Browse publications by year: 2015

  1. Nurrul Assyikeen Md. Jaffary, Wo, Yii Mei, Abdul Kadir Ishak, Noor Fadzilah Yusof, Kamarozaman Ishak, Maziah Mahmud, et al.
    MyJurnal
    On March 11, 2011, a serious accident occurred in Daiichi nuclear reactor plant, Fukushima,
    Japan which caused radioactive materials been released into the atmosphere in the form of
    aerosols and dust particles. Sea water around the plant was also found contaminated with high
    radioactivity readings. These radioactive materials could be transported by the winds and ocean
    current across international borders and cannot be controlled by human. Thus, a continuous
    monitoring activity of radionuclide content in the air and sea water needs to be conducted by the
    authorities. In addition to radioactivity monitoring, Malaysia should also control the entry of
    contaminated food in order to prevent radionuclide ingestion by human. The radionuclide 131I,
    134Cs and 137Cs were used as a measure of pollution levels and counted with gamma spectrometry
    using standard analysis method suggested by AOAC International. In this paper, details description
    of the role of Radiochemical and Environment Group, Nuclear Malaysia who’s responsible in
    analyzing the radioactivity in the food samples due to Fukushima Daiichi, Japan accident was
    included. The radioactivity limit adopted and analysis results from this monitoring were discussed
    MeSH terms: Aerosols; Atmosphere; Dust; Humans; Japan; Malaysia; Nuclear Reactors; Oceans and Seas; Radioactivity; Radiochemistry; Radioisotopes; Seawater; Spectrometry, Gamma; Wind; Fukushima Nuclear Accident
  2. Ros Anita Ahmad Ramli, Ahmad Zainuri Mohd Dzomir, Zainon Othman, Wan Saffiey Wan Abdullah, Muhamad Samudi Yasir
    MyJurnal
    The exposure of food to ionizing radiation is being progressively used in many countries to
    inactivate food pathogens, to eradicate pests and to extend shelf-life of food. To ensure free
    consumer choice, irradiated food will be labeled. The availability of a reliable method to detect
    irradiated food is important to enforce legal controls on labeling requirements, ensure proper
    distribution and increase consumer confidence. This paper reports on the preliminary application
    of photostimulated luminescence technique (PSL) as a potential method to detect irradiated food
    and perhaps be used for monitoring irradiated food on sale locally in the near future. Thus this
    study will be beneficial and relevant for application of food irradiation towards improving food
    safety and security in Malaysia.
    MeSH terms: Commerce; Food; Food Irradiation; Luminescent Measurements; Malaysia; Product Labeling; Radiation, Ionizing; Luminescence
  3. Shakinah Salleh, Zaiton Ahmad, Affrida Abu Hassan, Yahya Awang, Yutaka Oono
    MyJurnal
    Chrysanthemum morifolium is an important temperate cut flower for Malaysian floriculture
    industry and the lack of new local owned varieties led to this mutation breeding research. The
    objective of this study was to compare the effectiveness of ion beam irradiation in generating
    mutations on ray florets and nodal explants of Chrysanthemum morifolium cv. ‘Reagan Red’. Ion
    beams has become an efficient physical mutagen for mutation breeding. The ray florets and nodal
    explants were irradiated with ion beams at doses 0, 0.5, 1.0, 2.0, 3.0, 5.0, 8.0, 10, 15, 20 and 30 Gy.
    The 50% of in vitro shoot regeneration (RD50) for ray florets explants was 2.0 Gy and for nodal
    explants was 4.0 Gy. Thus, relative biological effectiveness (RBE) for ray florets was found 2.0
    times higher than the nodal explants. The regenerated plantlets were planted in the greenhouse at
    MARDI, Cameron Highlands for morphological screening. Overall performance of survival
    plantlets derived from in vitro nodal and ray floret explants was recorded. The characters studied
    include plant morphology and flowering characteristic. The ray florets explants were found to be
    more sensitive to ion beam irradiation and generated more mutations as compared to nodal
    explants.
    MeSH terms: Breeding; Mutagens; Mutation; Regeneration; Relative Biological Effectiveness; Research; Chrysanthemum; Flowers
  4. Khairuddin Mohamad Kontol, Ismail Sulaiman, Faizal Azrin Abdul Razalim
