Displaying publications 41 - 60 of 224 in total

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  1. Salimi E, Ghaee A, Ismail AF, Karimi M
    Int J Biol Macromol, 2018 Sep;116:364-377.
    PMID: 29709537 DOI: 10.1016/j.ijbiomac.2018.04.137
    The main aim of this study was to evaluate the suitability of sulfonated alginate as a modifying agent to enhance the hemocompatibility of self-fabricated polyethersulfone (PES) hollow fiber membrane for blood detoxification. Sodium alginate was sulfonated with a degree of 0.6 and immobilized on the membrane via surface amination and using glutaraldehyde as cross-linking agent. Coating layer not only improved the membrane surface hydrophilicity, but also induced -39.2 mV negative charges on the surface. Water permeability of the modified membrane was enhanced from 67 to 95 L/m2·h·bar and flux recovery ratio increased more than 2-fold. Furthermore, the modified membrane presented higher platelet adhesion resistance (reduced by more than 90%) and prolonged coagulation time (35 s for APTT and 14 s for PT) in comparison with the pristine PES hollow fiber membrane, which verified the improved anti-thrombogenicity of the modified membrane. On the other hand, obtained membrane after 3 h coating could remove up-to 60% of the uremic toxins. According to the obtained data, sulfonated alginate can be a promising modifying agent for the future blood-contacting membrane and specially blood purification issues.
  2. Ahmad S, Ismail AI, Zim MAM, Ismail NE
    Front Public Health, 2019;7:420.
    PMID: 32039131 DOI: 10.3389/fpubh.2019.00420
    Purpose: The elusive goal of asthma management guidelines is to achieve and maintain good asthma control in asthmatic patients. Against a background of long-term respiratory limitations when living with asthma, stigma and low self-esteem have also been identified as the social phenomenon among adult asthmatics. This study aimed to assess the levels of self-stigma, self-esteem, and asthma control, and to investigate the impact of self-stigma and self-esteem as psychosocial factors on asthma control in Malaysian adults living with asthma.
    Materials and Methods: In this multicenter cross-sectional study, post-ethics approval and patients' consents, 152 stable asthmatic patients (aged > 18 years old; nil cognitive disability; not diagnosed with other respiratory diseases) were recruited from four respiratory clinics in Selangor, Malaysia. The patients' socio-demographic, medical, and psychosocial (self-stigma and self-esteem) data were recorded in a pre-validated, self-designed questionnaire. All data were analyzed descriptively and inferentially (independent t-test/one-way ANOVA, and multiple linear regression) using the Statistical Package for Social Sciences (SPSS®).
    Results: The enrolled patients showed moderate levels of self-stigma (62.12 ± 6.44) and self-esteem (29.31 ± 3.29), and not well-controlled asthma (17.58 ± 3.99). The number of patients' visits to emergency rooms because of asthma [CI (-1.199, 0.317), p < 0.001] was the significant predictor to asthma control among all selected study variables from socio-demographic and medical data. Moreover, from psychosocial factors both self-stigma [CI (-0.367, 0.190), p < 0.001], and self-esteem [CI (-0.007, 0.033), p = 0.041] found to be the significant predictors of asthma control.
    Conclusion: The preliminary evidences presented in this study found that frequent emergency room visits, high self-stigma and low self-esteem in asthma patients becomes more apparent with poor asthma control. Educational interventions to reduce patients' self-stigma and improve self-esteem are needed to achieve optimal control of asthma.
    Study site: Four respiratory clinics in Selangor, Malaysia (UiTM Respiratory specialist Clinic, Hospital Selayang and Hospital Sungai Buloh)
  3. Mubarak AI, Wan Mohd Shukri WNA, Ismail AK
    Int Marit Health, 2021 7 3;72(2):93-98.
    PMID: 34212348 DOI: 10.5603/IMH.2021.0017
    BACKGROUND: Jellyfish stings are one of the commonest causes of marine animal related injuries in human. Despite mostly being harmless, box jellyfish species can cause major stings with fatalities or systemic envenoming symptoms. There are 15-20 species identified to be life-threatening. There are few reported cases that suggest the presence of deadly box jellyfish in the Malaysian coast. However, numbers of stings around Malaysia are still under reported.

    MATERIALS AND METHODS: This observational study was conducted in Manjung, Perak and Langkawi Island to look at the pattern and incidence of jellyfish stings which occur within 1 year.

