Displaying publications 1 - 20 of 252 in total

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  1. Fulltext Emphysematous aortitis: report of two cases and CT imaging findings
    Md Noh MSF, Abdul Rashid AM, Ar A, B N, Mohammed Y, A R E
    BJR Case Rep, 2017;3(3):20170006.
    PMID: 30363220 DOI: 10.1259/bjrcr.20170006
    Emphysematous aortitis is a rare condition that manifests through the presence of air within or surrounding the inflamed aorta. Aortic inflammation may result from either an infective or a non-infective cause. Recognition of this rare condition is important as the resultant clinical deterioration may be rapid and lead to inevitable death. Cross-sectional imaging, with its relatively wide availability, proves an important tool in the diagnosis and subsequent management of this condition. We report two such cases encountered in our centre, with particular focus on the imaging findings on CT.
  2. Fulltext The involvement of doctors in research activities in two major hospitals in Penang, Malaysia
    Abdul Rashid, K., Gomathy, S., Ab Manan, A.
    Malaysian Journal of Public Health Medicine, 2012;12(2):31-38.
    MyJurnal
    Majority of doctors show no interest in research although research is now a requirement and is being done in every field of medicine. The objective of this survey was to describe the involvement in research activities among doctors in Penang and Seberang Jaya hospitals in Penang. A self-administered questionnaire was used. A total of 302 doctors participated in the survey. The differences in age (p=
  3. Fulltext A cross-sectional study of hypertensive outpatients to determine the necessity of asking about erectile dysfunction symptoms
    Sharifuddin N, Abdul Aziz AF, Sheikh Hamzah M, Abdul Rashid R, Zainuddin Z, Wan Puteh SE, et al.
    South African Family Practice, 2011;53:384-389.
    Background: Erectile dysfunction (ED) is common amongst hypertensive men. Hypertensive patients often attribute it to antihypertensive drugs, although conflicting evidence linking ED with antihypertensive medication exists. The objectives were to determine the prevalence and severity of ED, the type of treatment sought, and the risk factors for ED among hypertensive men.
    Method: A cross-sectional survey conducted over six months from June to November 2008 at University Kebangsaan, Malaysia Medical Centre, Kuala Lumpur. Inclusion criteria included hypertensive men above 30 years old, with essential hypertension for at least three months. We excluded diabetics, a history of pelvic surgery and known psychiatric illnesses. The International Index of Erectile Function-5 (IIEF-5) assessment was used with a standardised checklist. We analysed data using SPSS, to assess the prevalence and association of ED with selected variables.
    Results: Of the 200 participants screened, 35.5% perceived that they had ED. However, prevalence increased to 69% after screening using an IIEF-5 questionnaire. Forty-eight per cent were reported to have moderate-to severe ED. ED was significantly associated with age (p-value = 0.0001). No significant associations were found between ED and the duration of the hypertension (p-value = 0.505), hypertension control (p-value > 0.05), smoking status (p-value = 0.858) or number of antihypertensive medication taken (p-value > 0.05). Among perceived and proven ED patients, traditional medicines were mainly used for treatment (18.3% and 17.2% respectively).
    Conclusion: ED is a problem among hypertensive patients. It was associated with age but not with hypertension duration, control, number of antihypertensive drugs or smoking. Physicians should enquire about ED symptoms in hypertensive patients, as most of them resorted to self-treatment with traditional medicines. © SAAFP.
  4. Diesel engine emission analysis using fuel from diverse emulsification methods
    Sugeng DA, Yahya WJ, Ithnin AM, Abdul Rashid MA, Mohd Syahril Amri NS, Abd Kadir H, et al.
    Environ Sci Pollut Res Int, 2018 Sep;25(27):27214-27224.
    PMID: 30030755 DOI: 10.1007/s11356-018-2760-1
    The focus of this work is to investigate the emission characteristics of a stationary diesel engine while utilizing an emulsion fuel from a novel preparation process. The emulsion preparation was performed in real time without using any surfactant. Instead of mechanically breaking the water down into droplets, the water is delivered thermally, by changing its phase from gas to liquid. Steam is used in this proposed process, where it will be converted into suspended water droplets once it meets colder diesel. The product is called steam-generated water-in-diesel emulsion fuel (S/D). The method is expected to reduce the moving components of a previous surfactant-less system; therefore, reducing costs and increasing the system reliability. The emission characteristics of S/D were compared with EURO 2 diesel (D2), and a conventional emulsion denoted as E10. E10 was prepared using 10% water (volumetric) and SPAN80 as a surfactant. The emission characterizations were carried out based on the exhaust gas of a single cylinder naturally aspirated CI engine fueled with D2, S/D, and E10. Compared to D2, both emulsions significantly reduced the emissions of nitrogen oxides (NOx) (E10 max ↓58.0%, S/D max ↓40.0%) and particulate matter (PM) (E10 max ↓20.0%, S/D max ↓57.0%).
  5. Fulltext Antiangiogenic activity of sophorolipids extracted from refined bleached deodorized palm olein
    Kithur Mohamed S, Asif M, Nazari MV, Baharetha HM, Mahmood S, Yatim ARM, et al.
    Indian J Pharmacol, 2019 4 30;51(1):45-54.
    PMID: 31031467 DOI: 10.4103/ijp.IJP_312_18
    OBJECTIVES: Sophorolipids (SLs) are a group of surface-active glycolipids produced by a type of nonpathogenic yeast Candida bombicola in the presence of vegetable oil through fermentation technology. SLs have shown antitumor activity; however, the mechanism of action underlying the anticancer activity of SLs is poorly understood. This work evaluated the anticancer activity of SLs fermented from palm oil by exploring its antiangiogenic activity.