    MyJurnal
    Sludge and scales produced during oil and gas production contain enhanced naturally occurring
    radioactive material (NORM). Sludge and scales are under the jurisdiction of Department of
    Environment (DOE) and also Atomic Energy Licensing Board (AELB). AELB has issued a
    guideline regarding the disposal of sludge and scales as in its guideline (LEM/TEK/30 SEM.2,
    1996). In this guideline, Radiological Impact Assessment (RIA) should be carried out on all
    proposed disposals and has to demonstrate that no member of public will be exposed to more than
    1 mSv/y. This paper presented RIA analysis using RESRAD computer code for the disposal of
    treated sludge. RESRAD (RESidual RADioactive) developed by Argonne National Laboratory is to
    estimate radiation doses and risks from residual radioactive materials. The dose received by the
    member of public is found to be well below the stipulated limit.
    MeSH terms: Nuclear Energy; Paper; Radioactivity; Risk; Sewage
  5. Ismail Mustapha, Samihah Mustaffh, Md Fakarudin Ab Rahman, Roslan Yahya, Lahasen @ Norman Shah Dahin, Nor Pa’iza Mohd Hasan, et al.
    MyJurnal
    Non-destructive and real time method becomes a well-liked method to researchers in the oil palm
    industry since 2000. This method has the ability to detect oil content in order to increase the
    production of oil palm for better profit. Hence, this research investigates the potential of neutron
    source to estimate oil content in palm oil fruit since oil palm contains hydrogen with chemical
    formula C55H96O6. For this paper, oil palm loose fruit was being used and divided into three
    groups. These three groups are ripe, under-ripe and bruised fruit. A total of 21 loose fruit for each
    group were collected from a private plantation in Malaysia. Each sample was scanned using
    neutron backscattered technique. The higher neutron count, the more hydrogen content, and the
    more oil content in palm oil fruit. The best correlation result came from the ripe fruits with r2=0.98.
    This research proves that neutron backscattered technique can be used as a non-destructive and
    real time grading system for palm oil.
    MeSH terms: Fruit; Hydrogen; Malaysia; Neutrons; Plant Oils; Research; Research Personnel
  6. Chen I, Jamal S, Pua KC
    Malays Fam Physician, 2015;10(3):32-4.
    PMID: 27570606 MyJurnal
    Primary tuberculosis (TB) of the hard palate is very rare. A 74-year-old man was presented with 6-month history of dysphagia along with an irregular mass in the hard and soft palate. Magnetic resonance imaging (MRI) revealed thickened and increased signal intensity within hard and soft palate. Tissue biopsy showed focal caseating granulomatous-like lesion and the histochemical staining using Ziehl-Neelsen stain for acid-fast bacilli was positive. Positive histochemical studies provided evidences that the hard palate mass was most likely due to TB. Thus, the patient was started on antituberculous therapy.
    MeSH terms: Aged; Biopsy; Deglutition Disorders; Coloring Agents; Humans; Magnetic Resonance Imaging; Male; Palate, Soft; Staining and Labeling; Tuberculosis; Palate, Hard
  7. Awaluddin A, Jali N, Bahari R, Jamil Z, Haron N
    Malays Fam Physician, 2015;10(3):27-31.
    PMID: 27570605 MyJurnal
    Management of bipolar disorder (BD) is challenging due to its multiple and complex facets of presentations as well as various levels of interventions. There is also limitation of treatment accessibility especially at the primary care level. Local evidence-based clinical practice guidelines address the importance of integrated care of BD at various levels. Primary care physicians hold pertinent role in maintaining remission and preventing relapse by providing systematic monitoring of people with BD. Pharmacological treatment in particular mood stabilisers remain the most effective management with psychosocial interventions as adjunct. This paper highlights the role of primary care physicians in the management of BD.
    MeSH terms: Bipolar Disorder; Humans; Primary Health Care; Guideline*; Disease Management; Physicians, Primary Care
  8. Rahman MM, Arif MT, Abd Razak MF, Suhaili MR, Tambi Z, Akoi C, et al.
    Malays Fam Physician, 2015;10(3):19-26.
    PMID: 27570604 MyJurnal
