Displaying publications 1 - 20 of 40 in total

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  1. Abd Samad H, Jaafar M, Othman R, Kawashita M, Abdul Razak NH
    Biomed Mater Eng, 2011;21(4):247-58.
    PMID: 22182792 DOI: 10.3233/BME-2011-0673
    In present study, a new composition of glass-ceramic was synthesized based on the Na2O-CaO-SiO2-P2O5 glass system. Heat treatment of glass powder was carried out in 2 stages: 600 °C as the nucleation temperature and different temperature on crystallization at 850, 950 and 1000 °C. The glass-ceramic heat-treated at 950 °C was selected as bioactive filler in commercial PMMA bone cement; (PALACOS® LV) due to its ability to form 2 high crystallization phases in comparison with 850 and 1000 °C. The results of this newly glass-ceramic filled PMMA bone cement at 0-16 wt% of filler loading were compared with those of hydroxyapatite (HA). The effect of different filler loading on the setting properties was evaluated. The peak temperature during the polymerization of bone cement decreased when the liquid to powder (L/P) ratio was reduced. The setting time, however, did not show any trend when filler loading was increased. In contrast, dough time was observed to decrease with increased filler loading. Apatite morphology was observed on the surface of the glass-ceramic and selected cement after bioactivity test.
    Matched MeSH terms: Bone Cements/chemistry*
  2. Abdul Wahab AH, Mohamad Azmi NA, Abdul Kadir MR, Md Saad AP
    Int J Artif Organs, 2022 Feb;45(2):200-206.
    PMID: 33645338 DOI: 10.1177/0391398821999391
    Glenoid conformity is one of the important aspects that could contribute to implant stability. However, the optimal conformity is still being debated among the researchers. Therefore, this study aims to analyze the stress distribution of the implant and cement in three types of conformity (conform, non-conform, and hybrid) in three load conditions (central, anterior, and posterior). Glenoid implant and cement were reconstructed using Solidwork software and a 3D model of scapula bone was done using MIMICS software. Constant load, 750 N, was applied at the central, anterior, and posterior region of the glenoid implant which represents average load for daily living activities for elder people, including, walking with a stick and standing up from a chair. The results showed that, during center load, an implant with dual conformity (hybrid) showed the best (Max Stress-3.93 MPa) and well-distributed stress as compared to other conformity (Non-conform-7.21 MPa, Conform-9.38 MPa). While, during eccentric load (anterior and posterior), high stress was located at the anterior and posterior region with respect to the load applied. Cement stress for non-conform and hybrid implant recorded less than 5 MPa, which indicates it had a very low risk to have cement microcracks, whilst, conform implant was exposed to microcrack of the cement. In conclusion, hybrid conformity showed a promising result that could compromise between conform and non-conform implant. However, further enhancement is required for hybrid implants when dealing with eccentric load (anterior and posterior).
    Matched MeSH terms: Bone Cements*
  3. Amer AAR, Abdullah MMAB, Liew YM, A Aziz IH, Wysłocki JJ, Tahir MFM, et al.
    Materials (Basel), 2021 Feb 26;14(5).
    PMID: 33652863 DOI: 10.3390/ma14051094
    The demand for durable, resistant, and high-strength structural material has led to the use of fibers as reinforcing elements. This paper presents an investigation into the inclusion of chopped steel wool fibers (CSWFs) in cement to form a high-flexural strength cementitious composite matrix (CCM). CSWFs were used as the primary reinforcement in CCM at increments of 0.5 wt%, from 0.5-6 wt%, with ratios of cement to sand of 1:1.5 and water to cement of 0.45. The inclusion of CSWFs resulted in an excellent optimization of the physicomechanical properties of the CCM, such as its density (2.302 g/cm3), compressive strength (61.452 MPa), and maximum flexural strength (10.64 MPa), all of which exceeded the performances of other reinforcement elements reported in the literature.
    Matched MeSH terms: Bone Cements
  4. Arif M, Sivananthan S, Choon DS
    J Orthop Surg (Hong Kong), 2004 Jun;12(1):25-30.
