Displaying publications 61 - 80 of 96 in total

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  1. Yaacob HB, Ling BC
    Med J Malaysia, 1981 Jun;36(2):83-6.
    PMID: 7343824
    Fifty patients with temporomandibular pain dysfunction syndrome were examined. Seventy-eight percent and 32 percent were female and male respectively. The white collar workers were more frequently affected. Emotional stress, dental malocclusion and a history of trauma were the main causes. Treatment consists of reassurance, relaxed jaw movements and exercises, anxiolytic drugs, thermotherapy, biting appliance, occlusal adjustments and restoration oflost dental units.
    Matched MeSH terms: Malocclusion/complications
  2. Meon R, Majid ZA, Salcedo AH
    Singapore Dent J, 1987 Dec;12(1):75-8.
    PMID: 3509314
    Matched MeSH terms: Malocclusion/epidemiology
  3. Fathinah Hanem Azamzaki, Nurhanis Baharuddin, Tandon, Shobha, Venkiteswaran, Annapurny
    Compendium of Oral Science, 2018;5(1):18-25.
    MyJurnal
    Objectives:To determine the different occlusal characteristics in primary dentition of 3 to 6 year old Malay children and to create a preliminary database for future Malaysian studies as currently none of the studies has been conducted in Malaysian population regarding the occlusal features in primary dentition. Materials and method:The subjects were within the age ranging from 3 – 6 years old attending nurseries and kindergartens located within Sungai Buloh, Selangor. Sixty subjects were screened but only 47 fulfilled the criteria to be included in this study. Intra-oral examination was done to determine the terminal plane, canine relationship, overjet, overbite and primate space in the subjects. Results: Almost two thirds of the subjects (72.34%) presented with straight terminal plane. All but one subject were observed with Class I canine relationship. 61.7% subjects were with an ideal overjet and 53.19% of subjects had an ideal overbite. The mean value for primate space in the maxilla was 2.92mm and 1.60mm in the mandible. There was no significant difference between gender in all the parameters assessed. Conclusion: The results from the study shown that only few of the subjects had a tendency of malocclusion in their permanent dentition. However, a longitudinal study should be done to follow up their occlusal feature in the permanent dentition.
    Matched MeSH terms: Malocclusion; Malocclusion, Angle Class II
  4. Fareen N, Alam MK, Khamis MF, Mokhtar N
    Int J Pediatr Otorhinolaryngol, 2019 Oct;125:159-163.
    PMID: 31323354 DOI: 10.1016/j.ijporl.2019.07.008
    BACKGROUND: Treatment of Class III malocclusion is related to redirecting the growth of mandible, which may have an impact on the pharyngeal airway.

    OBJECTIVE: To evaluate and compare the treatment effect of Reverse Twin-Block (RTB) and Reverse Pull Face Mask (RPFM) on Pharyngeal Airway Space (PAS) in early and late mixed dentition Class III samples.

    METHODS: Ninety-five mixed dentition Malay children with Class III malocclusion were included in this study. Data consists of 190 pre- and post-treatment lateral cephalograms of early (8-9 years) and late (10-11 years) mixed dentition Class III samples. forty-nine samples were under RTB and forty-six samples were under RPFM. Treatment changes were evaluated by McNamara airway analysis and changes in tongue and hyoid bone position.

    RESULTS: Both upper and lower pharyngeal airway width were increased after treatment with RTB and RPFM ruling out the chance of airway constriction. There was also posterior positioning of the tongue and hyoid bone indicating mandibular retrusion. No significant treatment changes were found on the Pharyngeal Airway Space by the factor age, gender or type of appliance.

    CONCLUSIONS: Both RTB and RPFM increased the Pharyngeal Airway Space and produced similar treatment effect. As age does not affect the treatment outcome significantly, treatment can be delayed until late mixed dentition stage.

    Matched MeSH terms: Malocclusion, Angle Class III/therapy*
  5. Haque S, Alam MK, Khamis MF
    Cleft Palate Craniofac J, 2018 08;55(7):966-973.
    PMID: 27479096 DOI: 10.1597/15-293
    OBJECTIVE: To evaluate the dental arch relationship (DAR) of nonsyndromic unilateral cleft lip and palate (UCLP) and to explore the various phenotype and postnatal treatment factors that are responsible for poor DAR.

    DESIGN: Retrospective study.

