Four tetracyclic oxindole alkaloids and a taberpsychine derivative from a Malayan Tabernaemontana

Lim KH 1 , Sim KM 2 , Tan GH 1 , Kam TS 3

Affiliations 

  • 1 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • 2 Department of Chemical Science, Faculty of Science, Engineering and Technology, Universiti Tunku Abdul Rahman, Jalan Universiti, Bandar Barat, 31900 Kampar, Perak, Malaysia
  • 3 Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: tskam@um.edu.my
Phytochemistry, 2009 Jun;70(9):1182-1186.
PMID: 19643450 DOI: 10.1016/j.phytochem.2009.06.010

Abstract

Four tetracyclic oxindole alkaloids, 7(R)- and 7(S)-geissoschizol oxindole (1 and 2), 7(R),16(R)- and 7(S),16(R)-19(E)-isositsirikine oxindole (3 and 4), in addition to a taberpsychine derivative, N(4)-demethyltaberpsychine (5), were isolated from the Malayan Tabernaemontana corymbosa and the structures were established using NMR and MS analysis.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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