    Introduction: Specific health warning placed on the tobacco product packages is considered as an effective and low-cost method for increasing the knowledge and awareness among the community. Thus, a study was conducted to assess the perception of pictorial health warnings (PHWs) against smoking among the adult rural population of Sarawak.
    Methods: Cross-sectional data were collected from 10 villages in Kota Samarahan and Kuching Division by face to face interview using modified Global Adult Tobacco Survey questionnaire. Nonprobability sampling method was adopted to select the villages. All the households of the selected villages were visited and an adult member was selected randomly from each house irrespective of the sex. After missing value imputation, 1000 data were analysed using statistical software IBM SPSS 20.0 version.
    Results: Analysis showed that 28.8% of the respondents were current smokers, 7.8% were past smokers and the rest were non-smokers. Six items of pictorial health warnings were evaluated with five point Likert’s scales for attractiveness, fearfulness and adequacy of the information. Analysis revealed that the majority of the respondents had perceived awareness on PHWs, but the smokers believed that this was not adequate to make them quit smoking. Only one-fifth (19.7%) of them reported that current pictorial health warnings were sufficient to motivate people to quit smoking.
    Conclusion: Though the PHWs on cigarette packages are appealing, it is not sufficient as a reason to stop smoking. Thus, an approach using an integrated anti-tobacco public health programme should be focused into the specific targeted community
    MeSH terms: Adult; China/ethnology; Cross-Sectional Studies; Female; Humans; Malaysia; Malaysia/ethnology; Male; Motivation; Public Health; Surveys and Questionnaires; Rural Population; Smoking; Software; Tobacco; Tobacco Use Disorder; Tobacco Products
  9. Hong JYH, Jalaludin MY, Mohamad Adam B, Fuziah MZ, Wu LL, Rasat R, et al.
    Malays Fam Physician, 2015;10(3):11-18.
    PMID: 27570603 MyJurnal
    Background: Diabetic ketoacidosis (DKA) is a late presentation of newly diagnosed type 1 diabetes mellitus (DM) in children. The aim of this study was to determine the clinical characteristics of type 1 DM at presentation so that appropriate actions can be taken to promote early diagnosis.
    Methods: This was a retrospective cohort review from a patient registry database. Data on all patients younger than 20 years old diagnosed with type 1 DM who had been registered with the Malaysian Diabetes in Children and Adolescents Registry (DiCARE) from its inception in 2006 until 2009 were analysed.
    Results: The study included 490 children and adolescents, out of which 57.1% were female. The mean (SD) age at diagnosis was 7.5 (3.7) years, which increased from year 2000 to 2009 [6.6 (3.3) years to 9.6 (3.5) years; p = 0.001]. An increasing percentage of DKA at diagnosis was observed from year 2000 (54.5%) to year 2009 (66.7%), which remained high and leveled between 54.5% and 75.0%. DKA was more common in patients with normal weight (p = 0.002) with no significant association with age, gender, ethnicity and status of family history of diabetes mellitus.
    Conclusion: An increasing trend of age at diagnosis of patients with type 1 DM was observed. Besides that, proportion of DKA at diagnosis had remained high over the past decade. This study found that normal weight was associated with status of DKA, thus more detailed investigations are required to determine the risk factors for DKA.
    MeSH terms: Adolescent; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Ethnic Groups; Female; Humans; Malaysia; Registries; Retrospective Studies; Risk Factors; Databases, Factual; Diabetic Ketoacidosis; Early Diagnosis
  10. Yaacob NA, Abdullah SK, Ahmad I, Yahya NA, Draman N, Ismail SB, et al.
    Malays Fam Physician, 2015;10(3):2-10.
    PMID: 27570602 MyJurnal
    Introduction: In Malaysia, the prevalence of menstrual disorders among adolescents and young adults is high. However, most of them are not aware of the signs and symptoms of menstrual
    disorders in terms of medical issue as well as Islamic ruling. Awareness of the menstrual disorder
    symptoms is important so that early and appropriate treatment can be given.