    SETTING: School of Dental Science, Universiti Sains Malaysia.

    SUBJECTS: Eighty-four Bangladeshi children with nonsyndromic UCLP who received cheiloplasty and palatoplasty.

    MAIN OUTCOME MEASURES: Dental models were taken at 5 to 12 years of age (man: 7.69), and dental arch relationships were assessed using modified Huddart/Bodenham index (mHB) by two raters. Kappa statistics was used to evaluate the intra- and interexaminer agreements, chi-square was used to assess the associations, and logistic regression analysis was used to explore the responsible factors that affect DAR.

    RESULTS: The total mHB score (mean [SD]) was -8.261 (7.115). Intra- and interagreement was very good. Using crude and stepwise backward regression analysis, significant association was found between positive history of class III (P = .025, P = .030, respectively) and unfavorable DAR. Complete UCLP (P = .003) was also significantly correlated with unfavorable DAR.

    CONCLUSION: This multivariate study suggested complete type of UCLP and positive history of class III had a significantly unfavorable effect on the DAR.

    Matched MeSH terms: Malocclusion/classification*
  6. Fareen N, Alam MK, Khamis MF, Mokhtar N
    Orthod Craniofac Res, 2017 Aug;20(3):134-139.
    PMID: 28440029 DOI: 10.1111/ocr.12179
    OBJECTIVE: Reverse Twin-Block (RTB) and Reverse Pull Face Mask (RPFM) appliances are used to correct Class III malocclusion in growing patients. Aim of this retrospective study was to compare and analyse craniofacial changes produced by RTB and RPFM in the early and late mixed dentition in Malay children with Class III malocclusion.

    METHODS: Data consisted of pre- and post-treatment lateral cephalograms of 95 children, 49 patients with RTB and 46 patients with RPFM, divided into an early (8-9 year) and late (10-11 year) group. Treatment changes were assessed by the Ricketts analysis using CASSOS software, where 71 anatomic landmarks were identified in each cephalogram. Paired and independent t tests were performed for statistical comparison.

    RESULTS: Paired t test revealed significant changes in facial axis, facial angle, MD plane to FH, lower facial height, mandibular arc, maxillary convexity, U1 to APog, L1 to APog, L1 to APog angle and upper lip to E-plane measurements in RPFM, whereas significant changes were found in facial taper, U1 to APog and lower lip to E-plane values with RTB in the early treatment group. Independent t test revealed significant changes in U1 to APog, L1 to APog and U6 to PtV values in the RTB group. Post-treatment comparison of RTB and RPFM showed significant differences in L1 to APog and L1 to APog angle values.

    CONCLUSIONS: RPFM revealed more favourable craniofacial changes than RTB, particularly in the late mixed dentition stage.

    Matched MeSH terms: Malocclusion, Angle Class III/therapy*
  7. Wan Hassan WN, Yusof ZY, Makhbul MZ, Shahidan SS, Mohd Ali SF, Burhanudin R, et al.
    Health Qual Life Outcomes, 2017 Mar 21;15(1):54.
    PMID: 28327153 DOI: 10.1186/s12955-017-0632-x
    BACKGROUND: The Malay version of the Psychosocial Impact of Dental Aesthetics Questionnaire has been validated for use by Malaysian adolescents. Although Malay is their national language, English is widely used as the lingua franca among Malaysians of different ethnicities. This study aimed to validate an English version of the PIDAQ adapted for use by Malaysian adolescents to optimize data capture from adolescents who prefer English as the medium for communication.

    METHODS: The published English version of PIDAQ was pilot tested on 12- to 17-year-old adolescents, resulting in a few modifications to suit the Malaysian variety of English. Psychometric properties were tested on 393 adolescents who attended orthodontic practices and selected schools. Malocclusion was assessed using the Malocclusion Index, an aggregation of Perception of Occlusion Scale and the Aesthetic Component of the Index of Orthodontic Treatment Need, by the subjects (MI-S) and investigators (MI-D). Data were analysed for internal consistency and age-associated invariance, discriminant, construct and criterion validities, reproducibility and floor and ceiling effects using AMOS v.20 and SPSS v.20.

