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  1. Li Y, Udi UJ, Yussof MM, Tan X
    Rev Sci Instrum, 2024 Mar 01;95(3).
    PMID: 38535485 DOI: 10.1063/5.0186377
    The stayed-cable is an important component of cable-stayed bridges, with cable force being a focal point during construction and bridge operation. The advancement of camera and image processing technology has facilitated the integration of computer vision technology in structural inspection and monitoring. This paper focuses on enhancing cable force measurement methods and addressing the limitations of traditional testing techniques by conducting experimental research on cable force estimation using video recording. The proposed approach involves capturing video footage of the target on the cable with a smartphone. Subsequently, a combination of techniques such as the background subtraction method, image morphology processing, and Hough transform image processing technology are employed to detect the precise center coordinates and ultimately obtain the accurate displacement-time curve of the cable's vibration. In addition, the graphic Circularity Coefficient (CC) has been introduced to assess its effectiveness in post-motion-blur image processing for circular targets. The fundamental frequency of the cable is determined by the fast Fourier transformation, and the relationship between the cable force and the fundamental frequency is used to estimate the cable force. The experimental results are compared with data from accelerometers and force gauges, demonstrating that the frequency measurement error is below 1.2% and the cable force test error is less than 3%. In the process of acquiring the cable's fundamental frequency, the test directly employs the pixel as the displacement unit, eliminating the need for image calibration. The innovative use of the CC in processing motion-blurred targets ensured accurate recognition of target coordinates. The experimental findings highlight the method's simplicity, speed, and accuracy.
  2. Law NL, Tan VC, Lim TH, Nurul Rosli A
    PMID: 38371721 DOI: 10.51866/cr.438
    Orbital cellulitis is an extremely rare but potentially lethal condition in neonates. The clinical presentation of neonatal orbital cellulitis can be non-specific, and minimal signs of periorbital inflammation may go unrecognised by inexperienced parents or primary care medical personnel, leading to delayed treatment. Herein, we present a case series describing ophthalmia neonatorum complicated with neonatal orbital cellulitis owing to delayed treatment. The clinical presentation, management and outcomes are described. One neonate had orbital cellulitis, while the other had impending orbital cellulitis, with both cases resulting from delayed treatment of ophthalmia neonatorum. Both neonates were hospitalised for systemic antibiotic treatment and fully recovered with good outcomes. Timely identification and treatment of ophthalmia neonatorum are critical to mitigate potential severe sequelae, such as neonatal orbital cellulitis.
  3. Tan MK, Muhammad AA, Gorochov AV, Abdullah NA
    Zootaxa, 2024 Feb 20;5415(1):117-143.
    PMID: 38480212 DOI: 10.11646/zootaxa.5415.1.5
    Recent collection in Panti Forest Reserve in Johor, Peninsular Malaysia offered us the opportunity to better understand the species in southern Malay Peninsula. Two new species and one new genus of Meconematini are described here: Cercoteratura reflexa sp. n. and Platycercotura caricauda gen. et sp. n. We present new locality records for Peracca macritchiensis Tan & Ingrisch, 2014, Viriacca viridis Ingrisch, 1998; Lipotactes (Dialipotactes) maculatus Hebard, 1922; Asiophlugis rete Gorochov, 1998; and Arnobia pilipes tropica Gorochov, 1998, all of which were previously recorded in Pahang (Peninsular Malaysia) and Singapore, suggest that the distribution of these species is continuous between Pahang and Singapore. New locality record for Asiophlugis temasek temasek Gorochov & Tan, 2011, previously known only from Singapore, indicates that this subspecies is no longer endemic to Singapore.
  4. Tan MH, Foo CH, Ohn MH, Ohn KM
    BMJ Case Rep, 2022 Mar 23;15(3).
    PMID: 35321909 DOI: 10.1136/bcr-2021-245360
    Classic Rosai-Dorfman-Destombes disease (RDD) is a rare histiocytic disorder with bilateral massive painless cervical lymphadenopathy. It is a mysterious disease and there is little knowledge of its pathogenesis, clinical features, radiological findings, laboratory investigations, effective treatments and prognosis. Some of its clinical presentations may overlap with those of Mycobacterium tuberculosis infection. Just like tuberculosis infection, RDD may involve many other organs, for example, skin, kidney, bone, brain and spine. The diagnosis can easily be overlooked, especially in communities hyperendemic to tuberculosis infection. We report our experience in diagnosing and managing a patient with spinal RDD with concurrent tuberculosis infection, who was treated empirically for cervical tuberculous lymphadenitis without a conclusive laboratory finding prior to her spinal condition. In view of her acute neurological deficit, emergency spinal decompression was performed. Her intraoperative spinal samples had shown classic histopathological features of RDD. We believe the lymphadenopathy was part of the clinical presentation of RDD. She showed favourable neurological recovery throughout the follow-up.
  5. Mohd Yassin NA, Kamarudin M, Hamdan M, Tan PC
    Am J Obstet Gynecol MFM, 2024 May;6(5):101308.
    PMID: 38336174 DOI: 10.1016/j.ajogmf.2024.101308
    BACKGROUND: The global cesarean delivery rate is high and continues to increase. A bladder catheter is usually placed for the cesarean delivery because a distended bladder is assumed to be at higher risk of injury during surgery and to compromise surgical field exposure. Preliminary data suggest that self bladder emptying (no catheter) at cesarean delivery may have advantages and be safe.

