MyMedR

Fulltext Vaginal hysterectomy for the large uterus

Teoh TGK

Med J Malaysia, 2001 Dec;56(4):460-2.

PMID: 12014766

Vaginal hysterectomy for the large uterus is seldom performed in Malaysia. The traditional operation is abdominal hysterectomy. This is a personal series of vaginal hysterectomies for enlarged uterus of more than 12 weeks size (>280g) carried out in a private hospital between 1/1/97 to 30/9/2000. A total of 40 cases were done with the weights of the uterus ranging from 290g to 790g. The mean weight of the uterus was 434g. The average operating time was 92.1 min. The complications were minimal with 2 cases of blood transfusion for intra-operative hemorrhage, 1 case of fever and 1 case of bladder perforation. This series demonstrates feasibility and safety of the operation. The excellent recovery due to the absence of an abdominal scar should be a strong incentive for specialists to learn the skill.

Matched MeSH terms: Uterine Diseases/pathology; Uterine Diseases/surgery*

Acute inversion of the uterus: a report of 2 cases and reappraisal of the method of management

Ping WW, Sinnathuray TA

Med J Malaya, 1970 Sep;25(1):54-7.

PMID: 4249498

Matched MeSH terms: Uterine Diseases/complications; Uterine Diseases/therapy*

Fulltext Outcome of vaginal hysterectomy for the undescended and enlarged uterus--a preliminary report

Teoh TGK

Med J Malaysia, 1996 Dec;51(4):415-9.

PMID: 10968027

This is a retrospective observational study of outcome of 11 cases of vaginal hysterectomy for undescended and enlarged uterus carried in University Hospital, Kuala Lumpur. The cases included relative contraindications such as 14 weeks size fibroids, severe obesity, previous Caesarean section and nulliparity. All the eight patients agreeable for prophylactic bilateral salpingoophorectomy had their ovaries removed. Operative time ranged from 1 hr 20 min to 2 hr 15 min. All patients were sent home within 48 hours of the operation. The excellent outcome of our initial experience highlights the known advantages of vaginal hysterectomy for undescended and enlarged uterus.

Matched MeSH terms: Uterine Diseases/surgery*

Fulltext Normograms of Ovarian Volume, Uterine Size and Endometrial Thickness in Urban Midlife Malaysia Women

Adeeb, N., Nur Azurah, A.G., Ong, F.B., Seri, S.S., Shamsuddin, K., Noor Aini, M.Y.

Medicine & Health, 2007;2(1):66-79.

MyJurnal

Cancers of the ovary and corpus uteri afflict 5% and 3.6% Malaysian women respectively. Ovarian cancer (OC) remained the deadliest gynaecological malignancy in perimenopausal women mainly due to the lack of symptoms until the disease had spread. Ultrasonography could provide a preliminary screening allowing the clinician to tailor subsequent management and counselling for these women. To support the basis for selective screening, a study on 517 urban disease free women aged 45 years and above, uterus-intact, non-users of HRT was undertaken. This study presented normograms of ovary, uterus and endometrium derived from entry ultrasound assessment. The sample comprised of 58.0% premenopaused and 42.0% postmenopaused women with an average age of 51.27±5.35 years old. Over two thirds were Chinese followed by Malays and Indians. The findings indicated that the average uterine size and endometrial thickness (ET) was 7.21±1.67x4.36±1.30cm and 6.36±3.73mm respectively. Premenopausal women had larger uterus compared to those postmenopaused (p

Matched MeSH terms: Uterine Diseases

Acute puerperal inversion of the uterus--an obstetric emergency

Rachagan SP, Sivanesaratnam V, Kok KP, Raman S

Aust N Z J Obstet Gynaecol, 1988 Feb;28(1):29-32.

PMID: 3214380

Over a 17-year period, 15 patients with acute puerperal inversion of the uterus were managed at the University Hospital, Kuala Lumpur, an incidence of 1 in 4,836 deliveries. Injudicious traction on the umbilical cord before the uterus was well contracted, was probably the most important causative factor. Haemorrhage was more severe when removal of the placenta was done prior to correction of the inversion. Either the hydrostatic method or manual replacement were used but more often a combination of both techniques was found necessary. With careful management of the third stage of labour, this complication can be avoided.

Matched MeSH terms: Uterine Diseases/therapy*

Fulltext MicroRNAs in Endometriosis: Insights into Inflammation and Progesterone Resistance

Hon JX, Wahab NA, Karim AKA, Mokhtar NM, Mokhtar MH

Int J Mol Sci, 2023 Oct 09;24(19).

PMID: 37834449 DOI: 10.3390/ijms241915001

Endometriosis, a non-malignant gynecological disorder influenced by estrogen, involves the growth of endometrial tissue outside the uterus. Its development includes processes such as inflammation, progesterone resistance, angiogenesis, and cell proliferation. Epigenetic factors, particularly the dysregulation of microRNAs (miRNAs), have emerged as key factors in these mechanisms in endometriosis. This review aims to unveil the intricate molecular processes that control inflammation, progesterone resistance, and miRNA functions in endometriosis. In addition, it provides a comprehensive overview of the current understanding regarding the involvement of miRNAs in the inflammatory aspects of this condition. This synthesis encompasses research investigating the molecular underpinnings of inflammation, along with the biogenesis and roles of miRNAs in endometriosis. Furthermore, it examines human studies and functional analyses to establish the intricate connection between miRNAs, inflammation, and progesterone resistance in the context of endometriosis. The results highlight the significant impact of dysregulated miRNAs on the inflammatory pathways and hormonal imbalances characteristic of endometriosis. Consequently, miRNAs hold promise as potential non-invasive biomarkers and targeted therapeutic agents aimed at addressing inflammation and enhancing the response to progesterone treatment in individuals with endometriosis.