    RESULTS: The item Don't like own teeth on video of the Aesthetic Concern (AC) subscale was not relevant to a large proportion of participants (11.7%). Therefore, it was removed and the Malaysian English PIDAQ was analysed based on 22 items instead of 23 items. Confirmatory factor analysis showed good fit statistics (comparative fit index: 0.902, root-mean-square error of approximation: 0.066). Internal consistency was good for the Dental Self-Confidence, Social Impact and Psychological Impact subscales (Cronbach's alpha: 0.70-0.95) but lower (0.52-0.62) though acceptable for the AC subscale as it consisted of only 2 items. The reproducibility test was acceptable (intra-class correlations: 0.53-0.78). For all PIDAQ subscales, the MI-S and MI-D scores of those with severe malocclusion differed significantly from those with no or slight malocclusion. There were significant associations between the PIDAQ subscales with ranking of perceived dental appearance, need for braces and impact of malocclusion on daily activities. There were no floor or ceiling effects.

    CONCLUSION: The adapted Malaysian English PIDAQ demonstrated adequate psychometric properties that are valid and reliable for assessment of psychological impacts of dental aesthetics among Malaysian adolescents.

    Matched MeSH terms: Malocclusion/psychology*
  8. Ashari A, Mohamed AM
    Angle Orthod, 2016 Mar;86(2):337-42.
    PMID: 26017471 DOI: 10.2319/121014-896.1
    OBJECTIVE: To assess the impact of malocclusion on the quality of life.

    MATERIALS AND METHODS: This cross-sectional study involved 150 subjects attending the Primary Care Unit with no history of orthodontic treatment. The Dental Aesthetic Index (DAI) with 10 occlusal characteristics were measured on study models. Oral health-related quality of life (OHRQoL) was assessed with the Malaysian version of the Oral Health Impact Profile questionnaire (OHIP-14). The Spearman rank-order correlation coefficient was used to evaluate the relationship between the malocclusion and quality of life.

    RESULTS: Significantly weak correlations (r = .176) were found between the DAI and the OHRQoL. Females and the younger age group (12-19 years) tended to score higher on the OHIP-14 than their counterparts. For males, domain 3 (psychological discomfort; r = .462), domain 4 (physical disability; r = .312), domain 7 (handicap; r = .309), and overall score (r = .289) were weak correlates but significant to the DAI compared with females. The older age group showed a significant weak correlation in domain 3 (psychological discomfort; r = .268) and domain 7 (handicap; r = .238), whereas the younger age group showed no correlation with any domain.

    CONCLUSIONS: The DAI score does not predict the effect of malocclusion on the OHRQoL.

    Matched MeSH terms: Malocclusion/psychology*
  9. Gopinath VK, Ling KT, Haziani KN, Ismail NM
    J Clin Pediatr Dent, 2008;33(1):39-42.
    PMID: 19093650
    This study reports on the predisposing factors and prevalence of fractured anterior teeth among 12 and 16 years-old school children in Kubang Kerian, Kelantan, West Malaysia.
    Matched MeSH terms: Malocclusion/epidemiology
  10. Majid ZA
    Singapore Dent J, 1988 Dec;13(1):33-5.
    PMID: 2979012
    A sporadic case of Crouzon Syndrome without mental retardation is described. The patient, an 11 year old boy with grossly carious teeth and in severe pain was referred for dental treatment. A review of literature on Crouzon Syndrome is presented.
    Matched MeSH terms: Malocclusion
  11. Shahrin AA, Ghani SHA, Norman NH
    Korean J Orthod, 2021 Mar 25;51(2):86-94.
    PMID: 33678624 DOI: 10.4041/kjod.2021.51.2.86
    Objective: This study aimed to investigate the effect of micro-osteoperforations (MOPs) on external apical root resorption (EARR) during the initial orthodontic alignment phase of maxillary anterior crowding.

    Methods: Thirty patients (25 females, 5 males; mean age, 22.66 ± 3.27 years) who presented with moderate crowding of the upper labial segment and underwent extraction-based fixed appliance treatment were recruited. They were randomly allocated to receive adjunctive therapy with MOPs (n = 15) or treatment with fixed appliances only (control group; n = 15). EARR was measured from long-cone periapical radiographs taken at the start and the sixth month of treatment. A correction factor for the enlargement difference was used to calculate EARR. Data were analyzed with descriptive statistics and repeated-measures analysis of variance.