    RESULTS: There were 45 sting incidents reported with the highest number of cases occurred in December and February. Cases mainly involved young adults aged 10 to 29 years old. The most common clinical symptom that presented was sudden and persistent pain. Vinegar was applied as first aid in 53.3% of reported stings. All patients were treated symptomatically and discharged well. Stings occurred at mean sea surface temperature of 29.38°C and the wind speed of 7.6 knots. All cases were mild and did not require antivenom.

    CONCLUSIONS: The study showed that the occurrence of jellyfish stings are affected by weather conditions. Jellyfish stings occur seasonally, thus making it predictable and easily preventable with public awareness, early first aid application and use of jellyfish nets.

  4. Saleem H, Zaidi SJ, Ismail AF, Goh PS
    Chemosphere, 2022 Jan;287(Pt 2):132083.
    PMID: 34488054 DOI: 10.1016/j.chemosphere.2021.132083
    One of the most favorable environmental applications of nanotechnology has been in air pollution remediation in which different nanomaterials are used as nanoadsorbents, nanocatalysts, nanofilters, and nanosensors. The nanomaterials have the ability to adsorb several contaminants existing in the air. Also, certain semiconducting nanomaterials materials can be used for photocatalytic remediation. Air contamination control can also be achieved by nanostructured membranes with pores sufficiently small to separate various pollutants from the exhaust. Nanomaterial enabled sensors are also used for the detection of harmful gases such as hydrogen sulfide, sulphur dioxide, and nitrogen dioxide. Conversely, because of the uncertainties in addition to irregularities in size, shape as well as chemical compositions, the existence of some nanomaterials might cause harmful effects on the environment along with the health of people. Thus, concerns were expressed about the transport and conversion of nanoparticles discharged into the surroundings. This review critically examined and assessed the present literature on the application of nanomaterials in the air, together with its negative impacts. The main focus is placed on the application of carbon-based and metal-based nanomaterials for air pollution remediation. It is noted that these nanomaterials demonstrating fascinating properties for improving the environmental pollution remediation system.
  5. Hanapiah M, Zulkifli SZ, Mustafa M, Mohamat-Yusuff F, Ismail A
    Mar Pollut Bull, 2018 Feb;127:453-457.
    PMID: 29475685 DOI: 10.1016/j.marpolbul.2017.12.015
    Diuron is an alternative biocide suggested to replace organotin in formulating antifouling paints to be applied on water-going vessels hull. However, it is potentially harmful to various non-targeted marine organisms due to its toxic properties. Present study aimed to isolate, screen and identify the potential of Diuron-degrading bacteria collected from the marine sediments of Port Klang, Malaysia. Preliminary screening was conducted by exposing isolated bacteria to 430ng/L (background level), followed by 600ng/L and 1000ng/L of Diuron concentrations. Nine bacteria colonies survived the exposure of the above concentrations. However, only two strains can tolerate to survive up to 1000μg/L, which were then characterised and identified using phenotypic tests and the standard 16S rRNA molecular identification. The strains were identified as Comamonas jiangduensis SZZ 10 and Bacillus aerius SZZ 19 (GenBank accession numbers: KU942479 and KU942480, respectively). Both strains have the potential of Diuron biodegradation for future use.
  6. Udechukwu BE, Ismail A, Zulkifli SZ, Omar H
    Environ Sci Pollut Res Int, 2015 Mar;22(6):4242-55.
    PMID: 25292304 DOI: 10.1007/s11356-014-3663-4
    Sungai Puloh mangrove estuary supports a large diversity of macrobenthic organisms and provides social benefits to the local community. Recently, it became a major recipient of heavy metals originating from industries in the hinterland as a result of industrialization and urbanization. This study was conducted to evaluate mobility and pollution status of heavy metals (Cd, Cu, Ni, Pb, Zn, and Fe) in intertidal surface sediments of this area. Surface sediment samples were collected based on four different anthropogenic sources. Metals concentrations were analyzed using an atomic absorption spectrophotometer (AAS). Results revealed that the mean concentrations were Zn (1023.68 ± 762.93 μg/g), Pb (78.8 ± 49.61 μg/g), Cu (46.89 ± 43.79 μg/g), Ni (35.54 ± 10.75 μg/g), Cd (0.94 ± 0.29 μg/g), and Fe (7.14 ± 0.94%). Most of the mean values of analyzed metals were below both the interim sediment quality guidelines (ISQG-low and ISQG-high), except for Pb concentration (above ISQG-low) and Zn concentration (above ISQG-high), thus suggesting that Pb and Zn may pose some environmental concern. Cadmium, Pb, and Zn concentrations were above the threshold effect level (TEL), indicating seldom adverse effect of these metals on macrobenthic organisms. Pollution load index (PLI) indicated deterioration and other indices revealed the intertidal surface sediment is moderately polluted with Cd, Pb, and Zn. Therefore, this mangrove area requires urgent attention to mitigate further contamination. Finally, this study will contribute to data sources for Malaysia in establishing her own ISQG since it is a baseline study with detailed contamination assessment indices for surface sediment of intertidal mangrove area.
  7. Dantham P, Nuvvula S, Ismail AF, Akkilagunta S, Mallineni SK
    Dent Med Probl, 2024;61(2):209-216.
    PMID: 38668708 DOI: 10.17219/dmp/156655
    BACKGROUND: Several risk factors contribute to the development of dental caries in children, including sociodemographic, dietary, oral hygiene-related and other miscellaneous factors. Maternal smoking was highly associated with dental caries when compared to smoking by fathers or other household members.

