Displaying publications 81 - 100 of 145 in total

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  1. Pardo LE, Campbell MJ, Edwards W, Clements GR, Laurance WF
    PLoS One, 2018;13(5):e0197539.
    PMID: 29795615 DOI: 10.1371/journal.pone.0197539
    The rapid expansion of oil palm cultivation in the Neotropics has generated great debate around possible biodiversity impacts. Colombia, for example, is the largest producer of oil palm in the Americas, but the effects of oil palm cultivation on native fauna are poorly understood. Here, we compared how richness, abundance and composition of terrestrial mammal species differ between oil palm plantations and riparian forest in the Colombian Llanos region. Further, we determined the relationships and influence of landscape and habitat level variables on those metrics. We found that species richness and composition differed significantly between riparian forest and oil palm, with site level richness inside oil palm plantations 47% lower, on average, than in riparian forest. Within plantations, mammalian species richness was strongly negatively correlated with cattle abundance, and positively correlated with the density of undergrowth vegetation. Forest structure characteristics appeared to have weak and similar effects on determining mammal species richness and composition along riparian forest strips. Composition at the landscape level was significantly influenced by cover type, percentage of remaining forest and the distance to the nearest town, whereas within oil palm sites, understory vegetation, cattle relative abundance, and canopy cover had significant effects on community composition. Species specific abundance responses varied between land cover types, with oil palm having positive effects on mesopredators, insectivores and grazers. Our findings suggest that increasing habitat complexity, avoiding cattle and retaining native riparian forest-regardless of its structure-inside oil palm-dominated landscapes would help support higher native mammal richness and abundance at both local and landscape scales.
    Matched MeSH terms: Mammals*
  2. Tsutsui K, Ubuka T, Son YL, Bentley GE, Kriegsfeld LJ
    PMID: 26635728 DOI: 10.3389/fendo.2015.00179
    Since the discovery of gonadotropin-releasing hormone (GnRH) in mammals at the beginning of the 1970s, it was generally accepted that GnRH is the only hypothalamic neuropeptide regulating gonadotropin release in mammals and other vertebrates. In 2000, however, gonadotropin-inhibitory hormone (GnIH), a novel hypothalamic neuropeptide that actively inhibits gonadotropin release, was discovered in quail. Numerous studies over the past decade and a half have demonstrated that GnIH serves as a key player regulating reproduction across vertebrates, acting on the brain and pituitary to modulate reproductive physiology and behavior. In the latter case, recent evidence indicates that GnIH can regulate reproductive behavior through changes in neurosteroid, such as neuroestrogen, biosynthesis in the brain. This review summarizes the discovery of GnIH, and the contributions to GnIH research focused on its mode of action, regulation of biosynthesis, and how these findings advance our understanding of reproductive neuroendocrinology.
    Matched MeSH terms: Mammals
  3. Colozza G, Lee H, Merenda A, Wu SS, Català-Bordes A, Radaszkiewicz TW, et al.
    Sci Adv, 2023 Nov 24;9(47):eadh9673.
    PMID: 38000028 DOI: 10.1126/sciadv.adh9673
    The mammalian intestine is one of the most rapidly self-renewing tissues, driven by stem cells residing at the crypt bottom. Paneth cells form a major element of the niche microenvironment providing various growth factors to orchestrate intestinal stem cell homeostasis, such as Wnt3. Different Wnt ligands can selectively activate β-catenin-dependent (canonical) or -independent (noncanonical) signaling. Here, we report that the Dishevelled-associated activator of morphogenesis 1 (Daam1) and its paralogue Daam2 asymmetrically regulate canonical and noncanonical Wnt (Wnt/PCP) signaling. Daam1/2 interacts with the Wnt inhibitor RNF43, and Daam1/2 double knockout stimulates canonical Wnt signaling by preventing RNF43-dependent degradation of the Wnt receptor, Frizzled (Fzd). Single-cell RNA sequencing analysis revealed that Paneth cell differentiation is impaired by Daam1/2 depletion because of defective Wnt/PCP signaling. Together, we identified Daam1/2 as an unexpected hub molecule coordinating both canonical and noncanonical Wnt, which is fundamental for specifying an adequate number of Paneth cells.