    Results: The mean root lengths of 168 teeth were measured and showed no statistically significant difference (p > 0.05) after six months of fixed appliance treatment in the MOP (mean difference [MD] = 0.13 mm; 95% confidence interval [CI] = -0.10-0.35) and control group (MD = 0.14 mm; 95% CI = -0.10-0.37). Most of the roots in the MOP and control groups (42.86% and 52.38%, respectively) showed only mild resorption. Less than 8% of the roots in both groups (7.14% in the MOP group and 4.76% in the control group) showed moderate resorption.

    Conclusions: Acceleration of orthodontic tooth movement with adjunctive MOPs therapy during the alignment phase does not exacerbate EARR in patients with moderate crowding of the upper labial segment in comparison with controls.

    Matched MeSH terms: Malocclusion
  12. Wan Hassan WN, Makhbul MZM, Yusof ZYM
    J Orofac Orthop, 2021 May 03.
    PMID: 33938957 DOI: 10.1007/s00056-021-00298-y
    PURPOSE: The sociodental model integrates clinical assessment, perceived impacts of malocclusion on quality of life, and behavioural propensity when prioritising orthodontic treatment. This study compares the effect of using different instruments to measure impact-related need on the assessment of orthodontic treatment need based on the sociodental framework.

    MATERIALS AND METHODS: In this cross-sectional study, 206 Malaysian adolescents (age: 11-18 years) were screened in orthodontic clinics to identify those with normative need, oral impacts due to malocclusion, and having high and medium-to-high behavioural propensities. The Index of Orthodontic Treatment Need classified normative need. The Psychosocial Impact of Dental Aesthetics (PIDA) questionnaire and the Condition-Specific Child-Oral Impacts on Daily Performances (CS-OIDP) index measured oral impacts. Subjects' behavioural propensities for successful treatment outcome were based on the Basic Periodontal Examination and International Caries Detection and Assessment System. Data were analysed using the McNemar test.

    RESULTS: The response rate was 99.0%. Estimates of normative need (89.7%) were significantly reduced under the sociodental model by 65.7% (p 

