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Fulltext Which is a better anthropometric indicator of cardiovascular risk factors in type 2 diabetes mellitus patients? Waist hip ratio or body mass index?

Koo, H.C., S, Daniel Robert, Hamid Jan

Malays J Nutr, 2013;19(2):163-172.
MyJurnal

Introduction: The increasing prevalence of adiposity is associated with the development of type 2 diabetes mellitus (T2DM). The two most popular methods to measure adiposity are body mass index (BMI) and waist-hip-ratio (WHR), which measure the overall and abdominal adiposity, respectively. The aim of this study was to determine whether BMI or WHR was more strongly associated with macronutrient intakes and lipid profiles in T2DM patients. Methods: In this cross-sectional study, a total of 210 T2DM patients, mean age of 56.73(SD 10.23) years, were recruited from Penang. Information on socio-demographic, body measurements (height, weight, waist circumference and hip circumference)and macronutrient intakes (three 24-hour dietary recalls) were recorded. Routine laboratory tests (fasting blood glucose, HbA1c, LDL, HDL, triglyceride and total cholesterol) were performed according to standard procedure. Results:Among the respondents, 84% had abdominal and 63% had overall adiposity respectively.There was a significant correlation between WHR and the total calorie(r=0.27; p
Fulltext Oxidative stress in early life and later obesity development

Loy, S.L., Hamid Jan, J.M., Sirajudeen, K.N.S.

Malays J Nutr, 2013;19(3):383-399.
MyJurnal

Critical time windows exert profound influences on foetal physiological and metabolic profiles, which predispose an individual to later diseases via a 'programming' effect. Obesity has been suggested to be 'programmed' during early life. Foetuses and infants who experience adverse growth are subjected to a higher risk of obesity. However, the key factors that link adverse foetal growth and obesity risk remain obscure. To date, there is considerable evidence showing that the overall balance between free radical damage and the anti.oxidative process being challenged occurs throughout gestation. With the view that pregnancy is a pro-inflammatory state confronted with enhanced oxidative stress, which possesses similar characteristics to obesity (a chronic inflammatory state with increased oxidative stress), oxidative stress is thus biologically plausibly be proposed as the underlying mechanism between this causal-disease relationship. Oxidative stress could act as a programming cue for the development of obesity by inducing complex functional and metabolic deregulations as well as inducing the alteration of the adipogenesis process. Thereby, oxidative stress promotes adipose tissue deposition from early life onwards. The enhancement of fat accumulation further exaggerates oxidative derangement and perpetuates the cycle of adiposity. This review focuses on the oxidative stress pathways in prenatal and early postnatal stages, from the aspects of various endogenous and exogenous oxidative insults. Because oxidative stress is a modifiable pathway, this modifiability suggests a potential therapeutic target to fight the obesity epidemic by understanding the causal factors of oxidant induction.
Fulltext Association between maternal food group intake and birth size

LOY S, MARHAZLINA M, HAMID JAN J

Sains Malaysiana, 2013;42(11):1633-1640.

Maternal nutrition is one of the dominant factors in determining fetal growth and subsequent developmental health for both mother and child. This study aimed to explore the association between maternal consumption of food groups and birth size among singleton, termed newborns. One hundred and eight healthy pregnant women in their third trimester, aged 19 to 40 years who visited the Obstetrics and Gynecology Clinic of Hospital Universiti Sains Malaysia completed an interviewed-administered, validated semi-quantitative food frequency questionnaire. The maternal socio-demographic, medical and obstetric histories and anthropometry measurements were recorded accordingly. The pregnancy outcomes, birth weight, birth length and head circumference were obtained from the medical records. The data were analyzed using multiple linear regression by controlling for possible confounders. Among all food groups, fruits intake was associated with higher birth weight (p=0.018). None of the food intake showed evident association with respect to birth length while only fruits intake was associated positively with head circumference (p=0.019). In contrast, confectioneries and condiments were associated with lower birth weight (p=0.013 and p=0.001, respectively). Also, condiments appeared to associate inversely with ponderal index (p=0.015). These findings suggest the potential beneficial effects of micronutrient rich food but detrimental effects of high sugar and sodium food on fetal growth. Such an effect may have long term health consequences to the lives of children.
Fulltext Assessment of food security, anthropometric and cognitive function among orang asli children in pahang, Malaysia.

