Displaying publications 1 - 20 of 209 in total

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  1. Zhao J, Liu E
    Front Psychol, 2022;13:1031615.
    PMID: 36578679 DOI: 10.3389/fpsyg.2022.1031615
    INTRODUCTION: In 2020, COVID-19 forced higher education institutions in many countries to turn to online distance learning. The trend of using online education has accelerated across the world. However, this change in the teaching mode has led to the decline of students' online learning quality and resulted in students being unable to do deep learning. Therefore, the current research, aimed at promoting deep learning in the online environment, constructed a theoretical model with learning self-efficacy and positive academic emotions as mediators, deep learning as the dependent variable, perceived TPACK support, peer support, technical usefulness, and ease of use as independent variables.

    METHODS: The theoretical model was verified by SPSS26.0 and smartPLS3.0, and to assess the measurement and structural models, the PLS approach to structural equation modeling (SEM) was performed.

    RESULTS: The study found that (a) positive academic emotions play a mediating role between perceived TPACK support and deep learning, perceived peer support and deep learning, and perceived technology usefulness and ease of use and deep learning; (b) learning self-efficacy plays a mediating role between perceived TPACK support and deep learning, perceived peer support and deep learning, and perceived technology usefulness and ease of use and deep learning.

    DISCUSSION: The findings of this study fill the gaps in the research on the theoretical models of deep learning in the online environment and provide a theoretical basis for online teaching, learning quality, and practical improvement strategies.

  2. Zhao J, Qin Y
    Front Psychol, 2021;12:652796.
    PMID: 34234709 DOI: 10.3389/fpsyg.2021.652796
    The purpose of this research is to test the mediation effect of self-efficacy on college student's perception of teacher autonomy support and students' deep learning, and whether the peer support perceived by students can moderate the relationship between perceived teacher autonomy support and deep learning. A survey of 1,800 college students from a provincial undergraduate normal university in Guizhou Province in China was conducted through the revised Perceived Teacher Autonomy Support Scale, Deep Learning Scale, Self-Efficacy Scale, and Perceived Peer Support Scale (Mean age = 21 years old, SD = 1.34). Data use SPSS23.0, AMOS22.0 for descriptive analysis and correlation analysis, exploratory factor analysis (EFA) and confirmatory factor analysis (CFA), moderation effect, and mediation effect analysis. The research results show that after controlling for gender, major, and grade, self-efficacy partially moderates the connection between perceived teacher autonomy support and deep learning of college students. Moreover, perceived peer support mediates the relationship between perceived teacher autonomy support and students' self-efficacy.
  3. Liu E, Zhao J, Sofeia N
    Front Psychol, 2021;12:793548.
    PMID: 35095678 DOI: 10.3389/fpsyg.2021.793548
    In recent years, deep learning as the requirement of higher education for students has attracted the attention of many scholars, and previous studies focused on defining deep learning as the deep processing of knowledge of the brain, however, in the process of knowledge processing, the brain not only involves the deep processing of information but also participates in learning consciously and emotionally. Therefore, this research proposed a four-factor model hypothesis for deep learning that includes deep learning investment, deep cognitive-emotional experience, deep information processing, and deep learning meta-cognitive. In addition, the research proposed teachers' emotional support perceived by students has an effect on the four factors of deep learning. Through SPSS 26 and AMOS 24, this research has verified the four-factor model of deep learning applying exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) and verified that the perceived teacher emotional support has an impact on the four factors of students' deep learning using the SEM.
  4. Zhao J, Virani S, Sriplung H
    Health Policy Plan, 2017 Apr 01;32(3):430-436.
    PMID: 27935803 DOI: 10.1093/heapol/czw145
    Background: The national cervical cancer screening program in Thailand has been successful in reducing overall burden from this disease. However, evaluation on spatial and temporal scales is needed to assess the efficacy of this program in smaller regions. Here, we geographically assess incidence in a province with a uniquely heterogeneous distribution of lifestyle factors associated with religiosity.

