Displaying publications 1 - 20 of 44 in total

Abstract:
Sort:
  1. Zamzil Amin, A., Baharudin, A., Shahid, H., Din Suhaimi, S., Nor Affendie, M.J.
    MyJurnal
    A tick in the ear is a very painful condition and removal is difficult because it grips firmly to the external auditory canal or tympanic membrane. Facial paralysis is a rarely reported localised neurological complication of an intra-aural tick infestation. The pathophysiology of localised paralysis is discussed, together with the safe way of handling patients with an intra-aural tick infestation.
  2. Amin A, Ali A, Kurunathan S, Cheong TG, Al-Jashamy KA, Jaafar H, et al.
    Histol Histopathol, 2009 05;24(5):559-65.
    PMID: 19283664 DOI: 10.14670/HH-24.559
    Vibrio cholerae is the causative agent of the infectious disease, cholera. The bacteria adhere to the mucosal membrane and release cholera toxin, leading to watery diarrhea. There are >100 serovars of V. cholerae, but the O1 and O139 serovars are the main causative agents of cholera. The present study aimed to compare the severity of intestinal mucosal infection caused by O1 El Tor and O139 V. cholerae in a rabbit ileal loop model. The results showed that although the fluid accumulation was similar in the loops inoculated with O1 and O139 V. cholerae, the presence of blood was detected only in the loops inoculated with the O139 serovar. Serosal hemorrhage was confirmed by histopathological examination and the loops inoculated with O139 showed massive destruction of villi and loss of intestinal glands. The submucosa and muscularis mucosa of the ileum showed the presence of edema with congested blood vessels, while severe hemorrhage was seen in the muscularis propria layer. The loops inoculated with O1 El Tor showed only minimal damage, with intact intestinal villi and glands. Diffuse colonies of the O139 serovar were seen to have infiltrated deep into the submucosal layer of the intestine. Although the infection caused by the O1 serovar was focal and invasive, it was more superficial than that due to O139, and involved only the villi. These observations were confirmed by immunostaining with O1 and O139 V. cholerae-specific monoclonal antibodies. The peroxidase reaction demonstrated involvement of tissues down to the submucosal layer in O139 V. cholerae infection, while in O1 El Tor infection, the reaction was confined mainly to the villi, and was greatly reduced in the submucosal region. This is the first reported study to clearly demonstrate the histopathological differences between infections caused by the O139 Bengal and O1 El Tor pathogenic serovars of V. cholerae.
  3. Muhammad Amin AU
    Med J Malaysia, 2013 Dec;68(6):471-2.
    PMID: 24632916
    We report a case of a 21 year old girl who presented with sudden onset of abdominal, back and bilateral leg pain, paralysis with unexpected collapse at home. Physical examination was suggestive of acute aortic occlusion. CTangiogram revealed multi-system thrombo-embolic shower. She proceeded to urgent aortic thrombectomy and fasciotomy of the bilateral lower limb. Further investigation revealed atrial myxoma and we report the patient's postoperative progress and eventual transfer to rehabilitation facility.
  4. Umi Kalthum, M.N., Amin, A., Syazarina, S.O., Faridah, H.A.
    MyJurnal
    A 42-year-old Malay gentleman presented with progressive painless blurring of vision on his left eye associated with ocular ache, redness and increasing proptosis. Examination revealed presence of relative afferent papillary defect with visual acuity of counting finger, and 6/6 on the right eye. Extraocular muscle movement of the left eye was restricted to ten percent in all directions. Computed tomography (CT) and magnetic resonance imaging (MRI) showed enhancing mass occupying the left orbital apex. Diagnosis of optic nerve sheath meningioma was made, and patient subsequently went for radiotherapy. His symptoms subsided completely, until he presented with similar visual complains, and fullness of the upper lid two years later. A repeated MRI showed enlargement of superior and lateral recti muscles with extension to lacrimal gland region. Biopsy of the lacrimal gland revealed inflammatory cells consistent of inflammatory pseudotumor. High dose systemic steroid was instituted, followed by slow tapering of oral steroid. His symptoms completely resolved, and latest visual acuity was 6/9, with no recurrence, to date.