    OBJECTIVE: This study aimed to compare the effects of self bladder emptying and indwelling Foley bladder catheterization for planned cesarean delivery on the rate of postpartum urinary retention and maternal satisfaction.

    STUDY DESIGN: A randomized controlled trial was conducted in a tertiary university hospital from January 10, 2022 to March 22, 2023. A total of 400 participants scheduled for planned cesarean delivery were randomized: 200 each to self bladder emptying or indwelling Foley catheter. The primary outcomes were postpartum urinary retention (overt and covert) and maternal satisfaction with allocated bladder care. Analyses were performed using t test, Mann-Whitney U test, chi-square test, or Fisher exact test, as appropriate. Logistic regression was used to adjust for differences in characteristics.

    RESULTS: Postpartum urinary retention rates were 1 per 200 (0.6%) and 0 per 200 (P>.99) (a solitary case of covert retention) and maternal satisfaction scores (0-10 visual numerical rating scale), expressed as median (interquartile range) were 9 (8-9.75) and 8 (8-9) (P=.003) in the self bladder emptying and indwelling Foley catheter arms, respectively. Regarding secondary outcomes, time to flatus passage, satisfactory ambulation, urination, satisfactory urination, satisfactory breastfeeding, and postcesarean hospital discharge was quickened in the self bladder emptying group. Pain scores at first urination were decreased and no lower urinary tract symptom was more likely to be reported with self bladder emptying. Surgical field view, operative blood loss, duration of surgery, culture-derived urinary tract infection, postvoid residual volume, and pain score at movement were not different. There was no bladder injury.

    CONCLUSION: Self bladder emptying increased maternal satisfaction without adversely affecting postpartum urinary retention. Recovery was enhanced and urinary symptoms were improved. The surgeon was not impeded at operation. No safety concern was found.

  6. Lim AS, Krishnan S, Tan G, Stewart D, Al-Diery T
    Curr Pharm Teach Learn, 2024 Aug;16(8):102097.
    PMID: 38670829 DOI: 10.1016/j.cptl.2024.04.013
    INTRODUCTION: Self-awareness of strengths and weaknesses through self-reflection are important for life-long learning and development. The aim of this study was to assess the alignment in third-year undergraduate pharmacy students' self-reflections of their objective structured clinical exam (OSCE) performance to their actual OSCE scores and explore the most common aspects students reflected on as markers of perceived performance.

    METHODS: Students completed a three-station OSCE and a written self-reflection about their performance. These reflections were coded using a latent pattern content analysis, with categories defined as "doing well (≥ 50% on exam)" and "not doing well (< 50% on exam)" and compared to their actual OSCE exam scores, to determine the degree of alignment.

    RESULTS: Two hundred sixty-nine students completed the OSCE and reflection. Students had a low degree of alignment between their self-reflections and actual OSCE performance. Low alignment was overwhelmingly prevalent and significant in high-achieving students with OSCE scores of ≥90%. Most common aspects students reflected on as indicators of performance were finishing on time and communicating effectively. High-achieving students reflected on aspects such as empathy, systematic questioning, and patient teach-back as aspects of their performance.

    CONCLUSIONS: Student reflections on exam performance do not align with their actual performance, particularly amongst the high-achieving students. High-achieving students were more aware of the different aspects that affected their performance. To ensure that high-achieving students are aware of their strengths, educators should provide more targeted feedback mechanisms and positive reassurances to help these students become more confident in their decision-making skills.