    Matched MeSH terms: Malocclusion
  13. Sockalingam SNMP, Zakaria ASI, Khan KAM, Azmi FM, Noor NM
    Case Rep Dent, 2020;2020:6972196.
    PMID: 32695527 DOI: 10.1155/2020/6972196
    The correction of rotated malpositioned tooth/teeth into the dental arch alignment in the mixed-dentition is often a challenging task for paediatric dentists. Failure in addressing this issue can bring about detrimental effect to the developing dentition and increases the probability of a complex orthodontic treatment in later years. Factors such as severity of the malpositioned teeth, patient's treatment compliance, limitation in specific functions of the selected appliance, availability of bone and space may dictate the success of the treatment. The combined use of a simple sectional orthodontic wire appliance and a 2 × 4 orthodontic appliance has been shown to produce a positive effect. The appliances resulted in derotation of the rotated malpositioned teeth and bringing them into arch alignment in two cases. This treatment option had eliminated the detrimental effects to the developing dentition and helped patients to enhance their smile and dental aesthetics.
    Matched MeSH terms: Malocclusion
  14. Alsanabani AAM, Yusof ZYM, Wan Hassan WN, Aldhorae K, Alyamani HA
    Children (Basel), 2021 May 25;8(6).
    PMID: 34070552 DOI: 10.3390/children8060448
    (1) Objectives: This paper aimed to cross-culturally adapt the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) into an Arabic language version (PIDAQ(A)) for measuring the oral health related quality of life related to dental aesthetics among 12-17-year-old Yemeni adolescents. (2) Material and methods: The study comprised three parts, which were linguistic validation and qualitative interview, comprehensibility assessment, and psychometric validations. Psychometric properties were examined for validity (exploratory factor analysis (EFA), partial confirmatory factor analysis (PCFA), construct, criterion, and discriminant validity) and reliability (internal consistency and reproducibility). (3) Results: The PIDAQ(A) contained a new item. EFA extracted three factors (item factor loading 0.375 to 0.918) comprising dental self-confidence, aesthetic concern, and psychosocial impact subscales. PCFA showed good fit statistics (comparative fit index (CFI) = 0.928, root-mean-square error of approximation (RMSEA) = 0.071). In addition, invariance across age groups was tested. Cronbach's α values ranged from 0.90 to 0.93 (intraclass correlations = 0.89-0.96). A criterion validity test showed that the PIDAQ(A) had a significant association with oral impacts on daily performance scores. A construct validity test showed significant associations between PIDAQ(A) subscales and self-perceived dental appearance and self-perceived need for orthodontic braces (p < 0.05). Discriminant validity presented significant differences in the mean PIDAQ(A) scores between subjects having severe malocclusion and those with slight malocclusion. No floor or ceiling effects were detected.
    Matched MeSH terms: Malocclusion
  15. Ruqoyyah Muslimat Othman, Noor Airin Aidil Koay, Sarah Haniza Abdul Ghani, Noraina Hafizan Norman
    MyJurnal
    Objective: To determine the prevalence of bimaxillary protrusion in general and the prevalence of skeletal Class I and dental Class I bimaxillary protrusion/ proclination among orthodontic patients attending postgraduate orthodontic clinic at Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Sungai Buloh, Malaysia. Materials and Methods: This is a cross sectional study which was carried out in two stages. The first part involves a random selection of 100 extra-oral profile photographs taken from postgraduate orthodontic residents’ patient list. The photographs were taken using Canon digital SLR camera EOS 70D with macro lens EF 100mm (Canon Inc., Tokyo, Japan) with patients in natural head position. The photographs were visually analysed for its bimaxillary protrusion features by two operators. The second part comprises of analyses of extra-oral profile photographs as well as intra-oral photographs of right buccal segment view which was conducted in two separate sittings. In the first sitting, five assessors analysed 259 extra - and intra-oral photographs followed by 40 photographs assessed in the second sitting for skeletal and dental Class I bimaxillary protrusion/ proclination. Statistical analysis for Kappa score was performed to assess the agreement between assessors using SPSS version 23 and Stata version 13. Results: The first part of the study showed an average prevalence of 34% with bimaxillary protrusion in 100 orthodontic patients. Whilst in the second part, prevalence of skeletal and dental Class I bimax ranging from 28 -33 per cent and 38-40 per cent respectively with very good and good inter-reliability agreement for both component. Conclusion: The prevalence of bimaxillary protrusion in general among UiTM orthodontic patients was found to range from 31 per cent to 37 per cent. Whilst the prevalence of skeletal and dental Class I bimax ranging from 28-33 per cent and 38-40 per cent respectively.
    Matched MeSH terms: Malocclusion
  16. Esa, R., Razak, I.A.
    Ann Dent, 1996;3(1):-.
    MyJurnal
    In Malaysia the School Dental Service (SDS) provides comprehensive dental treatment with the aim of rendering the child dentally fit before leaving primary school at 12 years. Hence the purpose of this study was to investigate I) the prevalence and treatment needs of traumatised permanent incisors and 2) to assess their relationship to the degree of incisor overjet amongst 12-13 year-old schoolchildren. The sample comprised of 1519 schoolchildren attending 20 secondary government and government-aided schools in Klang district. There were 772 boys and 747 girls. The sampling procedure involved a multistage, clustered and stratified random sampling. The prevalence of traumatic injuries in permanent incisors was 2.6% which confirmed the results of a previous local study. Boys suffered more trauma than girls with a ratio of about 1.5:I. A majority (77.5% ) of the children had one tooth affected. The most commonly affected teeth were the upper central incisors (91.8%) followed by the lower central incisors (4.1%). A high percentage (57.5%) of children with traumatised anterior teeth had increased overjet (>3mm). Almost all cases (93.9%) required two or more surface fillings. However the majority of affected children (56%) were satisfied with their appearance. It is concluded that traumatic dental injuries should be incorporated as part of the treatment plan for the SDS and appropriately managed soon after occurrence or not later than 12 years after which they leave the SDS. Future epidemiological studies should also give due emphasis to the relative importance of traumatised teeth in children.