  5. Hamzah N, Sarbon NM, Amin AM
    J Food Sci Technol, 2015 Aug;52(8):4773-84.
    PMID: 26243898 DOI: 10.1007/s13197-014-1622-1
    This study aimed to determine the effects of 2-5 wash cycles and the addition of tetrasodium pyrophosphate (TSPP) (0 %, 0.05 Surimi% and 0.1 % w/w)-with or without the addition of 0.4 % calcium chloride (CaCl2)-on the physical properties such as texture, colour, expressible moisture and microstructure of Cobia (Rachycentron canadum) surimi gel. The highest breaking force (484.85 g) was obtained with the addition 0.1 % TSPP alone on the fifth wash. However, a combination of 0.1 and 0.4 % CaCl2 in surimi gels at wash cycle 5 resulted in the highest degree of whiteness (86.8 %), as well as total expressible moisture (2.785 %) and deformation (17.11 mm). The highest surimi gel strength (6,923 g.mm) was obtained after three wash cycles with the addition of 0.1 % TSPP +0.4 % CaCl2. The physical properties of Cobia fish surimi gels were affected by the number of wash cycles and treatments with TSPP and CaCl2.
  6. Yong MH, Amin A, Mushawiahti M, Bastion ML
    Med J Malaysia, 2015 Dec;70(6):358-60.
    PMID: 26988210
    We report a case of a middle-aged gentleman with recalcitrant macular oedema (RMO) secondary to ischaemic central retinal vein occlusion (CRVO). He was given six injections of intravitreal ranibizumab (anti-VEGF) monthly. However, his visual acuity (VA) deteriorated and the macular oedema worsened. He then received an intravitreal dexamethasone implant eight months post-CRVO. His VA and macular oedema improved dramatically and significantly at first follow-up and remained stable at six months after implant. This case can be a reference for those who treating recalcitrant macular oedema. It shows the effect of an intravitreal dexamathasone implant might have in a patient with RMO due to CRVO. The patient enjoyed improvement of vision, with clinical evidence of reduction in central macular thickness (CMT) and with no serious adverse events after a single injection up to six months post implant.
  7. Nazima, S.A., Hanisah, A.H., Rona, A.N., Wong, H.S., Amin, A., Bastion, M.L.C., et al.
    Medicine & Health, 2016;11(2):245-256.
    MyJurnal
    Polypoidal choroidal vasculopathy (PCV) is a retinal disorder characterized
    by aneurismal polypoidal lesions in choroidal vasculature. PCV appears to
    preferentially affect pigmented individuals and is considerably high among Asians.
    Most reports on patterns of PCV around Asia are based on a homogenous race
    (e.g. Chinese, Japanese) and very few descriptions from a multiracial population
    like those seen in Malaysia. The present study aimed to describe the demographic
    features, clinical and investigative characteristics of PCV in a multiracial group at
    Universiti Kebangsaaan Malaysia Medical Centre (UKMMC). Ninety one eyes of 86
    PCV patients, comprising of Chinese (65.1%), Malays (31.4%), Indians (2.3%) and
    Eurasian (1.2%) were retrospectively reviewed. All underwent complete ophthalmic
    examination and investigations. Mean patient age was 70.4 years with a male
    preponderance (59.3%), and mostly unilateral presentation (94.1%). The logMAR
    mean presenting visual acuity was 0.78 ± 0.64. Polypoidal vascular lesions were
    located generally within the macula area (86.8%), manifesting mainly as submacular
    hemorrhage (59.3%). Interestingly a number of eyes (43.9%) had associated drusen.
