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Fulltext Posterolateral intertransverse lumbar arthrodesis in the New Zealand white rabbit model: the illustration of an alternative surgical approach

Zunariah, B., Zamzuri, Z., Che Nor Zarida, C.S., Rosnani, A.J.

International Medical Journal Malaysia, 2012;11(2):19-22.
MyJurnal

Introduction: The New Zealand White (NZW) rabbit model is commonly used for the research of
posterolateral intertransverse lumbar arthrodesis. The standard approach reported by many
researchers are a muscle splitting approach through the intermuscular plane between multifidus and longissimus muscles. Methods: In this research the fusion bed was exposed by retracting the three groups of paraspinal muscles (multifidus, longissimus and iliocostalis) medially. Results: This alternative method showed good exposure of the transverse processes and intertransverse membrane with less bleeding from the muscles observed. No death due to surgical complication was observed out of twenty-four rabbits operated. Conclusion: An easy and safe method for performing posterolateral intertransverse lumbar arthrodesis was demonstrated and recommended as an alternative approach for surgery on New Zealand White rabbits.

Matched MeSH terms: Research Personnel
Fulltext Improving perioperative pain management: a preintervention and postintervention study in 7 developing countries

Zaslansky R, Chapman CR, Baumbach P, Bytyqi A, Castro Lopes JM, Chetty S, et al.

Pain Rep, 2019 01 25;4(1):e705.
PMID: 30801045 DOI: 10.1097/PR9.0000000000000705

Introduction: The burden of untreated postoperative pain is high.
Objective: This study assessed feasibility of using quality improvement (QI) tools to improve management of perioperative pain in hospitals in multiple developing countries.
Methods: The International Pain Registry and Developing Countries working groups, from the International Association for the Study of Pain (IASP), sponsored the project and PAIN OUT, a QI and research network, coordinated it, and provided the research tools. The IASP published a call about the project on its website. Principal investigators (PIs) were responsible for implementing a preintervention and postintervention study in 1 to 2 surgical wards in their hospitals, and they were free to choose the QI intervention. Trained surveyors used standardized and validated web-based tools for collecting findings about perioperative pain management and patient reported outcomes (PROs). Four processes and PROs, independent of surgery type, assessed effectiveness of the interventions.
Results: Forty-three providers responded to the call; 13 applications were selected; and PIs from 8 hospitals, in 14 wards, in 7 countries, completed the study. Interventions focused on teaching providers about pain management. Processes improved in 35% and PROs in 37.5% of wards.
Conclusions: The project proved useful on multiple levels. It offered PIs a framework and tools to perform QI work and findings to present to colleagues and administration. Management practices and PROs improved on some wards. Interpretation of change proved complex, site-dependent, and related to multiple factors. PAIN OUT gained experience coordinating a multicentre, international QI project. The IASP promoted research, education, and QI work.

Matched MeSH terms: Research Personnel
Fulltext Husbands’ experience with their wives’ breast cancer: a qualitative study

Yusoff, N., Reiko Yap, K.M., Ahmad, A.

Malaysian Journal of Public Health Medicine, 2012;12(1):31-38.
MyJurnal

This study aims to explore the life experience of the husbands of women who survived breast cancer for more than five years following breast removal. Basic interpretative of qualitative methodology was applied in order to construct the phenomenon of breast cancer from the perspective of husbands. This approach allowed researchers to explore in-depth the experience of husbands in facing breast cancer of their wives. Four themes were identified. These are marital
challenges, pattern of life, supportive atmosphere and psychological defenses. Health strategies should direct the family member to the specific pathway in order to facilitate them towards the effective action of healthcare at their level. Evidence from this study is a direction for future research and health planning for better health policy.