    OBJECTIVES: The aim of the study was to determine the prevalence of dental caries and their association with exposure to environmental tobacco smoke (ETS) among 5- to 10-year-old students attending private and government schools.

    MATERIAL AND METHODS: A cross-sectional analytical study was conducted among schoolchildren. Data was collected from the primary caregivers using a pre-tested form to assess the ETS exposure under 5 domains based on history: antenatal exposure; exposure during the index period; exposure in the school neighborhood; exposure in restaurants/roadside stalls; and exposure in bus stops/railway stations. Dental caries was assessed based on the World Health Organization (WHO) guidelines from 1997. The association was reported using prevalence ratios (PRs) (95% confidence interval (CI)).

    RESULTS: Data was obtained from 211 schoolchildren attending government (39.8%) and private schools (60.2%). The overall prevalence (95% CI) of dental caries was 49.3% (42.5-56.1%). Among all the risk factors evaluated in the study, exposure to ETS was associated with a significantly increased risk of dental caries. The adjusted prevalence ratio (APR) of ETS exposure varied with the mother's educational status and high sugar exposure, although this was statistically insignificant.

    CONCLUSIONS: The prevalence of dental caries among schoolchildren aged 5 to 10 years in the city was moderate and similar to the national average. Among the risk factors assessed in the study, antenatal exposure to ETS was found to significantly increase the prevalence of dental caries by 41% after adjusting for other factors. Therefore, it is important to educate parents on the causal role of ETS exposure in dental caries.

  8. Subramaniam MN, Goh PS, Lau WJ, Ismail AF
    Nanomaterials (Basel), 2019 Apr 17;9(4).
    PMID: 30999639 DOI: 10.3390/nano9040625
    Heavy metal (HM) pollution in waterways is a serious threat towards global water security, as high dosages of HM poisoning can significantly harm all living organisms. Researchers have developed promising methods to isolate, separate, or reduce these HMs from water bodies to overcome this. This includes techniques, such as adsorption, photocatalysis, and membrane removal. Nanomaterials play an integral role in all of these remediation techniques. Nanomaterials of different shapes have been atomically designed via various synthesis techniques, such as hydrothermal, wet chemical synthesis, and so on to develop unique nanomaterials with exceptional properties, including high surface area and porosity, modified surface charge, increment in active sites, enhanced photocatalytic efficiency, and improved HM removal selectivity. In this work, a comprehensive review on the role that nanomaterials play in removing HM from waterways. The unique characteristics of the nanomaterials, synthesis technique, and removal principles are presented. A detailed visualisation of HM removal performances and the mechanisms behind this improvement is also detailed. Finally, the future directions for the development of nanomaterials are highlighted.
  9. Ramli NA, Iberahim S, Che Ismail AA, Hussin H
    Caspian J Intern Med, 2023;14(2):237-248.
    PMID: 37223288 DOI: 10.22088/cjim.14.2.237
    BACKGROUND: Cancer-related anaemia is one of the main burdens in oncology, although the available data on its prevalence and treatment options such as blood transfusion are often contradictory. This study aimed to evaluate the prevalence of anaemia and the requirement for packed red blood cell (PRBC) transfusion among women with breast cancer (BC) and to determine the associated factors for chemotherapy-induced anaemia (CIA).

