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Case Report: Case Series of Human Plasmodium knowlesi Infection on the Southern Border of Thailand

Ngernna S 1 , Rachaphaew N 2 , Thammapalo S 3 , Prikchoo P 3 , Kaewnah O 4 , Manopwisedjaroen K 2 Show all authors , Phumchuea K 2 , Suansomjit C 2 , Roobsoong W 2 , Sattabongkot J 2 , Cui L 5 , Nguitragool W 1

Affiliations 

  • 1 Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
  • 2 Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
  • 3 Office of Disease Prevention and Control Region 12 Songkhla, Department of Disease Control, Ministry of Public Health, Songkhla, Thailand
  • 4 Vector-Borne Diseases Control Center 12.2, Songkhla, Department of Disease Control, Ministry of Public Health, Songkhla, Thailand
  • 5 Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida
Am J Trop Med Hyg, 2019 12;101(6):1397-1401.
PMID: 31595871 DOI: 10.4269/ajtmh.19-0063

Abstract

Although human infections of Plasmodium knowlesi have been found throughout Southeast Asia, most cases originated from Malaysian Borneo. In Thailand, P. knowlesi malaria was considered extremely rare. However, during October 2017-September 2018, there was a surge in the number of reported P. knowlesi cases. Here, a series of six cases of P. knowlesi malaria found during this period in Songkhla and Narathiwat provinces of southern Thailand are presented. All cases were confirmed by polymerase chain reaction. The unprecedented case number in the affected area is a warning sign of an increasing P. knowlesi burden in the south of Thailand.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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