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  1. Fulltext The effects of virgin coconut oil on postmenopausal osteoporotic bone: analyses on osteoblastogenesis and antioxidant genes. [Tindakan minyak kelapa dara terhadap tulang osteoporosis pascamenopaus: analisis gen osteoblastogenesis dan antioksidan]
    Shidqiyyah Abdul-Hamid, Norliza Muhammad, Isa Naina Mohamed
    Sains Malaysiana, 2016;45(12):1815-1822.
    Postmenopausal osteoporosis is one of the main health problems in aging women. It was due to several factors including oxidative stress, which can be controlled through intake of antioxidants from food sources. Virgin coconut oil (VCO) is one of the natural product rich in antioxidants and has been proven to protect osteoporotic bone. This study was conducted to gain in-depth understanding on virgin coconut oil’s activity on osteoporosis at molecular level. Thirty two female Sprague-Dawley rats were divided into four groups, namely Sham operated group, ovariectomized control group (Ovx+Ctrl), ovariectomized with VCO treatment (Ovx+VCO), and ovariectomized with estrogen treatment (Ovx+E). All treatments were administered orally for ten weeks. Bone samples were obtained to examine changes on expression of superoxide dismutase (SOD), glutathione peroxidase (GPX), osteocalcin and runt-related transcription factor 2 (Runx2) genes. The results indicated that rats receiving VCO treatment had experienced significant increments in SOD, GPX and osteocalcin gene expressions compared to the ovariectomized control group, besides the gene expressions of Runx2 which also showed an increment pattern. In conclusion, VCO helps to protect bone in osteoporotic rat model by increasing the expressions of antioxidant genes and genes which increase the osteoblast acitivities.
    Keywords: Osteoporosis; ovariectomized rat model; postmenopausal; virgin coconut oil
    Matched MeSH terms: Malaysia
  2. Fulltext Landslide factors and susceptibility mapping on natural and artificial slopes in Kundasang, Sabah
    Sharir K, Roslee R, Lee KE, Simon N
    Sains Malaysiana, 2017;46:1521-1540.
    This study was carried out on the hilly topographic area in Kundasang, Sabah. This area is known to be extremely prone to landslides that occurred either naturally or by human interference to natural slopes. Aerial photographs interpretation was conducted in order to identify landslide distributions across three assessment years (2012, 2009 and 1984). These datasets were classified into two landslides groups based on their occurrences; natural and artificial. A total of 362 naturally occurring landslides were identified and another 133 are artificial slope landslides. Physical parameters which include lithology, slope angle, slope aspect and soil series were analyzed with each landslide group to examine the different influence of these parameters on each of the group. From the analysis, the landslide density for the natural landslide group shows that more than 35° slope angle and slope aspect facing east and southwest are prone to landslides. In terms of geological materials, high landslide density is recorded in the phyllite, shale, siltstone and sandstone lithologies group and the Pinosuk, Kepayan and Trusmadi soil series. In contrast, for the artificial
    slope landslide, high landslide density is observed in the 25°-35° slope angle and similar density in every slope aspect classes. The geological materials however have similar landslide density across their factors’ classes. The landslide density technique was also used to generate the landslide susceptibility maps for both landslide conditions. Validation of the maps shows acceptable accuracy of 71% and 74%, respectively, for both natural and artificial slope landslide susceptibility maps and this shows that these maps can be used for future land use planning.
    Matched MeSH terms: Malaysia
  3. Fulltext Relationship between patient factors and specific learning needs of women on breast cancer
    Raja Lexshimi R, Siti Mariam B, Rohaizak M, Subahan M, Nabishah M
    Malaysian Journal of Public Health Medicine, 2017;17(1):14-23.