    METHODS: This cross-sectional retrospective study conducted in Kelantan involved 104 newly diagnosed female BC patients from 2015 to 2016 who underwent chemotherapy. For statistical analysis, chi-square was used to compare between CIA and non-CIA groups. In addition, simple and multiple logistic regression were used to determine the association of the CIA.

    RESULTS: Our study revealed that 34.6% (n=36) of patients had mild anaemia, and 59.6% (n=62) had normal haemoglobin at pre-chemotherapy. The prevalence of anaemia increased from 40.4% to 77% at the end of our study. About 30.8% of patients received PRBC transfusion during chemotherapy with mean haemoglobin before the first transfusion of 7.9 g/dl. CIA was observed in 54.8% of cases. There was no significant association between CIA concerning the patient characteristic, cancer characteristic, or cancer treatment.

    CONCLUSION: We concluded that a significant proportion (40.4%) of BC patients was anaemic even before chemotherapy, with the red blood cell requirements up to 30.8% throughout chemotherapy. A larger prospective study is needed to determine the predictors for the CIA and subsequently improve patient management.

  10. Ismail AZ, Gunasekharan M, Karunakaran T, Mohd Faudzi SM
    Acta Crystallogr E Crystallogr Commun, 2023 Mar 01;79(Pt 4):287-291.
    PMID: 37057012 DOI: 10.1107/S2056989023001925
    High-quality single crystals of the title compound, 2C13H11NO2·H2O, were grown and a structural analysis was performed. The asymmetric unit comprises one mol-ecule of 3-(3-hy-droxy-phen-yl)-1-(1H-pyrrol-2-yl)prop-2-en-1-one (3HPPP), which was recently discovered to be a promising anti-MRSA candidate, and a half-mol-ecule of water. The compound crystallizes in the monoclinic space group P2/c. The crystal structure features inter-molecular pyrrole-N-H⋯O (water), carbon-yl/keto-C-O⋯H-O-phenol and phenol-C-O⋯H (water) hydrogen bonds, which help to consolidate the crystal packing. A Hirshfeld surface analysis for the components in the asymmetric unit showed that H⋯H (40.9%) and H⋯C/C⋯H (32.4%) contacts make the largest contributions to the inter-molecular inter-actions of 3HPPP. Considering the presence of water, in its vicinity H⋯O/O⋯H and H⋯C/C⋯H are the most significant contacts, contributing 48.7 and 29.8%, respectively.
  11. Rahman F, Ismail A, Omar H, Hussin MZ
    Toxicol Rep, 2017;4:502-506.
    PMID: 28959680 DOI: 10.1016/j.toxrep.2017.09.003
    The Milky stork is listed as an endangered species endemic to the Southeast Asia region. In Malaysia, the population is currently being reintroduced back into the wild. However, the increase of anthropogenic activity throughout the coastal area might expose the population to hazardous chemicals such as heavy metals. This study highlights the contamination of cadmium (Cd) and lead (Pb) in the Milky stork's diet. Additionally, this is the first time an integrated exposure model being used to assess heavy metal exposure risk to the population. Lead level (5.5-7.98 mg kg-1) in particular was relatively high compared to Cd (0.08-0.33 mg kg-1). This was probably related to the different niches occupied by the species in the aquatic environment. The results further show that the predicted exposure doses (through intake of both food and water) for all metals are much lower than the Tolerable Daily Intake (TDI) values. The total exposure dose for Cd was 0.11 mg kg-1 d-1 with TDI value of 0.54 mg kg-1 d-1 while Pb total exposure dose was 0.31 mg kg-1 d-1 with TDI value of 0.64 mg kg-1 d-1. Several possible factors that could lead to the observed pattern were discussed. In conclusion, there is an urgent need to improve the current habitat quality to protect the endangered species. The authors also emphasized on the protection of remaining Milky stork's habitats i.e. mudflats and mangroves and the creation of buffer zone to mitigate the negative impacts that may arise from pollution activity.