Matched MeSH terms: Research Personnel
Fulltext Informed consent in clinical trials with reference to information disclosure to patient-subjects

Yuhanif Yusof, Anisah Che Ngah, Zaki Morad Mohamad Zaher

Int J Public Health Res, 2014;4(1):384-390.
MyJurnal

Introduction The aim of this study was to examine the aspect of information disclosure by doctor-investigator during the process of obtaining informed consent in clinical trials.
Methods This research employed a mixed-method data collection that is library research and interview. A qualitative methodology and analysis were used in an open-ended, face-to-face interviews with 17 patient-subjects. The interview questions were based on information that needed to be disclosed to patient-subjects during the process of obtaining informed consent. Each interview took place in Kajang Hospital and National Heart Institute and lasted 25-30 minutes. Interviews were conducted in Bahasa Melayu and English. The interviews were tape-recorded, and the main points from the interviews were jotted down to ensure that all information was adequately gathered. Interviewed occurred in Kajang Hospital and National Heart Institute. The participants were patients who had been referred to the Kajang Hospital and National Heart Institute. They were recruited (8 from Kajang Hospital and 9 from National Heart Institute) by their own doctors to participate in a study to evaluate the safety and effectiveness of the investigational stent after been diagnosed with coronary artery disease and also in a study to investigate drug for antidepressant. respectively.
Results The study revealed that doctor-investigators fail to disclose full information to patient-subjects. Instead, doctor-investigators only disclosed information which they thought were necessary for the patient-subjects to know. The study also showed that there were doctor-investigators who did not disclose information at all to the patient-subjects.
Conclusions This study implies that the aspect of information disclosure in the process of obtaining informed consent in clinical trials is rather poor and did not fulfill the criterion of good medical practice. A random monitoring task to be conducted by the research ethics commitees during the informed consent process is suggested.

Matched MeSH terms: Research Personnel
Trend of the research on construction and demolition waste management

Yuan H, Shen L

Waste Manag, 2011 Apr;31(4):670-9.
PMID: 21169008 DOI: 10.1016/j.wasman.2010.10.030

Research interests in addressing construction and demolition (C&D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C&D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibit an increasing research interest in C&D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C&D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C&D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C&D waste management research, and this is considered a major methodology for future research in the discipline. C&D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C&D waste management has emerged as a new challenging topic.

Matched MeSH terms: Research Personnel
Fulltext Social and communicative functions of informed consent forms in East Asia and beyond

Yoshizawa G, Sasongko TH, Ho CH, Kato K

Front Genet, 2017;8:99.
PMID: 28775738 DOI: 10.3389/fgene.2017.00099

The recent research and technology development in medical genomics has raised new issues that are profoundly different from those encountered in traditional clinical research for which informed consent was developed. Global initiatives for international collaboration and public participation in genomics research now face an increasing demand for new forms of informed consent which reflect local contexts. This article analyzes informed consent forms (ICFs) for genomic research formulated by four selected research programs and institutes in East Asia - the Medical Genome Science Program in Japan, Universiti Sains Malaysia Human Research Ethics Committee in Malaysia, and the Taiwan Biobank and the Taipei Medical University- Joint Institutional Review Board in Taiwan. The comparative text analysis highlights East Asian contexts as distinct from other regions by identifying communicative and social functions of consent forms. The communicative functions include re-contact options and offering interactive support for research participants, and setting opportunities for family or community engagement in the consent process. This implies that informed consent cannot be validated solely with the completion of a consent form at the initial stage of the research, and informed consent templates can facilitate interactions between researchers and participants through (even before and after) the research process. The social functions consist of informing participants of possible social risks that include genetic discrimination, sample and data sharing, and highlighting the role of ethics committees. Although international ethics harmonization and the subsequent coordination of consent forms may be necessary to maintain the quality and consistency of consent process for data-intensive international research, it is also worth paying more attention to the local values and different settings that exist where research participants are situated for research in medical genomics. More than simply tools to gain consent from research participants, ICFs function rather as a device of social communication between research communities and civic communities in liaison with intermediary agents like ethics committees, genetic counselors, and public biobanks and databases.