    Methods: Cervical cancer cases were extracted from the provincial cancer registry from 1989 to 2013. Age-adjusted incidence rates were calculated using population statistics from the census bureau and adjusted to the Segi world standard population. Bayesian hierarchical modelling was employed to spatiotemporally map cervical cancer incidence trends in Songkhla province in 5-year period.

    Results: Overall, the incidence of cervical cancer decreased in Songkhla province. The three districts with a Muslim population of greater than 70% had consistently lower cervical cancer rates from 1989 to 2013 compared with the rest of the predominantly Buddhist districts. Hotspots of incidence were identified in Sadao, Hat Yai and the juncture of Mueang Songkhla and Singhanakhon in each 5-year period.

    Conclusions: Distinct cervical cancer incidence trends by religion over time indicate differences in sexual habits, lifestyle and religion-associated culture between Muslims and Buddhists, and suggest divergent risk factor profiles for these groups. The high incidence rates in Sadao and Hat Yai is likely explained by the main road to Malaysia, which runs across these two areas and has frequent commercial sex trade. Female sex workers should be targeted as a vulnerable population for screening efforts to address this continuing burden of cervical cancer.

  5. Zhao J, Wang C, Ibrahim H, Chen Y
    PLoS One, 2024;19(8):e0309099.
    PMID: 39163358 DOI: 10.1371/journal.pone.0309099
    The use of digital technology by banks and other financial institutions to facilitate financial inclusion is referred to as digital financial inclusion. This fusion of digital finance and traditional banking methods has the potential to impact banks' operational effectiveness. This study uses the panel effects model to examine the link between digital financial inclusion and bank performance in 30 Chinese provinces from 2012 to 2021. This research uses kernel density estimation to examine the spatial-temporal growth patterns of both variables. The mediator variable in examining how digital financial inclusion affects bank performance is risk-taking. Finally, the paper analyses the regional heterogeneity of the impact. It presents the following conclusions: (1) In China, digital financial inclusion and bank performance have constantly increased, with noticeable regional variances in their development levels. This regional inequality has widened gradually since 2018, yet it has not resulted in polarization. (2) The significant positive correlation between digital inclusive finance and banking performance indicates that banking performance tends to increase with the enhancement of digital inclusive finance. (3) Digital financial inclusion impacts bank performance, with risk-taking as a moderator. The spread of digital financial inclusion services enhances banks' willingness to take risks, enhancing overall efficiency. (4) Digital financial inclusion boosts bank performance in the Northwest, South, North, and East regions while lightly inhibiting it in the Central region. Based on the findings, this study makes bank and government suggestions.
  6. Zhao J, Zhao J, Yuan H, Gao Z
    Front Nutr, 2024;11:1501536.
    PMID: 39777071 DOI: 10.3389/fnut.2024.1501536
    BACKGROUND: Weight and body shape concerns have become increasingly common among adolescents. Chinese university students show a high risk of eating disorder behaviors. This study aims to analyze the moderating effect of BMI on the relationships between body shape, attitudes, subjective norms, and eating disorder behavioral intentions among Chinese female university students using the Theory of Reasoned Action (TRA) model.

    METHODS: A stratified random sample of 679 female Chinese university students (age, mean ± SD = 19.792 ± 1.007) participated in the study. The surveys comprised the Theory of Reasoned Action Questionnaire (TRA-Q) and the Body Shape Questionnaire (BS-Q) to assess their body shape concerns and behavioral intentions regarding eating disorders. Structural equation modeling was used to test the extended TRA model, with body shape as an additional predictor and BMI as a moderator.

