Affiliations 

  • 1 Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK & NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
  • 2 Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK
  • 3 School of Health Sciences, University of East Anglia, Norwich, UK
  • 4 Department of Population Health Sciences, School of Population Health and Environmental Sciences, King's College London, London, UK
  • 5 Ageing and Age-Associated Disorders Research Group, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Int Psychogeriatr, 2019 10;31(10):1491-1498.
PMID: 30522546 DOI: 10.1017/S1041610218002065

Abstract

OBJECTIVES: To determine the relationship between falls and deficits in specific cognitive domains in older adults.

DESIGN: An analysis of the English Longitudinal Study of Ageing (ELSA) cohort.

SETTING: United Kingdom community-based.

PARTICIPANTS: 5197 community-dwelling older adults recruited to a prospective longitudinal cohort study.

MEASUREMENTS: Data on the occurrence of falls and number of falls, which occurred during a 12-month follow-up period, were assessed against the specific cognitive domains of memory, numeracy skills, and executive function. Binomial logistic regression was performed to evaluate the association between each cognitive domain and the dichotomous outcome of falls in the preceding 12 months using unadjusted and adjusted models.

RESULTS: Of the 5197 participants included in the analysis, 1308 (25%) reported a fall in the preceding 12 months. There was no significant association between the occurrence of a fall and specific forms of cognitive dysfunction after adjusting for self-reported hearing, self-reported eyesight, and functional performance. After adjustment, only orientation (odds ratio [OR]: 0.80; 95% confidence intervals [CI]: 0.65-0.98, p = 0.03) and verbal fluency (adjusted OR: 0.98; 95% CI: 0.96-1.00; p = 0.05) remained significant for predicting recurrent falls.

CONCLUSIONS: The cognitive phenotype rather than cognitive impairment per se may predict future falls in those presenting with more than one fall.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.