Matched MeSH terms: Research Personnel
Fulltext Risk factors of peripheral venous catheterization thrombophlebitis

Yoong, Wilkinson Jian Tan, Jo Wearn Yeap, Sharifah Sulaiha Syed Aznal

International e-Journal of Science, Medicine & Education, 2012;6(1):24-30.
MyJurnal

Background: Peripheral venous catheterisation is indispensable in modern practise of medicine. The indications of venous access should be weighed against the risk of complications, the commonest being thrombophlebitis. Thrombophlebitis causes patient discomfort and the need for new catheter insertion and risk of developing further widespread infections. Methodology: This observational study was conducted on adult patients admitted to the surgical and medical ward of a tertiary hospital in Negeri Sembilan Malaysia in 2011. Four researchers visited patients daily and examined for signs of thrombophlebitis; warmth, erythema, swelling, tenderness or a palpable venous cord. Risks factors that were studied in this research were patient/s age and gender, duration of catheterization, use of catheter for infusion, size of catheter, site of catheter insertion and types of infusate. Thrombophlebitis was graded using a scale adapted from Bhandari et al. (1979). Results: In total, 428 patients were recruited with an incidence rate of thrombophlebitis of 35.2%. Among those who developed thrombophlebitis, 65% had mild thrombophlebitis, 19% moderate and 8% severe thrombophlebitis. Results showed that female patients had a significant increased risk of developing thrombophlebitis. Also risk increased significantly with increased duration of catheterization and usage of the catheter for infusion. The age of a patient, types of infusate use, size of catheter and site of catheter insertion did not significantly influence the development of thrombophlebitis. Conclusion: The study showed that risk of developing thrombophlebitis is significantly increased among female patients, and also with increased duration of catheterization and use of the peripheral venous catheter for infusion. We recommended elective replacement of catheter every 72 hours and daily examination of catheters for signs of thrombophlebitis by a healthcare personnel.

Matched MeSH terms: Research Personnel
Fulltext Angular velocity and elevation angle: the proposed human model scalable tracking model using linear regression

Yong CY, Sudirman R, Chew KM

Sains Malaysiana, 2015;44(12):1661-1669.

A scalable tracking human model was proposed for recognizing human jogging and walking activities. The model aims to detect and track a particular subject by using wearable sensor. Data collected are in accelerometer readings in three axes and gyroscope readings in three axes. The development of proposed human model is based on the moderating effects on human movements. Two moderators were proposed as the moderating factors of human motion and they are angular velocity and elevation angle. Linear regression is used to investigate the relationship among inputs, moderators and outputs of the model. The result of this study showed that the angular velocity and elevation angle moderators are affecting the relation of research output. Acceleration in x-axis (Ax) and angular velocity in y-axis (Gy) are the two main components in directing
a motion. Classification between jogging and walking motions was done by measuring the magnitude of angular velocity and elevation angle. Jogging motion was classified and identified with larger angular velocity and elevation angle. The two proposed hypotheses were supported and proved by research output. The result is expected to be beneficial and able to assist researcher in investigating human motions.

Matched MeSH terms: Research Personnel
Fulltext Mind, body and cancer

Yip, C.H

JUMMEC, 2010;13(1):1-2.
MyJurnal

Many researchers studies have shown that stressful life events, from the death of a loved one to the loss of a job, are linked to an increase in certain health problems, particularly heart disease, diabetes, and hypertension. Many people assume that stress leads to cancer as well. Evidence for this, however, is not clear. However, the significance of mind-body interactions in medicine is now increasingly being recognised.(Copied from article.)

Matched MeSH terms: Research Personnel
Fulltext Effects of electromagnetic field (EMF) on histological changes and norepinephrine levels in the brains of adult male rats

Yap, Hui Cin, Asmah Hamid, Farah Wahida Ibrahim, Nor Fadilah Rajab, Yanti Rosli

Jurnal Sains Kesihatan Malaysia, 2016;14(1):55-61.
MyJurnal

The emergence of research about the biological effects of electromagnetic field (EMF) have growing concern among
researchers. The aim of this study was to investigate the effects on the brain of rats periodically exposed to 0.1 mT EMF.
Total 24 adult male Sprague Dawley rats were subdivided randomly to 4 groups: 2 control groups (C1 6 hours: 6 h/
day for 5 days; C2 20 hours: 20 h/day for 5 days) and 2 treatment groups which exposed to 0.1 mT EMF (T1 6 hours:
6 h/day for 5 days; T2 20 hours: 20 h/day for 5 days). A significant decrease in the pyramidal cell number was higher
as the exposure duration to EMF was extended (T1, p

Matched MeSH terms: Research Personnel
Fulltext The h-index in Elsevier’s Scopus as an indicator of research achievement for young Malaysian scientists

Yap, C.K.