    MATERIALS AND METHODS: The SLs that were fermented and further characterized for their biochemical activities. Cytotoxicity study was performed to assess cytostatic properties. A series of in vitro and ex vivo angiogenesis assay was also carried out. The relative fold change in the expression of p53 mRNA by SLs was also studied.

    RESULTS: Altogether, the data show that SLs derived from palm oil fermentation process inhibited neovascularization in the ex vivo tissue segments and also the endothelial cell proliferation between 50% and 65% inhibition as a whole. The palm oil derived SLs also caused downregulation of the suppression level of vascular endothelial growth factor and also upregulate the p53 mRNA level. The analytical studies revealed the presence of high amount of phenolic compounds but with relatively weak antioxidant activity. The gas chromatography-mass spectrometry studies revealed abundant amount of palmitic and oleic acid, the latter an established antiangiogenic agent, and the former being proangiogenic.

    CONCLUSION: Therefore, it can be concluded from this study that SLs derived from fermented palm oil have potent antiangiogenic activity which may be attributed by its oleic acid component.

  6. Fulltext rac-Ethyl rel-(2R,3R,4S)-4-hy-droxy-1,2-dimethyl-5-oxopyrrolidine-3-carboxyl-ate
    Abdul Rashid FNA, Bacho MZ, Hamali MA, Slawin AMZ, Mohammat MF, Shamsujunaidi R, et al.
    IUCrdata, 2023 Feb;8(Pt 2):x230075.
    PMID: 36911075 DOI: 10.1107/S2414314623000755
    The asymmetric unit of the title compound, C9H15NO4, consists of a functionalized pyrrolidine ring having an envelope conformation, synthesized as an ethyl ester. The mol-ecule has three chiral centres and crystallized as a racemic mixture. In the crystal, mol-ecules are linked by pairwise O-H⋯O bonds, generating dimers with twofold rotational symmetry.
  7. Fulltext A life-threatening condition - ruptured ectopic pregnancy with negative urine pregnancy test: A case report
    Mohamad F, Yahya AS, Abdul Rashid A, Devaraj NK, Abdul Manap AH
    Malays Fam Physician, 2021 Mar 25;16(1):121-123.
    PMID: 33948151 DOI: 10.51866/cr1117
    Ectopic pregnancy is an extra-uterine pregnancy and is a potentially life-threatening condition that can lead to death from intra-peritoneal hemorrhage. This case reports a rare occurrence of ruptured tubal pregnancy in which the patient presented early with abdominal pain and a negative urine pregnancy test but subsequently presented again with evidence of intra-peritoneal hemorrhage. A negative urine pregnancy test is often used to rule out pregnancy, but it is not 100% sensitive. Complete assessment is critical in this important diagnosis in order to plan for the appropriate emergency management.
  8. Estimation of body height from spinal length measurements using post-mortem computed tomographic images
    Zyoud TYT, Abdul Rashid SN, Suppiah S, Mahmud R, Kabeer A, Abd Manaf R, et al.
    Malays J Pathol, 2020 Dec;42(3):423-431.
    PMID: 33361724
    INTRODUCTION: Post-mortem computed tomography (PMCT) provides information that helps in the determination of the cause of death and corpse identification of disaster victims. One of the methods for corpse identification includes assessment of the body stature. There is a lack of post-mortem imaging studies that focus on the anthropometric assessment of corpses. Our aim was to identify the relationship between cadaveric spine length and autopsy length (AL) among and autopsy length (AL) among a Malaysian population and derive a regression formula for the estimation of corpse body height using PMCT.

