RANK, RANKL, and OPG in recurrent solid/multicystic ameloblastoma: their distribution patterns and biologic significance

Siar CH 1 , Tsujigiwa H 2 , Ishak I 3 , Hussin NM 4 , Nagatsuka H 5 , Ng KH 6

Affiliations 

  • 1 Professor of Oral Pathology and Oral Medicine, Department of Oro-Maxillofacial Surgical and Medical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia. Electronic address: Siarch@um.edu.my
  • 2 Professor of Histopathology, Laboratory of Histopathology, Department of Life Science, Faculty of Science, Okayama University of Science, Okayama, Japan
  • 3 Senior Lecturer and Consultant Oral and Maxillofacial Surgeon, Department of Oro-Maxillofacial Surgical and Medical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
  • 4 Master of Clinical Dentistry (Oral Medicine and Oral Pathology) Resident, Department of Oro-Maxillofacial Surgical and Medical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
  • 5 Professor of Oral Pathology and Medicine, Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan
  • 6 Former Director and Senior Consultant Oral Pathologist, Unit of Stomatology, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia
Oral Surg Oral Med Oral Pathol Oral Radiol, 2015 Jan;119(1):83-91.
PMID: 25446507 DOI: 10.1016/j.oooo.2014.09.017

Abstract

To determine the distribution patterns of bone resorption regulators, receptor activator of nuclear factor κ-B (RANK), RANK ligand (RANKL), and osteoprotegerin (OPG) in recurrent ameloblastoma (RAs) and to clarify their impact on the biologic behavior of these neoplasms.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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