    Matched MeSH terms: Mammals
  4. Nor Nasyitah Ismail, Khairani Idah Mokhtar
    MyJurnal
    Oral cancer is one of the common cancer cases identified in the developing countries. Genetic mutation and overexpression of certain genes and proteins have been associated in the development of this cancer. Notch signalling pathway is normally involved in controlling the development process of vertebrates and invertebrates; however, deregulation of this pathway was found to be responsible in the formation of certain cancers including oral cancers. Activation of this pathway requires binding of the ligands to its receptors. Four NOTCH receptors (NOTCH 1, 2, 3 and 4) have been identified in mammals. Disruptions within these molecules might interfere with the normal functions of Notch signalling pathway. Hence, this study was conducted to detect mutations of NOTCH1 and NOTCH2 receptor genes which might be occurring in the oral cancer cases obtained from the local population. DNA extracted from fresh-frozen tissue biopsy of the tongue and buccal mucosa from 10 confirmed cases of oral cancer were subjected for polymerase chain reaction (PCR) amplification using the specific sets of primers. The PCR products were sent for sequencing before final results were analysed.
    Due to time and cost limitation, only two out of four NOTCH receptor genes; NOTCH1 and NOTCH2, were used in this analysis. The results revealed absence of nucleotide changes for both NOTCH receptor genes amplified from these oral cancer samples. More samples and further analysis looking into other regions in these genes are required to conclude the involvement of NOTCH receptor genes mutation in causing oral cancer.
    Matched MeSH terms: Mammals
  5. Bhat R, Karim AA
    J Food Sci Technol, 2014 Jul;51(7):1326-33.
    PMID: 24966426 DOI: 10.1007/s13197-012-0652-9
    Developing novel fish gelatin films with better mechanical properties than mammalian gelatin is a challenging but promising endeavor. Studies were undertaken to produce fish gelatin films by combining treatments with different sugars (ribose and lactose) followed 'by' 'and' ultraviolet (UV) radiation, as possible cross-linking agents. Increase in tensile strength and percent elongation at break was recorded, which was more significant in films without sugars that were exposed to UV radiation. Films with added ribose showed decreased solubility after UV treatment and exhibited higher swelling percentage than films with added lactose, which readily dissolved in water. FTIR spectra of all the films showed identical patterns, which indicated no major changes to have occurred in the functional groups as a result of interaction between gelatin, sugars and UV irradiation. The results of this study could be explored for commercial use, depending on industrial needs for either production of edible films or for food packaging purposes.
    Matched MeSH terms: Mammals
  6. Gunasekara YD, Kottawatta SA, Nisansala T, Wijewickrama IJB, Basnayake YI, Silva-Fletcher A, et al.
    Zoonoses Public Health, 2024 Feb;71(1):84-97.
    PMID: 37880923 DOI: 10.1111/zph.13087
    This study aimed to investigate and compare the proportion of AMR Escherichia coli (E. coli) between urban (Dompe in the Western province) and rural (Dambana in the Sabaragamuwa province) areas in Sri Lanka. The overall hypothesis of the study is that there is a difference in the proportion of AMR E. coli between the urban and the rural areas. Faecal samples were collected from healthy humans (n = 109), dairy animals (n = 103), poultry (n = 35), wild mammals (n = 81), wild birds (n = 76), soil (n = 80) and water (n = 80) from both areas. A total of 908 E. coli isolates were tested for susceptibility to 12 antimicrobials. Overall, E. coli isolated from urban area was significantly more likely to be resistant than those isolated from rural area. The human domain of the area had a significantly higher prevalence of AMR E. coli, but it was not significantly different in urban (98%) and rural (97%) areas. AMR E. coli isolated from dairy animals, wild animals and water was significantly higher in the urban area compared with the rural area. There was no significant difference in the proportion of multidrug resistance (MDR) E. coli isolated from humans, wild animals and water between the two study sites. Resistant isolates found from water and wild animals suggest contamination of the environment. A multi-sectorial One Health approach is urgently needed to control the spread of AMR and prevent the occurrences of AMR in Sri Lanka.
    Matched MeSH terms: Mammals
  7. Yeo XY, Chae WR, Lee HU, Bae HG, Pettersson S, Grandjean J, et al.
    Gut Microbes, 2023 Dec;15(2):2283911.
