Displaying publications 1 - 20 of 985 in total

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  1. Khovidhungif P
    Family Practitioner, 1977;2:100-100.
    Matched MeSH terms: Thailand
  2. Kantito S, Saokaew S, Yamwong S, Vathesatogkit P, Katekao W, Sritara P, et al.
    J Thromb Thrombolysis, 2018 Feb;45(2):281-290.
    PMID: 29181693 DOI: 10.1007/s11239-017-1588-8
    Patient Self-testing (PST) could be an option for present anticoagulation therapy monitoring, but current evidence on its cost-effectiveness is limited. This study aims to estimate the cost-effectiveness of PST to other different care approaches for anticoagulation therapy in Thailand, a low-to-middle income country (LMIC). A Markov model was used to compare lifetime costs and quality-adjusted life years (QALYs) accrued to patients receiving warfarin through PST or either anticoagulation clinic (AC) or usual care (UC). The model was populated with relevant information from literature, network meta-analysis, and database analyses. Incremental cost-effectiveness ratios (ICERs) were presented as the year 2015 values. A base-case analysis was performed for patients at age 45-year-old. Sensitivity analyses including one-way and probabilistic sensitivity analyses (PSA) were constructed to determine the robustness of the findings. From societal perspective, PST increased QALY by 0.87 and costs by 112,461 THB compared with UC. Compared with AC, PST increased QALY by 0.161 and costs by 21,019 THB. The ICER with PST was 128,697 (3625 USD) and 130,493 THB (3676 USD) per QALY gained compared with UC and AC, respectively. The probability of PST being cost-effective is 74.1% and 51.9%, compared to UC and AC, respectively, in Thai context. Results were sensitive to the efficacy of PST, age and frequency of hospital visit or self-testing. This analysis suggested that PST is highly cost-effective compared with usual care and less cost-effective against anticoagulation clinic. Patient self-testing strategy appears to be economically valuable to include into healthcare system within the LMIC context.
    Matched MeSH terms: Thailand
  3. Cheong WH, Omar AH, Mahadevan S
    Med J Malaya, 1968 Mar;22(3):243.
    PMID: 4234378
    Matched MeSH terms: Thailand
  4. Tawonsawatruk T, Mulpruek P, Hamilton D, Wajanavisit W, Tan S
    Malays Orthop J, 2014 Mar;8(1):37-40.
    PMID: 25347522 DOI: 10.5704/MOJ.1403.016
    It has been reported that oestrogen receptor alpha (ER-α) polymorphisms are associated with knee osteoarthritis (OA). In this study, we assessed whether there was any association between the codon 594 (G>A) polymorphism in ER-α and radiographic features of OA or patient function. Radiographs, WOMAC score and patient reported time of symptom onset were assessed in 194 patients presenting for total knee replacement at Ramathibodi hospital over a one year period. ESR-1 genotyping was assessed. There were 107 (55.15%) patients with common homozygote (GG), 78 (40.20%) patients with heterozygote (GA) and nine (4.65%) patients with rare homozygote (AA). There was poor correlation (r = <0.2) between group difference in the radiographic parameters, time of onset of symptom , or in WOMAC scores. This polymorphism is not associated with the clinical features of knee osteoarthritis. The role of this polymorphism is unlikely then to be used as a biological marker predicting the progression of knee OA.
    Matched MeSH terms: Thailand
  5. Toyokawa H
    Hokenfu Zasshi, 1974 May;30(5):355-9.
    PMID: 4496068
    Matched MeSH terms: Thailand
  6. Saingam D, Singh D, Geater AF, Assanangkornchai S, Jitpiboon W, Latkin C
    Subst Use Misuse, 2023;58(10):1212-1225.
    PMID: 37270449 DOI: 10.1080/10826084.2023.2215301
    BACKGROUND: Mitragyna speciosa or Kratom has been used in Thailand traditionally for its medicinal value. Despite case reports of kratom consumption causing adverse effects, research on its long-term health impact is limited. This study examines the long-term health impact of kratom use among people in Southern Thailand.

    METHODS: Three community-based surveys were conducted from 2011 to 2015. In the first and second surveys (2011 and 2012) a total of 1,118 male respondents comprising 355 regular kratom users, 171 occasional kratom users, 66 ex-users, and 592 non-users aged 25 or above, were recruited from 40 villages. All respondents were followed up in this study. However, not all respondents were successfully followed up throughout the entire set of studies.

    RESULTS: Common health complaints were no more common among kratom users than ex- and non-users, but more regular than occasional users claimed kratom to be addictive. Those with high kratom dependence scores were more likely to experience intense withdrawal symptoms, which developed 1-12 h after the last kratom intake. Over half (57.9%) of regular users had experienced intoxication effects compared to only 29.3% of occasional users. Kratom users were less likely to have a history of chronic diseases such as diabetes, hypertension, dyslipidemia than ex- and non-users.