    The type of specific learning needs of women with breast cancer using the Information Needs Questionnaire (INQ) had been identified prior to developing a breast cancer education package. It is also important to determine the types of patient factors such as demographic and clinical factors that influence women’s specific learning needs on breast cancer. This study thus reports the findings on what type of patient factors influence women’s specific learning needs related to the types of INQ. A total of 140 women with breast cancer who sought treatment at Universiti Kebangsaan Malaysia Medical Centre participated in this cross sectional study. Age showed a significant relationship with specific learning needs on sexual attractiveness (p=0.001) and self-care (p=0.048). Duration of illness was related to information on spread of breast cancer (p=0.040) and self-care (p=0.047). Education level showed a significant relationship with cure (p=0.001), sexual attractiveness (p=0.007) and spread of breast cancer (p=0.003). Occupation showed a significant relationship with specific learning needs on sexual attractiveness (p=0.005), chemotherapy (p=0.043), radiotherapy (p=0.039) and hormonal therapy (p=0.043). On treatment received, a significant relationship was noted with sexual attractiveness (p=0.009), radiotherapy (p=0.029), hormonal therapy (p=0.038) and targeted therapy (p=0.047). Ethnicity and Marital status showed no significant relationship with all the specific learning needs. Findings of this study concluded that certain patient factors had significant relationship with certain specific learning needs. All the patient factors studied and their influence on the specific learning needs were taken into consideration prior to developing the breast cancer education package.
    Matched MeSH terms: Malaysia
  4. Fulltext Dengue Infection Complicated by Hemophagocytic Lymphohistiocytosis: Experiences From 180 Patients With Severe Dengue
    Kan FK, Tan CC, Von Bahr Greenwood T, Khalid KE, Supramaniam P, Hed Myrberg I, et al.
    Clin Infect Dis, 2020 05 23;70(11):2247-2255.
    PMID: 31188423 DOI: 10.1093/cid/ciz499
    BACKGROUND: Globally, ~500 000 people with severe dengue (SD) require hospitalization yearly; ~12 500 (2.5%) die. Secondary hemophagocytic lymphohistiocytosis (sHLH) is a potentially fatal hyperinflammatory condition for which HLH-directed therapy (as etoposide and dexamethasone) can be life-saving. Prompted by the high mortality in SD and the increasing awareness that patients with SD may develop sHLH, our objectives were to (1) determine the frequency of dengue-HLH in SD, (2) describe clinical features of dengue-HLH, (3) assess mortality rate in SD and dengue-HLH, and (4) identify mortality-associated risk factors in SD.

    METHODS: A 5-year retrospective single-center study in all adult patients with SD admitted to a tertiary intensive care unit in Malaysia.

    RESULTS: Thirty-nine of 180 (22%) patients with SD died. Twenty-one of 180 (12%) had HLH defined as an HLH probability ≥70% according to histo score (HScore); 9 (43%) died. Similarly, 12 of 31 (39%) fulfilling ≥4 and 7 of 9 (78%) fulfilling ≥5 HLH-2004 diagnostic criteria died. Peak values of aspartate aminotransferase (AST), alanine aminotransferase, lactate dehydrogenase, and creatinine correlated to fatality (odds ratios [ORs], 2.9, 3.4, 5.8, and 31.9; all P < .0001), as did peak ferritin (OR, 2.5; P = .0028), nadir platelets (OR, 1.9; P = .00068), hepatomegaly (OR, 2.9; P = .012), and increasing age (OR, 1.2; P = .0043). Multivariable logistic regression revealed peak AST (OR, 2.8; P = .0019), peak creatinine (OR, 7.3; P = .0065), and SOFA (Sequential Organ Failure Assessment) score (OR, 1.4; P = .0051) as independent risk factors of death.

    CONCLUSIONS: Be observant of dengue-HLH due to its high mortality. A prospective study is suggested on prompt HLH-directed therapy in SD patients with hyperinflammation and evolving multiorgan failure at risk of developing dengue-HLH.

    Matched MeSH terms: Malaysia
  5. Drivers of food waste generation: Case study of island-based hotels in Langkawi, Malaysia
    Kasavan S, Mohamed AF, Abdul Halim S
    Waste Manag, 2019 May 15;91:72-79.