    PMID: 38010368 DOI: 10.1080/19490976.2023.2283911
    The complex symbiotic relationship between the mammalian body and gut microbiome plays a critical role in the health outcomes of offspring later in life. The gut microbiome modulates virtually all physiological functions through direct or indirect interactions to maintain physiological homeostasis. Previous studies indicate a link between maternal/early-life gut microbiome, brain development, and behavioral outcomes relating to social cognition. Here we present direct evidence of the role of the gut microbiome in brain development. Through magnetic resonance imaging (MRI), we investigated the impact of the gut microbiome on brain organization and structure using germ-free (GF) mice and conventionalized mice, with the gut microbiome reintroduced after weaning. We found broad changes in brain volume in GF mice that persist despite the reintroduction of gut microbes at weaning. These data suggest a direct link between the maternal gut or early-postnatal microbe and their impact on brain developmental programming.
    Matched MeSH terms: Mammals
  8. Jamal, P., Jaswir, I., Yusof, N., Jami, M.S.
    MyJurnal
    Gelatin from fish skin is known to be an alternative source for mammalian gelatin. However, it has weaker properties compared to bovine and porcine gelatin, which limits its use in the industry. The conventional method for fish gelatin extraction requires long production time and could cause serious water pollution and chemical treatments are often being used to enhance the yield of fish gelatin and its properties but it may affect the amino acid content of the gelatin. In this regard, High-Pressure Processing (HPP) is a novel method suggested for fish gelatin extraction. The HPP method is classified as green technology as it requires low electricity throughout the process. This study will discuss the impact of HPP the technique gelatin extracted from fish skin. Skins from four types of fish, namely red tilapia (Oreochromis niloticus), black tilapia (Oreochromis mossambicus), grouper (Epinephelus areolatus) and threadfin bream (Nemipterus tambuloides), were used. High pressure was applied at either pretreatment in citric acid solution or during thermal extraction; and the pressure was maintained at 250 MPa with pressure holding time of 10 minutes and 18 hours of water extraction. Gelatin extract from traditional acid-base method was prepared as a standard for comparison. The study found that there was an increment in the yield of gelatin and the concentration of gelatin extract, and the pre-treatment time was also reduced.
    Matched MeSH terms: Mammals
  9. Ding K, Geng H, Guo W, Sun W, Zhan S, Lou Q, et al.
    J Sci Food Agric, 2023 Aug 30;103(11):5322-5331.
    PMID: 37016806 DOI: 10.1002/jsfa.12600
    BACKGROUND: Fish gelatin (FG) has multifunctional properties similar to mammalian gelatin (MG), and it has been recognized as the optimal alternative to MG. While its poor surface-active and gelling properties significantly limit its application values, glycosylation has been successfully used to increase surface-active properties of FG, but the influence of ultrasonic-associated glycosylation (UAG) on the gelling and structural characteristics of FG is still rarely reported. This article explores UAG (100-200 W, 0.5-1 h) with κ-carrageenan (κC) on the functional properties (emulsifying, gelling and rheological properties) and structural characteristics of FG.

    RESULTS: The longer time and higher power of ultrasonics accelerated the glycosylation reaction with an increase in glycosylation degree and browning index values. Compared with original FG, FG-κC mixture and bovine gelatin, UAG-modified FG possessed higher emulsification activity index, emulsion stability index, gel strength, hardness and melting temperature values. Among them, gelatin modified by appropriate ultrasonic conditions (200 W, 0.5 h) had the highest emulsifying and gelling properties. Rheological results showed that UAG contributed to the gelation process of gelatin with advanced gelation time and endowed it with high viscosity. Structural analysis indicated that UAG promoted κC to link with FG by the formation of covalent and hydrogen bonds, restricting more bound and immobilized water in the gels, exhibiting higher gelling properties.

    CONCLUSION: This work showed that UAG with κC is a promising method to produce high gelling and emulsifying properties of FG that could replace MG. © 2023 Society of Chemical Industry.

    Matched MeSH terms: Mammals
  10. Mastor NN, Subbiah VK, Bakar WNWA, Begum K, Alam MJ, Hoque MZ
    Data Brief, 2020 Dec;33:106370.
