Displaying publications 121 - 140 of 2446 in total

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  1. Chan LK, Lee KL, Tan SE
    Med J Malaya, 1967 Dec;22(2):94-8.
    PMID: 4231985
    Matched MeSH terms: Pregnancy*
  2. Ong HC
    Trop Geogr Med, 1974 Dec;26(4):384-8.
    PMID: 4456697
    Matched MeSH terms: Pregnancy*; Pregnancy Complications/epidemiology; Pregnancy Complications, Hematologic/epidemiology; Pregnancy Complications, Infectious/epidemiology
  3. Beck AJ, Lim BL
    Acta Trop, 1973;30(4):251-60.
    PMID: 4147874
    Matched MeSH terms: Pregnancy; Pregnancy, Animal
  4. Woon FC, Chin YS, Ismail IH, Batterham M, Abdul Latiff AH, Gan WY, et al.
    PLoS One, 2019;14(6):e0216439.
    PMID: 31233513 DOI: 10.1371/journal.pone.0216439
    BACKGROUND: Despite perennial sunshine, vitamin D deficiency is prevalent among Malaysians especially pregnant women. This study determines the vitamin D status and its associated factors among third trimester pregnant women attending government health clinics in Selangor and Kuala Lumpur, Malaysia.

    METHODS: Information on socio-demographic characteristics, obstetrical history, and sun exposure were obtained through face-to-face interviews. Vitamin D intake was assessed using a semi-quantitative food frequency questionnaire (FFQ). Serum 25-hydroxyvitamin D concentration was measured and classified as deficient (< 30 nmol/L), insufficient (30-50 nmol/L), and sufficient (≥ 50 nmol/L).

    RESULTS: Of the 535 pregnant women recruited, 42.6% were vitamin D deficient. They consumed an average of 8.7 ± 6.7 μg of vitamin D daily. A total of 80.4% of the vitamin D were obtained from the food sources, while 19.6% were from dietary supplements. Fish and fish products showed the highest contribution to vitamin D intake (35.8%). The multivariable generalized linear mixed models, with clinic as a random effect, indicates that higher intake of vitamin D is associated with lower odds of vitamin D deficiency among pregnant women (OR = 0.96; 95% CI = 0.93-0.99). The odds of having vitamin D deficiency was reduced by 87% in non-Malays (OR = 0.14; 95% CI = 0.05-0.41) compared to Malays. No associations were found between age, educational level, monthly household income, work status, gravidity, parity, pre-pregnancy body mass index, total hours of sun exposure, total percentage of body surface area, and sun exposure index per day with vitamin D deficiency.

    CONCLUSION: Vitamin D deficiency is prevalent among Malaysian pregnant women. Considering the possible adverse obstetric and fetal outcomes of vitamin D deficiency during pregnancy, future nutrition education should emphasise on vitamin D-fortified foods consumption among pregnant women by taking into consideration ethnic differences.
    Matched MeSH terms: Pregnancy*
  5. Soe MZ, Hayati F, Abdul Rahim SSS
    J Coll Physicians Surg Pak, 2022 Mar;32(3):409-410.
    PMID: 35148605 DOI: 10.29271/jcpsp.2022.03.409
    Null.
    Matched MeSH terms: Pregnancy; Pregnancy Trimester, First
  6. Salleha Khalid, Muhammad Shamsir Mohd Aris
    MyJurnal
    Teenage pregnancy is associated with maternal and neonatal morbidity. Some postulate that it is due to biological immaturity, while others postulate that it is due to inadequate antenatal care. The objective of this study is to compare the maternal and neonatal outcome between married and unmarried teenage mothers. A retrospective study was conducted from 2009 to 2012, where mothers aged below 20 year old were included. Maternal and neonatal outcome was assessed. A total of 750 patients aged below 20 year old delivered at Hospital Ampang. The trend of teenage pregnancy decreased from 3.1% in 2009 to 2.2% in 2012. A total of 578 (77.1%) mothers were married, while 172 (22.9%) were unmarried. Being unmarried was significantly associated with unbooked (p<0.001), preterm birth (p= 0.00468), and lower birth weight (p< 0.0001, and unpaired T-Test with 95% CI -0.2607 to -0.0933). However there is no significant difference in the number of mothers with hypertensive disease (p= 0.88428), diabetes in pregnancy (p= 0.39602), mode of delivery (p= 0.055 vaginal delivery, p = 0.4419 caesarean section, and p= 0.9097 instrumental deliveries) and NICU admission (p= 0.3779) between the two groups. Unmarried teenage pregnancy is associated with a lack of antenatal care, preterm birth, and lower birth weight compared to their married counterpart.
    Keywords: Marital status, pregnancy outcome, teenage pregnancy
    Matched MeSH terms: Pregnancy in Adolescence*
  7. Tan PC, Ramasandran G, Sethi N, Razali N, Hamdan M, Kamarudin M
    BMC Pregnancy Childbirth, 2023 Jun 17;23(1):450.
    PMID: 37330467 DOI: 10.1186/s12884-023-05771-7
    BACKGROUND: Hyperemesis gravidarum (HG) affects about 2% of pregnancies and is at the severe end of the spectrum of nausea and vomiting of pregnancy. HG causes severe maternal distress and results in adverse pregnancy outcomes long after the condition may have dissipated. Although dietary advice is a common tool in management, trial evidence to base the advice on is lacking.