    Objectives: The objective of the study was to compare the knowledge and attitude of premarital
    men and women on menstrual disorders.

    Methods: This was a comparative cross sectional study conducted in Kota Bharu, Kelantan. Self-administered
    questionnaires were given for data collection. The questionnaires consisted of 3 parts
    that required information on the women’s and men’s socio-demographic data, women’s menstrual
    history and information in knowledge and attitude of men and women on menstrual disorders.

    Results: A total of 460 respondents were involved in this study with a response rate of 93.5%. The
    prevalence of good knowledge was higher among women compared to men with 73.2% and 26.8%,
    respectively. There was a significant difference on knowledge and attitude on menstrual disorders
    between premarital men and women.

    Conclusion: Both premarital men and women had low knowledge on menstrual disorder with men
    knowing less than the women.
    MeSH terms: Adolescent; Adult; Cross-Sectional Studies; Female; Humans; Islam; Malaysia; Malaysia/ethnology; Male; Menstruation Disturbances; Surveys and Questionnaires; Prevalence
  11. Asma Hayati Ahmad, Rahimah Zakaria
    MyJurnal
    Stress modulates pain perception, resulting in either stress-induced analgesia or stressinduced
    hyperalgesia, as reported in both animal and human studies. The responses to stress include
    neural, endocrine, and behavioural changes, and built-in coping strategies are in place to address
    stressors. Peculiar to humans are additional factors that modulate pain that are experienced in
    times of stress, notably psychological factors that potentially influence the directionality of pain
    perception.
    MeSH terms: Adaptation, Psychological; Analgesia; Animals; Humans; Hyperalgesia; Pain; Pain Perception; Pain Management
  12. Wan Nor Azlen Wan Mohamad, Normah Che Din, Norlinah Ibrahim
    MyJurnal
    A cross-sectional study was carried out at a medical centre to determine the cognitive profiles
    of 30 Parkinson’s disease patients with age of 69.76 ± 7.39 years. Thirty-seven percent of the patients
    were found to be at risk for dementia. The scores on subscales of working memory and alternating
    verbal fluency were significantly lower in Parkinson’s disease patients who were older than 77 years
    old. The scores on a subtest of working memory on the Parkinson’s Disease Cognitive Rating Scale
    (PDCRS) were significantly lower in Parkinson’s disease patients with a duration of illness of more
    than10 years. Incognitivemeasurement,the subtestsof verbalmemory,delayedfree recallandverbal
    fluency on the PD¬CRS were significantly lower in patients with less than six years of education. The
    patients who had difficulty with sustained attention, working memory and movement had significant
    anxiety and depression symptoms. In conclusion, multiple patterns in cognitive profiles influence
    the quality of life of patients with Parkinson’s disease in multi-dimensional ways.
    MeSH terms: Anxiety; Anxiety Disorders; Attention; Cognition; Cross-Sectional Studies; Dementia; Depression; Humans; Memory, Short-Term; Movement; Parkinson Disease; Quality of Life
  13. Sasongko TH, Zabidi-Hussin Z, Othman NH, Van Rostenberghe H
    Malays J Med Sci, 2015 Nov;22(6):47-53.
    PMID: 28223885 MyJurnal
    Malaysia is advancing and nearly on pace with the international scientific community in human genetics and human genomics research. However, this research poses unique challenges. Although Malaysia already regulates medical genetic services, these regulations are insufficient for coping with the ethical issues emerging from recent genomic technologies. The Universiti Sains Malaysia recently created in-house guidelines and an informed consent template for genetic and genomic research. This article presents these guidelines and the informed consent template and discusses the justification and the background of the initiative. We also propose recommendations pertaining to local social studies and regulatory arrangements.
    MeSH terms: Humans; Informed Consent; Malaysia; Research; Social Sciences; Genomics; Genetic Services
  14. Abdullah Suhaimi SA, Mohamed A, Ahmad M, Chelliah KK
    Malays J Med Sci, 2015 Nov;22(6):40-46.
    PMID: 28223884 MyJurnal
    BACKGROUND: Most women are reluctant to undergo breast cancer screenings due to the pain and anxiety they experience. Sectional three-dimensional (3-D) breasttomosynthesis was introduced to improve cancer detection, but breast compression is still used for the acquisition of images. This study was conducted to investigate the effects of reduced compression force on pain, anxiety and image quality in digital breast tomosynthesis (DBT).