Teh S.C, Yusof, H.M, Asma’, A, Hamid Jan, J.M.

IIUM Medical Journal Malaysia, 2020;19(3):81-91.
MyJurnal

Forest clearing for agriculture plantations and local community settlements may trigger food insecurity, which causes poor development, predominantly in Orang Asli children. This cross-sectional study was conducted to determine the relationships between food security and anthropometric and cognitive function among Orang Asli children in Temerloh, Pahang. Materials and methods:A total of one hundred and sixty-seven children (ages 7 to 11) from five selected Orang Asli villages (Kampung Sungai Enggang, Kampung Penderas, Kampung Pasu, Kampung Lubok Wong, and Kampung Pian) were involved in this study. The food security index was assessed using the Radimer/Cornell Hunger and Food Insecurity Instrument. Anthropometric indices were based on height-for-age and BMI-for-age Z-scores, while cognitive performance was tested using Raven’s Coloured Progressive Matrices (R-CPM). Results:A majority (91.6%) of the respondents reported some kind of food insecurity (12.6% household food insecure, 74.2% individual food insecure, and 4.8% child hunger). Rates of stunting, thinness, and overweight/obesity were 25.8%, 16.2%, and 18.0%, respectively. A majority (46.1%) of the children had average cognitive scores, followed by below average (38.3%) and above average (15.6%), respectively. Height-for-age was significantly associated with cognitive function (p=0.008). Among sociodemographic factors, household size (p=0.007) and household income (p
Fulltext Nutrition knowledge, attitude and practices (NKAP) and health-related quality of life (HRQOL) status among overweight and obese children: an analysis of baseline data from the interactive multimedia-based nutrition education package(IMNEP) study

Wan Putri Elena Wan Dali, Hamid Jan Jan Mohamed, HafzanYusoff

Malays J Nutr, 2017;23(1):17-29.
MyJurnal

Introduction: This randomised school-based controlled study aimed to evaluate the baseline results of nutrition knowledge, attitude, and practice (NKAP), health-related quality of life (HRQoL), and parents’ report of parenting skills (PRPS) among overweight and obese children.

Methods: This study was performed on three intervention groups and one control group. It was conducted among Year Five students from primary schools who had overweight or obese status and were generally healthy without any chronic diseases. The children completed NKAP and child self-report of Pediatric Quality of Life (PedsQoL) questionnaires, while parents completed parent proxy report of PedsQoL and PRPS questionnaires. Descriptive statistics and parametric test in SPSS were utilised.

Results: Out of 139 participants involved in the baseline study, 18.7% and 81.3% were overweight and obese respectively. This study revealed a significantly higher knowledge score among boys (p = 0.016) and among those who lived in urban areas (p = 0.019). The children’s selfreport PedsQoL recorded highest score for Social Functioning domain and lowest score for Emotional Functioning domain. A contradictory finding was obtained from the parent proxy report, where the Physical Functioning domain scored the lowest and the Emotional Functioning domain had the highest score. Notably, some of the findings from PRPS questionnaires completed by their parents were unfavourable.

Conclusions: This study provided prospective evidence of the current status of NKAP, HRQoL among overweight and obese children as well as findings from PRPS among their parents.
The effects of prenatal oxidative stress levels on infant adiposity development during the first year of life

Loy SL, Sirajudeen KN, Hamid Jan JM

J Dev Orig Health Dis, 2014 Apr;5(2):142-51.
PMID: 24847700 DOI: 10.1017/S204017441300055X