  7. Su Y, Chai XH, Tan CP, Liu YF
    J Food Sci, 2024 Apr 25.
    PMID: 38660921 DOI: 10.1111/1750-3841.17028
    In this paper, the compatibility, phase behavior, and crystallization properties of the binary blends of palm kernel stearin (PKS) and anhydrous milk fat (AMF) were investigated by analyzing the solid fat content (SFC), thermal properties, polymorphism, and microstructure, with the aim of providing theoretical guidance for the blending of oils. The results showed that the PKS content primarily determined the SFC trend of the binary blends. However, the binary blends demonstrated poor miscibility and eutectic behavior was predominantly observed in the system, particularly at higher temperatures. Only α and β' forms appeared in this blended system. Simultaneously, the addition of PKS elevated the liquid phase transition temperature of the binary blends, considerably significantly increased their crystallization rate when the addition of PKS was more than 20% and increased the density and size of the fat crystals. Finally, the mixing design optimization method was used to get the most suitable ratio of the binary blends in the refrigerated cream system with PKS:AMF to be 0.914:0.086. The cream prepared with the above binary blends was indeed superior in overrun and firmness and had high stability. PRACTICAL APPLICATION: Some fats with special advantages are often limited in their wide application because of their poor crystallization ability. In this paper, the crystallization ability of fats is improved, and their application scenarios are increased through the combination of fats, so as to provide reference for the production of special fats for food.
  8. Tan XT, Mohd Shuhairi NB, Mohd Tap R, Amran F
    Indian J Med Microbiol, 2024 Jul 05;50:100663.
    PMID: 38964501 DOI: 10.1016/j.ijmmb.2024.100663
    PURPOSE: Candida albicans is the second most common cause of candidemia in Malaysia. The Clinical and Laboratory Standards Institute (CLSI) broth microdilution method is the gold standard for determining its minimum inhibitory concentration (MIC); however, it is laborious and time-consuming. This study was conducted to evaluate the usefulness of alternative methods, namely Sensititre YeastOne (SYO), VITEK 2 system, and E-test for determining the MIC of clinical C. albicans isolates.

    MATERIALS AND METHODS: The susceptibilities of 95 C. albicans isolates were compared between SYO, VITEK 2 system, and E-test with CLSI broth microdilution method. The categorical agreement (CA), essential agreement (EA), very major errors (VME), major errors (ME) and minor errors (MiE) were calculated.

    RESULTS: Our finding showed the CA varied for SYO from 96.8% to 100%, while the EA ranged from 91.6% to 100%. The SYO method showed 1.1% of VME and ME, and up to 3.2% of MiE. Next, the CA and EA ranges for the VITEK 2 system were 97.8%-100% and 23.2%-100%, respectively. In the VITEK 2 technique, 1.1% of VME were found. For the E-test, the CA varied from 83.2% to 100% while the EA ranged from 64.2% to 98.9%. The E-test method showed 1.1% of VME and up to 16.8% of MiE.

    CONCLUSIONS: In conclusion, SYO and VITEK 2 (except flucytosine) could be potential alternatives to the CLSI broth microdilution method in determining the MIC of C. albicans.

  9. Esmaon R, Lim BK, Gan F, Hamdan M, Tan PC
    BMC Pregnancy Childbirth, 2024 Jul 04;24(1):461.
    PMID: 38965486 DOI: 10.1186/s12884-024-06616-7
    BACKGROUND: Maternal Group B Streptococcus (GBS) colonization is influenced by many factors but results are inconsistent. Consideration of antenatal risk factors may help inform decision making on GBS microbiological culture screening where universal screening is not standard of care. We sought to identify independent predictors of GBS colonization at 34-37 weeks gestation incorporating vaginal symptoms, perineal hygiene measures, sexual activity, and a potential novel factor, constipation.

    METHODS: In this prospective cross-sectional study, 573 women at 34-37 weeks gestation had an ano-vaginal swab taken and sent for selective culture for GBS. Women were asked about vaginal bleeding, discharge, irritation and candidiasis, antibiotic use during pregnancy, ano-vaginal hygiene practices such as douching and perineal cleansing after toileting, sexual intercourse related activities, and a potential novel factor for GBS carriage, constipation. Maternal basic demographics and obstetric-related characteristics were also collected. Bivariate analyses were performed to identify associates of GBS colonization. All variables with p 