    METHODS: A total of 130 women underwent screening mammography using convenience sampling with standard and reduced compression force at the breast clinic. A validated questionnaire of 20 items on the state anxiety level and a 4-point verbal rating scale on the pain level were conducted after the mammography. Craniocaudal (CC) and mediolateral oblique (MLO) projections were performed with standard compression, but only the CC view was performed with reduced compression. Two independent radiologists evaluated the images using image criteria scores (ICS) and the Breast Imaging-Reporting and Data System (BI-RADS).

    RESULTS: Standard compression exhibited significantly increased scores for pain and anxiety levels compared with reduced compression (P < 0.001). Both radiologists scored the standard and reduced compression images as equal, with scores of 87.5% and 92.5% for ICS and BI-RADS scoring, respectively.

    CONCLUSIONS: Reduced compression force in DBT reduces anxiety and pain levels without compromising image quality.

    MeSH terms: Anxiety; Breast; Breast Neoplasms; Female; Humans; Mammography; Pain; Surveys and Questionnaires; Early Detection of Cancer; Radiologists
  15. Sandhu SS, Ismail NH, Rampal KG
    Malays J Med Sci, 2015 Nov;22(6):26-31.
    PMID: 28223882 MyJurnal
    BACKGROUND: The Perceived Stress Scale-10 (PSS-10) is widely used to assess stress perception. The aim of this study was to translate the original PSS-10 into Malay and assess the reliability and validity of the Malay version among nurses.

    METHODS: The Malay version of the PSS-10 was distributed among 229 nurses from four government hospitals in Selangor State. Test-retest reliability and concurrent validity was conducted with 25 nurses with the Malay version of the Depression Anxiety Stress Scales (DASS) 21. Cronbach's alpha, confirmatory factor analysis (CFA), intraclass correlation coefficient and Pearson's r correlation coefficient were used to determine the psychometric properties of the Malay PSS-10.

    RESULTS: Two factor components were yielded through exploratory factor analysis with eigenvalues of 3.37 and 2.10, respectively. Both of the factors accounted for 54.6% of the variance. CFA yielded a two-factor structure with satisfactory goodness-of-fit indices [x(2)/df = 2.43; comparative fit index (CFI) = 0.92, goodness-of-fit Index (GFI) = 0.94; standardised root mean square residual (SRMR) = 0.07 and root mean square error of approximation (RMSEA) = 0.08 (90% CI = 0.07-0.09)]. The Cronbach's alpha coefficient for the total items was 0.63 (0.82 for factor 1 and 0.72 for factor 2). The intraclass correlation coefficient (ICC) was 0.81 (95% CI: 0.62-0.91) for test-retest reliability testing after seven days. The total score and the negative component of the PSS-10 correlated significantly with the stress component of the DASS-21: (r = 0.61, P < 0.001) and (r = 0.56, P < 0.004), respectively.

    CONCLUSION: The Malay version of the PSS-10 demonstrated a satisfactory level of validity and reliability to assess stress perception. Therefore, this questionnaire is valid in assessing stress perception among nurses in Malaysia.