    Optical coherence tomography largely demonstrated exudative changes (75.9%)
    and almost all patients (97.7%) had loss of external limiting membrane (ELM) and
    IS/OS interface. On indocyanine green angiography, majority of eyes had multiple
    polyps (82.4%) with ‘cluster’ (58.2%) being the commonest configuration. In
    conclusion, although the patterns of PCV in UKMMC were mainly similar to other
    Asian patients, a number of our patients had associated drusen. This indicates
    that PCV in our population could be a variant of neovascular age related macular
    degeneration and not solely idiopathic in nature.
  8. Jamaludin, M.A., Hashim, D.M., Rahman, R.A., Ramli, M.A., Majid, M.Z.A., Othman, R., et al.
    MyJurnal
    The halal food production industry is gaining greater attention among Muslim and non-Muslim
    majority countries, particularly due to the increase of global market demand. One of the critical
    areas in issuing halal certified food is the determination of allowable alcohol content in food
    and drinks. The level of alcohol content has not standardized in several standards and fatwa of
    Islamic scholars. In Islam, the alcohol in several fruit products is produced through fermentation
    process such as takhammur (wine making) and takhallul (vinegar making). The fermentation
    process gives an impact to the status of the food products either permissible or prohibited.
    Therefore, the purpose of this paper is to discuss on the determination of permissible alcohol
    and vinegar by fermentation process content in selected food products from Shariah and science
    perspectives. In doing so, the views of authentic of Islamic Law in this issue are supported by
    lab work approached. As a result, in the first phase there are three types of by products from
    takhammur, while two types of takhallul. All the products can be determine of the alcohol
    content and give an implication of the status either permissible (halal) or prohibited (haram).
    Hence, in juice considered as halal due to lower of alcohol content. While cider or alcoholic
    beverage is haram due to above alcohol level permitted which is above of the 1%. Besides,
    cider vinegar or vinegar is halal by the interpretation of hadith of permissible conversion from
    alcoholic to vinegar itself.
  9. Amin AKMR, Tanaka M, Al-Saari N, Feng G, Mino S, Ogura Y, et al.
    Syst Appl Microbiol, 2017 Jul;40(5):290-296.
    PMID: 28648725 DOI: 10.1016/j.syapm.2017.04.003
    Two phylogenetically distinct Vibrionaceae strains C4II189Tand C4V358Tisolated from reef seawater off Ishigaki Island, Japan, in 2014 were studied with advanced genome-based taxonomy approaches. All aspects of phylogenetic (16S rRNA phylogeny, MLSA), phenotypic and genetic (ANI, DDH, AAI, and the number of core genes) cohesions between the two identified species were high enough to propose them as members of a new genus within the family Vibrionaceae. Consequently, an eighth genus Thaumasiovibrio gen. nov. is proposed that contains two new species Thaumasiovibrio occultus sp. nov. strain C4II189T(=DSM 101554T=JCM 31629T) (type species) and Thaumasiovibrio subtropicus sp. nov. strain C4V358T(=DSM 101555T=JCM 31630T). Thaumasiovibrio species were phylogenetically distinct from the other Vibrionaceae species based on pyrH gene sequences. The combination of catalase negative, sensitivity to vibriostatic agent O/129, and green colony formation on TCBS for the phylogenetically affiliated strains was the diagnostic features for the current tentative identification of this genus.
  10. Leal Filho W, Echevarria Icaza L, Emanche VO, Quasem Al-Amin A
    PMID: 29257100 DOI: 10.3390/ijerph14121600
    The impacts of climate changes on cities, which are home to over half of the world's population, are already being felt. In many cases, the intensive speed with which urban centres have been growing means that little attention has been paid to the role played by climatic factors in maintaining quality of life. Among the negative consequences of rapid city growth is the expansion of the problems posed by urban heat islands (UHIs), defined as areas in a city that are much warmer than other sites, especially in comparison with rural areas. This paper analyses the consistency of the UHI-related literature in three stages: first it outlines its characteristics and impacts in a wide variety of cities around the world, which poses pressures to public health in many different countries. Then it introduces strategies which may be employed in order to reduce its effects, and finally it analyses available tools to systematize the initial high level assessment of the phenomenon for multidisciplinary teams involved in the urban planning process. The analysis of literature on the characteristics, impacts, strategies and digital tools to assess on the UHI, reveals the wide variety of parameters, methods, tools and strategies analysed and suggested in the different studies, which does not always allow to compare or standardize the diagnosis or solutions.