    CONCLUSION: Regular long-term chewing of fresh kratom leaves was not related to an increase in common health complaints, but may pose a drug dependence risk. Severe kratom dependents were more likely to suffer from intense withdrawal symptoms. Medical records revealed no death due to traditional kratom use, but the high prevalence of tobacco or/and hand rolled cigarette smoking among kratom users should be of concern.

    Matched MeSH terms: Thailand/epidemiology
  7. Tapaopong P, Chainarin S, Mala A, Rannarong A, Kangkasikorn N, Kusolsuk T, et al.
    Malar J, 2024 Nov 13;23(1):342.
    PMID: 39538241 DOI: 10.1186/s12936-024-05162-z
    BACKGROUND: Recent reports from Thailand reveal a substantial surge in Plasmodium knowlesi cases over the past decades, with a more than eightfold increase in incidence by 2023 compared to 2018. This study investigates temporal changes in genetic polymorphism associated with the escalating transmission of P. knowlesi malaria in Thailand over time using the prominent vaccine candidate, pkmsp1 as a marker.

    METHODS: Twenty-five P. knowlesi samples collected in 2018-2023 were sequenced for the 42-kDa region of pkmsp1 and compared with 24 retrieved sequences in 2000-2009, focusing on nucleotide diversity, natural selection, recombination rate, and population differentiation.

    RESULTS: Seven unique haplotypes were identified in recent samples, compared to 15 in earlier samples. Nucleotide and haplotype diversity were lower in recent samples (π = 0.016, Hd = 0.817) than in earlier samples (π = 0.018, Hd = 0.942). Significantly higher synonymous substitution rates were observed in both sample sets (dS-dN = 2.77 and 2.43, p Thailand or Malaysia. Conversely, the relatively lower Fst value between southern Thailand and Malaysia suggests a closer genetic relationship, possibly reflecting historical gene flow.

    CONCLUSION: This study highlights a decline in genetic diversity and evidence of purifying selection associated with the recently increased incidence of P. knowlesi malaria in Thailand. The minor genetic differentiation between P. knowlesi populations from southern Thailand and Malaysia suggests a shared recent ancestry of these parasites and underscores the need for coordinated efforts between the two countries for the elimination of P. knowlesi.