    MeSH terms: Anxiety; Depression; Factor Analysis, Statistical; Government; Malaysia; Perception; Psychometrics; Surveys and Questionnaires; Translating; Reproducibility of Results; Educational Personnel
  16. Ishak I, Rosli FD, Mohamed J, Mohd Ismail MF
    Malays J Med Sci, 2015 Nov;22(6):11-20.
    PMID: 28223880 MyJurnal
    BACKGROUND: Microwave is the most reliable sample digestion method. However, it requires expensive microwave digester automation and has relatively low productivity. In this study, three non-automated digestion methods, i.e. wet acid digestion using nitric acid (HNO3) and hydrogen peroxide (H2O2), wet acid digestion using HNO3, and dry washing, are compared in order to determine the best approach.

    METHODS: Certified reference material IAEA-086 (International Atomic Energy Agency, Austria) and hair and nail samples from 20 female students of Universiti Kebangsaan Malaysia, aged 19 to 30 years, were collected and analysed using the three digestion methods.

    RESULTS: For hair samples, analysis of variance of repeated measures showed significant differences in the level of all elements (P < 0.001) between the three methods. For nail samples, only the copper (Cu) level showed no significant difference (P = 0.100) between methods. Wet acid digestion using HNO3 and H2O2 showed the best within- and between-run relative standard deviation (RSD) values, with within-run RSD for all elements, except for selenium (Se), < 5%. The between-run precision ranges from 6.14% to 17.96% for hair and from 3.53% to 11.52% for nail samples. Wet acid digestion using HNO3 and H2O2 showed both good accuracy and precision for manganese (Mn) and magnesium (Mg), with percentage recoveries of 110% and 96.9%, respectively. All elements show higher method detection limit (MDL) values than the previous study: 0.05 μg/g Mg for wet acid digestion using HNO3, 0.02 μg/g Se for wet acid digestion using HNO3 and H2O2, and 0.2 μg/g Mg for dry ash method.

    CONCLUSION: Wet acid digestion using HNO3 and H2O2 proved to be the best method in terms of precision, accuracy, recovery, and MDL. However, only Mn and Mg showed adequate precision, accuracy, and percentage of recovery.

