Lactobacillus plantarum USM8613 Aids in Wound Healing and Suppresses Staphylococcus aureus Infection at Wound Sites

Ong JS 1 , Taylor TD 2 , Yong CC 1 , Khoo BY 3 , Sasidharan S 3 , Choi SB 4 Show all authors , Ohno H 5 , Liong MT 6

Affiliations 

  • 1 School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia
  • 2 Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences, Yokohama, 230-0045, Japan
  • 3 Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800, Penang, Malaysia
  • 4 School of Data Sciences, Perdana University, 43400, Selangor, Malaysia
  • 5 USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800, Penang, Malaysia. hiroshi.ohno@riken.jp
  • 6 School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia. mintze.liong@usm.my
Probiotics Antimicrob Proteins, 2020 03;12(1):125-137.
PMID: 30659503 DOI: 10.1007/s12602-018-9505-9

Abstract

This study aimed to elucidate the targets and mechanisms of anti-staphylococcal effects from bioactive metabolites produced by lactic acid bacteria. We aimed to better understand the safety and efficacy of these bioactive metabolites in in vivo systems, typically at topical sites. The cell-free supernatant and protein-rich fraction from Lactobacillus plantarum USM8613 inhibited staphyloxanthin biosynthesis, reduced (p 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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