    PMID: 31203944 DOI: 10.1016/j.wasman.2019.04.055
    Food waste (FW) generation from hotel operations have a significant negative impact on the environment, society and economy. Hence, the urgent need to introduce sustainable food management to reduce both FW and operational costs in hotels. The aim of this paper is to identify the drivers of FW generation and barriers to sustainable food waste management (SFWM) in island based hotels. The data were collected using in-depth interview coupled with the observations conducted at 23 selected hoteliers in Langkawi Island, Malaysia. Based on the analysis, using qualitative content analysis (QCA), eight FW drivers were identified and the drivers were classified into three categories of factors, mainly internal, external and intermediate influence. There are four FW drivers identified as internal factors that influenced the implementation of food waste management namely (1) poor hotel management and policies, (2) lack of skills in food preparation, (3) lack of facilities and FW technology and (4) non-implementation of waste audit and waste separation. For external factors, there are two FW drivers, including (5) unsustainable food consumption patterns of the customers and (6) risk of food ingredients spoilage. As for intermediate factors, two FW drivers were identified, which are (7) ineffective communication and (8) inadequate education and awareness. Findings from this study contribute towards a better understanding on the complexity of FW issues, particularly for island-based hotel sector. It was also suggested that a holistic approach with multi-stakeholders is crucial to reduce food wastage towards achieving SFWM.
    Matched MeSH terms: Malaysia
  6. The Patient's Charter - Validating actual services provided to the outpatient
    Khoo CM, Lim YL, Abdul H, Zaharudin R, Sharipah A, Azirawati J, et al.
    JUMMEC, 1997;2:107-110.
    The Patient's Charter tells about the rights and standard of service a patient can expect. However, little information is available to gauge the reality of the charter in real practice. This survey was performed to determine the validity of the charter to the services provided and to identify areas of improvement if the charter is to be revised. A questionnaire-based survey was used to seek information from 196 patients who attended the Outpatient Department in Banting District Hospital over a period of four days. The overall waiting time for registration, to be seen by a doctor and for medication were 17.4 ± 2.0 minutes, 25.3 ± 2.6 minutes and 15.8 ± 1.3 minutes respectively. The overall waiting time for the whole consultation was 61.4 ± 4.9 minutes. Only 30.8% respondents knew about the Patient's Charter. The Patient's Charter appears to be valid for the actual services provided. There have to be measures to increase the awareness of the charter to the public perhaps via pamphlets and to provide a multi-linguistic charter.
    Matched MeSH terms: Malaysia
  7. Amlodipine affects plasma angiotensinogen level: indirect evidence
    Rosnah I, Lam SK, Chua CT
    JUMMEC, 1997;2:31-34.
    Matched MeSH terms: Malaysia
  8. The yield of laboratory investigations for infective agents - a pilot study findings on foreign workers
    Anuar Zaini MZ, the Pilot Immigrant Health ST
    JUMMEC, 1998;3:61-62.
    A total of 245 foreign workers was screened for various microbial and parasitic infections, as part of the pilot study on the health problems of foreign workers. The sample comprising of Indonesian and Bangladeshi workers, was selected on a non-probability basis from two sources, i.e. University Hospital and a private sector. This investigation revealed substantive number of workers with positive cases to some of the microbial and parasitic infections. KEYWORDS: Pilot study, infective agents, foreign workers
    Matched MeSH terms: Malaysia
  9. Biological activities of dengue virus on murine macrophages
    Rajamani L, Nadia A, Shamala D
    JUMMEC, 1997;2:11-17.
    Matched MeSH terms: Malaysia
  10. Dengue 2 (New Guinea C strain) virus infection induces apoptosis
    Norazizah S, Sazaly AB
    JUMMEC, 1997;2:19-21.
    Matched MeSH terms: Malaysia
  11. Effect of gestational age on gentamicin pharmacokinetic parameters in the newborn
    Farizaturradiah O, Mohamed Z, Sim SM, Lim CT
    JUMMEC, 1997;2:35-38.
    Matched MeSH terms: Malaysia
  12. Teaching attitudes among teachers at the Faculty of Medicine, University of Malaya
    Jakiyah D, Azhary JMK, Mazkiah B, Mohd Hashim I, El-Sabban F
    JUMMEC, 1999;4:51-57.