    Matched MeSH terms: Malocclusion
  17. Mathew, Thomas
    Malaysian Dental Journal, 2010;31(2):84-89.
    MyJurnal
    The cleft lip and palate patients often have constricted maxillary arch, congenitally missing teeth, impacted teeth, and many kinds of malocclusion problems. Secondary bone grafting in cleft lip and palate patients is performed preferably before the eruption of permanent canine in order to provide adequate periodontal support for eruption and preservation of the teeth adjacent to the cleft. Secondary grafting with iliac marrow consistently produces trabecular bone to unify the maxilla and provide odontogenic support. Presented here is a case of unilateral cleft lip and palate, which was treated by expansion by quad helix and straight wire appliance for correction of dental malocclusion. Also discussed in detail the entire range of treatment procedures the boy underwent from 14 years of age, especially the role of secondary bone grafting with iliac marrow to facilitate the eruption of permanent impacted canine.
    Matched MeSH terms: Malocclusion
  18. Ang, Grace, Jacqueline Maryam Kamaluddin, Wizziyiane Ahmad, Uday Kumar Umesan, Siti Waznah Wahab, Naing, Lin
    MyJurnal
    his study assesses inter-examiner reproducibility in recording various malocclusion parameters and Index of Orthodontic Treatment Need (IOTN) grade during patient examination by utilising the kappa statistic. Five previously calibrated orthodontists clinically examined 233 non-orthodontically treated schoolchildren aged 14-17 years for recording various malocclusion parameters. The examination was repeated twice, thirty days apart and precluded the use of study-models or radiographs. Although good inter-examiner reproducibility was observed in recording incisor class, IOTN dental health grade, type of posterior crossbite, and excellent for parameters with absolute criteria like
    erupted supernumeraries, etc, substantial examiner variation resulted in only fair reproducibility for recording IOTN esthetic category, canine class, overbite category, traumatic overbite and upper centre-line shift of two millimetres or more from the facial midline. Reproducibility for detecting occlusal displacement in the presence of crossbite was poor, and kappa statistic was incalculable for recording openbite and number of upper incisors rotated 30° or more. Kappa was also incalculable for recording IOTN dental health subcategory due to the creation of asymmetric tables caused by rarely chosen subcategory options. Despite prior agreement between previously calibrated examiners on evaluation criteria, detection of certain malocclusion parameters during an epidemiological examination can prove to be challenging. Epidemiological studies that report on prevalence of malocclusion in the population should always report on the kappa reproducibility, especially if the study is carried out by multiple examiners.
    Matched MeSH terms: Malocclusion
  19. Wong, Lai Hong, Balkis Bashuri, Atiah Ayunni Abdul Ghani, Khairul Osman, Nor Atika Md Ashar
    MyJurnal
    Identifi cation of unknown suspect through bite marks has always been challenging. Narrowing list of suspects through sex and race markers is always recommend but rarely utilized due to limited publication in this area. Thus, this preliminary research was aimed to study the difference of bite mark made on dental wax between sex and race. A sample size of 40 UKM undergraduates comprising of Malay (male = 10, female = 10) and Chinese (male = 10, female = 10) were used in this study. Bite mark of subject was obtained through dental wax, digitally scanned and analyzed using Image-J software. Parameters measured were anterior teeth size, intercanine width and anterior teeth relative rotation. Result indicated that mandible left canine tooth size had signifi cant sexual dimorphism (p < 0.05) in differentiating sex. The means for male and female measured were 4.63 ± 1.05 mm and 5.35 ± 0.87 mm respectively. In addition to the result, tooth size of maxillary left canine and mandible left lateral incisor were signifi cantly different (p < 0.05) between races. Means for mandible left canine Malay and Chinese were 5.27 ± 1.01 mm and 4.50 ± 1.22 mm respectively. Furthermore, left lateral incisor mandible had means of 5.15 ± 0.87 mm and 4.60 ± 0.74 mm for Malay and Chinese respectively. Unfortunately, there were no signifi cant differences for intercanine width and anterior teeth relative rotation between the two major races in Malaysia. In conclusion, this research has demonstrated the possibility of using tooth size of mandible left canine, maxillary left canine and mandible left lateral discriminate sex and race.
    Matched MeSH terms: Malocclusion
  20. Khairani Idah Mokhtar, Noraini Abu Bakar, Azrul Fazwan Kharuddin
    MyJurnal
    Runt-related transcription factor 2 (RUNX2) plays important roles in osteoblast
    differentiation, tooth development and chondrocyte maturation; hence its involvement in
    craniofacial development is paramount. Mutation in RUNX2 is implicated with cleidocranial
    dysplasia; a bone development disorder, while single nucleotide polymorphism (SNP) in RUNX2 is
    associated with Class II/2 malocclusion. This study aimed to determine RUNX2 SNP of DNA marker
    (rs6930053) in malocclusion patients from local population. (Copied from article).
    Matched MeSH terms: Malocclusion
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