  11. Rathna, R., Amin, A., Bastion, M.L.C., Mushawiahti, M.
    MyJurnal
    Phacoemulsification (PEA) is currently the procedure of choice for most cataract extraction. However, intra-operative complications may require the procedure to be converted to extracapsular cataract extraction (ECCE). We have evaluated the indications for conversion and visual outcomes in cases converted from phacoemulsification to ECCE. A retrospective review was performed on 33 eyes in which phacoemulsification was initiated and then converted to ECCE. The main parameters evaluated were indications for conversion and visual outcomes at 3 months. Thirty-three cases out of 1448 operations were identified from January 2013 to February 2014.The incidence of PEA converted to ECCE was 2.2%. The indications for ECCE conversion were posterior capsular rupture (PCR) in twenty-two cases, combined capsulorhexis extension with PCR in three cases, capsulorhexis extension and zonular dialysis in two cases respectively. Combined zonular dialysis with PCR, corneal toxicity, Descemet’s tear and obscured edge of capsulorhexis had one case each. Twenty-six (78%) cases had gain in vision, one (3%) case had unchanged vision and six (18%) cases had worsening of vision. The incidence of complicated phacoemulsification surgery requiring intra-operative conversion to ECCE was low in our study (2.2%). Seventy-eight percent of cases achieved final VA of 6/12 or better. Therefore, early recognition of complications and timely intra-operative conversion of PEA to ECCE may result in good visual outcome.
  12. Muhammad Najmi, K., Aida Zairani, M.Z., Mushawiahti, M., Bastion, M.L.C., Amin, A.
    MyJurnal
    Pneumatic retinopexy is known as one of the treatment options for a specific type of retinal detachment. It is done in
    an office setting and may be the most cost-effective means of retinal reattachment surgery. Location and size of the
    retinal break remain as the major criteria for a successful outcome. We describe a case that fulfilled all except one
    major criteria for pneumatic retinopexy and underwent multiple procedures but failed. Fluctuation in the resolution
    of the retinal detachment such as in this particular case suggested possibility of early treatment failure.
  13. Jamaludin, M.A., Amin, A., Fadzlillah, N. A., Kartika, B., Othman, R., Sani, S., et al.
    MyJurnal
    Vinegar is very popular as traditional ingredient for cooking, pickling, and preservation. It is made from sugar or starch by an alcoholic and acetous fermentation and produces ethanol as a by-product. Alcohol is prohibited to be consumed for Muslim or used as ingredient if it is exceeding the allowable limit as stated by Islamic Council in Malaysia. According to Fatwa Committee National Council of Islamic Religious Affairs Malaysia, natural occurrences of ethanol in food products are acceptable if the ethanol contents are less than 1% in beverages and 0.5% for flavoring or coloring substances for the purpose of stabilization. On the other hand, for specific vinegar product, as stated by Malaysian Food Act and Regulation, acetic acid content must be at least 4%. According to FAO/WHO, a product is to be labelled as vinegar if the acetic acid content is 6% and with a maximum residual alcohol content of 0.5%v/v for wine vinegar and 1%v/v for other vinegars. This study investigated the physiochemical properties of the vinegar from different sources of raw materials. Total solubility (TA) by using Brix method, pH, and alcohol and acetic acid content by GC-TOF/MS of 12 commercial vinegars from Malaysia and abroad were studied. The result shown that for pH value of commercial vinegar are ranged from 2.51-3.14°Brix from 2.10-40.73°Brix, acetic acid is ranged from 0.0253-0.1276% and ethanol content from 0-0.5911%. Thus, this study will come out with the clear observation on ethanol content in fermented product which is vinegar in order to categories the halalness of the product that available in Malaysia market especially the ones that are produced internationally. Lastly, as shown by the profiling study, vinegar that are imported internationally may contain some amount of alcohol in contrast with the one that locally produced in Malaysia and has Halal certification.
