Affiliations 

  • 1 Department of Oncology-Pathology, Karolinska Institute and University Hospital, SE-17176 Stockholm, Sweden
  • 2 Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden
  • 3 Department of Cardiology and Department of Health, Medicine and Caring Sciences, Linkoping University, Linkoping, Sweden
  • 4 Julius Centre University of Malaya, Faculty of Medicine, University of Malaya, 50603 Lembah Pantai, Kuala Lumpur, Malaysia
  • 5 Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA
  • 6 Heart and Vascular Theme, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
  • 7 Department of Cardiology and Department of Health, Medicine and Caring Sciences, Norrkoping, Sweden
Eur Heart J Qual Care Clin Outcomes, 2020 04 01;6(2):147-155.
PMID: 31328233 DOI: 10.1093/ehjqcco/qcz039

Abstract

AIMS: Heart failure (HF) patients diagnosed with breast cancer (BC) may have a higher risk of death, and different HF presentation and treatment than patients without BC.

METHODS AND RESULTS: A total of 14 998 women with incident HF (iHF) or prevalent HF (pHF) enrolled in the Swedish HF Registry within and after 1 month since HF diagnosis, respectively, between 2008 and 2013. Patients were linked with the National Patient-, Cancer-, and Cause-of-Death Registry. Two hundred and ninety-four iHF and 338 pHF patients with BC were age-matched to 1470 iHF and 1690 pHF patients without BC. Comorbidity and treatment characteristics were compared using the χ2 tests for categories. Cox proportional hazard models assessed the hazard ratio (HR) and 95% confidence intervals (95% CIs) of all-cause and cardiovascular mortality among HF patients with and without BC. In the pHF group, BC patients had less often myocardial infarction (21.6% vs. 28.6%, P 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.