    PMID: 33102652 DOI: 10.1016/j.dib.2020.106370
    Enterococcus gallinarum is a gram positive facultatively anaerobic bacteria that is typically found in mammalian intestinal tracts. It is generally not considered pathogenic to humans and is rarely reported. Here, we present the draft genome sequence data of Enterococcus gallinarum strain EGR748 isolated from a human clinical sample, and sequenced using the Illumina HiSeq 4000 system. The estimated whole genome size of the strain was 3,730,000 bp with a G + C content of 40.43%. The de novo assembly of the genome generated 55 contigs with an N50 of 208,509 bp. In addition, the Maximum Likelihood phylogenetic analysis based on the 16S rRNA sequence data accurately clustered EGR748 with other E. gallinarum strains. The data may be useful to demonstrate the capacity of this enterococcal species becoming the causal agents of nosocomial blood-stream infections. The genome dataset has been deposited at DDBJ/ENA/GenBank under the accession number JAABOR000000000.
    Matched MeSH terms: Mammals
  11. Kan HW, Peng WH, Wu CC, Wang DW, Lee MT, Lee YK, et al.
    Psychopharmacology (Berl), 2022 Dec;239(12):3805-3818.
    PMID: 36221037 DOI: 10.1007/s00213-022-06250-1
    RATIONALE: Clinical reports reveal that scopolamine, an acetylcholine muscarinic receptor antagonist, exerts rapid antidepressant effects in depressed patients, but the mechanisms underlying the therapeutic effects have not been fully identified.

    OBJECTIVES: The present study examines the cellular mechanisms by which scopolamine produces antidepressant-like effects through its action in the ventrolateral midbrain periaqueductal gray (vlPAG).

    METHODS: We used a well-established mouse model of depression induced by chronic restraint stress (CRS) exposure for 14 days. Behaviors were tested using the forced swim test (FST), tail suspension test (TST), female urine sniffing test (FUST), novelty-suppressed feeding test (NSFT), and locomotor activity (LMA). Synaptic transmission in the vlPAG was measured by whole-cell patch-clamp recordings. IntravlPAG microinjection was used to pharmacologically verify the signaling cascades of scopolamine in the vlPAG.

    RESULTS: The results demonstrated that intraperitoneal injection of scopolamine produced antidepressant-like effects in a dose-dependent manner without affecting locomotor activity. CRS elicited depression-like behaviors, whereas intraperitoneal injection of scopolamine alleviated CRS-induced depression-like behaviors. CRS diminished glutamatergic transmission in the vlPAG, while scopolamine reversed the above effects. Moreover, intravlPAG microinjection of the L-type voltage-dependent calcium channel (VDCC) blocker verapamil, tropomyosin-related kinase B (TrkB) receptor antagonist ANA-12, mammalian target of rapamycin complex 1 (mTORC1) inhibitor rapamycin, and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA) antagonist CNQX prevented scopolamine-induced antidepressant-like effects.

    CONCLUSIONS: Scopolamine ameliorated CRS-elicited depression-like behavior required activation of VDCC, resulting in activity-dependent release of brain-derived neurotrophic factor (BDNF), engaging the TrkB receptor and downstream mTORC1 signaling in the vlPAG.

    Matched MeSH terms: Mammals/metabolism
  12. Mariana A, Mohd KB, Halimaton I, Suhaili ZA, Shahrul-Anuar MS, Nor ZM, et al.
    Asian Pac J Trop Biomed, 2011 Jan;1(1):1-5.
    PMID: 23569714 DOI: 10.1016/S2221-1691(11)60057-9
    To identify the presence of acarine ectoparasites and determine whether there is any potential public health risk in Panti Forest Reserve, Johore, Malaysia.
    Matched MeSH terms: Mammals/parasitology*
  13. Lim Boo Liat, Heyneman D
    Med J Malaya, 1965 Sep;20(1):54.
    PMID: 4221415
    Matched MeSH terms: Mammals*
  14. Azmiera N, Mariana A, Pimsler ML, Heo CC
    J Med Entomol, 2020 09 07;57(5):1354-1363.