    METHODS: A randomized trial was conducted in a university hospital from May 2019 to December 2020. 128 women at their discharge following hospitalization for HG were randomized: 64 to watermelon and 64 to control arm. Women were randomized to consume watermelon and to heed the advice leaflet or to heed the dietary advice leaflet alone. A personal weighing scale and a weighing protocol were provided to all participants to take home. Primary outcomes were bodyweight change at the end of week 1 and week 2 compared to hospital discharge.

    RESULTS: Weight change (kg) at end of week 1, median[interquartile range] -0.05[-0.775 to + 0.50] vs. -0.5[-1.4 to + 0.1] P = 0.014 and to the end of week 2, + 0.25[-0.65 to + 0.975] vs. -0.5[-1.3 to + 0.2] P = 0.001 for watermelon and control arms respectively. After two weeks, HG symptoms assessed by PUQE-24 (Pregnancy-Unique Quantification of Emesis and Nausea over 24 h), appetite assessed by SNAQ (Simplified Nutritional Appetite Questionnaire), wellbeing and satisfaction with allocated intervention NRS (0-10 numerical rating scale) scores, and recommendation of allocated intervention to a friend rate were all significantly better in the watermelon arm. However, rehospitalization for HG and antiemetic usage were not significantly different.

    CONCLUSION: Adding watermelon to the diet after hospital discharge for HG improves bodyweight, HG symptoms, appetite, wellbeing and satisfaction.

    TRIAL REGISTRATION: This study was registered with the center's Medical Ethics Committee (on 21/05/2019; reference number 2019327-7262) and the ISRCTN on 24/05/2019 with trial identification number: ISRCTN96125404 . First participant was recruited on 31/05/ 2019.