Although numerous studies have been conducted to examine the causal factors of childhood obesity, the implications of intrauterine oxidative stress on early postnatal adiposity development remain to be elucidated. The Universiti Sains Malaysia Birth Cohort Study aimed to investigate the effects of prenatal oxidative stress levels on the development of infant adiposity during the first year of life. This study was conducted on the healthy pregnant women aged 19-40 years, from April 2010 to December 2012 in Kelantan, Malaysia. Maternal blood samples were drawn in the second trimester to analyse for oxidative stress markers. Infant anthropometric measurements were taken at birth, 2, 6 and 12 months of age. A total of 153 pregnant women and full-term infants were included in the analysis. Statistical test was conducted by using multiple linear regression. Through the infant first year of life, as maternal DNA damage level in the second trimester increased, infant weights at birth (β=-0.122, P<0.001), 2 months (β=-0.120, P=0013), 6 months (β=-0.209, P=0.003) and 12 months of age (β=-0.241, P=0.006) decreased after adjusting for confounders. Similar results were noted when infant body mass index-for-age Z-scores and triceps skinfold-for-age Z-scores were used as the adiposity indicators. In conclusion, the present study shows a consistent inverse association between maternal DNA damage and infant adiposity during the first year of life. These infants with reduced growth and adiposity in early postnatal life may have a high tendency to experience catch-up growth during childhood, which could be strongly associated with later obesity.
Higher intake of fruits and vegetables in pregnancy is associated with birth size

Loy SL, Marhazlina M, Azwany YN, Hamid Jan JM

Southeast Asian J. Trop. Med. Public Health, 2011 Sep;42(5):1214-23.
PMID: 22299448

Maternal nutrition has a programming effect on fetal growth. This cross-sectional study investigated the association between maternal micronutrient, fruit and vegetable intake with birth size. Nutrient and food intake were examined using a validated semi-quantitative food frequency questionnaire. One hundred twenty-one pregnant women at 28 to 38 weeks gestation aged 19-40 years, were recruited from the Universiti Sains Malaysia Hospital, Malaysia. Birth weight, length and head circumference were obtained from the medical records. Data were analyzed using multiple linear regression. Results indicate no significant association between any of the measured micronutrients and birth size. However, 2 of the 6 vegetable subgroups and those consumed fruit during pregnancy had children whose birth size was significantly associated with consumption. An increase of 10 g of leafy vegetables per day was associated with a 1.78 cm increase in head circumference (p = 0.04), and tuber vegetable intake was associated with birth length (beta = 0.21, p = 0.03) and head circumference (beta = 0.21, p = 0.01). Fruit intake was associated with birth weight (beta = 0.19, p = 0.04), birth length (beta = 0.20, p = 0.04) and head circumference (beta = 0.19, p = 0.03). The lack of association between maternal nutrient intake and fetal growth and the significant association between fruit and vegetable intake and birth size suggests the existence of other micronutrients and phytochemicals present in foods that play an important role in birth size. The types of nutrients and their roles in birth size warrant further investigation.
Fulltext Association of Iron Deficiency with or without Anaemia and Cognitive Functions among Primary School Children in Malaysia

Hamid Jan JM, Amal KM, Rohani A, Norimah AK

Malays J Nutr, 2010 Aug;16(2):261-70.
PMID: 22691931 MyJurnal

Iron deficiency and anaemia affect millions of children worldwide. This study aimed to investigate the effect of iron deficiency with or without anaemia on cognitive functions, specifically with short-term memory, attention and visual motor coordination in children. A total of 173 primary school children was enrolled. Cognitive functions were assessed using the Wechsler Intelligence Scale for Children. Three sub-tests were selected to assess processing speed (coding test), immediate auditory memory (digit span test) and visual processing and problem solving ability (maze test). The results showed significant correlation between age and coding test (r =0.38, p< 0.001), digit span test (r =0.16, p = 0.028), and maze test scores (r =0.28, p< 0.001), and the total sub-test scores (r=0.43, p < .001). After age adjustment of the cognitive function tests, iron deficient children without anaemia scored significantly lower than the healthy children (p< 0.001) on coding test, while iron deficient children with anaemia and iron deficient children without anaemia scored significantly lower (p< 0.001) than the healthy counterparts on maze test. No significant differences were observed on digit-span score among the groups. This study confirms the negative effect of both iron deficiency and iron deficiency anaemia on processing speed and visual motor coordination in children.
Associations between prenatal nicotine exposure, oxidative stress, and postpartum visceral fat

Loy SL, Jan Mohamed HJ

Women Health, 2014;54(2):145-60.
PMID: 24329183 DOI: 10.1080/03630242.2013.870632