    PMID: 32440683 DOI: 10.1093/jme/tjaa086
    Mite biodiversity and distribution in Malaysia is currently understudied. Most previous works on Malaysian Acari have focused on pest organisms of medical, veterinary, and agricultural concern, with a few recent studies centered on mites in forensic contexts. Previous literatures have targeted collection sites in forest reserves and/or mountains in either Peninsular or Malaysian Borneo, though the state of Sarawak had the least publications related to mite species descriptions despite having the highest number of nature parks of any state in the country. Most publications focused on the three states Selangor, Pahang and Sabah. Most of the mite species reported were from mammals (66.3%), with fewer species from birds (21.7%), arthropods (11.2%), and reptiles (0.8%). We believe that further work on the systematic documentation of mite species throughout Malaysia is necessary as it could generate useful tools, such as the use of mites as biogeographical markers or as forensic indicators. Therefore, this review catalogs mite species that have been documented in or on animal hosts in Malaysia and serves as a foundation for future work.
    Matched MeSH terms: Mammals/parasitology*
  15. Kazim AR, Houssaini J, Tappe D, Heo CC
    Zootaxa, 2023 Apr 04;5263(1):40-60.
    PMID: 37045000 DOI: 10.11646/zootaxa.5263.1.2
    Literature records of chewing lice (Phthiraptera) from mammals in Malaysia were checked and reviewed, resulting in a list of 13 confirmed species belonging to eight genera (Bovicola, Felicola, Gliricola, Gyropus, Haematomyzus, Heterodoxus, Lorisicola, Trichodectes) from four families (Boopiidae, Gyropidae, Haematomyzidae, Trichodectidae) in three suborders (Amblycera, Ischnocera, Rhynchophthirina). We present a checklist of those 13 chewing lice recorded from Peninsular Malaysia and Malaysian Borneo, including hosts, localities, and literature references. An additional 12 species are listed and discussed as possibly occurring in this country. A host-louse list is also given.
    Matched MeSH terms: Mammals
  16. Kazim AR, Houssaini J, Tappe D, Heo CC
    Zootaxa, 2022 Dec 02;5214(3):301-336.
    PMID: 37044900 DOI: 10.11646/zootaxa.5214.3.1
    Literature records of sucking lice (Phthiraptera: Anoplura) from Malaysia were checked and reviewed, resulting in a list of 34 established species belonging to 11 genera (Ancistroplax, Atopophthirus, Enderleinellus, Haematopinus, Hamophthirius, Hoplopleura, Linognathus, Neohaematopinus, Pedicinus, Polyplax and Sathrax). Furthermore, three local and six cosmopolitan louse species are regarded as dubious in Malaysia, due to misidentifications or lack of locality records. Also, pathogens known to be associated with the sucking lice are listed. The alarming conservation status of some Malaysian mammalian host species and their sucking lice warrant more research and imminent action to preserve the biodiversity of the country. This paper presents the first complete checklist of anopluran lice from both Peninsular Malaysia and Malaysian Borneo, including localities, literature references and a host-louse list.
    Matched MeSH terms: Mammals
  17. Brodie JF, Strimas-Mackey M, Mohd-Azlan J, Granados A, Bernard H, Giordano AJ, et al.
    Proc Biol Sci, 2017 01 25;284(1847).
    PMID: 28100818 DOI: 10.1098/rspb.2016.2335
    The responses of lowland tropical communities to climate change will critically influence global biodiversity but remain poorly understood. If species in these systems are unable to tolerate warming, the communities-currently the most diverse on Earth-may become depauperate ('biotic attrition'). In response to temperature changes, animals can adjust their distribution in space or their activity in time, but these two components of the niche are seldom considered together. We assessed the spatio-temporal niches of rainforest mammal species in Borneo across gradients in elevation and temperature. Most species are not predicted to experience changes in spatio-temporal niche availability, even under pessimistic warming scenarios. Responses to temperature are not predictable by phylogeny but do appear to be trait-based, being much more variable in smaller-bodied taxa. General circulation models and weather station data suggest unprecedentedly high midday temperatures later in the century; predicted responses to this warming among small-bodied species range from 9% losses to 6% gains in spatio-temporal niche availability, while larger species have close to 0% predicted change. Body mass may therefore be a key ecological trait influencing the identity of climate change winners and losers. Mammal species composition will probably change in some areas as temperatures rise, but full-scale biotic attrition this century appears unlikely.
