Affiliations 

  • 1 College of Health Sciences, Saudi Electronic University, Riyadh, Saudi Arabia
  • 2 College of Applied Medical Science, Jouf University, Sakaka, Saudi Arabia
  • 3 Healthcare Model, General Directorate of Health Affairs-Najran, Saudi Arabia
  • 4 Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, Sudan
  • 5 Dhahran Aljnoob Health Sector-Asser, Saudi Arabia
  • 6 Najran General Directorate of Health Affairs, Saudi Arabia
  • 7 College of Medicine and Health Sciences, Sana'a University, Yemen
  • 8 Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, UK
  • 9 Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Azhar University, Gaza, State of Palestine
  • 10 College of Applied Medical Sciences, Shaqra University, Saudi Arabia
  • 11 Hampshire Hospitals NHS Foundation Trust and Health Education, UK
  • 12 Clinical Laboratory Sciences Department, College of Applied Medical Science, King Saud University, Riyadh, Saudi Arabia
  • 13 Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Biomed Res Int, 2022;2022:4620037.
PMID: 35224093 DOI: 10.1155/2022/4620037

Abstract

COVID-19 is a global pandemic viral infection that has affected millions worldwide. Limited data is available on the effect of COVID-19 on hematological parameters in Saudi Arabia. This study is aimed at examining the role of hematological parameters among COVID-19 patients admitted to King Khalid Hospital in Najran, Saudi Arabia. This is a retrospective, hospital-based study of 514 cases who were recruited during August to October 2020. 257 COVID-19 patients formed the study group, and a further 257 negative subjects formed the control group. Anemia was significantly elevated in positive subjects over controls (respectively, 64.2% and 35.8%), with patients 2.5 times more likely to be anemic (p < 0.01). Thrombocytopenia was higher in patients over controls (respectively, 62% and 38%), with patients ~1.7 times more likely to be thrombocytopenic (p < 0.01). Moreover, leukopenia was significantly higher in patients over controls (respectively, 71% and 29%), with positive subjects ~2.6 times more likely to be leukopenic. Our study results indicate that mild anemia associated with leukopenia may have diagnostic value for COVID-19. Careful assessment of hematological parameters, at baseline and throughout the disease path, will assist physicians in formulating personalized approaches to treatment and promptly offer intensive care to those in greater need.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.