COMT haplotype analyses in Malaysians with schizophrenia

Tee SF 1 , Tang PY , Loh HC

Affiliations 

  • 1 Department of Chemical Engineering, Faculty of Engineering and Science, Universiti Tunku Abdul Rahman, Jalan Genting Kelang, Setapak, 53300 Kuala Lumpur, Malaysia
Psychiatry Res, 2012 Jan 30;195(1-2):83-4.
PMID: 21872942 DOI: 10.1016/j.psychres.2011.07.039

Abstract

The present study included a total 261 patients with schizophrenia and 261 healthy controls to replicate the genetic association between the cathechol-o-methyltransferase gene and schizophrenia using a haplotype block-based gene-tagging. The G-G-G haplotype was found to show a highly significant association with schizophrenia.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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