This study aimed to examine the associations among prenatal nicotine exposure, oxidative stress, and postpartum visceral fat among women exposed to secondhand smoke (SHS). The study was conducted in Kelantan, Malaysia, from April 2010 to December 2012. Blood samples were collected in the second and third trimesters from 135 healthy pregnant women who were followed-up at delivery, 2 months, 6 months and 12 months postpartum. Maternal hair nicotine and oxidative stress markers during pregnancy were measured. Visceral fat was assessed by bioelectrical impedance. Multiple linear regression analysis revealed that maternal hair nicotine concentration was associated with increased DNA damage (tail moment: β=0.580, p=0.001) and decreased glutathione peroxidase (β=-12.100; p=0.009) in the second trimester of pregnancy. Increased DNA damage, protein oxidation and total antioxidant capacity in the second trimester were associated with 2, 6, and 12 months postpartum visceral fat. No direct association was found between prenatal hair nicotine level and postpartum visceral fat; however, these results suggest that any relation of SHS to visceral adiposity may be indirect, mediated via enhanced oxidative stress.
Relative validity of dietary patterns during pregnancy assessed with a food frequency questionnaire

Loy SL, Jan Mohamed HJ

Int J Food Sci Nutr, 2013 Sep;64(6):668-73.
PMID: 23594439 DOI: 10.3109/09637486.2013.787398

This study aimed to assess the relative validity of maternal dietary patterns derived from a semi-quantitative food frequency questionnaire (FFQ). A total of 162 pregnant women aged 19-40-years-old were enrolled from the Universiti Sains Malaysia (USM) Birth Cohort Study in year 2010 and 2011. The FFQ was compared with three 24-h dietary recalls (DRs). Two major dietary patterns were derived from the principle component analysis which are labeled as Healthy and Less-Healthy patterns. The Pearson correlation coefficients between FFQ and DRs for Healthy and Less-Healthy patterns were 0.59 and 0.63, respectively. At least 45% of the participants were correctly classified into the same third from the FFQ and DR for both dietary patterns. The weighted kappa showed moderate agreement for Healthy pattern while good agreement for Less-Healthy pattern between these two dietary assessment methods. Our results indicate reasonable validity of the dietary patterns identified from the FFQ in pregnant women.
Increase in maternal adiposity and poor lipid profile is associated with oxidative stress markers during pregnancy

Loy SL, KNS S, JM HJ

Prev Med, 2013;57 Suppl:S41-4.
PMID: 23219759 DOI: 10.1016/j.ypmed.2012.11.021

This study aimed to evaluate changes in maternal adiposity and lipid profile and to correlate these parameters with Deoxyribonucleic acid (DNA) damage and total antioxidant capacity (TAC) levels among pregnant women.
Fulltext Perception of family satisfaction with care at critical care setting Hospital University Sains Malaysia: a pilot study

Mahyiddin NS, Mohamed R, Jan Mohamed HJ

The Malaysian Journal of Nursing, 2015;7(1):32-37.
MyJurnal

Family members' satisfaction has become an important measurement in determining the quality of care of patients in the critical care setting. The aims of the study were to determine the satisfaction level of family members, to determine the reliability of family satisfaction and its subscales, to identify mean of each question and their subscales. A cross-sectional study was conducted on 30 family members who accompanied patients during intensive care admission. The study was conducted in a critical care setting in
a high dependency unit (HDU) and cardiac intensive care unit (CCU), Hospital University Sains Malaysia (Hospital USM). The data was collected from October 2012 to January 2013. The Critical Care Family Satisfaction Survey (CCFSS) Malay version was used to measure family satisfaction in addition to the collection of demographic data. The statistical analysis used a descriptive approach. Ethical approval was obtained prior to data collection. Majority of the respondents were female: 23 (76.7%). Mean age was 35.67 years (SD=12.83) and the score of overall satisfaction level was 78.80 (SD=13.88). The Cronbach's alpha was 0.96. A majority of the respondents, 19 (63.3%) were satisfied with the care provided. This study showed that a majority of family members were slightly satisfied with the care that was provided in a critical
care setting at HUSM. It also showed that families play an important role in giving support and hope to patients.
Study site: HDU and CCU, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia
Fulltext Validation and reproducibility of a culturally specific food frequency questionnaire (FFQ) for Malaysian Punjabis

Satvinder Kaur, Hip, Seng Yim, Hamid Jan Jan Mohamed, Rohana Abdul Jalil, Barakatun-Nisak Mohd. Yusof

Malays J Nutr, 2016;22(2):245-255.
MyJurnal

Introduction: Validation of a culturally specific FFQ is important in assessing habitual dietary intake of ethnic population groups. This study aimed to assess the validity and reproducibility of a FFQ developed specifically for determining the dietary intake of Malaysian Punjabis.