  14. Azmah Hanim, M.A., Mohamad Aznan, M.N., Muhammad Raimi, R., Muhammad Azrol Amin, A.
    MyJurnal
    The formation of intermetallic compound (IMC) layer at the interfaces of pad finishes has been studied.
    The growth of IMC layer as a reflow process and its properties were also discussed. In this study, solder
    alloy SAC237 (Sn: 99 wt.%, Ag: 0.3 wt.%, Cu: 0.7 wt.%), reinforced with 0.01 wt.% Multi-Walled
    Carbon Nanotubes (MWCNTs), was mixed to form a composite solder paste and soldered on Electroless
    Nickel Immersion Gold (ENIG) and Immersion Tin (ImSn) pad finishes. Reflow process was conducted
    in oven with specific reflow profile. The growth and properties of IMC layer were analysed using optical
    microscope with image analyser. Results showed that the thickness of IMC layer for ENIG and ImSn
    were 1.49 and 2.51 µm, respectively. Floating IMC and voids within the solder bulk and IMC layer
    were also identified in the samples. In addition, the measured wetting angle for ENIG and ImSn were
    16.21° and 34.32°, respectively.
  15. Balogun WG, Cobham AE, Amin A, Seeni A
    Neuroscience, 2018 03 15;374:323-325.
    PMID: 29427653 DOI: 10.1016/j.neuroscience.2018.01.062
    Neuroscience research and training in many African countries are difficult due to funding and infrastructure deficit. This has resulted in few neuroscientists within Africa. However, invertebrates such as Drosophila and Caenorhabditis elegans could provide the perfect answer to these difficulties. These organisms are cheap, easy to handle and offer a comparable advantage over vertebrates in neuroscience research modeling because they have a simple nervous system and exhibit well-defined behaviors. Studies using invertebrates have helped to understand neurosciences and the complexes associated with it. If Africa wants to catch up with the rest of the world in neuroscience research, it needs to employ this innovative cost-effective approach in its research. To improve invertebrate neuroscience within the Africa continent, the authors advocated the establishment of invertebrate research centers either at regional or national level across Africa. Finally, there is also a need to provide public funding to consolidate the gains that have been made by not-for-profit international organizations over the years.
  16. Balogun WG, Cobham AE, Amin A
    Metab Brain Dis, 2018 04;33(2):359-368.
    PMID: 28993966 DOI: 10.1007/s11011-017-0119-9
    The science of the brain and nervous system cuts across almost all aspects of human life and is one of the fastest growing scientific fields worldwide. This necessitates the demand for pragmatic investment by all nations to ensure improved education and quality of research in Neurosciences. Although obvious efforts are being made in advancing the field in developed societies, there is limited data addressing the state of neuroscience in sub-Saharan Africa. Here, we review the state of neuroscience development in Nigeria, Africa's most populous country and its largest economy, critically evaluating the history, the current situation and future projections. This review specifically addresses trends in clinical and basic neuroscience research and education. We conclude by highlighting potentially helpful strategies that will catalyse development in neuroscience education and research in Nigeria, among which are an increase in research funding, provision of tools and equipment for training and research, and upgrading of the infrastructure at hand.
  17. Afzal MR, Daoud EG, Cunnane R, Mulpuru SK, Koay A, Hussain A, et al.
    Heart Rhythm, 2018 06;15(6):841-846.
