Affiliations 

  • 1 Department of Cardiovascular Medicine, Nippon Medical School, Bunkyō, Tokyo, Japan
  • 2 National Heart Centre Singapore, Singapore, Singapore
  • 3 Division of Cardiology, Department of Internal Medicine, National Cerebral and Cardiovascular Center Hospital, Suita, Osaka, Japan
  • 4 Department of Cardiology, School of Medicine, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan
  • 5 Division of Cardiovascular Medicine, Department of Internal Medicine, Toho University Omori Hospital, Ōta, Tokyo, Japan
  • 6 Division of Cardiology, Department of Internal Medicine, Kinki University School of Medicine, Higashiōsaka, Osaka, Japan
  • 7 VA Medical Center, University of Minnesota, Minneapolis, MN, USA
ESC Heart Fail, 2018 04;5(2):297-305.
PMID: 29055972 DOI: 10.1002/ehf2.12228

Abstract

AIMS: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are increasingly frequent in Asia and commonly coexist in patients. However, the prevalence of COPD among Asian patients with HF and its impact on HF treatment are unclear.

METHODS AND RESULTS: We compared clinical characteristics and treatment approaches between patients with or without a history of COPD, before and after 1:2 propensity matching (for age, sex, geographical region, income level, and ethnic group) in 5232 prospectively recruited patients with HF and reduced ejection fraction (HFrEF, <40%) from 11 Asian regions (Northeast Asia: South Korea, Japan, Taiwan, Hong Kong, and China; South Asia: India; Southeast Asia: Thailand, Malaysia, Philippines, Indonesia, and Singapore). Among the 5232 patients with HFrEF, a history of COPD was present in 8.3% (n = 434), with significant variation in geography (11.0% in Northeast Asia vs. 4.7% in South Asia), regional income level (9.7% in high income vs. 5.8% in low income), and ethnicity (17.0% in Filipinos vs. 5.2% in Indians) (all P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.