    PMID: 15237118
    To report the outcome of revised total hip arthroplasty procedures involving an anterior cortical window, extensive strut allografts, and an Exeter impaction graft.
    Matched MeSH terms: Bone Cements
  5. Ataollahi Oshkour A, Pramanik S, Shirazi SF, Mehrali M, Yau YH, Abu Osman NA
    ScientificWorldJournal, 2014;2014:616804.
    PMID: 25538954 DOI: 10.1155/2014/616804
    This study investigated the impact of calcium silicate (CS) content on composition, compressive mechanical properties, and hardness of CS cermets with Ti-55Ni and Ti-6Al-4V alloys sintered at 1200°C. The powder metallurgy route was exploited to prepare the cermets. New phases of materials of Ni16Ti6Si7, CaTiO3, and Ni31Si12 appeared in cermet of Ti-55Ni with CS and in cermet of Ti-6Al-4V with CS, the new phases Ti5Si3, Ti2O, and CaTiO3, which were emerged during sintering at different CS content (wt%). The minimum shrinkage and density were observed in both groups of cermets for the 50 and 100 wt% CS content, respectively. The cermets with 40 wt% of CS had minimum compressive Young's modulus. The minimum of compressive strength and strain percentage at maximum load were revealed in cermets with 50 and 40 wt% of CS with Ti-55Ni and Ti-6Al-4V cermets, respectively. The cermets with 80 and 90 wt% of CS showed more plasticity than the pure CS. It concluded that the composition and mechanical properties of sintered cermets of Ti-55Ni and Ti-6Al-4V with CS significantly depend on the CS content in raw cermet materials. Thus, the different mechanical properties of the cermets can be used as potential materials for different hard tissues replacements.
    Matched MeSH terms: Bone Cements/chemistry*
  6. Chai CS, Kho SS, Chan SK, Tee TT, Tie ST
    Clin Med (Lond), 2021 Jan;21(1):e114-e115.
    PMID: 33479093 DOI: 10.7861/clinmed.2020-0913
    Percutaneous vertebroplasty (PV) involves injection of polymethylmethacrylate bone cement into vertebral body for relief of pain and strengthening of bone in symptomatic vertebral compression fractures.Passage of bone cement into vertebral venous plexus and then into the lungs is a rare and serious complication of PV. The reported incidence up to 26%.We present an incidental finding of pulmonary cement embolism (PCE) after PV. A 68-year-old woman with history of PV 3 years previously for T11 osteoporotic fracture presented to us with cough for 3 weeks following choking on a fish bone.Chest X-ray showed left lower zone consolidation and a high-density opacity in a tubular branching pattern, corresponding to pulmonary arterial distribution. Contrasted computed tomography of the thorax showed segmental pulmonary cement embolism of both lungs and left lower lobe consolidation.She underwent bronchoscopy with findings of a purulent secretion from the left lower lobe. Her symptoms resolved after 2 weeks of antibiotics. She was managed conservatively for the PCE as she remained asymptomatic.This case highlights the need for a standard post-PV chest X-ray, as patients with cement embolisms can be completely asymptomatic. Measures to minimise the risk of pulmonary cement embolisms during PV need to be taken.
    Matched MeSH terms: Bone Cements/adverse effects
  7. Chan, C.K., Goh, J.H., Ng, W.M., Kwan, M.K., Merican, A.M., Soong, K.L.
    Malays Orthop J, 2010;4(2):40-43.