    This paper involves the obtained results of an "Elective Program" project which was carried out by Phase I Medical Students of the 1998-1999 academic year at the Faculty of Medicine (FOM), University of Malaya (UM). A questionnaire was designed to survey the attitudes of teachers at FOM-UM, the subject of choice of a 4-student group who were supervised by a faculty member. Students obtained a list of faculty members (teachers) of all academic departments from the Dean's Office and rehearsed their interviewing skills prior to collecting the data of the questionnaire, within a 1-week period. Respondents were 146 out of 275 in total (53%), which included all academic ranks and clinical and non-clinical teachers. Results showed that respondents were well qualified, have enough teaching experience and teach in a variety of forms. All teachers liked to teach and were motivated; however, 15% felt unhappy about their teaching and 6% did not think that their teaching was effective. The nlajority (96%) of teachers liked their teaching to be evaluated and many revealed several means to assist and 111otivate students. Teachers felt that there was room for improvenlent in the aspect of student-teacher interactions. Results of this project revealed that FOM-UM is well endowed by qualified, motivated and caring teachers who wish for better interactions with their students. I
    Matched MeSH terms: Malaysia
  13. Fulltext Setting up a pain clinic for cancer pain relief - the Cancer Pain Clinic
    Delilkan AE
    JUMMEC, 1999;4(2):65-66.
    Matched MeSH terms: Malaysia
  14. Oral health problems among foreign workers
    Ishak AR
    JUMMEC, 2002;7:46-51.
    About 27% of the eligible respondents reported having experienced some form of dental problems in the preceding one year prior to the interview. Female respondents (57.1%) were more likely to have encountered a dental problem as compared to male respondents (22.6%). Of the various nationalities, the Thais (60.7%) and the Pakistanis were the most and least likely respectively to have encountered a dental problem in the preceding one year. This pattern among the Thais was consistent for both the male (48.4%) and female (70.6%) population. Toothache (85.0%) was reportedly the most prevalent dental problems encountered regardless of gender and nationality, followed by sensitivity to hot and cold drinks (34.4%). About 1 in 4 subjects who had dental problem reported having bleeding gums. About 1 in 4 subjects who had dental problems had consulted the doctor or dentists regarding their problem and one more than one-half had self-medicated. Overall the majority (84.4%) of the respondents have never visited the dentists in Malaysia. Lack of perceived need was cited as the main reason for this.
    Matched MeSH terms: Malaysia
  15. Early fluid resuscitation in the management of major burns: ten years experience in Tabuk, Saudi Arabia
    Rahoma AH
    JUMMEC, 2002;7:127-131.
    During the period from January 1992 up to the end of July 2001, the Burns Unit in King Khalid C Hospital treated 1735 cases of burns. The burns cases were of varying causes, age groups, degree, depth and extent. The formula used in lTeating these burns patients was a modification of Parkland fonnula. The fluid used was Ringer lactate solution. This fluid was administered for the first 3 days post burn until the general condilion of the palient was sfabilized. Early oral intake was encouraged in aU patients and was started as early as the second or the third day. Colloids were given by the end of the third or even the fourth day and according to the individual patients' needs. The results of this treatment regime significantly avoided renal complications and ensured patient rehydration. KEYWORDS; Major burns, fluids resuscitation
    Matched MeSH terms: Malaysia
  16. Emerging and re-emerging diseases: The migrant factor. [Abstract]
    Khairul Anuar A
    JUMMEC, 2002;7:14-14.
    Many nation states, including Malaysia are undergoing development and modernization while modernization brings tremendous achievements related to social and economic wellbeing, on the other hand, it also brings along with it the various untoward effects on the nation. One of the main factors which have an impact on modernization seems to be the rapid changes in the demographic pattern. In the initial stage of modernization, mass migration of rural populations to the urban areas, has been on going in Malaysia since the seventies. In the early nineties, the robust economic development in Malaysia necessitated the import of foreign labour from the neighbouring countries in order to provide cheap labour in the labour intensive industries. This demographic changes, internal and foreign migration, parallels the economic progress of the host countries. According to the latest report from the Immigration Department, there are more than 1.2 million registered foreign workers (up to January 1998) in Malaysia. This figure may exceed 2 million if we take into consideration the illegal immigrants and this is a big proportion (about 10%) of foreign workers in which has Malaysia's population of approxiamtely 20 million. The presence of such a big number of foreign workers during less than a decade is not merely an immigration issue, but it is a major concern for the nation especially with respect to health care, housing and education. As the immigrant community is highly dynamic, the emerging and re-emerging infectious diseases are a great concern for Malaysia especially in formulating health policies for Malaysia currently and in the future.