    Matched MeSH terms: Thailand/epidemiology
  8. Solomon N
    Reprod Health Matters, 2005 May;13(25):174-81.
    PMID: 16035611
    Matched MeSH terms: Thailand
  9. Thanaviratananich S, Cho SH, Ghoshal AG, Abdul Muttalif AR, Lin HC, Pothirat C, et al.
    Medicine (Baltimore), 2016 Jul;95(28):e4090.
    PMID: 27755477
    Asia-Pacific Burden of Respiratory Diseases (APBORD) was a cross-sectional, observational study examining the burden of respiratory disease in adults across 6 Asia-Pacific countries.This article reports symptoms, healthcare resource utilization (HCRU), work impairment and cost burden associated with allergic rhinitis (AR), asthma, chronic obstructive pulmonary disease (COPD), and rhinosinusitis in Thailand.Consecutive participants aged ≥18 years with a primary diagnosis of AR, asthma, COPD, or rhinosinusitis were enrolled at 4 hospitals in Thailand during October 2012 and October 2013. Participants completed a survey detailing respiratory symptoms, HCRU, work productivity, and activity impairment. Locally sourced unit costs were used in the calculation of total costs.The study enrolled 1000 patients. The most frequent primary diagnosis was AR (44.2%), followed by rhinosinusitis (24.1%), asthma (23.7%), and COPD (8.0%). Overall, 316 (31.6%) of patients were diagnosed with some combination of the 4 diseases. Blocked nose or congestion (17%) and cough or coughing up phlegm (16%) were the main reasons for the current medical visit. The mean annual cost for patients with a respiratory disease was US$1495 (SD 3133) per patient. Costs associated with work productivity loss were the principal contributor for AR and rhinosinusitis patients while medication costs were the highest contributor for asthma and COPD patients.The study findings highlight the burden associated with 4 prevalent respiratory diseases in Thailand. Thorough investigation of concomitant conditions and improved disease management may help to reduce the burden of these respiratory diseases.
    Matched MeSH terms: Thailand
  10. Saito Y, Vasuvat C, Harinasuta C
    Med J Malaya, 1968 Mar;22(3):247.
    PMID: 4234385
    Matched MeSH terms: Thailand
  11. Bucy PC
    Surg Neurol, 1975 Sep;4(3):343-4.
    PMID: 1179253
    Matched MeSH terms: Thailand
  12. Natita Wangsoh, Wiboonsak Watthayu, Dusadee Sukawat
    Sains Malaysiana, 2017;46:2541-2547.
    A hybrid climate model (HCM) is a novel proposed model based on the combination of self-organizing map (SOM) and analog method (AM). The main purpose was to improve the accuracy in rainfall forecasting using HCM. In combination process of HCM, SOM algorithm classifies high dimensional input data to low dimensional of several disjointed clusters in which similar input is grouped. AM searches the future day that has similar property with the day in the past. Consequently, the analog day is mapped to each cluster of SOM to investigate rainfall. In this study, the input data, geopotential height at 850 hPa from the Climate Forecast System Reanalysis (CFSR) are training set data and also the complete rainfall data at 30-meteorological stations from Thai meteorological department (TMD) are observed. To improve capability of rainfall forecasting, three different measures were evaluated. The experimental results showed that the performance of HCM is better than the traditional AM. It is illustrated that the HCM can forecast rainfall proficiently.
    Matched MeSH terms: Thailand
  13. Theodor O
    Indian J Med Res, 1938;26:261-9.
    Matched MeSH terms: Thailand
  14. Ginal P, Schmitz LM, Rödder D
    Zootaxa, 2022 Dec 05;5214(4):595-599.
    PMID: 37044888 DOI: 10.11646/zootaxa.5214.4.7
    The mossy frogs of the genus Theloderma Tschudi comprise 28 described taxa (Sivongxay et al. 2016; Frost 2022), which are distributed from north-eastern India and Myanmar to southern China, across the peninsula of Indochina and Malaysia, to Indonesia (Poyarkov et al. 2015; Frost 2022). Theloderma albopunctatum is a small-sized taxon that is assigned to the T.-asperum species complex (Poyarkov et al. 2015, 2018; Sivongxay et al. 2016; Dever 2018). For long time, it has been believed to be a synonym of T. asperum. However, genetic analyses revealed that both taxa show significant differences. Currently, populations south of the Isthmus of Kra (southern Thailand, Malayan peninsular) are assigned to T. asperum, while populations north of it (southern China, northern and central Vietnam, adjacent Laos, south-eastern Cambodia) are assigned to T. albopunctatum. In addition, this species complex might contain further cryptic species (cf. Nguyen et al. 2015; Poyarkov et al. 2015) and according to Chunskul et al. (2021) four genetic groups do exist: group A comprises T. albopunctatum from southern and central Vietnam, Laos, central and north-eastern Thailand; group B is composed of populations from northern Vietnam and China; group C ranges from north-western Vietnam to northern Thailand and Myanmar; and group D is distributed in northern Vietnam (Thanh Hoa).
    Matched MeSH terms: Thailand
  15. Donworth P, Wesener T
    Zootaxa, 2024 Mar 08;5419(4):545-562.
    PMID: 38480309 DOI: 10.11646/zootaxa.5419.4.4
    Thailand hosts a very rich but underexplored giant pill-millipede (Sphaerotheriida) fauna, with 11 of its 13 species described in the last three years. Currently, all known Thai giant pill-millipedes belong to the genera Zephronia Gray, 1832 (nine species) and Sphaerobelum Verhoeff, 1924 (four species). Here we describe the first two species of the genus Prionobelum Verhoeff, 1924 (previously restricted to Vietnam and China), Prionobelum inthanonense n. sp. and P. naevium n. sp. from Thailand. The species occur at Thailands highest mountain (2500 m) Doi Inthanon and the lowland rainforests at Bang Lang National Park touching the border with Malaysia. Both species are described integratively, utilizing light microscopy, scanning electron microscopy as well as DNA barcoding. Both new species of Prionobelum differ from other Zephroniidae species, as well as from one another, by more than 20% p-distance in the COI barcoding gene suggesting that potential closer related species are still awaiting discovery.
    Matched MeSH terms: Thailand
  16. Terada M, Nakamura K, Matsuda T, Okuma HS, Sudo K, Yusof A, et al.