    RESULTS: Body shape positively affected attitudes (β = 0.444, p 

  7. Zhao J, Tien HY, Abdullah S, Zhang Z
    Plast Reconstr Surg, 2010 Dec;126(6):2052-2059.
    PMID: 21124145 DOI: 10.1097/PRS.0b013e3181f44994
    BACKGROUND: Second toe-to-thumb transfer is a good alternative to using the great toe for reconstruction of the thumb. It achieves excellent function and reduces morbidity to the donor foot. However, cosmesis is often poor. The second toe has three unattractive features, a narrow "neck," a bulbous tip, and a short nail.

    METHODS: The authors describe a modified second toe transfer that addresses cosmesis in six patients. These include (1) harvesting a flap from the adjacent side of the great toe and insetting it into the volar aspect of the second toe to give more bulk, (2) making skin excisions on each side of the tip to reduce the bulbous appearance, and (3) excising the eponychium to produce apparent lengthening of the nail.

    RESULTS: The mean follow-up period was 18 months (range, 6 to 36 months). The procedure resulted in good function and improved cosmesis in all six cases. Part of the great toe flap was lost in one case. The mean two-point discrimination in the transferred toes was 10.1 mm, with protective sensation present in the flaps. The range of motion of the transferred toe was 14 to 38 degrees at the metatarsophalangeal joint, 16 to 55 degrees at the proximal interphalangeal joints, and 20 to 36 degrees in the distal interphalangeal joints. All patients except one were happy with the appearance of the transferred toe.

    CONCLUSION: This novel approach will allow patients to take advantage of the lower morbidity to the donor site afforded by second toe-to-thumb transfer and provide the patients with a more aesthetic appearance of the new thumb.