    Matched MeSH terms: Malaysia
  17. Pre-employment screening & monitoring of the health of foreign workers
    Khairul Anuar A, Nooriah MS
    JUMMEC, 2002;7:82-84.
    Matched MeSH terms: Malaysia
  18. Small forms of Blastocystis hominis
    Rajah S, Suresh K, Vennila GD, Khairul Anuar A, Saminathan R
    JUMMEC, 2002;7:77-79.
    Matched MeSH terms: Malaysia
  19. Fulltext Thismiadomei and T.terengganuensis (Thismiaceae), two new species, and T.javanica, a new record from Terengganu, Peninsular Malaysia
    Yunoh SM, Nikong D
    PhytoKeys, 2019;124:123-137.
    PMID: 31274980 DOI: 10.3897/phytokeys.124.34728
    Two new species of the mycoheterotrophic genus Thismia Griff. (Thismiaceae), Thismiadomei Siti-Munirah and T.terengganuensis Siti-Munirah from Peninsular Malaysia, are described and illustrated. Thismiadomei, characterized by its perianth lobes that are upright and curve inward, but are imperfectly connate, falls within sectionOdoardoa. Thismiaterengganuensis is characterized by its mitre with three appendages on its apex, so falls within sectionGeomitra. Both new species are unique and totally different from other described species, T.domei by the trichomes on its outer perianth tube surface and T.terengganuensis by its mitre with slender appendages. Thismiajavanica J.J.Sm, also from Terengganu, is a new record for Peninsular Malaysia.
    Matched MeSH terms: Malaysia
  20. Analisis prestasi nutrien pengkomposan sisa industri sawit bagi skala industri dalam tempoh tiga tahun
    Asis T, Zahrim AY, Assis K
    Sains Malaysiana, 2017;46:1201-1210.
    Pengkomposan tandan buah kosong (EFB) dan sisa efluen kilang (POME) merupakan pendekatan lestari bagi menukarkan EFB dan POME kepada baja kompos. Pengkomposan adalah satu proses biologi yang memerlukan pengawalan yang optimum agar nutrien yang terhasil adalah tinggi dan stabil. Cabaran utama yang dihadapi oleh industri kompos ialah untuk menghasilkan kompos yang bernutrien tinggi dan stabil. Objektif kajian ini ialah untuk menganalisis prestasi jangka panjang bagi loji kompos terpilih melalui kandungan nutrien kompos yang dihasilkan. Penyelidikan ini mengkaji prestasi tiga tahun bagi empat loji kompos di Malaysia iaitu loji kompos Merotai, loji kompos Binuang, loji kompos Tanah Merah dan loji kompos Elphil. Prestasi kandungan nutrien yang diambil kira termasuklah nitrogen, kalium, nisbah karbon kepada nitrogen, kandungan kelembapan dan agregat kompos. Sebanyak 1,465 set data nutrien dianalisis secara deskriptif. Secara keseluruhannya, prestasi kandungan nutrien kesemua loji kompos yang dikaji berjaya memenuhi keperluan minimum industri sawit. Namun terdapat kes kompos yang dihasilkan mengandungi nutrien kalium yang tidak mencapai keperluan minimum industri dan kandungan kelembapan kompos yang tinggi. Kesimpulannya, masih terdapat ruang untuk penambahbaikan dalam proses pengkomposan agar kompos yang dihasilkan mengandungi nutrien yang stabil dan memenuhi keperluan minimum industri
    Matched MeSH terms: Malaysia
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