    Jpn J Clin Oncol, 2023 Jun 29;53(7):619-628.
    PMID: 37099440 DOI: 10.1093/jjco/hyad033
    This report summarizes the presentations and discussions in the first Asian Clinical Trials Network for Cancers (ATLAS) international symposium that was held on 24 April 2022, in Bangkok, Thailand, and hosted by the National Cancer Center Hospital (NCCH), co-hosted by the Pharmaceuticals and Medical Devices Agency (PMDA), Clinical Research Malaysia (CRM) and the Thai Society of Clinical Oncology (TSCO), and supported by Embassy of Japan in Thailand. Since 2020, the NCCH has conducted the ATLAS project to enhance research environments and infrastructures to facilitate international clinical research and cancer genomic medicine in the Asian region. The purpose of the symposium was to discuss what we can achieve under the ATLAS project, to share the latest topics and common issues in cancer research and to facilitate mutual understanding. Invitees included stakeholders from academic institutions, mainly at ATLAS collaborative sites, as well as Asian regulatory authorities. The invited speakers discussed ongoing collaborative research, regulatory perspectives to improve new drug access in Asia, the status of phase I trials in Asia, the introduction of research activities at the National Cancer Center (NCC) and the implementation of genomic medicine. As the next steps after this symposium, the ATLAS project will foster increased cooperation between investigators, regulatory authorities and other stakeholders relevant to cancer research, and establish a sustainable pan-Asian cancer research group to increase the number of clinical trials and deliver novel drugs to patients with cancer in Asia.
    Matched MeSH terms: Thailand
  17. Wongwaiyut P, Karapan S, Saekong P, Francis CM, Guillén-Servent A, Senawi J, et al.
    Zootaxa, 2023 May 03;5277(3):401-442.
    PMID: 37518310 DOI: 10.11646/zootaxa.5277.3.1
    A new species of small Hipposideros in the bicolor group is described based on specimens from Thailand and Malaysia. It can be distinguished from other small Hipposideros in Southeast Asia by a combination of external, craniodental, and bacular morphology, as well as echolocation call frequency. The new species has a distinct rounded swelling on the internarial septum of the noseleaf, with a forearm length of 35.3-42.6 mm, greatest skull length of 15.94-17.90 mm, and a call frequency of maximum energy of 132.3-144.0 kHz. Although clearly different in morphology, the new species forms a sister clade with H. kunzi and H. bicolor in the phylogenetic trees based on mitochondrial DNA. In addition, this study reports echolocation and genetic data, with a confirmed record of H. einnaythu from Thailand for the first time. The new species most closely resembles H. einnaythu. However, it differs in the details of the noseleaf and craniodental morphology, and it has a genetic distance of 9.6% and 10.4% based on mitochondrial COI and ND2, respectively. It is currently documented from five localities: two in peninsular Thailand, at Hala Forest in Yala Province, and Phru To Daeng Swamp Forest in Narathiwat Province, one from peninsular Malaysia at Krau Wildlife Reserve in Pahang, and another two in Sabah, Malaysian Borneo at Gunung Kinabalu, and near Madai Caves. However, it is likely that many previous records of "H. cineraceus" from Borneo refer to this species. Most records of the species are from lowland evergreen rainforest, though one record from Sabah was at 1800m. The roosting sites for this new species are currently unknown. Future research with a combination of data such as genetics, echolocation and morphology would be necessary to further determine the species geographic distribution in Southeast Asia.
    Matched MeSH terms: Thailand
  18. Tan ZW, Lheknim V, Ng PKL
    Zootaxa, 2023 Oct 30;5360(4):531-544.
    PMID: 38220598 DOI: 10.11646/zootaxa.5360.4.4
    A new species of freshwater crab is described from southern Thailand, near the border with Peninsular Malaysia. Species of Stoliczia are characterised by their relatively flat carapace, a third maxilliped exopod that possesses no or a very short flagellum, and a conical male gonopod terminal segment that lacks or only has a very low dorsal fold. Stoliczia setoiyenica, new species, most closely resembles S. perlensis and S. kedahensis from northern Peninsula Malaysia but can be easily distinguished from congeners by differences in carapace and male gonopod morphology. Comparisons to the two known Thai Stoliczia species, S. panhai and S. ekavibhathai, are also provided for completeness.
    Matched MeSH terms: Thailand
  19. Mongkonkansai J, Veerasakul S, Tamrin SBM, Madardam U
    Int J Environ Res Public Health, 2022 Aug 24;19(17).
    PMID: 36078252 DOI: 10.3390/ijerph191710530
    School-age children increasingly use smartphones to conduct their learning activities; increasing reports of disorders related to smartphone use exist, including visual-related symptoms, stress, and musculoskeletal pain. This study aimed to examine risk factors for musculoskeletal pain among primary school students using smartphones. A cross-sectional study was conducted with 233 school-aged children in Nakhon Si Thammarat, Thailand. Data collection used a questionnaire for musculoskeletal symptoms using the Nordic Musculoskeletal Questionnaire with ISO 11,226:2000. Through Chi-square, t-test, and logistic regression analysis, factors independently associated with musculoskeletal pain were determined. An important factor in the development of musculoskeletal pain was the prolonged use of smartphones for longer than 60 min, particularly among children aged 6-9 years old. In regards to musculoskeletal pain, almost 53% of the students used their smartphones while lying down. Posing in a prone position while using a smartphone was 7.37 times more dangerous than sitting. The laying position tilts numerous organs at varying angles, especially the upper arm. The risk of musculoskeletal complaints must be reduced by educating parents, children, and the relevant government organizations about safe smartphone usage. The mentioned factors may be used to anticipate the onset of musculoskeletal pain caused by smartphone use in young children.
    Matched MeSH terms: Thailand/epidemiology
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