    Matched MeSH terms: Pregnancy; Pregnancy Outcome
  8. Ng PH, NorAzlin MI, Nasri NI
    Int J Gynaecol Obstet, 2007 Dec;99(3):251.
    PMID: 17888439
    Matched MeSH terms: Pregnancy; Pregnancy Complications/pathology*; Pregnancy, Ectopic/drug therapy*; Pregnancy, Ectopic/pathology
  9. Achanna S, Monga D
    Med J Malaysia, 1995 Mar;50(1):37-41.
    PMID: 7752974
    The obstetric performance of 59 elderly primigravidae delivering at the University Hospital, Kelantan, between January 1, 1987 and December 12, 1988 is compared with that of 60 young primigravidae delivering during the same time period. The total number of deliveries during this period was 16,284, and the predominant ethnic group was Malays. Apart from an increased incidence of preeclampsia (23.7% vs. 13.3%), breech presentation (6.78% vs. 3.33%) and Caesarean sections (74.6% vs. 10%) among the study group, there were no other statistically significant obstetric complications. Majority of Caesarean sections were done as emergency procedures, the principal indications being poor progress of labour and foetal distress. The neonatal outcome (in terms of birthweight, gestational age and breastfeeding at discharge) was similar in the two groups. For most women in both groups this was the first marriage, though a higher proportion in the study group had an interval of more than two years between marriage and childbirth.
    Matched MeSH terms: Pregnancy/physiology*; Pregnancy Complications/epidemiology; Pregnancy, High-Risk*
  10. Urquhart DR, Tai C
    Asia Oceania J Obstet Gynaecol, 1991 Dec;17(4):321-5.
    PMID: 1801677
    The obstetric performance of 240 elderly primigravida delivering at the University Hospital, Kuala Lumpur, Malaysia between January 1987 and February 1990 was compared with a random group of 250 young primigravida delivering during the same time period. The incidence of impaired glucose tolerance, diabetes mellitus, preterm delivery, antepartum haemorrhage and malpresentation was all increased in the elderly primigravida group. The incidence of caesarean section in the older group was 40.4% compared with 6.8% in the younger (p less than 0.001). Recent studies suggest that the perinatal mortality in women who delay having their first baby until after the age of 35 is not significantly different from the rest of the obstetric population. However, in our own population of elderly primigravida, although not quite reaching statistical significance the perinatal mortality rate of 46 per 1,000 is three times that of primigravida aged 20-25. This may reflect our low induction rate (7.5%) and assisted vaginal delivery rate (8.3%) in those women in this high risk group who are allowed to labour. The implications of these findings are discussed.
    Matched MeSH terms: Pregnancy; Pregnancy Complications/mortality; Pregnancy Complications/epidemiology*; Pregnancy Outcome/epidemiology
  11. Omar K, Hasim S, Muhammad NA, Jaffar A, Hashim SM, Siraj HH
    Int J Gynaecol Obstet, 2010 Dec;111(3):220-3.
    PMID: 20800837 DOI: 10.1016/j.ijgo.2010.06.023
    OBJECTIVE: To assess the outcomes and risk factors of adolescent pregnancies in 2 major hospitals in Malaysia.
    METHODS: We conducted a case-control study of pregnant girls aged 10 through 19 years. The controls were women aged 20 through 35 years who did not become pregnant in their adolescence. Cases and controls were matched for parity and place of delivery. Data were collected from questionnaires and the hospitals' medical records.
    RESULTS: The study included 102 cases and 102 controls. There were significant associations between adolescent pregnancy and low education level, low socioeconomic status, being raised by a single parent, not engaging in extracurricular school activities, engaging in unsupervised activities with peers after school, and substance abuse (P<0.05 for all); being anemic, being unsure of the expected delivery date, and having few antenatal visits and a late delivery booking; and low Apgar scores and perinatal complications.
    CONCLUSION: Adolescent pregnancies are high-risk pregnancies. Better sexual health strategies are required to address the associated complications.
    Matched MeSH terms: Pregnancy; Pregnancy Complications/epidemiology; Pregnancy in Adolescence/prevention & control; Pregnancy in Adolescence/statistics & numerical data*; Pregnancy Outcome/epidemiology*; Pregnancy, High-Risk
  12. Fadzil A, Balakrishnan K, Razali R, Sidi H, Malapan T, Japaraj RP, et al.
    Asia Pac Psychiatry, 2013 Apr;5 Suppl 1:7-13.
    PMID: 23857831 DOI: 10.1111/appy.12036
    Anxiety and depression are prevalent during pregnancy. Estimates of the prevalence of anxiety and depression during pregnancy vary according to the criteria used, variable methodologies and population characteristics.
    Matched MeSH terms: Pregnancy; Pregnancy Complications/etiology; Pregnancy Complications/epidemiology; Pregnancy Complications/psychology*
  13. Singh HJ, Saleh HI, Gupalo S, Omar E
    Sheng Li Xue Bao, 2013 Apr 25;65(2):149-57.
    PMID: 23598870
    Although melatonin supplementation is known to influence numerous physiological functions, little is however known of its effects on pregnancy outcome. This study investigated the effects of melatonin supplementation on pregnancy outcome in Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rats aged 12-13 weeks. Upon confirmation of proestrus, each female rat was housed overnight with a male of the same strain. On the next morning, following confirmation of mating (vaginal smear), WKY female rats were isolated into individual metabolic cages and given 0, 25, 50 or 100 mg/kg per day of melatonin in drinking water from day 1 of pregnancy to day 21 postpartum. SD females were given 0 or 100 mg/kg per day of melatonin. Maternal weight, duration of pregnancy, litter size, birth weight and body weight of pups up to day 42, and pup mortality were recorded. Data were analyzed using ANOVA for repeated measures. Compared to controls, maternal weight gain during pregnancy was significantly lower in melatonin-supplemented dams (P < 0.01). Litter size was significantly smaller in melatonin-supplemented dams (P < 0.01). Mean birth weight of pups was significantly lower only in pups of dams given 100 mg/kg per day of melatonin (P < 0.001). Mean body weight of pups of dams given melatonin was significantly lower than controls (P < 0.01). Pup mortalities were 9.5% and 21.6% in WKY dams given 25 and 100 mg/kg per day of melatonin respectively, and all pup deaths occurred after day 21 of weaning. The results suggest that melatonin supplementation during antenatal and postpartum period appears to adversely affect litter size, pup growth and mortality in WKY and SD rats. The precise mechanism causing the death is not clear.