    MyJurnal
    A 20- year-old female student was involved in a motor vehicle accident. She sustained a severe friction injury to the left knee that resulted in considerable soft tissue and bone loss. There was also damage to the knee extensor mechanism, tibialis anterior muscle, femoral trochlea, the anterior half of the tibial plateau extending distally to the proximal tibia and skin. However, there was no crushing of the limb or resultant neurovascular deficit but cancellous bone and the remainder of the joint were exposed. Repeated surgical debridement was performed and was followed by covering of the soft tissue using a latissimus dorsi free flap and skin grafts. The bony defect was reconstituted with antibiotic bone cement to prevent flap adherence and shrinkage, enhance stability and prevent fracture. The cement was later removed at the time of arthrodesis at which time an ipsilateral double barrel vascularised fibular graft supplemented with autogenously cancellous bone and a ring fixator was used. Computer tomography confirmed union at three months post procedure. The fixator was then removed and a tibialis posterior transfer was performed.
    Matched MeSH terms: Bone Cements
  8. Che Nor Zarida Che Seman, Zamzuri Zakaria, Zunariah Buyong, Mohd Shukrimi Awang, Ahmad Razali Md Ralib @ Md Raghib
    MyJurnal
    A novel injectable calcium phosphate bone cement (osteopaste) has been
    developed. Its potential application in orthopaedics as a filler of bone defects has been
    studied. The biomaterial was composed of tetra-calcium phosphate (TTCP) and tricalcium
    phosphate (TCP) powder. The aim of the present study was to evaluate the
    healing process of osteopaste in rabbit tibia.(Copied from article).
    Matched MeSH terms: Bone Cements
  9. Chiu CK, Lisitha KA, Elias DM, Yong VW, Chan CYW, Kwan MK
    J Orthop Surg (Hong Kong), 2018 10 26;26(3):2309499018806700.
    PMID: 30352524 DOI: 10.1177/2309499018806700
    BACKGROUND: This prospective clinical-radiological study was conducted to determine whether the dynamic mobility stress radiographs can predict the postoperative vertebral height restoration, kyphosis correction, and cement volume injected after vertebroplasty.

    METHODS: Patients included had the diagnosis of significant back pain caused by osteoporotic vertebral compression fracture secondary to trivial injury. All the patients underwent routine preoperative sitting lateral spine radiograph, supine stress lateral spine radiograph, and supine anteroposterior spine radiograph. The radiological parameters recorded were anterior vertebral height (AVH), middle vertebral height (MVH), posterior vertebral height (PVH), MVH level below, wedge endplate angle (WEPA), and regional kyphotic angle (RKA). The supine stress versus sitting difference (SSD) for all the above parameters were calculated.

    RESULTS: A total of 28 patients (4 males; 24 females) with the mean age of 75.6 ± 7.7 years were recruited into this study. The mean cement volume injected was 5.5 ± 1.8 ml. There was no difference between supine stress and postoperative radiographs for AVH ( p = 0.507), PVH ( p = 0.913) and WEPA ( p = 0.379). The MVH ( p = 0.026) and RKA ( p = 0.005) were significantly less in the supine stress radiographs compared to postoperative radiographs. There was significant correlation ( p < 0.05) between supine stress and postoperative AVH, MVH, PVH, WEPA, and RKA. The SSD for AVH, PVH, WEPA, and RKA did not have significant correlation with the cement volume ( p > 0.05). Only the SSD-MVH had significant correlation with cement volume, but the correlation was weak ( r = 0.39, p = 0.04).

    CONCLUSIONS: Dynamic mobility stress radiographs can predict the postoperative vertebral height restoration and kyphosis correction after vertebroplasty for thoracolumbar osteoporotic fracture with intravertebral clefts. However, it did not reliably predict the amount of cement volume injected as it was affected by other factors.

    Matched MeSH terms: Bone Cements*
  10. Deshmukh RG, Thevarajan K, Kok CS, Sivapathasundaram N, George SV
    J Arthroplasty, 1998 Feb;13(2):197-9.
    PMID: 9526214
    Revision arthroplasty of the hip is often complicated by infection, bone loss, and perioperative fracture of the femur. A simple, inexpensive spacer that keeps tissue planes intact and prevents soft tissue contracture during the interoperative period of a 2-stage revision is described. This can provide intramedullary support to a fractured or weak femur and enable local antibiotic delivery, as well as permit limited mobilization of the patient. It can be easily fabricated during surgery using universally available materials and can be tailored for specific requirements. Such a spacer was used in 5 cases. The experience is presented, and the technique and pitfalls are discussed.
