC, Chua YP
    J Egypt Public Health Assoc, 2020 Aug 14;95(1):20.
    PMID: 32813099 DOI: 10.1186/s42506-020-00048-9
    BACKGROUND: Understanding the factors influencing nurses' turnover intention, particularly the work life quality and commitment to organization, is important to all countries suffering from nursing shortage. The study aims to determine the mediating role of commitment to organization on work life quality and its relationship with turnover intention among Malaysian nurses.

    METHODS: A descriptive cross-sectional design, using a self-report survey was conducted on 430 nurses from a teaching hospital from February to April 2019. A structural equation model version 3 was used for testing study hypotheses.

    RESULTS: The mediating effect (indirect effect) of organizational commitment on the relationship between work life quality and turnover intention (QWL→OC→IT) was negative with path coefficient - 0.234, whereas the direct effect of work life quality on turnover intention (QWL→IT) was negative with smaller path coefficient - 0.228. This means that the relationship between work life quality and turnover intention was partially mediated by the organizational commitment (P < 0.001).

    CONCLUSION: Organizational commitment has a negative partial mediating effect between work life quality of nurses and intention of turnover in teaching hospitals where the organizational commitment significantly reduced the nurses' intention to leave. The study findings can guide nursing managers to be carefully attended to the levels of nurses' commitment to their organization.

    Matched MeSH terms: Cross-Sectional Studies
  13. Yahya AN, Sit JA, Raman S
    MyJurnal
    The success of cataract surgery is accessed by the improvement in visual acuity and accuracy of the post-operation refractive outcome against the pre-operation refractive target. Hence, the benchmark of 85% of patients achieving a final spherical equivalent within 1D of the desired target is used to monitor the refractive outcome. Meanwhile, the unaided visual acuity threshold of 6/12 after cataract operation is chosen as a yardstick because it allows patients to perform instrumental activities of daily living (IADL) independently without relying on spectacles.
    Matched MeSH terms: Cross-Sectional Studies
  14. Valentine J G, Diane C, Chua Y W
    MyJurnal
    Men who have sex with men (MSM) is one of the key populations affected by HIV epidemic with infection rates exceeding five percentages. Due to a strict and prohibitive socio-cultural and legal environment, male-to-male sexual practices are often misunderstood and highly stigmatised, thus creating barriers for MSM to access HIV prevention, treatment, care and support services.
    Matched MeSH terms: Cross-Sectional Studies
  15. Umar B, Alam MM, Al-Amin AQ
    Environ Sci Pollut Res Int, 2021 Jan;28(2):1973-1982.
    PMID: 32862348 DOI: 10.1007/s11356-020-10641-2
    The increasing level of greenhouse gas carbon emission currently exacerbates the devastating effect of global warming on the Earth's ecosystem. Energy usage is one of the most important determinants that is increasing the amount of carbon gases being released. Simultaneously, the level of energy usage is derived by the price, and therefore, this study examines the contribution of energy price to carbon gas emissions in thirteen African nations for the period spanning 1990 to 2017. It does this by utilising the cross-sectional dependence (CD), augmented mean group (AMG) and pooled mean group (PMG) panel modelling methods. The findings of the AMG model suggest that a 1% increase in energy price leads to a 0.02% decrease in carbon emission. The results further reveal that a 1% increase in energy intensity and technological innovation leads to 0.04% and 3.65% increase in carbon emission, respectively, in the selected African countries. Findings will help policymakers to implement effective energy price policies to reduce carbon emissions and achieve sustainable development goals especially in the emerging economies of Africa.