    Matched MeSH terms: Pregnancy; Pregnancy Outcome*; Pregnancy, Animal/drug effects*
  14. Chee KH, Azman W
    Int J Clin Pract, 2009 May;63(5):722-5.
    PMID: 18028390
    Peripartum cardiomyopathy (PPCM) is an uncommon form of congestive heart failure, afflicting obstetric patients around the time of delivery. The epidemiology of PPCM is infrequently reported. To the best of our knowledge, there has been no report from Asia.
    Matched MeSH terms: Pregnancy; Pregnancy Complications, Cardiovascular/epidemiology*; Pregnancy Outcome/epidemiology
  15. Teng HC, Kumar G, Ramli NM
    Br J Radiol, 2007 Jul;80(955):e134-6.
    PMID: 17704308
    Pre-natal diagnosis of intra-abdominal pregnancy is difficult. Ultrasound has been the frontline modality to date; however, it gives a diagnostic error of 50-90% and its use is disappointing. In recent years, MRI has emerged as an appealing imaging modality. With its good soft tissue contrast and non-ionizing property, it acts as a means of definitive non-invasive assessment before surgical intervention when ultrasound is inconclusive.
    Matched MeSH terms: Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Third; Pregnancy, Abdominal/diagnosis*
  16. Omar MH, Mashita MK, Lim PS, Jamil MA
    J Steroid Biochem Mol Biol, 2005 Dec;97(5):421-5.
    PMID: 16293412
    To determine whether therapy with dydrogesterone in threatened abortion during the first trimester of pregnancy will improve pregnancy outcome.
    Matched MeSH terms: Pregnancy; Pregnancy Outcome*; Pregnancy Trimester, First; Pregnancy Trimester, Second
  17. Yong HY, Mohd Shariff Z, Koo SJ, Binti Sa'ari NS
    J Obstet Gynaecol Res, 2016 Sep;42(9):1094-101.
    PMID: 27226139 DOI: 10.1111/jog.13039
    AIM: Both inadequate and excessive weight gain during pregnancy can have immediate and long-term health risks for women and infants. This study investigated rate of gestational weight gain (GWG) and its associated factors in Malaysian pregnant women.
    METHODS: This cross-sectional study was conducted at maternal and child health clinics in Selangor and Negeri Sembilan between November 2010 and April 2012. A pre-tested questionnaire was used to obtain sociodemographic, obstetric, dietary intake and physical activity information. Current weight and height were measured using standard procedures. GWG rate was calculated as the average weekly weight gain in that particular trimester of pregnancy and further categorized according to the Institute of Medicine (IOM) recommendations.
    RESULTS: Mean GWG rate for all pre-pregnancy BMI categories in the second and third trimesters was higher than the IOM recommendations. Overweight women (adjusted OR, 4.26; 95%CI: 1.92-9.44) and women <153 cm tall (adjusted OR, 1.96; 95%CI: 1.21-3.18) tend to have inadequate GWG rate. Women with high pre-pregnancy body mass index (BMI; ≥25.0 kg/m(2) ; overweight: adjusted OR, 3.88; 95%CI: 2.12-7.09; obese: adjusted OR, 2.34; 95%CI: 1.28-4.29) and low physical activity (adjusted OR, 1.74; 95%CI: 0.77-3.97) were two-threefold more likely to have excessive GWG.
    CONCLUSION: Both inadequate and excessive GWG can have detrimental effects on the health of mothers and infants. Pre-pregnancy BMI, height and physical activity should be emphasized in prenatal care to ensure that women have adequate GWG rate.
    Study site: maternal and child health clinics (Klinik Kesihatan), Selangor and Negeri Sembilan, Malaysia
    Matched MeSH terms: Pregnancy; Pregnancy Complications/epidemiology*; Pregnancy Trimester, Second; Pregnancy Trimester, Third
  18. Ng BK, Lim PS, Ahmad S, Kampan NC, Abdul Karim AK, Omar MH
    Taiwan J Obstet Gynecol, 2015 Apr;54(2):208-10.
    PMID: 25951734 DOI: 10.1016/j.tjog.2014.11.022
    Matched MeSH terms: Pregnancy; Pregnancy, Ectopic/drug therapy; Pregnancy, Ectopic/etiology; Pregnancy, Ectopic/ultrasonography*
  19. Ariza M, Rafaee T, Adeeb N, Muhaizan WM, Isa MR
    Med J Malaysia, 1999 Sep;54(3):371-3.
    PMID: 11045067
    A 14 year old girl presented in 1986 with a huge perineal swelling which was progressively increasing in size and associated with loss of weight and loss of appetite. Biopsy from the mass revealed rhabdomyosarcoma of the vulva. She was treated with chemotherapy and radium implant. She responded well to the regime. Fibrosis of the vulva and vagina caused difficulty in consummation. Once it was corrected, she conceived easily and proceeded to a normal pregnancy and delivery.
    Matched MeSH terms: Pregnancy; Pregnancy Complications, Neoplastic*; Pregnancy Outcome*
  20. Ramzisham ARM, Sagap I, Ismail AM
    Med J Malaysia, 2003 Mar;58(1):125-7.
    PMID: 14556338
    Bleeding into the rectus sheath is an uncommon but a well-recognised condition that mimics several other diagnoses of acute abdomen. A wide range of etiology has been proposed in association with this condition. It is often self-limiting, but can lead to unnecessary laparotomy if the diagnosis is not recognised.
    Matched MeSH terms: Pregnancy; Pregnancy Complications/diagnosis*; Pregnancy Complications/etiology*; Pregnancy Complications/therapy
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