  10. Noordiana SH, Tan Hui Fang F, Kamarudin NA, Azman M
    Cureus, 2024 Jun;16(6):e61934.
    PMID: 38978941 DOI: 10.7759/cureus.61934
    Tracheoesophageal puncture (TEP) followed by voice prosthesis placement stands as the primary method for voice rehabilitation after laryngectomy, heralded for its effectiveness. While generally well-tolerated, the procedure does pose potential long-term complications. These include prosthesis valve leakage, scarring, and prosthesis displacement, all of which can impede phonation capabilities. Of these, prosthesis leakage emerges as the most critical concern, precipitated by the progressive widening of the fistula. This complication can precipitate aspiration pneumonitis, stemming from the loss of physical separation between the esophagus and trachea. This case series details three instances where persistent tracheoesophageal fistula arose following TEP, necessitating surgical intervention. Herein, we present the clinical manifestations, surgical approach employing a simple two-layer closure, and ensuing outcomes.
  11. Liao Z, Alrosan M, Alu'datt MH, Tan TC
    J Food Sci, 2024 Jul;89(7):3878-3893.
    PMID: 38865248 DOI: 10.1111/1750-3841.17143
    The popularity of royal jelly (RJ) as a functional food has attracted attention from various industries, especially nutraceuticals, due to the increasing demand from health enthusiasts. Sebacic acid, 10-hydroxy decanoic acid, and trans-10-hydroxy-2-decanoic acid are the primary medium-chain fatty acids (MCFAs) within RJ responsible for their health benefits. This review aims to consolidate information on these MCFAs' metabolic relationship and health functionalities in nutraceutical applications. We also investigated the natural characteristics mediated by these MCFAs and their metabolism in organisms. Finally, the production of these MCFAs using conventional (from castor oil) and alternative (from RJ) pathways was also discussed. This review can be a reference for using them as functional ingredients in nutraceutical industries.
  12. Tariq R, Zolkepli IA, Isawasan P, Tan C, Alhammad MM
    Data Brief, 2024 Aug;55:110758.
    PMID: 39156667 DOI: 10.1016/j.dib.2024.110758
    This paper describes a dataset collected from a survey carried out in the United Kingdom, Malaysia, and Pakistan, to understand the variables that impact political trust. The data was collected from September to November 2021 via an online survey on Google Forms, and 472 valid responses were obtained. Drawing on relevant literature, the survey instrument was designed to cover the respondents' opinions concerning partisanship, social media utilization, online social capital, voluntary online and offline political participation, and political trust. The dataset offers useful insights for institutional practitioners and policymakers working in the domains of democracy and political communication, facilitating policy formulation to bolster political trust through collaborative crowdsourcing.
  13. Chen D, Lee YY, Tan CP, Wang Y, Qiu C
    J Agric Food Chem, 2024 Sep 04;72(35):19480-19493.
    PMID: 39171455 DOI: 10.1021/acs.jafc.4c05495
    Pickering foams have great potential for applications in aerated foods, but their foaming ability and physical stability are still far from satisfactory. Herein, solid lipid particles (SLNs) were fabricated by using diacylglycerol of varying acyl chain lengths with modification by a protein. The SLNs showed different crystal polymorphisms and air-water interfacial activity. C14-DAG SLN with a contact angle ∼ 79° formed aqueous foam with supreme stability and high plasticity. Whey protein isolate and sodium caseinate (0.1 wt %) considerably enhanced the foamability and interfacial activity of SLNs and promoted the packing of particles at the bubble surface. However, high protein concentration caused foam destruction due to the competitive adsorption effect. β-sheet increased in protein after adsorption and changed the polymorphism and thermodynamic properties of SLN. The foam collapsing behaviors varied in the presence of protein. The results gave insights into fabricating ultrastable aqueous foams by using high-melting DAG particles. The obtained foams demonstrated good temperature sensitivity and plasticity, which showed promising application prospects in the food and cosmetic fields.
  14. Chong WK, Ng BJ, Tan LL, Chai SP
    Chem Soc Rev, 2024 Sep 02.
    PMID: 39222069 DOI: 10.1039/d3cs01040f