    MATERIALS AND METHODS: We retrospectively assessed 107 cadavers that had undergone conventional autopsy and PMCT. We made 5 measurements from the PMCT that included cervical length (CL), thoracic length (TL), lumbosacral length (LS), total column length of the spine, excluding the sacrum and coccyx (TCL), and ellipse line measurement of the whole spine, excluding the sacrum and coccyx (EL). We compared these anthropometric PMCT measurements with AL and correlated them using linear regression analysis.

    RESULTS: The results showed a significant linear relationship existed between TL and LS with AL, which was higher in comparison with the other parameters than the rest of the spine parameters. The linear regression formula derived was: 48.163 + 2.458 (TL) + 2.246 (LS).

    CONCLUSIONS: The linear regression formula derived from PMCT spine length parameters particularly thoracic and lumbar spine gave a finer correlation with autopsy body length and can be used for accurate estimation of cadaveric height. To the best of our knowledge, this is the first ever linear regression formula for cadaveric height assessment using only post mortem CT spine length measurements.

  9. A Massive Hemothorax in a Pregnant Woman: Role of Interventional Radiology
    Md Noh MSF, Abdul Rashid AM, Abdul Rahim E
    J Bronchology Interv Pulmonol, 2018 07;25(3):e30-e32.
    PMID: 29944591 DOI: 10.1097/LBR.0000000000000456
  10. Prediction models for early risk detection of cardiovascular event
    Purwanto, Eswaran C, Logeswaran R, Abdul Rahman AR
    J Med Syst, 2012 Apr;36(2):521-31.
    PMID: 22675726
    Cardiovascular disease (CVD) is the major cause of death globally. More people die of CVDs each year than from any other disease. Over 80% of CVD deaths occur in low and middle income countries and occur almost equally in male and female. In this paper, different computational models based on Bayesian Networks, Multilayer Perceptron,Radial Basis Function and Logistic Regression methods are presented to predict early risk detection of the cardiovascular event. A total of 929 (626 male and 303 female) heart attack data are used to construct the models.The models are tested using combined as well as separate male and female data. Among the models used, it is found that the Multilayer Perceptron model yields the best accuracy result.
  11. Reduction in arterial stiffness with angiotensin II antagonism and converting enzyme inhibition. A comparative study among malay hypertensive subjects with a known genetic profile
    Rehman A, Ismail SB, Naing L, Roshan TM, Abdul Rahman AR
    Am J Hypertens, 2007 Feb;20(2):184-9.
    PMID: 17261465 DOI: 10.1016/j.amjhyper.2006.07.015
    BACKGROUND: Data comparing the effect of losartan and perindopril on aortic stiffness among hypertensive subjects without A(1166)C polymorphism was not available.
    METHODS: The short-term and long-term effects of losartan (50 mg) and perindopril (4 mg) on aortic stiffness measured as carotid femoral pulse wave velocity (PWV) were compared in 39 middle-aged Malay subjects with mild-to-moderate hypertension in a 4-month, double-blind, randomized, controlled, parallel-design study.