    Matched MeSH terms: Bone Cements*
  11. Hashim S, Chin LY, Krishnasamy S, Sthaneswar P, Raja Mokhtar RA
    J Cardiothorac Surg, 2015;10:32.
    PMID: 25890367 DOI: 10.1186/s13019-015-0230-0
    Recently a biocompatible bone adhesive was introduced in addition to the sternal wires to expedite sternal union and improve patient recovery. In this study we aim to objectively assess the biomarker of pain in patient who received the biocompatible bone adhesive.
    Matched MeSH terms: Bone Cements/therapeutic use*
  12. Jacobs E, Saralidze K, Roth AK, de Jong JJ, van den Bergh JP, Lataster A, et al.
    Biomaterials, 2016 Mar;82:60-70.
    PMID: 26751820 DOI: 10.1016/j.biomaterials.2015.12.024
    There are a number of drawbacks to incorporating large concentrations of barium sulfate (BaSO4) as the radiopacifier in PMMA-based bone cements for percutaneous vertebroplasty. These include adverse effects on injectability, viscosity profile, setting time, mechanical properties of the cement and bone resorption. We have synthesized a novel cement that is designed to address some of these drawbacks. Its powder includes PMMA microspheres in which gold particles are embedded and its monomer is the same as that used in commercial cements for vertebroplasty. In comparison to one such commercial cement brand, VertaPlex™, the new cement has longer doughing time, longer injection time, higher compressive strength, higher compressive modulus, and is superior in terms of cytotoxicity. For augmentation of fractured fresh-frozen cadaveric vertebral bodies (T6-L5) using simulated vertebroplasty, results for compressive strength and compressive stiffness of the construct and the percentage of the volume of the vertebral body filled by the cement were comparable for the two cements although the radiopacity of the new cement was significantly lower than that for VertaPlex™. The present results indicate that the new cement warrants further study.
    Matched MeSH terms: Bone Cements/chemical synthesis*
  13. Lee, K.H., Ng, A.B.Y., Tan, T.B., Mossinac, K., To, B.C. Se
    Malays Orthop J, 2008;2(2):11-15.
    MyJurnal
    Gentamicin, whether administered either intravenously, incorporated into bone cement or for local intra-operative irrigation, is a commonly used antibiotic in orthopaedic practice. The former two have been well studied, however the literature on the therapeutic efficacy and safety of gentamicin irrigation is sparse. The objective of this study was to assess systemic absorption of gentamicin irrigation in joint replacement surgery. This was a non-randomised, prospective study. Ninety-eight patients (group A) who underwent total joint replacement and 40 patients (group B) who underwent hemi-arthroplasty were treated traoperatively with gentamicin irrigation. Serum gentamicin levels were assayed at 4 hours and 24 hours post-surgery. Sixteen of 98 patients in group A (16%) and 12 out of 40 patients in group B (30%) were found to have serum gentamicin level above 2mcg/ml at 4 hours post-surgery. We conclude that intra-articular gentamicin irrigation is systemically absorbed at substantial levels.
    Matched MeSH terms: Bone Cements
  14. Lim, Chia Hua, Jacob, V.A., Premchandran, N.
    MyJurnal
    The present concepts in Total Hip Arthroplasty advocate mechanical cement interlock
    with trabecular bone utilising the third-generation cementing technique. However, the
    force generated can easily reach peak pressure of 122 kPa to 1500 kPa, leading to
    extrusion of cement through nutrient foramina into femoral cortex into nutrient vessels,
    henceforth the retrograde arteriovenogram. (Copied from article).
    Matched MeSH terms: Bone Cements
  15. Looi, Collin Seng-Kim
    MyJurnal
    Background: To assess the effect of cement vertebroplasty on the activity of daily living of elderly patients who have sustained a vertebral osteoporotic fracture.