Pertanika Journal of Science & Technology, 2012;20(2):197-203.
MyJurnal

If we were given a questionnaire of “How do we measure a researcher as a true scientist? with optional answers like (a) Having a good number of publications, (b) having attending numerous conferences, (c) with a high popularity as always appeared in mass media, and (d) good international networking and good public relations. Options (c) and (d) always come later after option (a) has been achieved, while option (b) can be simply achieved or abstract be accepted for presentation in any conference. Hitherto, publishing in any peer-reviewed journals carry a certain quality since they are highly subjected to peer review evaluation before the paper can be accepted for publication in a journal. Needless to say, those constructive comments given by the reviewers are very crucial in shaping our scientific understanding in our subject area rather than rejection experience (Yap, 2009). Having said so, option (a) will definitely be the best answer. The fact is that option (a) should not be argued whatsoever as the best answer [since publications speaks louder than anything else] and options (a), (b) and (c) are supplementary criteria to option (a) but they are not as vital as option (a). When we are asked ‘What is your scientific research performance or research output?’, the answer could always be ‘Having a good number of publications.’ Then, the next question forwarded is that ‘What is the quality and impact of your published papers to the scientific community?’ Of course, good and high impact factor journals always accept papers with high novelty in the subject area. Therefore, papers published in good journals are always highly cited and subsequently resulting in high impact (or citations) of the research done to the scientific community. However, the last question is sometimes very subjective and difficult to answer until h-index is introduced and discussed among the researchers. This paper aimed to discuss the h-index based on Elsevier’s Scopus database as an indicator of research achievement for young Malaysian scientists.

Matched MeSH terms: Research Personnel
Plagiarism in publications using the unpublished raw data of archived research

Yahaghi J, Beddu SB, Muda ZC

Sci Eng Ethics, 2017 04;23(2):635-636.
PMID: 27432400 DOI: 10.1007/s11948-016-9807-9

It is obligatory to educate student researchers before they start their work by teaching them about the various types of plagiarism and how to avoid them. It is also vital that research supervisors take into account the sources of data that are explored in their students' manuscripts. This article tries to draw the reader's attention to the importance of avoiding all types of plagiarism in their research.

Matched MeSH terms: Research Personnel/ethics
Fulltext Impact of religiosity on purchase intentions towards counterfeit products: investigating the mediating role of attitude and moderating role of hedonic benefits

Yaakop AY, Hafeez HM, Faisal MM, Munir M, Ali M

Heliyon, 2021 Feb;7(2):e06026.
PMID: 33644436 DOI: 10.1016/j.heliyon.2021.e06026

This study was aimed at exploring the impact of religiosity on purchase intention towards counterfeit products by investigating the mediating role of consumer attitude. This study investigated religiosity as an independent variable, attitude towards counterfeit as a mediator while predicting the purchase intentions of the consumers. A self-administered questionnaire using a five-point Likert scale was used to collect data from the sample of 420 respondents who were from twin cities (Rawalpindi and Islamabad) of Pakistan. Structural equation modeling technique was used to achieve the set objectives. The results reveal a statistically significant effect of religiosity along with the significant mediating role of consumer attitude and the significant moderating role of hedonic benefits while predicting the purchase intentions of the consumers. This study also provides important insights for the researchers and the practitioners.

Matched MeSH terms: Research Personnel
Fulltext Lichenoid Lesion And Oral Squamous Cell Carcinoma Of The Tongue

Yaacob, H.B., Ngeow, W.C., Tan, P.L., Zainal Arif, A.R.

Ann Dent, 2002;9(1):-.
MyJurnal

The controversy on malignant transformation of oral lichen planus has always intrigued researchers. We present a case of lichenoid lesion and squamous cell carcinoma of the tongue, occurring in a middle aged Indian lady. The diagnosis and timing of these lesions is discussed.