    Matched MeSH terms: Mammals*
  18. Hasnah Haron, Nurul Hidayah Aminudin, Nik Shanita Safii, Hazila Khalid
    MyJurnal
    Kajian ini bertujuan untuk membandingkan kandungan makronutrien dalam tiga jenis kuih manis tempatan iaitu kuih seri muka (SM), kuih bakar (B) dan kuih wajik (W) yang mana resepinya telah dibentuk secara pengiraan nutrien yang berdasarkan Jadual Komposisi Makanan Malaysia (JKMMM) dengan kaedah analisis secara proksimat. Penentuan kandungan makronutrien secara spesifik ditentukan menggunakan kaedah analisis proksimat manakala penentuan tenaga dan karbohidrat total dijalankan melalui pengiraan. Hasil analisis proksimat menunjukkan W mengandungi karbohidrat total tertinggi (61.5 ± 1.6%) secara signifikan (p < 0.05), berbanding B (39.3 ± 1.5%) dan SM (38.7 ± 1.5%). SM mempunyai kandungan air yang lebih tinggi (46.7 ± 1.6%) secara signifikan (p < 0.05) berbanding B (42.5 ± 6.6 %) dan W (30.2 ± 0.4%). B mengandungi kandungan protein tertinggi (6.1 ± 0.9%) secara signifikan berbanding dengan W (3.0 ± 0.3%). Tiada perbezaan yang signifikan bagi kandungan lemak di antara B (12.8 ± 1.8%), SM (9.9 ± 0.2%) dan W (8.2 ± 2.6%). Jumlah kalori untuk W adalah tertinggi (332 kcal/100g) diikuti oleh B (299 kcal/100g) dan SM (262 kcal/100g). Secara umumnya, nilai kandungan makronutrien dari analisis proksimat adalah lebih rendah berbanding secara pengiraan kandungan makronutrien menggunakan JKMMM. Ini disebabkan pengiraan berdasarkan JKMMM adalah berdasarkan bahan mentah manakala analisis proksimat berdasarkan sampel kuih yang telah disediakan.


    Matched MeSH terms: Mammals
  19. Rayani M, Zasmy Unyah N, Hatam G
    Iran J Parasitol, 2014 Mar;9(1):70-8.
    PMID: 25642262
    Giardia duodenalis is one of the most common human intestinal protozoan parasites worldwide and is endemic throughout the world with a vast range of mammalian hosts. The present study aimed to identify the prevalence of G. duodenalis isolates and determine the most common of its assemblages in the patients referring to health centers and hospitals in Fars province, Iran that will be subjected to further molecular investigation.
    Matched MeSH terms: Mammals
  20. Kai Z, Woan TS, Jie L, Goodale E, Kitajima K, Bagchi R, et al.
    PLoS One, 2014;9(1):e86598.
    PMID: 24466163 DOI: 10.1371/journal.pone.0086598
    The value of local ecological knowledge (LEK) to conservation is increasingly recognised, but LEK is being rapidly lost as indigenous livelihoods change. Biodiversity loss is also a driver of the loss of LEK, but quantitative study is lacking. In our study landscape in SW China, a large proportion of species have been extirpated. Hence, we were interested to understand whether species extirpation might have led to an erosion of LEK and the implications this might have for conservation. So we investigated peoples' ability to name a selection of birds and mammals in their local language from pictures. Age was correlated to frequency of forest visits as a teenager and is likely to be closely correlated to other known drivers of the loss of LEK, such as declining forest dependence. We found men were better at identifying birds overall and that older people were better able to identify birds to the species as compared to group levels (approximately equivalent to genus). The effect of age was also stronger among women. However, after controlling for these factors, species abundance was by far the most important parameter in determining peoples' ability to name birds. People were unable to name any locally extirpated birds at the species level. However, contrary to expectations, people were better able to identify extirpated mammals at the species level than extant ones. However, extirpated mammals tend to be more charismatic species and several respondents indicated they were only familiar with them through TV documentaries. Younger people today cannot experience the sights and sounds of forest animals that their parents grew up with and, consequently, knowledge of these species is passing from cultural memory. We suggest that engaging older members of the community and linking the preservation of LEK to biodiversity conservation may help generate support for conservation.
    Matched MeSH terms: Mammals
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