    RESULTS: Four-month treatment with both drugs showed a significant reduction in blood pressure (BP) (P < .005) and PWV (P < .05) as compared to the baseline. On the other hand 1-month treatment showed a significant reduction in BP only in perindopril group (P < .05) but not in the losartan group. There was no significant reduction in pulse pressure and PWV after 1 month treatment by both drugs. No significant difference was seen in reduction in BP after 1 month and 4 months treatment between the two drugs. Similarly no significant difference was seen in reduction in PWV between the two drugs after 1 month (P = .613) and 4 months (P = .521) of treatment. Reduction in PWV by losartan (r = 0.470) and perindopril (r = 0.457) correlated significantly only with reduction in DBP (P < .05) and remained significant even after controlling for reduction in DBP (P < .05). Reduction in PWV by both losartan and perindopril was independent of reduction in BP by these drugs.
    CONCLUSIONS: These results showed that long-term treatment with losartan shows similar pressure independent reduction in PWV as perindopril among Malay hypertensive subjects with a homogenous "AA" genotype for angiotensin II type 1 receptor and may serve as a suitable alternative to perindopril.
  12. Fulltext Development and validation of a new Prescription Quality Index
    Hassan NB, Ismail HC, Naing L, Conroy RM, Abdul Rahman AR
    Br J Clin Pharmacol, 2010 Oct;70(4):500-13.
    PMID: 20840442 DOI: 10.1111/j.1365-2125.2009.03597.x
    The aims were to develop and validate a new Prescription Quality Index (PQI) for the measurement of prescription quality in chronic diseases.
  13. Fulltext Teaching evidence based medicine to fourth year medical students at Cyberjaya University College of Medical Sciences, Malaysia
    Ab Manan N, Jahan N, Mohamad Alwi MN, Qureshi AM, Abdul Rahman AR
    Education in Medicine Journal, 2017;9(3):55-62.
    MyJurnal
    Background: Recently many medical schools have incorporated Evidence Based Medicine (EBM) as part of their undergraduate teaching. The aim is to provide a firm base of EBM to the medical students early on, so that they can understand the importance of EBM. Medical schools are encouraged to teach EBM to students but yet the education setting, learner level, modes of instruction, skills covered and teaching methods are not standardised and varies worldwide. In Cyberjaya University College of Medical Sciences (CUCMS), EBM was incorporated in the curriculum since 2009. EBM concepts was taught formally to the MBBS students during four weeks Research and Evidence Based Medicine Course (REBM). Students were exposed to the various thinking processes, formulation of clinical questions, searching evidence, intermediate biostatistics, research methodology and critical appraisal. Besides that, Good Clinical Practice (GCP) and research proposal development also include in the course. The objective of this paper is to describe
    CUCMS experience of teaching EBM for undergraduate medical students.
    Methods: This report analysed students feedback using a questionnaire which included a Likert scale and open-ended questions.
    Result: Overall, three batches of students gave positive feedbacks regarding the course with constructive suggestions on room for improvement.
    Conclusion: From our first three years’ experience in conducting the course, we concluded that the four-week EBM course offered was practical in instilling EBM principles.
  14. Effect of rosiglitazone/ramipril on preclinical vasculopathy in newly diagnosed, untreated diabetes and IGT patients: 1-year randomised, double-blind, placebo-controlled study
    Rahman S, Ismail AA, Ismail SB, Naing NN, Abdul Rahman AR
    Eur J Clin Pharmacol, 2007 Aug;63(8):733-41.
    PMID: 17565489 DOI: 10.1007/s00228-007-0315-3
    OBJECTIVE: To investigate whether pharmacological interventions with rosiglitazone/ramipril can reverse preclinical vasculopathy in newly diagnosed untreated patients with type 2 diabetes (T2DM) and impaired glucose tolerance (IGT).