  12. Suresh D, Goh PS, Ismail AF, Hilal N
    Membranes (Basel), 2021 Oct 28;11(11).
    PMID: 34832061 DOI: 10.3390/membranes11110832
    Surface modification of membranes is an effective approach for imparting unique characteristics and additional functionalities to the membranes. Chemical grafting is a commonly used membrane modification technique due to its versatility in tailoring and optimizing the membrane surface with desired functionalities. Various types of polymers can be precisely grafted onto the membrane surface and the operating conditions of grafting can be tailored to further fine-tune the membrane surface properties. This review focuses on the recent strategies in improving the surface design of liquid separation membranes through grafting-from technique, also known as graft polymerization, to improve membrane performance in wastewater treatment and desalination applications. An overview on membrane technology processes such as pressure-driven and osmotically driven membrane processes are first briefly presented. Grafting-from surface chemical modification approaches including chemical initiated, plasma initiated and UV initiated approaches are discussed in terms of their features, advantages and limitations. The innovations in membrane surface modification techniques based on grafting-from techniques are comprehensively reviewed followed by some highlights on the current challenges in this field. It is concluded that grafting-from is a versatile and effective technique to introduce various functional groups to enhance the surface properties and separation performances of liquid separation membranes.
  13. Nasruddin NS, Azmai MN, Ismail A, Saad MZ, Daud HM, Zulkifli SZ
    ScientificWorldJournal, 2014;2014:312670.
    PMID: 25587561 DOI: 10.1155/2014/312670
    This study was conducted to record the histological features of the gastrointestinal tract of wild Indonesian shortfin eel, Anguilla bicolor bicolor (McClelland, 1844), captured in Peninsular Malaysia. The gastrointestinal tract was segmented into the oesophagus, stomach, and intestine. Then, the oesophagus was divided into five (first to fifth), the stomach into two (cardiac and pyloric), and the intestine into four segments (anterior, intermediate, posterior, and rectum) for histological examinations. The stomach had significantly taller villi and thicker inner circular muscles compared to the intestine and oesophagus. The lamina propria was thickest in stomach, significantly when compared with oesophagus, but not with the intestine. However, the intestine showed significantly thicker outer longitudinal muscle while gastric glands were observed only in the stomach. The histological features were closely associated with the functions of the different segments of the gastrointestinal tract. In conclusion, the histological features of the gastrointestinal tract of A. b. bicolor are consistent with the feeding habit of a carnivorous fish.
  14. Halim I, Arep H, Kamat SR, Abdullah R, Omar AR, Ismail AR
    Saf Health Work, 2014 Jun;5(2):97-105.
    PMID: 25180141 DOI: 10.1016/j.shaw.2014.04.002
    BACKGROUND: Prolonged standing has been hypothesized as a vital contributor to discomfort and muscle fatigue in the workplace. The objective of this study was to develop a decision support system that could provide systematic analysis and solutions to minimize the discomfort and muscle fatigue associated with prolonged standing.