    Photocatalytic water splitting represents a leading approach to harness the abundant solar energy, producing hydrogen as a clean and sustainable energy carrier. Zinc indium sulfide (ZIS) emerges as one of the most captivating candidates attributed to its unique physicochemical and photophysical properties, attracting much interest and holding significant promise in this domain. To develop a highly efficient ZIS-based photocatalytic system for green energy production, it is paramount to comprehensively understand the strengths and limitations of ZIS, particularly within the framework of solar-driven water splitting. This review elucidates the three sequential steps that govern the overall efficiency of ZIS with a sharp focus on the mechanisms and inherent drawbacks associated with each phase, including commonly overlooked aspects such as the jeopardising photocorrosion issue, the neglected oxidative counter surface reaction kinetics in overall water splitting, the sluggish photocarrier dynamics and the undesired side redox reactions. Multifarious material design strategies are discussed to specifically mitigate the formidable limitations and bottleneck issues. This review concludes with the current state of ZIS-based photocatalytic water splitting systems, followed by personal perspectives aimed at elevating the field to practical consideration for future endeavours towards sustainable hydrogen production through solar-driven water splitting.
  15. Mei Y, Hu H, Deng L, Sun X, Tan W
    Sci Rep, 2022 Jul 27;12(1):12857.
    PMID: 35896572 DOI: 10.1038/s41598-022-16119-0
    Isosteviol sodium (STVNa) is a beyerane diterpene synthesized via acid hydrolysis of stevioside, which can improve glucose and lipid metabolism in animals with diabetes. However, it remains unknown whether STVNa can exhibit a therapeutic effect on nonalcoholic fatty liver disease (NAFLD) and its underlying mechanism. We hypothesize that autophagic initiation may play a key role in mediating the development of NAFLD. Herein, we assessed the effects of STVNa on NAFLD and its underlying mechanisms. The results demonstrated that STVNa treatment effectively ameliorated NAFLD in rats fed high-fat diet (HFD). Moreover, STVNa decreased the expression of inflammation-related genes and maintained a balance of pro-inflammatory cytokines in NAFLD rats. STVNa also reduced lipid accumulation in free fatty acid (FFA)-exposed LO2 cells. In addition, STVNa attenuated hepatic oxidative stress and fibrosis in NAFLD rats. Furthermore, STVNa enhanced autophagy and activated Sirtuin 1/adenosine monophosphate-activated protein kinase (Sirt1/AMPK) pathway both in vivo and in vitro, thus attenuating intracellular lipid accumulation. In summary, STVNa could improve lipid metabolism in NAFLD by initiating autophagy via Sirt1/AMPK pathway. Therefore, STVNa may be an alternative therapeutic agent for treatment of NAFLD.
  16. Zetian D, Juan X, Jiaxin D, Hoe Tan W
    Front Psychol, 2024;15:1374649.
    PMID: 39246312 DOI: 10.3389/fpsyg.2024.1374649
    The integrity and clarity of information have long been regarded as the cornerstones of advertising strategy. However, recent game advertising has taken a different approach. Specifically, incomplete game videos, especially those showcasing losing gameplay, are more likely to stimulate players' interest compared to complete videos of winning gameplay. This study, through five experiments, uncovers a dual-pathway mechanism behind this phenomenon. Firstly, information gaps resulting from incomplete videos trigger curiosity drive, compelling viewers to seek more information and reinforcing their willingness to engage in gaming. Secondly, witnessing failures in game demonstrations activates components of downward social comparison and competitive motivation. These findings offer valuable insights into the complex dynamics of game advertising, shedding light on the effects of information gaps, curiosity, and social comparison. They provide valuable implications for advertising strategies within the gaming industry.
  17. Hor JW, Toh TS, Lim SY, Tan AH
    J Parkinsons Dis, 2024 Aug 23.
    PMID: 39213091 DOI: 10.3233/JPD-240172
    There is increasing evidence that microbial-based therapies can be useful in people with Parkinson's disease (PD). In this viewpoint, we provide a state-of-the-art review of the clinical and pre-clinical evidence for probiotics and prebiotics in PD. Currently, short-term clinical studies, including double-blind placebo-controlled randomized clinical trials, have demonstrated safety, and efficacy primarily in improving constipation-related symptoms. Pre-clinical studies consistently reported improvements in a range of biological markers and outcomes, including evidence for attenuation of gut dysfunction and neuroprotection. Bacteria from the genus Lactobacillus and Bifidobacterium have been the most frequently studied both in clinical and pre-clinical probiotics studies, while research into prebiotics is still limited and primarily involved resistant starch and fructooligosaccharides. We provide practical suggestions for clinicians on how to advise patients in the clinic regarding these popular treatments, and important caveats to be aware of. Finally, areas for further advancements are highlighted. It is envisaged that in the future, microbial-based therapies may benefit from personalization based on an enhanced understanding of a whole range of host factors and host-microbiome interactions.