    PMID: 29427820 DOI: 10.1016/j.hrthm.2018.02.008
    BACKGROUND: Experience with retrieval of the Micra transcatheter pacing system (TPS) is limited because of its relatively newer technology. Although abandonment of the TPS at end of life is recommended, certain situations such as endovascular infection or device embolization warrant retrieval.

    OBJECTIVE: The purpose of this study was to report the worldwide experience with successful retrieval of the Micra TPS.

    METHODS: A list of all successful retrievals of the currently available leadless pacemakers (LPs) was obtained from the manufacturer of Micra TPS. Pertinent details of retrieval, such as indication, days postimplantation, equipment used, complications, and postretrieval management, were obtained from the database collected by the manufacturer. Other procedural details were obtained directly from the operators at each participating site.

    RESULTS: Data from the manufacturer consisted of 40 successful retrievals of the Micra TPS. Operators for 29 retrievals (73%) provided the consent and procedural details. Of the 29 retrievals, 11 patients underwent retrieval during the initial procedure (immediate retrieval); the other 18 patients underwent retrieval during a separate procedure (delayed retrieval). Median duration before delayed retrieval was 46 days (range 1-95 days). The most common reason for immediate retrieval was elevated pacing threshold after tether removal. The most common reasons for delayed retrieval included elevated pacing threshold at follow-up, endovascular infection, and need for transvenous device. Mean procedure duration was 63.11 ± 56 minutes. All retrievals involved snaring via a Micra TPS delivery catheter or steerable sheath. No serious complications occurred during the reported retrievals.

    CONCLUSION: Early retrieval of the Micra TPS is feasible and safe.

  18. Balogun WG, Cobham AE, Amin A, Seeni A
    Metab Brain Dis, 2018 10;33(5):1431-1441.
    PMID: 29797116 DOI: 10.1007/s11011-018-0250-2
    Africa is faced with an increasing underrepresentation of her research progress in many fields of science including neuroscience. This underrepresentation stems from the very low investments directed towards research by African governments as these are thought to be high-priced. Scientists and researchers within the continent are left to compete highly for the very limited research grants or choose to fund research from their personal purse. Therefore, presenting a need for all possible strategies to make science and research approaches more affordable in Africa. This paper presents one of such strategy, which advocates the use of invertebrate animal models for neuroscience research in place of the commonly used vertebrate models. Invertebrates are cheaper, more available and easy to handle options and their use is on the rise, even in the developed societies of the world. Here, we investigate the current state of invertebrate neuroscience research in Africa looking at countries and institutions conducting neuroscience research with invertebrates and their publication output. We discuss the factors which impede invertebrate neuroscience research in Africa like lack of research infrastructure and adequate expert scientists and conclude by suggesting solutions to these challenges.
  19. Teo, B.H., Safinaz, M.K., Mae-Lynn, C.B., Amin, A., Edward, R., Mushawiahti, M.
    Medicine & Health, 2018;13(2):175-179.
    MyJurnal
    It is rare for anterior chamber migration of an Ozurdex® implant from vitreous cavity, but it is seen more frequently in aphakic eyes or in pseudophakic cases with zonular dehiscense. We describe a case of a middle-aged gentleman who had persistent diabetic macular oedema not responding to anti-VEGF (vascular endothelium growth factor), who was treated with intravitreal Ozurdex® in his post vitrectomized eye and developed anterior migration of the implant to the anterior chamber. Anterior dislocation of an intravitreal implant of dexamethasone can be managed by repositioning it to the vitreous cavity or removing it through a corneal limbal incision. Ozurdex® is a friable implant, especially after a few weeks of implantation. Therefore, removal of the implant by grasping or aspiration may lead to its fracture or dispersion of the implant material. This is a report of a simple,fast and effective technique to remove a migrated Ozurdex® from the anterior chamber using a modified silicone tip.
Related Terms
Filters
Contact Us

Please provide feedback to Administrator (afdal@afpm.org.my)

External Links