Methods: Subjects were approached through voluntary participation for the development and validation phase in the Klang Valley. A list of foods consumed by participants (n=100) was documented through a 3-day dietary recall. The validation process was conducted by verifying the developed FFQ against another group of Punjabi adult volunteers (n=101) who kept a 2-day dietary record. Macronutrients, dietary fibre, fatty acids, cholesterol, three types of minerals (calcium, sodium, iron) and four vitamins (B12, folate, C, A) were included in the analysis. Reproducibility was shown with intraclass correlation (ICC) values between FFQ1 vs FFQ2 that were administered 6 months apart among 32 participants.

Results: In the validation study, the FFQ1 was found to have over-estimated almost all nutrients compared to those in the dietary records. The Spearman correlation coefficients for energy, carbohydrate, protein and fat intake based on the FFQ1 and 2-day dietary records were 0.54, 0.38, 0.47, and 0.31, respectively. The classification into the same and adjacent quartiles was between 61- 84% for the nutrients consumed. Bland Altman plots showed relatively good agreement (between ±2 standard deviation) for both the dietary methods used. Reproducibility analysis of ICC (FFQ1 vs FFQ2) was between 0.46-0.76 for macronutrients and 0.20-0.92 for micronutrients.

Conclusion: The developed FFQ could be used as a valid tool for assessing dietary intake of Malaysian Punjabis, as it showed a moderate agreement with dietary record for intake of energy and macronutrients.
Fulltext High knowledge on dengue but low preventive practices among residents in a low cost flat in Ampang, Selangor

Nur Syakilah Mahyiddin, Rosmawati Mohamed, Hamid Jan Jan Mohamed, Norfarhana Ramly

The Malaysian Journal of Nursing, 2016;8(1):39-48.
MyJurnal

Dengue incidence has grown dramatically in recent decades and become a global incidence especially in the
urban area. Ministry of Health (MOH) Malaysia reported that the number of dengue cases since January
2014 until June 2014 was 38. 411 cases which was higher compared to the number reported in year 2013 (10,
910 cases). The objective of the study was to determine the knowledge and preventive practices of dengue
among residents in Flat Pandan Indah, Ampang Selangor. A cross sectional study design with convenience
sampling method was adopted in this study. A total of 298 respondents living in Flat Pandan Indah were
recruited based on the inclusion criteria. A validated questionnaire that measures knowledge and preventive
practices of dengue was completed by respondents. More than half of the respondents had scored 61.7%
with good knowledge regarding dengue. However, 50.3% of the respondents had a limited extent of dengue
practice. Almost all of the respondents (95.6%) reported that television or radio as the main source for
information on dengue. The common preventive measures used by the respondents were cleaning the
house (n=148, 49.7%), eliminating standing water around the house (n=123, 41.3%) and covering water
containers in the home (n=120, 40.a3%). There was no correlation between dengue knowledge and
preventive practice score (p = 0.109). The study revealed that majority of the respondents had good
knowledge regarding dengue but the practices to prevent dengue are poor. Thus, health education program
focusing on dengue prevention practices should be done on the community members in the future.
Fulltext Maternal serum and breast milk vitamin D levels: findings from the Universiti Sains Malaysia Pregnancy Cohort Study

Jan Mohamed HJ, Rowan A, Fong B, Loy SL

PLoS One, 2014;9(7):e100705.
PMID: 24992199 DOI: 10.1371/journal.pone.0100705

Vitamin D deficiency has become a global health issue in pregnant women. This study aimed to assess the adequacy of maternal vitamin D status by measuring maternal serum and breast milk 25-hydroxyvitamin D [25(OH)D] levels and to determine the association between maternal serum and milk 25(OH)D levels.
Fulltext Plasma adiponectin concentrations are associated with dietary glycemic index in Malaysian patients with type 2 diabetes

Loh BI, Sathyasuryan DR, Mohamed HJ

Asia Pac J Clin Nutr, 2013;22(2):241-8.
PMID: 23635368 DOI: 10.6133/apjcn.2013.22.2.04