    MeSH terms: Adult; Austria; Automation; Copper; Data Collection; Female; Hair; Humans; Hydrogen Peroxide; International Agencies; Magnesium; Malaysia; Manganese; Microwaves; Nuclear Energy; Selenium; Nitric Acid; Young Adult; Limit of Detection
  17. Goh KG, Shanthi V
    Malays J Med Sci, 2015 Sep;22(5):98-102.
    PMID: 28239275 MyJurnal
    A 33-year-old lady presented to the emergency department (ED) of Kuala Lumpur Hospital with subacute onset of headaches, irritability, and vomiting. Neurological examination revealed a restless agitated patient, poor responses to verbal commands with a Glasgow Coma Scale of 14/15, photophobia, blurred nasal margins with generalised weakness, hyperreflexia, and downgoing plantars. Computed tomography (CT) of the brain showed evidence of biparietal infarction with an empty delta sign. Urgent magnetic resonance imaging and venography (MRI/MRV) of the brain in the ED showed evidence of thrombosis of the superior sagittal sinus extending to the torcular herophili, straight sinus, transverse sinuses, sigmoid sinuses, and proximal internal jugular veins. The precipitating factor for the thrombosis was possibly oral contraceptive pill usage, which she had been taking for a month. She was treated aggressively with anticoagulation. The patient subsequently improved symptomatically and achieved full neurological recovery. In this patient, early recognition of the clinical symptoms and a CT scan with confirmation by MRI/MRV of the brain enabled the prompt diagnosis and treatment of cerebral venous sinus thrombosis with a good clinical outcome.
    MeSH terms: Brain; Contraceptives, Oral; Cranial Sinuses; Emergency Service, Hospital; Female; Headache; Humans; Infarction; Jugular Veins; Magnetic Resonance Imaging; Phlebography; Reflex, Abnormal; Colon, Sigmoid; Sinus Thrombosis, Intracranial; Thrombosis; Tomography, X-Ray Computed; Vomiting; Glasgow Coma Scale; Precipitating Factors; Photophobia; Superior Sagittal Sinus; Transverse Sinuses
  18. Abad, Amin Talebi Bezmin, Ierardi, Enzo, Lee, Yeong Yeh
    MyJurnal
    The existence of any infectious agent in a highly acidic human stomach is contentious, but
    the chance finding of Helicobacter pylori is by no means an accident. Once H. pylori colonises the
    gastric mucosa, it can persist for a lifetime, and it is intriguing why our immune system is able to
    tolerate its existence. Some conditions favour the persistence of H. pylori in the stomach, but other
    conditions oppose the colonisation of this bacterium. Populations with high and extremely low
    prevalence of H. pylori provide useful insights on the clinical outcomes that are associated with this
    type of infection. Adverse clinical outcomes including peptic ulcer disease and gastric cancer depend
    on a delicate balance between a harmless inflammation and a more severe kind of inflammation. Is
    the only good H. pylori really a dead H. pylori? The jury is still out.
    MeSH terms: Accidents; Gastric Mucosa; Humans; Immune System; Inflammation; Peptic Ulcer; Stomach Neoplasms; Prevalence; Helicobacter pylori; Helicobacter Infections
  19. Lugova, Halyna, Mon, Aye Aye, Daher, Aqil Mohammad, Adlina Suleiman
    MyJurnal
    Background: Stigma and discriminatory attitudes (SDAs) have a negative impact on human
    immunodeficiency virus (HIV) prevention, testing, and treatment as well as on family and social
    networks. There is a lack of understanding about HIV-related SDAs among people living outside
    large cities. This study is aimed to determine the level of HIV-related SDAs among a semi-urban
    populationinMalaysiaandtocomparetheSDAresultsamongpeoplewithdifferentsociodemographic
    characteristics.
    Methods: A sample of 106 respondents was generated by convenience sampling during the
    screening campaign in Alor Gajah, Malaysia. Data collection was carried out based on a pre-tested
    questionnaire via face-to-face interviews.
    Results: More than half of the respondents (62.3%) thought that an HIV-positive teacher
    should not be allowed to continue teaching at school; 81.1% were unsure or were unwilling to care for
    their family member with AIDS at home; 81.2% thought children with HIV/AIDS should not continue
    to be raised in families; and 77.3% thought they would not reveal if a family member had HIV/AIDS.
    Conclusion: Priority should be given to evidence-based interventions to reduce HIV-related
    SDAs. This study did not reveal any significant relationship between sociodemographic profiles and
    HIV-related SDAs. Therefore, further research with a larger sample size is needed to investigate the
    underlying causes of HIV-related SDAs.
    MeSH terms: Acquired Immunodeficiency Syndrome; Attitude; Child; Cities; Humans; Malaysia; Surveys and Questionnaires; Research; Sample Size; Social Stigma
  20. Senthil MP, Salowi MA, Bujang MA, Kueh A, Siew CM, Sumugam K, et al.
    Malays J Med Sci, 2015 Sep;22(5):57-63.
    PMID: 28239269 MyJurnal
    OBJECTIVES: To develop a simple prediction model for the pre-screening of Retinopathy of Prematurity (ROP) among preterm babies.

    METHODS: This was a prospective study. The test dataset (January 2007 until December 2010) was used to construct risk prediction models, and the validation dataset (January 2011 until March 2012) was used to validate the models developed from the test dataset. Two prediction models were produced using the test dataset based on logistic regression equations in which the development of ROP was used as the outcome.

    RESULTS: The sensitivity and specificity for model 1 [gestational age (GA), birth weight (BW), intraventricular haemorrhage (IVH) and respiratory distress syndrome (RDS)] was 82 % and 81.7%, respectively; for model 2, (GA and BW) the sensitivity and specificity were 80.5% and 80.3%, respectively.

    CONCLUSION: Model 2 was preferable, as it only required two predictors (GA and BW). Our prediction model can be used for early detection of ROP to avoid poor outcomes.

    MeSH terms: Birth Weight; Gestational Age; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Prospective Studies; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity; Logistic Models
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