Matched MeSH terms: Uterine Diseases*

Fulltext Degenerated uterine fibroid mimicking hydrometra: fallacy in CT

Tok Ch, Bux S, Mohamed S, Lim B

Biomed Imaging Interv J, 2006 Oct;2(4):e42.

PMID: 21614328 MyJurnal DOI: 10.2349/biij.2.4.e42

Fibroids are the commonest uterine neoplasms, occurring in 20% - 30% of women of reproductive age. In women who have pelvic masses of unknown cause, unusual manifestations of fibroids such as necrosis or degeneration may simulate a carcinoma or hydrometra resulting in problems with image interpretation. We report a case of an unsuspected large degenerated uterine fibroid in a lady mistakenly diagnosed as hydrometra on computed tomography scanning.

Matched MeSH terms: Uterine Diseases

Uterine horn torsion in a pregnant cat

Thilagar S, Yew YC, Dhaliwal GK, Toh I, Tong LL

Vet Rec, 2005 Oct 29;157(18):558-60.

PMID: 16258139

Matched MeSH terms: Uterine Diseases/pathology; Uterine Diseases/surgery; Uterine Diseases/veterinary*

Utero-cutaneous fistula after caesarean section secondary to red degeneration of intramural fibroid

Lim PS, Shafiee MN, Ahmad S, Hashim Omar M

Sex Reprod Healthc, 2012 Jun;3(2):95-6.

PMID: 22578758 DOI: 10.1016/j.srhc.2012.03.002

A 33 year-old woman had an emergency caesarean section for retained second twin which was complicated by utero-cutaneous fistula due to red degeneration of intramural fibroid. The utero-cutaneous communication was demonstrated by an examination under anaesthesia using dye test. She then underwent excision of the fistula tract and myomectomy. She recovered well following the surgery. This is the first case of utero-cutaneous fistula where the communication is between the endometrial cavity and skin lesion via a necrotic intramural fibroid following caesarean section. Fistulogram might fail to demonstrate the communication. In highly suspected case, other modalities of investigations could be utilised.

Matched MeSH terms: Uterine Diseases/etiology*; Uterine Diseases/pathology*

Case report: torsion of a gravid horn of a didelphic uterus

Achanna S, Monga D, Hassan MS

J Obstet Gynaecol Res, 1996 Apr;22(2):107-9.

PMID: 8697337

Acute abdominal pain during pregnancy presents a dilemma as signs and symptoms are often modified. Abdominal massage by traditional birth attendants (TBAs') during early labour is a common practice in the rural population, as it is perceived to give a soothening effect to the labouring mother. Many instances of abruptio placentae were reported in the past by this procedure, and in this case, the clinical picture presented as an abruptio placenta. Malpresentation and failure to progress were the indications for caesarean section despite the fetal demise. Severe post partum haemorrhage and failure to contract despite massive oxytocics resulted in the hysterectomy of the gravid horn, leaving the other horn intact.

Matched MeSH terms: Uterine Diseases/diagnosis*; Uterine Diseases/physiopathology; Uterine Diseases/surgery

Endometrial amoebiasis

Othman NH, Ismail AN

Eur J Obstet Gynecol Reprod Biol, 1993 Dec 15;52(2):135-7.

PMID: 8157142

A case of endometrial infection by Entamoeba histolytica is described in an elderly lady who presented with profuse vaginal discharge and was clinically misdiagnosed as endometrial carcinoma.

Matched MeSH terms: Uterine Diseases/diagnosis*

A Challenge in Diagnosis and Management: Uterine Torsion in Childhood

Thever Ramasamy V, Sivapatham L, Grover SR, Shanmugam SS, Ganesalingam M

J Pediatr Adolesc Gynecol, 2021 Feb;34(1):61-64.

PMID: 33010465 DOI: 10.1016/j.jpag.2020.09.003

BACKGROUND: Uterine torsion is a rare event, which mostly reported in females with a gravid uterus and is exceptionally rare in children.

CASE: A 9-year-old girl presented with 3 days of intermittent lower abdominal pain. Ultrasound revealed an ovarian mass, but laparotomy revealed an ischemic enlarged ovary and uterus rotated 180°. No reperfusion occurred after 60 minutes. A subtotal hysterectomy and right salpingoophorectomy were thus performed.

CONCLUSION: Uterine and adnexal torsion presents with symptoms similar to those of adnexal torsion. Delays in diagnosis and referral continue to be an issue, resulting in suboptimal outcomes. Uterine torsion, although exceedingly rare in childhood, appears to occur only in the setting of ovarian masses, which provide the impetus for the rotational force to the elongated cervix of the prepubertal uterus.

Matched MeSH terms: Uterine Diseases/surgery*

Concordance between hysteroscopic impression and endometrial histopathological diagnosis

Gan DE, Jawan RA, Moy FM

Prev Med, 2013;57 Suppl:S21-3.

PMID: 23313791 DOI: 10.1016/j.ypmed.2012.12.026

The aim of this study was to evaluate the accuracy of hysteroscopic impression for diagnosing benign and malignant endometrial pathology.

Matched MeSH terms: Uterine Diseases/diagnosis*; Uterine Diseases/pathology

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