Matched MeSH terms: Research Personnel
Fulltext Cost of type 2 diabetes mellitus in selected developing countries

Wan Norlida Ibrahim, Syed Aljunid, Aniza Ismail

Malaysian Journal of Public Health Medicine, 2010;10(2):68-71.
MyJurnal

Increasing prevalence of chronic diseases is a major contributor for rapid rise in healthcare cost in developing countries since the last decade. It was estimated that around 54% of deaths in developing countries are due to chronic non-communicable diseases which is predicted to rise by 65% by 2030. Diabetes mellitus is among the most prevalent chronic diseases suffered by more than 180 million people worldwide. By 2030 it is estimated that around 400 million people in the world will be afflicted with diabetes. Annual deaths attributable to diabetes are probably as high as 3 million with more than 80% occur in developing countries. India, China and Indonesia are three countries in the Asian region with most number of people with diabetes. The total number of cases in these three countries is expected to increase more than double from 61 million in 2000 to 163 million in 2030. China and India will suffer cumulative GDP loss of 13.8% and 16.7% respectively, over the next ten year period. Assessing economic burden of diabetes is a challenging task for researchers because identification of direct and indirect cost of the disease is often complex since patients with diabetes also suffers from other complications and co-morbidities. In conclusion, the heavy economic burden of diabetes pose major challenges to health policy makers in developing countries to assess the current approach in managing this chronic disease. Serious efforts should be made on focusing and up-scaling activities on health promotion and prevention of diabetes so that to provide a more cost-effective solution to this condition with huge and increasing economic loss.

Matched MeSH terms: Research Personnel
Fulltext Random sampling and allocation using SPSS

Wan Nor Arifin

Education in Medicine Journal, 2012;4(1):129-143.
MyJurnal

Among most important aspects in conducting a clinical trial are random sampling and allocation of subjects. The processes could be easier if done with familiar software used for data entry and analysis instead of relying on other programs or methods. The objective of this article is to demonstrate random sampling and allocation using SPSS in step-by-step manners using examples most relevant to clinicians as well as researchers in health sciences.

Matched MeSH terms: Research Personnel
Fulltext Introduction to sample size calculation

Wan Nor Arifin

Education in Medicine Journal, 2013;5(2):89-96.
MyJurnal

One of the most common reasons why researchers seek help from statistician is sample size calculation. However despite the common believe that it only involves formula and calculation, researchers often ignore other aspects of research design that leads to proper sample size calculation. In this article, the author outlines basic steps toward sample size calculation. The author also introduces the logic behind sample size calculation for single mean and single proportion in simplified and less intimidating forms to those not statistically inclined.

Matched MeSH terms: Research Personnel
Application of loglinear models in estimating wet category in monthly rainfall

Wahidah Sanusi, Kamarulzaman Ibrahim

Sains Malaysiana, 2012;41:1345-1353.

Climate changes have become serious issues that have been widely discussed by researchers. One of the issues concerns with the study in changes of rainfall patterns. Changes in rainfall patterns affect the dryness and wetness conditions of a region. In this study, the three-dimensional loglinear model was used to fit the observed frequencies and to model the expected frequencies of wet class transition on eight rainfall stations in Peninsular Malaysia. The expected frequency values could be employed to determine the odds value of wet classes of each station. Further, the odds values were used to estimate the wet class of the following month if the wet class of the previous month and current month were identified. The wet classification based on SPI index (Standardized Precipitation Index). For station that was analyzed, there was no difference found were between estimated and observed wet classes. It was concluded that the loglinear models can be used to estimate the wetness classes through the estimates of odds values.

Matched MeSH terms: Research Personnel
Women in Computational Chemistry

Wahab HA, Amaro RE, Cournia Z

J Chem Inf Model, 2018 11 26;58(11):2175-2177.
PMID: 30277769 DOI: 10.1021/acs.jcim.8b00642
Matched MeSH terms: Research Personnel/organization & administration
Experiments and rights

Vollrath J

Bioethics, 1989 Apr;3(2):93-105.
PMID: 11649247 DOI: 10.1111/j.1467-8519.1989.tb00331.x
Matched MeSH terms: Research Personnel*

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