  8. Zhao J, Xiao J, Lee ML, Ma Y
    Springerplus, 2016;5(1):1633.
    PMID: 27722051
    Slopes are subjected to stress redistributions during underground mining activities, and this may eventually cause deformation or landslide. This paper takes Madaling landslide in Guizhou Province, China as a case study to investigate the failure mechanism and its run-out behaviours by using discrete element method. Previous qualitative analysis indicated that the slope experienced four stages of failure mechanisms: (1) development of tension cracks, (2) development of stepped-like creep cracks, (3) development of potential rupture surfaces, and (4) occurrence of the landslide. PFC2D program was employed to model the pre-failure deformation characteristics in order to verify the failure mechanisms quantitatively. Subsequently, the run-out behaviours of the landslide were analyzed by PFC3D program. The results indicated that the movement could be summarized into four stages: acceleration stage, constant movement stage, rapid movement stage, and deceleration and deposition stage.
  9. Song P, Zhao J, Mubarak SMA, Taresh SM
    Saf Sci, 2022 Jan;145:105498.
    PMID: 34545268 DOI: 10.1016/j.ssci.2021.105498
    Colleges and universities are considered as one of the "main battlefields" of epidemic prevention and control, wherein, they have difficulty in clarifying and identifying the critical points for emergency management due to the complexity and multiplicity of influencing factors. Therefore, this study aims to identify the most effective Critical Success Factors (CSFs) for COVID-19 prevention and control in China. This study uses the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method. This study has finally identified five Critical Success Factors (CSFs), which are 1) the training of emergency management professionals, 2) the cultivation of coordinating abilities, 3) the establishment of an epidemic prevention and control leadership team, 4) the development of corresponding responsibility awareness, and 5) the regulation of online public opinions. By focusing on these five CSFs, it can effectively facilitate colleges and universities to optimize their entire emergency management system in the process of normalization and professionalization of campus emergency management.
  10. Xu P, Sulaiman NAA, Ding Y, Zhao J
    Sci Rep, 2025 Jan 20;15(1):2468.
    PMID: 39833339 DOI: 10.1038/s41598-025-86753-x
    Accurate segmentation of power line targets helps quickly locate faults, evaluate line conditions, and provides key image data support and analysis for the safe and stable operation of the power system.The aerial power line in segmentation due to the target is small, and the imaging reflected energy is weak, so the Unmanned Aerial Vehicle (UAV) aerial power line image is very susceptible to the interference of the environment line elements and noise, resulting in the detection of the power line target in the image of the defective, intermittent, straight line interferences and other low accuracy and real-time efficiency is not high. For this reason, this paper designs a pure amplitude stretching kernel function to form a Fourier amplitude vector field and uses this amplitude vector field to implement the stretching transformation of the amplitude field of the aerial power line image, so that the angular field after the Fourier inverse transformation can better react to the spatial domain line targets, and finally, after the Relative Total Variation (RTV) processing, the power line can be well detected. The proposed algorithm is compared with the main power line segmentation algorithms, such as Region Convolutional Neural Networks(R-CNN) and Phase Stretch Transform(PST). The average values of evaluation indicators PPA, MMPA and MMIoU of the image segmentation results of the proposed algorithm reach 0.96, 0.96 and 0.95 respectively, and the average time lag of detection is less than 0.2s, indicating that the accuracy and real-time performance of the segmentation results of the proposed algorithm are significantly better than those of the above algorithms.
  11. Su J, Zhao JY, Li YF, Lu YJ
    Trop Biomed, 2024 Dec 01;41(4):471-480.
    PMID: 39876505 DOI: 10.47665/tb.41.4.008
    Mosquito-borne diseases have wreaked havoc on human health, with consequences dramatically increasing in recent years. The incidence of mosquito-borne diseases is closely linked to the locations that are chosen for urban development. The aim of this study was to provide characteristics of mosquito breeding sites in northern and southern China and to document the most important arbovirus vectors found in the study area, the evidence generated here is critical for early prevention and control inter ventions. This research involved a random selection of various sites across four provinces, spanning both the northern and southern regions of China. The dwellings and accessible water storage containers in these sites were investigated to detect the presence of immature mosquitoes. Samples were then collected, mosquitoes were nurtured to adulthood, and the species that were present were