    Matched MeSH terms: Cross-Sectional Studies
  16. Mohd Ferous Alias, Yusof Ibrahim
    MyJurnal
    Introduction: Clinical wastes produced by health facilities were considered as scheduled waste listed in the First Scheduled of the Environmental Quality (Scheduled Waste) Regulation 1989. The management of clinical waste in all government hospitals in Sabah were outsourced to private concession company. Until now, there was no research being done in Sabah to evaluate it. Methods: This cross-sectional study was carried out on eight concessionaire com-panies located inside accredited non-specialist government hospitals in West Coast Division & Interior Division of Sabah. Data collected through Clinical Waste Management (CWM) Scores and Questionnaires. CWM scores adopt 5 elements of accreditation standard produced by Malaysian Society Quality in Health (MSQH). Questionnaires were used to collect concessionaire staff’s basic personal data, services and activities related to clinical wastes ac-cording to MSQH standard. Response from questionnaires were used to compare and support result gained from CWM scores. Descriptive analysis was used to analyze the data. Results: Two concessionaire companies got overall CWM scores ranging between 86% - 90%, while the other six companies were above 95%. It happened because both companies gained 81% and 73.3% on Policies and Procedures element. Result from questionnaires answered by 67 concessionaire staffs showed 98% of staffs had attended meeting, 97% had received an orientation, 97% had received training related to clinical wastes, 95% agreed that their work was monitored and no occupational disease and injury recorded between January to April 2019. These result correlate with CWM scores gained under Orga-nization Management element (99.6%), Human Resource Management element (90.1%), Facilities and equipment element (97%) and Safety & Quality Improvement element (100%). Conclusions: All concessionaire companies were implementing excellent clinical waste management in hospitals. CWM scores can be used to rank individual conces-sionaire company and provide pattern of uniformity or non-uniformity of the clinical waste management in Sabah.
    Matched MeSH terms: Cross-Sectional Studies
  17. James Yau Hon Voo, Baharudin Ibrahim, Mohamed Azmi Hassali, Foong Ming Moy
    MyJurnal
    Introduction: There has been a resurgence of vaccine-preventable diseases in Malaysia over the recent years. In overcoming this issue, parents as the main caregiver of their children play a major role, which is to protect their children against diseases via vaccinations. This study aimed to examine the parents’ vaccine knowledge, aware-ness, and hesitancy in relation to their children’s immunisation status and to determine the association between the parents’ vaccine knowledge, awareness, and hesitancy. Methods: A cross-sectional study with a sample size of 405 parents was conducted in the Sandakan health clinics from February 2018 to April 2018 by employing validated questionnaires adapted from two studies. Results: The median ± IQR of the total vaccine knowledge and awareness scores (ranging from 0-10) were 7.00±3.00 and 8.00±4.00, respectively. Meanwhile, the median ± IQR of the total vaccine hesitancy scores (ranging from 0-100) was 16.67±20.00, with only 27 (6.8%) parents being vaccine-hesitant (scores >50). Most of the children (n=376, 92.8%) were immunised in the study. It observed a significant association between the children’s immunisation status and the parents’ vaccine knowledge scores (p = 0.005). Nevertheless, the children’s immunisation status was not significantly associated with the parents’ vaccine awareness and hesitancy scores. The positive Spearman correlation value (r = 0.551) signified that the parents’ vaccine knowledge was posi-tively associated with their vaccine awareness. On the other hand, both the vaccine knowledge and awareness were negatively correlated to the vaccine hesitancy as indicated by the negative Spearman correlation value (r = -0.397 and r = -0.351 respectively). Conclusion: The study established that the parents with a better understanding about vaccinations were more likely to keep their children’s immunisation up-to-date. It was also revealed that improving the parents’ knowledge and raising their awareness about the importance of vaccination are vital in reducing their vaccine hesitancy.