    METHODS: In this randomised, double-blind, placebo-controlled study, 33 T2DM and 33 IGT patients were randomised to 4 mg rosiglitazone or 5 mg ramipril or placebo for 1 year. The subjects were newly diagnosed, untreated, normotensive, nonobese, nonsmoker, and nonhyperlipidaemic. Haemodynamic variables were measured at three treatment phases and pulse wave velocity (PWV) and augmentation index (AI) were measured throughout the treatment period.

    RESULTS: Rosiglitazone showed a significant reduction in PWV (p=0.039) and AI (p=0.031) and ramipril demonstrated a significant reduction of AI (p=0.025) in IGT in comparison to placebo on the 12th month of treatment. No significant difference was observed in PWV and AI in T2DM with rosiglitazone/ramipril in comparison to placebo during overall treatment period.

    CONCLUSIONS: Rosiglitazone significantly reversed preclinical vasculopathy in IGT as evident by significant decrease in PWV and AI after 1 year of treatment. Ramipril also reduced large artery stiffness as shown by significant decrease of AI after 1 year of treatment in IGT. Further trials are needed for a longer period of time, maybe with higher doses, to show whether rosiglitazone/ramipril can reverse preclinical vasculopathy in T2DM.
  15. Candidate gene polymorphisms and their association with hypertension in Malays
    Ghazali DM, Rehman A, Abdul Rahman AR
    Clin Chim Acta, 2008 Feb;388(1-2):46-50.
    PMID: 17977523 DOI: 10.1016/j.cca.2007.10.002
    BACKGROUND: Knowledge of candidate gene polymorphisms in a population is useful for a variety of gene-disease association studies, particularly for some complex traits. A single nucleotide variant of the angiotensinogene gene (AGT M235T) and endothelial nitric oxide synthase gene (eNOS G894T) have been associated with hypertension.
    METHOD: A cross-sectional study consisting of 200 hypertensives and 198 age- and sex-matched controls was conducted. Subjects involved in this study were pure Malay for 3 generations. The AGT M235T and eNOS G894T polymorphisms were determined by PCR-RFLP method.
    RESULTS: The distribution of M235T genotype in the population was 3.5% for MM, 30.4% for MT and 66.1% for TT. No significant difference was observed in genotype (chi(2)=1.30, p=0.52) and allele (chi(2)=0.87, p=0.35) frequencies among the 2 study group. In contrast, the distribution of genotypes for G894T was 74.1% for GG, 24.6% for GT and 1.3% for TT, respectively. Similarly, no significant difference was observed in genotype (chi(2)=0.94, p=0.33) and allele (chi(2)=0.60, p=0.44) frequencies between both study groups.
    CONCLUSION: The AGT M235T and eNOS G894T polymorphisms are unlikely to play an important role in the pathogenesis of hypertension in Malays.
    Study site: Outpatient clinic, Hospital Universiti Sains Malaysia (HUSM); government clinics, Kelantan, Malaysia.
  16. Fulltext Focus group discussions on female genital cutting
    Siti Nur Afiqah Zahari, Yufu Iguchi, Abdul Rashid
    Malaysian Journal of Medicine and Health Sciences, 2019;15(104):18-18.
    MyJurnal
    Introduction: Female Genital Cutting (FGC) is a sensitive issue as this topic is always associated with religion and culture in Malaysia. In the past, FGC is performed by the traditional midwives. However, this practice has been med-icalized nowadays. This study aimed to understand the reasons of performing FGC, the decision making, the practice and the future of FGC among rural community in Northern Malaysia. Methods: Focus group discussions (FGD) were conducted on three groups of young women aged 18-45, older women aged 45 and above and a group of married adult men. All of them were Malay Muslims who were conveniently selected from a rural village in Northern Malay-sia. A semi-structured interview guide was used to conduct the FGD focusing on the reasons, decision making, the practice and the future of FGC. Data was collected until saturation of information was achieved. These participants were chosen based on their willingness to take part in the discussion and also based on their personality of being talkative and able to give feedback to the questions. Results: The result of the interviews revealed that religion is the reason of practicing FGC. All of the participants from each FGD prefer to go to the doctor in the clinic compared to the traditional midwives. The men in this FGD mentioned that they rarely involved in the decision making of the FGC and only the mother or the grandmother to take the responsibility to decide. Conclusion: Generally, majority Malay Muslims community from the rural areas in Northern Malaysia believed that FGC is compulsory in Islam and they prefer to go to the doctors to perform FGC.
  17. Fulltext Seroprevalence, knowledge, attitude and practice regarding prevention of Hepatitis C among municipal waste collectors in Penang Island, Malaysia
    Surajudeen Abiola Abdulrahman, Siti Fatimah Kader Maideen, Fairuz Fadzilah Rahim, Abdul Rashid
    Journal of Clinical and Health Sciences, 2019;4(1):47-57.
    MyJurnal
    Introduction: This study aimed to determine the prevalence of Hepatitis C infection and the
    level of knowledge, attitude and practice regarding Hepatitis C prevention among municipal
    waste collectors in Penang Island, Malaysia. Methods: A cross-sectional study was
    conducted among a convenient sample of 184 adult male municipal waste collectors in
    Penang Island from January to May 2018. Respondents’ blood samples were obtained and
    evaluated for antibodies to Hepatitis C virus (anti-HCV), and questionnaires administered to
    them to collect information on sociodemographic variables and knowledge, attitude and