identified. A total of 1 249 samples were collected during this survey of the mosquito breeding sites. A total of 80 samples were processed using the Chelex method to extract mosquito DNA from all the samples. The ITS2 gene fragment was then amplified by PCR and sequenced. A subsequent BLAST comparison allowed the identification of the mosquito species, and MEGA11 software was used for phylogenetic analysis. The results showed that there were four species of mosquitoes, including Aedes albopictus, Culex quinquefasciatus, Lutzia fuscanus and Armigeres subalbatus. The primary mosquito breeding grounds in the four provinces of China consisted of storm drains, discarded containers, garbage bins, and areas with standing water. Still-water environments, such as rice fields were the primary breeding locations in the southern cities. In contrast, in the northern regions, most breeding occurred at construction sites, and in similar water-prone areas. The most prevalent mosquitoes in the four provinces of China were of the genus Aedes, with a significant number originating from Fujian Province, China. This information sheds light on the migration patterns of mosquitoes and significantly enhances community-based protection measures and mobilization efforts.
  12. Cao X, Liu J, Zhao J, Feng S, Zhao Z
    J Sport Rehabil, 2025 Feb 13.
    PMID: 39947195 DOI: 10.1123/jsr.2024-0160
    Adolescent athletes participating in sports involving sudden directional changes, pivoting, and jumping frequently sustain anterior cruciate ligament (ACL) ruptures. ACL reconstruction (ACLR) surgery is often required, followed by a lengthy rehabilitation period. This study aims to evaluate the effectiveness of combining BOth Sides Up (BOSU) ball exercises with conventional resistance training in the recovery of joint stability and function after ACLR in adolescent athletes. Thirty adolescent athletes (ages 14-18) who underwent ACLR were randomly allocated to either the control group receiving traditional postoperative rehabilitation (n = 15) or the intervention group combining BOSU ball training with resistance exercises (n = 15). Joint stability, proprioception, strength, and functional outcomes were assessed before the procedure, as well as 3, 6, and 12 months after the operation using the KT-1000 arthrometer, Y-balance test, isokinetic dynamometry, and the ACL-Return to Sport after Injury ACL-Return to Sport after Injury (ACL-RSI) scale. The intervention group demonstrated notably better anterior-posterior knee joint stability (P < .05) than the control group at the 6-month and 12-month follow-ups after the surgery, greater reach distances in the Star Excursion Balance Test (P < .05), higher quadriceps and hamstring strength ratios (P < .05), and superior ACL-RSI scores (P < .01). Incorporating BOSU ball training with resistance exercises appears to be more effective than traditional rehabilitation alone in enhancing joint stability and neuromuscular control after ACLR in adolescent athletes. These results provide evidence supporting the incorporation of unstable surfaces into a comprehensive rehabilitation program to optimize recovery and safe return to sports.
  13. Chen J, Li W, Zhao J, Lee YY, Chen J, Wang Y
    Int J Biol Macromol, 2025 Apr;304(Pt 1):140884.
    PMID: 39938842 DOI: 10.1016/j.ijbiomac.2025.140884
    The chitosan-based bone-targeted delivery system was designed to enhance the therapy efficacy of Cyclolinopeptide J (CLJ), a bioactive peptide derived from flaxseed, for the treatment of osteoporosis. The bone-targeting polymer conjugates (CSD8) were prepared via a crosslinking reaction between carboxylated chitosan (CMCS) and functional peptide (ASP8). The CSD8 was then modified on the surface of CLJ-loaded nanoparticles to form novel nanoparticles (JCA/CSD8). The particle size of JCA/CSD8 was 122.40 ± 1.8 nm and the loading capacity of CLJ was 22.7 %. The results showed that the in vitro bone affinity and in vivo bone targeting efficiency of JCA/CSD8 increased 11.7-fold and 13.6-fold, respectively, achieving systemic targeting. Moreover, in vitro studies revealed that JCA/CSD8 could degrade within lysosomes under acidic conditions, thereby releasing CLJ and Ca2+ for synergistically promoting osteogenesis to realize the local targeting. The JCA/CSD8 group increased the transcription levels of osteogenic-related markers, including OPG, ColI, OCN, OPN, RUNX2, and ALP. Furthermore, in vivo studies demonstrated the impressive capability of JCA/CSD8 to increase bone density and restore trabecular bone architecture in the OVX mice model, which was superior to the positive control group. In conclusion, using chitosan-based bone-targeted nanoparticles presents a highly promising and efficient clinical therapy for addressing osteoporosis.
  14. Zhao J, Xiang C, Tengku Fadilah TK, Luo H
    J Sports Sci Med, 2024 Jun;23(2):289-304.
    PMID: 38841637 DOI: 10.52082/jssm.2024.289