Adiponectin, an adipocyte-derived hormone has been implicated in the control of blood glucose and chronic inflammation in type 2 diabetes. However, limited studies have evaluated dietary factors on plasma adiponectin levels, especially among type 2 diabetic patients in Malaysia. The aim of this study was to investigate the influence of dietary glycemic index on plasma adiponectin concentrations in patients with type 2 diabetes. A cross-sectional study was conducted in 305 type 2 diabetic patients aged 19-75 years from the Penang General Hospital, Malaysia. Socio-demographic information was collected using a standard questionnaire while dietary details were determined by using a pre-validated semi-quantitative food frequency questionnaire. Anthropometry measurement included weight, height, BMI and waist circumference. Plasma adiponectin concentrations were measured using a commercial ELISA kit. Data were analyzed using multiple linear regression. After multivariate adjustment, dietary glycemic index was inversely associated with plasma adiponectin concentrations (β =-0.272, 95% CI -0.262, - 0.094; p<0.001). It was found that in individuals who consumed 1 unit of foods containing high dietary glycemic index that plasma adiponectin level reduced by 0.3 μg/mL. Thirty two percent (31.9%) of the variation in adiponectin concentrations was explained by age, sex, race, smoking status, BMI, waist circumference, HDL-C, triglycerides, magnesium, fiber and dietary glycemic index according to the multiple linear regression model (R2=0.319). These results support the hypothesis that dietary glycemic index influences plasma adiponectin concentrations in patients with type 2 diabetes. Controlled clinical trials are required to confirm our findings and to elucidate the underlying mechanism.
Fulltext The prevalence of metabolic syndrome according to various definitions and hypertriglyceridemic-waist in Malaysian adults

Zainuddin LR, Isa N, Muda WM, Mohamed HJ

Int J Prev Med, 2011 Oct;2(4):229-37.
PMID: 22174962

OBJECTIVES: Metabolic syndrome can be diagnosed according to several different criteria such as the latest International Diabetes Federation (IDF), National Cholesterol Education Program Adult Treatment Program III (NCEP ATPIII), and World Health Organization (WHO). The objectives of this study were to determine the prevalence of metabolic syndrome and the concordance between the above mentioned definition, and hypertriglyceridemic-waist criteria.
METHODS: This cross sectional study was done in Bachok, Malaysia and involved 298 respondents aged between 18 to 70 years. Multistage random sampling method was used to identify study locations while convenient random sampling method was applied to select individuals. Hypertriglyceridemic waist was defined from an internationally acceptable cut-off criterion. Kappa statistic (κ test) was used to determine the concordance between various definitions and hypertriglyceridemic-waist.
RESULTS: The prevalence of metabolic syndrome based on different definitions was 32.2% (IDF), 28.5% (NCEP ATP III) and 12.4% (modified WHO). The prevalence of hypertriglyceridemic-waist was 19.7% and based on the IDF criteria a total of 97.5% participants with hypertriglyceridemic-waist had metabolic syndrome. The IDF criteria showed the highest concordance with NCEP ATPIII criteria (κ = 0.63), followed by hypertriglyceridemic-waist criteria (κ = 0.62) and WHO criteria (κ = 0.26).
CONCLUSIONS: The prevalence of metabolic syndrome was highest using the IDF criteria compared to NCEP ATPIII, modified WHO and hypertriglyceridemic-waist. There was a good concordance of IDF criteria with NCEP ATP III and hypertriglyceridemic-waist criteria.
KEYWORDS: Hypertriglyceridemic-waist; Malaysia; Metabolic syndrome
Leptin and calorie intake among different nicotine dependent groups