    Patients and Methods: Seven patients with clinically significant and radiologically proven osteoporotic vertebral compression fractures suitable to be treated with percutaneous cement vertebroplasty were recruited. Evaluation was based on pre- and postprocedure activity by clinical documentation (including interview) and by a self-developed questionnaire (including quality of life).
    Results: Following the procedure, 54% of patients resumed their activities of daily living with minimal pain while 46% of patients were able to do so without any pain (p
    Matched MeSH terms: Bone Cements
  16. Low KL, Tan SH, Zein SH, Roether JA, Mouriño V, Boccaccini AR
    J Biomed Mater Res B Appl Biomater, 2010 Jul;94(1):273-86.
    PMID: 20336722 DOI: 10.1002/jbm.b.31619
    A major weakness of current orthopedic implant materials, for instance sintered hydroxyapatite (HA), is that they exist as a hardened form, requiring the surgeon to fit the surgical site around an implant to the desired shape. This can cause an increase in bone loss, trauma to the surrounding tissue, and longer surgical time. A convenient alternative to harden bone filling materials are injectable bone substitutes (IBS). In this article, recent progress in the development and application of calcium phosphate (CP)-based composites use as IBS is reviewed. CP materials have been used widely for bone replacement because of their similarity to the mineral component of bone. The main limitation of bulk CP materials is their brittle nature and poor mechanical properties. There is significant effort to reinforce or improve the mechanical properties and injectability of calcium phosphate cement (CPC) and this review resumes different alternatives presented in this specialized literature.
    Matched MeSH terms: Bone Cements/metabolism; Bone Cements/chemistry
  17. Mirzasadeghi A, Narayanan SS, Ng MH, Sanaei R, Cheng CH, Bajuri MY, et al.
    Biomed Mater Eng, 2014;24(6):2177-86.
    PMID: 25226916 DOI: 10.3233/BME-141029
    The application of bone substitutes and cements has a long standing history in augmenting fractures as a complement to routine fracture fixation techniques. Nevertheless, such use is almost always in conjunction with definite means of fracture fixation such as intramedullary pins or bone plates. The idea of using biomaterials as the primary fixation bears the possibility of simultaneous fixation and bone enhancement. Intramedullary recruitment of bone cements is suggested in this study to achieve this goal. However, as the method needs primary testings in animal models before human implementation, and since the degree of ambulation is not predictable in animals, this pilot study only evaluates the outcomes regarding the feasibility and safety of this method in the presence of primary bone fixators. A number of two sheep were used in this study. Tibial transverse osteotomies were performed in both animals followed by external skeletal fixation. The medullary canals, which have already been prepared by removing the marrow through proximal and distal drill holes, were then injected with calcium phosphate cement (CPC). The outcomes were evaluated postoperatively by standard survey radiographs, morphology, histology and biomechanical testings. Healing processes appeared uncomplicated until week four where one bone fracture recurred due to external fixator failure. The results showed 56% and 48% cortical thickening, compared to the opposite site, in the fracture site and proximal and distal diaphyses respectively. This bone augmentative effect resulted in 264% increase in bending strength of the fracture site and 148% increase of the same value in the adjacent areas of diaphyses. In conclusion, IMCO, using CPC in tibia of sheep, is safe and biocompatible with bone physiology and healing. It possibly can carry the osteopromotive effect of the CPCs to provide a sustained source of bone augmentation throughout the diaphysis. Although the results must be considered preliminary, this method has possible advantages over conventional methods of bone fixation at least in bones with compromised quality (i.e. osteoporosis and bone cysts), where rigid metal implants may jeopardize eggshell cortices.
    Matched MeSH terms: Bone Cements/therapeutic use*
  18. Mohamed-Haflah NH, Kassim Y, Zuchri I, Zulmi W
    Malays Orthop J, 2017 Mar;11(1):28-34.
    PMID: 28435571 MyJurnal DOI: 10.5704/MOJ.1703.013
    INTRODUCTION: The role of surgery in skeletal metastasis is to reduce morbidity and improve the quality of life in terminally ill patients. We report our experience with patients who underwent skeletal reconstructive surgery for metastatic bone tumour of the femur.