    Perception is an essential component of children's psychological development, which is foundational to children's ability to understand and adapt to their external environment. Perception is also a crucial tool for understand and navigating one's surroundings, enabling children to identify objects and react appropriately to settings or situations. Substantial evidence indicates that engaging in physical activity is beneficial for the development of children's perceptual abilities, as the two are closely intertwined. Still, more research is necessary to gain a full understanding of the impact of physical activity on children's perception. To further identify and quantify the effects of physical activity on a number of specific perceptions in children. Systematic review and meta-analysis. Searches were performed using five online databases (i.e., PubMed, SPORTDiscus, PsycINFO, Web of Science, and Cochrane Library) for articles published up to and including June 2023 to identify eligible citations. A total of 12 randomized controlled trials, encompassing 1,761 children under the age of 12, were analyzed. Overall, physical activity as an intervention showed a notable effect on the development of children's perceptions. The meta-analysis indicated that participating in physical activity for 30 minutes around, daily, had a greater impact on children's visual perception and executive functioning than on their motor perception, body perception, and global self-worth (SMD = 1.33, 95% CI: 0.75, 1.91, p < 0.001). The effects of physical activity on children's perception performance varied by participant characteristics, with physical activity having better effects on body perception and overall self-worth in children who were obese or overweight. Furthermore, physical activity can also enhance executive function and attention in children with developmental coordination disorders. The effects of physical activity on children's perception performance varied according to the intervention time, with different activity durations resulting in different perception performances. Therefore, parents and educators must prioritize an appropriate length of physical activity time for children to ensure their optimal growth and development. Registration and protocol CRD42023441119.
  15. Tan L, Wang M, Li X, Li H, Zhao J, Qu Y, et al.
    Bioresour Technol, 2016 Jan;200:572-8.
    PMID: 26539970 DOI: 10.1016/j.biortech.2015.10.079
    In this work, fractionation of empty fruit bunch (EFB) by bisulfite pretreatment was studied for the production of bioethanol and high value products to achieve biorefinery of EFB. EFB was fractionated to solid and liquor components by bisulfite process. The solid components were used for bioethanol production by quasi-simultaneous saccharification and fermentation. The liquor components were then converted to furfural by hydrolysis with sulfuric acid. Preliminary results showed that the concentration of furfural was highest at 18.8g/L with 0.75% sulfuric acid and reaction time of 25min. The conversion of xylose to furfural was 82.5%. Furthermore, we attempted to fractionate the liquor into hemicellulose sugars and lignin by different methods for producing potential chemicals, such as xylose, xylooligosaccharide, and lignosulfonate. Our research showed that the combination of bisulfite pretreatment and resin separation could effectively fractionate EFB components to produce bioethanol and other high value chemicals.
  16. Tan L, Sun W, Li X, Zhao J, Qu Y, Choo YM, et al.
    Biotechnol J, 2015 Jun;10(6):915-25.
    PMID: 25866127 DOI: 10.1002/biot.201400733
    Bisulfite pretreatment is a proven effective method for improving the enzymatic hydrolysis of empty fruit bunch (EFB) from oil palm for bioethanol production. In this study, we set out to determine the changes that occur in the structure and properties of EFB materials and fractions of hemicellulose and lignin during the bisulfite pretreatment process. The results showed that the crystallinity of cellulose in EFB increased after bisulfite pretreatment, whereas the EFB surface was damaged to various degrees. The orderly structure of EFB, which was maintained by hydrogen bonds, was destroyed by bisulfite pretreatment. Bisulfite pretreatment also hydrolyzed the glycosidic bonds of the xylan backbone of hemicellulose, thereby decreasing the molecular weight and shortening the xylan chains. The lignin fractions obtained from EFB and pretreated EFB were typically G-S lignin, and with low content of H units. Meanwhile, de-etherification occurred at the β-O-4 linkage, which was accompanied by polymerization and demethoxylation as a result of bisulfite pretreatment. The adsorption ability of cellulase differed for the various lignin fractions, and the water-soluble lignin fractions had higher adsorption capacity on cellulase than the milled wood lignin. In general, the changes in the structure and properties of EFB provided insight into the benefits of bisulfite pretreatment.
  17. Chang W, Zhao J, Liu L, Xing X, Zhang C, Meng H, et al.
    J Anal Methods Chem, 2021;2021:6661799.
    PMID: 33688447 DOI: 10.1155/2021/6661799