    practice regarding Hepatitis C prevention. The seroprevalence of Hepatitis C virus was
    estimated, and the association between sociodemographic variables and respondents’ level
    of knowledge, attitude and practice regarding Hepatitis C prevention was explored using a
    range of parametric and non-parametric statistical tests in SPSS version 23. Results were
    considered significant at p
  18. Fulltext Geospatial Water Productivity Index (WPI) for rice
    Md Rowshon Kamal, Mohd Amin Mohd Soom, Abdul Rashid Mohamed Shariff
    Pertanika Journal of Science & Technology, 2012;20(2):381-399.
    MyJurnal
    A GIS-based user-interface programme was developed to compute the geospatial Water ProductivityIndex (WPI) of a river-fed rice irrigation scheme in Northwest Selangor, Malaysia. The spatial analysisincludes irrigation blocks with sizes ranging from 20 to 300 ha. The amount of daily water use for eachirrigation block was determined using irrigation delivery model and stored in the database for both mainseason (August to December) and off season (February to May). After cut-off of the irrigation supply,a sub-module was used to compute the total water use including rainfall for each irrigation block. Therice yield data for both seasons were obtained from DOA (Department of Agriculture, Malaysia) of thescheme. Then, the Water Productivity Index (WPI) was computed for each irrigation block and spatialthematic map was also generated. ArcObjects and Visual Basic Application (VBA) programminglanguages were used to structure user-interface in the ArcGIS software. The WPI, expressed in termsof crop yield per unit amount of water used (irrigation and effective rainfall), ranged from 0.02 to 0.57kg/m3 in the main season and 0.02 to 0.40 in off season among irrigation blocks, respectively. Thedevelopment of the overall system and the procedure are illustrated using the data obtained from thestudy area. The approach could be used to depict the gaps between the existing and appropriate watermanagement practices. Suitable interventions could be made to fill the gaps and enhance water useefficiency at the field level and also help in saving irrigation water through remedial measures in theseason. The approach could be useful for irrigation managers to rectify and enhance decision-makingin both the management and operation of the next irrigation season.
  19. Fulltext Tuberculous Myelopathy Associated with Longitudinally Extensive Lesion: A Clinicoradiological Review of Reported Cases
    Md Noh MSF, Bahari N, Abdul Rashid AM
    J Clin Neurol, 2020 Jul;16(3):369-375.
    PMID: 32657056 DOI: 10.3988/jcn.2020.16.3.369
    Acute transverse myelitis is an inflammatory disorder of the spinal cord in which there is no evidence of spinal cord compression. Longitudinally extensive transverse myelitis (LETM) is a specific subtype of acute transverse myelitis that usually affects three or more vertebral levels and produces marked neurological deficits. While the most-common cause of LETM is neuromyelitis optica or neuromyelitis optica spectrum disorder, there are rare cases of other causes mimicking this condition, including tuberculosis (TB). We sought to review the clinicoradiological features of TB myelopathy associated with longitudinally extensive lesion, which may mimic LETM, in the English literature. We searched the PubMed, Google Scholar, Web of Science, and Scopus databases for relevant articles using search terms including "longitudinally extensive transverse myelitis," "tuberculosis," "TB spinal cord," and various combinations of these expressions. Full-text papers were selected without limiting the publication year. We also examined the reference lists of key papers to identify further articles that are potentially relevant. We found 10 cases in 7 papers describing TB myelopathy associated with longitudinally extensive lesion. The demographics, clinical features, relevant cerebrospinal fluid findings, and radiological findings were compiled and summarized. TB myelopathy associated with longitudinally extensive lesion is very rare, with no documented prevalence. Early and accurate diagnosis is important since the condition is potentially treatable.
  20. Fulltext Development of pseudo-subarachnoid hemorrhage secondary to hypoxic-ischemic injury due to bleeding pulmonary arterio-venous malformation
    Md Noh MSF, Abdul Rashid AM
    BMC Neurol, 2018 Sep 28;18(1):157.
    PMID: 30266082 DOI: 10.1186/s12883-018-1161-x
    BACKGROUND: The computed tomography (CT) finding of a pseudo-subarachnoid hemorrhage (SAH) may lead the treating physician into a diagnostic dilemma. We present a case of a pseudo-SAH in a patient with post-resuscitative encephalopathy, secondary to a newly diagnosed bleeding pulmonary arterio-venous malformation (AVM).

    CASE PRESENTATION: A 19-year-old female presented acutely with massive hemoptysis. Cardiopulmonary resuscitation (CPR) followed, and the patient was subsequently intubated for airway protection with intensive care unit (ICU) admission. Urgent CT angiography of the thorax showed a bleeding pulmonary AVM, with evidence of hemothorax. Non-contrasted cranial CT initially revealed cerebral edema. Day 3 post admission, repeat cranial CT showed worsening cerebral edema, with evidence of pseudo-SAH. Patient passed away the next day.

    CONCLUSIONS: Pseudo-SAH, if present, carries a poor prognosis. It should be recognized as a potential CT finding in patients with severe cerebral edema, due to various causes. The diagnosis is vital, to avoid wrongful treatment institution, as well as determination of cause of death.

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