Suhaimi MZ, Sanip Z, Jan HJ, Yusoff HM

Ann Saudi Med, 2016;36(6):404-408.
PMID: 27920412

BACKGROUND: Exposure to nicotine via tobacco smoking may influence leptin release and decrease food intake among smokers. However, the effect of nicotine exposure on leptin and food intake among different nicotine dependent groups is unclear.
OBJECTIVE: We aimed to measure leptin and calorie intake among different nicotine dependent groups.
DESIGN: Cross-sectional study.
SETTING: Research department in school of medical sciences.
PATIENTS AND METHODS: Subjects were selected by purposive (non-probability) sampling and categorized as having low, moderate and high nicotine dependency based on the Fagerstrom Test for Nicotine Dependence (FTND) score. Diet was recorded by interview. Anthropometry, blood pressure, body composition, lipid profile, and physical activity level were measured accordingly. Fasting serum leptin was measured using a commercial ELISA kit.
MAIN OUTCOME MEASURE(S): Nicotine dependency, 24-hour diet, clinical anthropometric and clinical measurements.
RESULTS: In 107 Malay male smokers leptin concentration was inversely correlated with nicotine dependence. However, body weight, smoking period, blood pressure, body composition, lipid profile and physical activity level were not significantly different among low, moderately and highly dependent smoking groups. Leptin concentration and total calorie intake were also not significantly different among these groups.
CONCLUSION: Leptin concentration was inversely correlated with nicotine dependence, but leptin concentration and total calorie intake status were not significantly different among our different nicotine dependency subjects.
LIMITATIONS: Purposive sampling for subject recruitment and inaccurate information in the self-administered questionnaire.
Nutrient Intakes Status and Physical Inactivity among Overweight and Obese School Children in Kota Bharu, Kelantan, Malaysia

Wan Dali WPE, Jan Mohamed HJ, Yusoff H

Iran J Public Health, 2018 Aug;47(8):1098-1107.
PMID: 30186781

Background: The study examined the baseline findings of a controlled intervention study comprising anthropometric measurements, nutrient intakes, and physical activity among overweight or obese children in Kota Bharu, Kelantan, Malaysia.
Methods: The study was completed in 2016 and the baseline data were gathered from four groups in a school-based randomized community trial among Year Five students from primary schools in Kota Bharu, Kelantan, Malaysia. Participants completed anthropometry assessment, three-day dietary record, and Physical Activity Questionnaire for Older Children (PAQ-C).
Results: The prevalence of obesity was higher among the boys (52.5%). Mean energy intake was significantly higher among boys as compared to the girls (P=0.003). Twenty-five percent of the participants had exceeded the recommended nutrient intakes (RNI) of energy recommended. The calcium, thiamine, riboflavin, and niacin were also significantly higher among boys as compared to the girls (P<0.05). Boys also exhibited a significantly higher score on performance of physical activity (mean=2.68; SD=0.60) as compared to the girls (mean=2.38; SD=0.51) however it is still in the category of moderately active. Approximately 14.4% of children had a very low physical activity level.
Conclusion: Overweight and obese boys had higher energy and fat intakes but were more physically active as compared to the girls. These findings might be useful in planning appropriate intervention strategies to be designed and delivered especially for this cohort.
Fulltext Development, validity and reliability of a pregnancy symptoms questionnaire (PSQ)

Marhazlina Mohamad, Loy, See-Ling, Nik Mohamed Zaki Nik Mahmood, Nor Azwany Yaacob, Hamid Jan Jan Mohamed

Jurnal Sains Kesihatan Malaysia, 2011;9(2):15-21.
MyJurnal

This study aimed to develop and examine the validity and reliability of a pregnancy symptoms questionnaire. A total of 214 pregnant women aged 19 to 40 years old were purposive randomly recruited from December 2009 to January 2010 in Antenatal Clinic, Hospital Universiti Sains Malaysia. Pregnant mothers at second and third trimesters were interviewed to complete the Pregnancy Symptoms Questionnaire (PSQ). The PSQ was developed by experts in nutrition, obstetrics and statistics. The PSQ consists of 38 items on frequency and severity of pregnancy symptoms. Factor analysis was done using Promax rotation method to check for construct validity. A total of 16 items which had poor correlation (<0.3) and less important content were removed during the final revise. The 22 remaining items were found to be loaded on the three components (general, constitutional and somatic pain). The overall Cronbach’s alpha coefficient was 0.93 and for each three components ranges from 0.70–0.87. The results suggest that the final PSQ consisting of 22 items is valid and reliable for measuring the frequency and severity of the symptoms experienced during pregnancy. It can be used in nutritional studies related to pregnancy and its outcome.
Keywords: Pregnant mothers; Pregnancy symptoms; Questionnaire; Validation
Study site: Antenatal Clinic, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia

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