    Nanotechnology is playing a major role in the field of medical diagnosis, in particular with the biosensor and bioimaging. It improves the performance of the desired system dramatically by displaying higher selectivity and sensitivity. Carbon nanomaterial, gold nanostructure, magnetite nanoparticle, and silica substrate are the most popular nanomaterials greatly contributed to make the affordable and effective biosensor at low-cost. This research work is introducing a new sensing strategy with graphene oxide-constructed triangular electrodes to diagnose Alzheimer's disease (AD). MicroRNA-137 (miRNA-137) was found as a suitable biomarker for AD, and the sensing method was established here to detect miRNA-137 on the complementary sequence. To enhance the immobilization of capture miRNA-137, gold nanostar (GNS) was conjugated with capture miRNA and immobilized on the GO-modified surface through an amine linker. This immobilization process enhanced the hybridization of the target and reaches the detection limit at 10 fM with the sensitivity of 1 fM on the linear curve with a regression coefficient of 0.9038. Further control sequences of miRNA-21 and single and triple base mismatched miRNA-137 did not show a significant response in current changes, indicating the specific miRNA-137 detection for diagnosing AD.
  18. Wong LP, Han L, Li H, Zhao J, Zhao Q, Zimet GD
    Hum Vaccin Immunother, 2019;15(7-8):1533-1540.
    PMID: 31017500 DOI: 10.1080/21645515.2019.1611157
    The introduction of human papillomavirus (HPV) vaccination in China aims to prevent HPV infection in all women. The issues that China might face include high cost of vaccines made in other countries, shortage in HPV vaccine supply, negative events attributed to vaccination (whether justified or not) that jeopardizes the general public's confidence in the HPV vaccine, cultural and literacy barriers, and sensitivity to receiving a vaccine for a sexually transmitted disease. Ensuring the effective delivery of the HPV vaccine in China, a country with vast economic, geographical, and cultural complexities, will require a commitment of significant resources. In light of the high price of imported vaccines, the availability of locally manufactured HPV vaccines would greatly facilitate the national HPV vaccination program. New evidence supporting the efficacy of a two-dose regime in younger adolescents would also be advantageous in terms of affordability and logistical simplicity of vaccine administration. Furthermore, it would potentially enhance the compliance and uptake, especially for hard to reach women in remote regions.
  19. Wang Y, Zhao Y, Xu L, Wang W, Doherty L, Tang C, et al.
    Water Sci Technol, 2017 Jul;76(2):471-477.
    PMID: 28726712 DOI: 10.2166/wst.2017.190
    In the last 10 years, the microbial fuel cell (MFC) has been extensively studied worldwide to extract energy from wastewater via electricity generation. More recently, a merged technique of embedding MFC into a constructed wetland (CW) has been developed and appears to be increasingly investigated. The driving force to integrate these two technologies lies in the fact that CWs naturally possess a redox gradient (depending on flow direction and wetland depth), which is required by MFCs as anaerobic anode and aerobic cathode chambers. No doubt, the integration of MFC with a CW will upgrade the CW to allow it to be used for wastewater treatment and, simultaneously, electricity generation, making CWs more sustainable and environmentally friendly. Currently, published work shows that India, China, Ireland, Spain, Germany and Malaysia are involved in the development of this technology although it is in its infant stage and many technical issues are faced on system configuration, operation and maximisation of electricity production. This paper aims to provide an updated review and analysis of the CW-MFC development. Focuses are placed on the experience gained so far from different researchers in the literature and further research directions and proposals are discussed in great detail.
  20. Shavandi A, Hu Z, Teh S, Zhao J, Carne A, Bekhit A, et al.
    Food Chem, 2017 Jul 15;227:194-201.
    PMID: 28274422 DOI: 10.1016/j.foodchem.2017.01.099
    Squid pens were subjected to alkali hydrolysis to extract chitin and chitosan. Proteins present in the alkaline extraction wastewater were recovered at pH 3, 4, 5 and 6, and were subjected to hydrolysis by trypsin, pepsin and a bacterial protease called HT for 1, 2, 4 and 24h. Hydrolysis of the extracted proteins with either trypsin or HT generated more antioxidant activity than hydrolysis with pepsin. Higher ACE-inhibitory activity was generated in the trypsin and pepsin hydrolysates than in the HT hydrolysate. Squid pen protein recovered from chitosan processing waste alkaline solution can be a potential source of bioactive peptides for addition to foods. The antioxidant and ACE-inhibitory activities of the extracted proteins were initially low and increased upon incubation with the proteases. Pepsin generated significantly lower (P<0.05) antioxidant activities compared to trypsin and HT, while trypsin and pepsin hydrolysates exhibited higher ACE-inhibitory activity than HT (P<0.05).
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