Affiliations 

  • 1 Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2 Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
PLoS One, 2026;21(11):e0359831.
PMID: 42986898 DOI: 10.1371/journal.pone.0359831

Abstract

BACKGROUND: There are limited studies comparing Hepatus (HP), a novel visual transient elastography device with Fibroscan (FS), one of the most studied and validated non-invasive tests in the field of hepatology.

METHODOLOGY: HP and FS examinations were performed on patients with chronic liver disease by two operators, healthcare providers from different background, twice on each patient, at two different time points, independent of each other.

RESULTS: The data for 158 patients with 1264 examinations was analysed. There was moderate to strong correlation for attenuation parameter (Spearman's rho 0.67, p S0, > S1 and >S2 and substantial agreement for diagnosis of unlikely and likely compensated advanced chronic liver disease. The interquartile range (IQR) for attenuation parameter and IQR/median for LSM were lower for HP compared with FS (12 dB/m vs 33 dB/m, p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.