  18. Tan BH, Ahemad N, Pan Y, Ong CE
    Xenobiotica, 2024 Aug 28.
    PMID: 39175333 DOI: 10.1080/00498254.2024.2395557
    Cytochrome P40 (CYP) enzymes dominate the metabolism of numerous endogenous and xenobiotic substances. While it is commonly believed that CYP-catalysed reactions result in the detoxication of foreign substances, these reactions can also yield reactive intermediates that can bind to cellular macromolecules to cause cytotoxicity or irreversibly inactivate CYPs that create them.Mechanism-based inactivation (MBI) produces either irreversible or quasi-irreversible inactivation and is commonly caused by CYP metabolic bioactivation to an electrophilic reactive intermediate. Many drugs that have been known to cause MBI in CYPs have been discovered as perpetrators in drug-drug interactions throughout the last 20-30 years.This review will highlight the key findings from the recent literature about the mechanisms of CYP enzyme inhibition, with a focus on the broad mechanistic elements of MBI for widely used drugs linked to the phenomenon. There will also be a brief discussion of the clinical or pharmacokinetic consequences of CYP inactivation with regard to drug interaction and toxicity risk.Gaining knowledge about the selective inactivation of CYPs by common therapeutic drugs helps with the assessment of factors that affect the systemic clearance of co-administered drugs and improves comprehension of anticipated interactions with other drugs or xenobiotics.
  19. Syed Ali SA, Ilankoon IMSK, Zhang L, Tan J
    J Hazard Mater, 2024 Aug 17;479:135554.
    PMID: 39232354 DOI: 10.1016/j.jhazmat.2024.135554
    Achieving circularity in the plastic economy predominantly depends on sourcing higher quality recyclates. Packaging plastic poses a significant challenge as it is often not prioritised for collection or recycling initiatives. The presence of additives, such as printing ink, impedes the quality of recyclates. Considering the volume of packaging plastics and the importance of branding (aesthetics and consumer information), ink removal is a critical pre-treatment step. However, the literature is limited, with only 14 studies exploring de-inking processes. Drawing parallels with the detergent laundering process, surfactants have been widely investigated in plastic de-inking, with cationic surfactants proving the most effective with a de-inking efficiency of up to 100%. However, concerns exist regarding the toxic and hazardous nature of the surfactants and chemicals. The average hazard quotient (AHQ) was developed, which compares de-inking chemicals as one of the key findings. AHQ provides a quantitative proxy for the hazards and toxicities, which are qualitatively presented as part of the globally harmonised system (GHS) classification of chemicals. To drive emerging packaging plastic de-inking, including the development of green surfactants (e.g. gamma-valerolactone), this work enables an informed chemical selection minimising potential hazards (rather than creating more adverse effects in plastic recycling processes) and toxicities from plastic waste, fulfilling the objectives of cleaner plastic waste recycling.
  20. Hoang T, Kieu H, Nguyen V, Tran T, Ngee T, Duong H
    PMID: 39230213
    BACKGROUND: To evaluate the treatment outcomes of lateral interbody bone graft surgery and posterior percutaneous screws for lumbar spinal stenosis Methods: This is a cross-sectional descriptive study. There were 27 patients with 30 segments of surgery diagnosed with lumbar spinal stenosis that were surgically treated with the XLIF method. Clinical outcomes measured included VAS scores for lower back pain and leg pain, ODI, and JOA scores. Magnetic resonance imaging of the lumbar spine after surgery was used to evaluate indirect decompression. X-ray or CT scan to evaluate bone fusion after 6 months of surgery. Differences were determined by independent T-test.

    RESULTS: There were 27 patients with 30 segments of surgery. They were 12 males and 15 females with an average age of 58.81±8.1. There was significant improvement in VAS for lower back pain from 7.11±1.31 to 3.67±1.3, VAS for leg pain from 6.81±2.19 to 1.59±1.89, ODI from 26.41±8.95 to 13.69±8.34, and JOA score from 7.63±2.87 to 13.5±1.73. A-P diameter increased 134%, lateral diameter increased 120%, lateral recess depth increased 166%, disc height increased 126%, foraminal height increased 124%, spinal canal area increased 30%. The p-values were all <0.001. The average hospital stay was 6.79±3.01 days. Complications included 1 pedicle screw malformation, 1 ALL avulsion fracture, 1 abdominal herniation, 1 venous damage, 1 failure.

    CONCLUSION: XLIF surgery presents a favorable option for patients with lumbar spinal stenosis. This is a minimally invasive surgical method that reduces pain, reduces bleeding, and is effective in indirectly decompressing the spinal canal both clinal and imaging.

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