    MATERIALS AND METHODS: Twenty nine operations for skeletal metastasis of the femur performed in our centre between 2009 and 2015 were included in this study. We evaluated the choice of implant, complications, survival rate and functional outcome. Fourteen patients were still alive at the time of this report for assessment of functional outcome using Musculoskeletal Tumour Society (MSTS) form.

    RESULTS: Plating osteosynthesis with augmented-bone cement was the most common surgical procedure (17 patients) performed followed by arthroplasty (10 patients) and intramedullary nailing (2 patients) There were a total of five complications which were implant failures (2 patients), surgical site infection (2 patients), and site infection mortality (1 patient). The median survival rate was eight months. For the functional outcome, the mean MSTS score was 66%.

    CONCLUSION: Patients with skeletal metastasis may have prolonged survival and should undergo skeletal reconstruction to reduce morbidity and improve quality of life. The surgical construct should be stable and outlast the patient to avoid further surgery.

    Matched MeSH terms: Bone Cements
  19. Mohd Fuad D, Masbah O, Shahril Y, Jamari S, Norhamdan MY, Sahrim SH
    Med J Malaysia, 2006 Feb;61 Suppl A:27-9.
    PMID: 17042225
    Antibiotic-loaded bone cement has been used as prophylaxis against infection in total joint replacement surgery. Its effect on the mechanical strength of cement is a major concern as high dose of antibiotic was associated with a significant reduction in mechanical strength of bone cement. However, the cut-off antibiotic that weakens the mechanical strength of cement remains to be determined. This study was undertaken to observe the changes in the mechanical properties of bone cement with gradual increments of Cefuroxime antibiotic. Cefuroxime at different doses: 0, 1.5, 3.0 and 4.5gm were added to a packet of 40gm bone cement (Simplex P) and study samples were prepared by using third generation cementing technique. Mechanical impact, flexural and tensile strength were tested on each sample. Significant impact and tensile strength reduction were observed after addition of 4.5 gm of Cefuroxime. However, flexural strength was significantly reduced at a lower dose of 3.0 gm. The maximum dose of Cefuroxime to be safely added to 40mg Surgical Simplex P is 1.5gm when third generation cementing technique is used. Further study is needed to determine whether it is an effective dose as regards to microbiological parameters.
    Matched MeSH terms: Bone Cements/analysis*
  20. NUR FIKRIAH HASHIM, NURAQILAH MOHD ZAINAL, NURAIN JAMIL, NURUL NASUHA MOHD NOR, SURIANI MAT JUSOH
    MyJurnal
    Nowadays, Kenaf fiber is sustainably useful in marine structures and has become one of the materials that may be high in demand as it is light, biodegradable and environmental friendly. This study investigates the effect of fiber percentage on compressive strength of fiber reinforced concrete (FRC) and the relationship between compressive strength and time of FRC immersion in seawater. FRC concrete cubes were prepared using four different percentage of fiber (0%, 1.5%, 3.0% and 4.5%). These FRC were immersed in seawater for 7, 14 and 21 days for three consecutive weeks. Based on the experiment, it was found that there was improvement in compressive strength of FRC when compared to plain cement concrete. The results showedthat 3.0% of KF to cement matrix concrete determined the highest compressive strength of 205.43 Pa while 0% of KF fiber to cement concrete matrix (control specimen) showed the lowest compressive strength of 158.28 Pa. Also the addition of Kenaf fiber to cement concrete decreased the seawater absorption more than concrete with absolutely 0% of KF fiber to cement concrete (control specimen). In conclusion, the results did show significant improvement and a consistent trend on strength with the addition of FRC. This study also revealed that the percentage of water absorption was on the increase for 0, 7 and 14 days and become constant after day 21. This is due to manufacturing defects that occurred which block the water from entering the material and making the material absorb less water.
    Matched MeSH terms: Bone Cements
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