    Matched MeSH terms: Cross-Sectional Studies
  18. Raihanah Chokeli, Nur Azira Baharuddin, Vivien How, Nurul Syazani Yuswir, Shariza Afini Mohd Noor, Ho Yu Bin, et al.
    MyJurnal
    Introduction: The increased use of mobile phones has increased the mobile base stations (MBS) deployment. While understanding of radiation protection is growing among the public, questions regarding early-life exposure to ra- diofrequency radiation (RFR) from MBS in children are of importance as to whether it will raise the chances of developing chronic diseases during adulthood. Taking into account the sitting location of MBS, the purpose of this study is to evaluate the chromosomal DNA damage in buccal mucosal cells between school children exposed to RFR emitted from base station antennas. Method: This is a comparative cross-sectional study in which two group of school children were sampled i.e. exposed groups are children whose school located near MBS (200 meters); un- exposed groups are children whose school located distant far from the MBS (>200 meters). Digital RF Analyzer was used to measure RFR at the school surrounding. Buccal mucosa cells from the oral cavity were sampled to examine the level of micronuclei (MN) frequencies. Results: This study found that the densities of the RFR energy differed in range. Although all measurements showed the RFR reading below the acceptable exposure level, there were still sig- nificant variations at each location assessed. Statistically, the MN frequency is significantly different when compared to the exposed and non-exposed group. Conclusion: To understand the mechanism of health effects from exposure to low-level RFR emited from MBS, further study should consider environmental factors influencing MBS sitting on RFR emission, as well as examining the health effects into molecular levels.
    Matched MeSH terms: Cross-Sectional Studies
  19. Nurul Maizura Hashim, Zailina Hashim, Rukman Awang Hamat, Hayati Kadir
    MyJurnal
    Introduction: Water based Metalworking fluids (MWF) are commonly used in machining industries and are excellent media for microorganism growth. The study aimed at determining the relationship between the airway inflammation as indicated by fractional exhaled nitric oxide (FeNO) with the microbial contaminants of MWF in aerosol and bulk sample as well as the workers’ reported respiratory health symptoms. Methods: This cross sectional study was carried out on 138 machining workers. Their FeNO were measured using NIOX-MINO instrumentation. The microbial as- sessments of bacteria and fungus were carried out on the MWF bulk samples and the aerosol using a sampler DUO SAS SUPER 360TM. Results: Findings showed significant difference in the FeNO levels in workers from various job sections (p=0.01). Significant relationships found between high FeNO levels with their closeness to the machines (p=0.03), high number of machines in the workplaces (p=0.02), high environmental bacteria colonies (p=0.04), lon- ger employment years (p
    Matched MeSH terms: Cross-Sectional Studies
  20. Ahmad Syaify B., Alamin M. D., Norafidah A. R.
    MyJurnal
    Introduction:Lymphatic filariasis (LF) is a neglected tropical disease that can cause significant morbidity. In Malay-sia, National Programme for the Elimination of Lymphatic Filariasis started in 2001 with the initial target of achiev-ing Lymphatic Filariasis elimination status by 2018 but it has been revised to year 2020. Mass Drug Administration (MDA) Programme was performed from 2004 to 2008 in all endemic areas (Red Implementation Unit, IU) in Malay-sia including Terengganu state to stop disease transmission. Transmission Assessment Surveys (TAS) were conducted later on and for Terengganu, they were done in 2011 (TAS 1), 2015 (TAS 2) and 2017 (TAS 3) and had passed all the surveys based on critical cut off (CCO) point given. Methods: A cross sectional analysis of 10-year Terengganu filariasis records (2009-2018) was initiated in June 2019 using data source from eVekpro and filariasis cases line-list-ing. Results: Majority of filariasis cases in Terengganu were among males (n=147, 76.6%) with the highest number among 30-39 year-old age group (n=35, 18.2%). Majority of cases were Malaysian citizens (n=162, 84.4%) with main filariasis species identified were Brugia Malayi (n=149, 77.6%). The number of cases diagnosed was slightly higher from Green Implementation Unit area (n=102, 53.1%) compared to Red Implementation Unit area. Conclu-sion: The number of lymphatic filariasis cases among Terengganu citizens was below critical cut off point after the accomplishment of MDA programme and in accordance with the aim of lymphatic filariasis elimination status in Malaysia by 2020.
    Matched MeSH terms: Cross-Sectional Studies
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