    METHODS: The integration of object-oriented programming and a Model Oriented Simultaneous Engineering System were used to design the architecture of the decision support system.

    RESULTS: Validation of the decision support system was carried out in two manufacturing companies. The validation process showed that the decision support system produced reliable results.

    CONCLUSION: The decision support system is a reliable advisory tool for providing analysis and solutions to problems related to the discomfort and muscle fatigue associated with prolonged standing. Further testing of the decision support system is suggested before it is used commercially.

  15. Ismail AK, Weinstein SA, Auliya M, Sabardin DM, Herbosa TJ, Saiboon IM, et al.
    Clin Toxicol (Phila), 2010 Mar;48(3):222-6.
    PMID: 20345298 DOI: 10.3109/15563650903550964
    The Twin-Barred Tree Snake, Chrysopelea pelias, is a colubrine that, like other members of the genus Chrysopelea, is able to glide in the arboreal strata. Little is known about the effects of its bite. This report is the first clinically documented bite by this relatively uncommon rear-fanged species.
  16. Agusa T, Kunito T, Yasunaga G, Iwata H, Subramanian A, Ismail A, et al.
    Mar Pollut Bull, 2005;51(8-12):896-911.
    PMID: 16023148
    Concentrations of trace elements (V, Cr, Mn, Co, Cu, Zn, Ga, Se, Rb, Sr, Mo, Ag, Cd, Sn, Sb, Cs, Ba, Hg, Tl, Pb and Bi) were determined in muscle and liver of 12 species of marine fish collected from coastal areas in Malaysia. Levels of V, Cr, Mn, Co, Cu, Zn, Ga, Sr, Mo, Ag, Cd, Sn, Ba and Pb in liver were higher than those in muscle, whereas Rb and Cs concentrations showed the opposite trend. Positive correlations between concentrations in liver and muscle were observed for all the trace elements except Cu and Sn. Copper, Zn, Se, Ag, Cd, Cs and Hg concentrations in bigeye scads from the east coast of the Peninsular Malaysia were higher than those from the west, whereas V showed the opposite trend. The high concentration of V in the west coast might indicate oil contamination in the Strait of Malacca. To evaluate the health risk to Malaysian population through consumption of fish, intake rates of trace elements were estimated on the basis of the concentrations of trace elements in muscle of fish and daily fish consumption. Some specimens of the marine fish had Hg levels higher than the guideline value by US Environmental Protection Agency (EPA), indicating that consumption of these fish at the present rate may be hazardous to Malaysian people. To our knowledge, this is the first study on multielemental accumulation in marine fish from the Malaysian coast.
  17. Abubakar A, Mustafa MB, Johari WLW, Zulkifli SZ, Ismail A, Mohamat-Yusuff FB
    Mar Pollut Bull, 2015 Dec 15;101(1):280-283.
    PMID: 26434791 DOI: 10.1016/j.marpolbul.2015.09.041
    A possible tributyltin (TBT)-degrading bacterium isolated from contaminated surface sediment was successfully identified as Klebsiella sp. FIRD 2. It was found to be the best isolate capable of resisting TBT at a concentration of 1000 μg L(-1). This was a concentration above the reported contaminated level at the sampling station, 790 μg L(-1). Further studies revealed that the isolate was Gram negative and resisted TBT concentrations of up to 1500 μg L(-1) in a Minimal Salt Broth without the addition of any carbon source within the first 48 h of incubation. It is expected that additional work could be conducted to check the degradation activity of this new isolate and possibly improve the degradation capacity in order to contribute to finding a safe and sustainable remediation solution of TBT contamination.
  18. Sukadarin EH, Deros BM, Ghani JA, Mohd Nawi NS, Ismail AR
    Int J Occup Saf Ergon, 2016 Sep;22(3):389-98.
    PMID: 27173135 DOI: 10.1080/10803548.2016.1156924
    INTRODUCTION: This review describes standardized ergonomics assessment based on pen-and-paper observational methods for assessing ergonomics risk factors.

    OBJECTIVE: The three main objectives are to analyze published pen-and-paper observational methods, to extract and understand the risk levels of each method and to identify their associated health effects.

    METHODOLOGY: The authors searched scientific databases and the Internet for materials from 1970 to 2013 using the following keywords: ergo, posture, method, observational, postural angle, health effects, pain and diseases. Postural assessments of upper arms, lower arms, wrists, neck, back and legs in six pen-and-paper-based observational methods are highlighted, extracted in groups and linked with associated adverse health effects.

    RESULTS: The literature reviewed showed strengths and limitations of published pen-and-paper-based observational methods in determining the work activities, risk levels and related postural angles to adverse health effects. This provided a better understanding of unsafe work postures and how to improve these postures.

    CONCLUSION: Many pen-and-paper-based observational methods have been developed. However, there are still many limitations of these methods. There is, therefore, a need to develop a new pen-and-paper-based observational method for assessing postural problems.

  19. Zainudin LD, Abdul Hafidz MI, Zakaria AF, Mohd Zim MA, Ismail AI, Abdul Rani MF
    Respirol Case Rep, 2016 Mar;4(1):19-21.
    PMID: 26839696 DOI: 10.1002/rcr2.143
    We report a case of a 34-year-old lady with past history of asthma and pulmonary tuberculosis, who presented 5 weeks pregnant with acute dyspnea. Her chest X-ray showed left-sided complete lung collapse and concomitant right-sided pneumothorax. The pneumothorax was initially managed conservatively with a chest tube but due to its persistence despite suction, was subsequently changed to a Pneumostat(TM), with which she was later discharged. She had a normal echocardiography (ejection fraction [EF] 67%) at 5 weeks of gestation but developed pulmonary hypertension (EF 55%, pulmonary arterial pressure 40.7 mmHg) as the pregnancy progressed. She delivered a healthy baby at 35 weeks via elective lower section caesarean section with spinal anesthesia. We followed her up postnatally and noted the presence of left-sided pulmonary embolism, hypoplastic left lung, and left pulmonary artery. The management of this complex case involved a multidisciplinary effort between general medical, respiratory, obstetric, and cardiothoracic teams.
  20. Chang HC, Sun T, Sultana N, Lim MM, Khan TH, Ismail AF
    Mater Sci Eng C Mater Biol Appl, 2016 Apr 1;61:396-410.
    PMID: 26838866 DOI: 10.1016/j.msec.2015.12.074
    In the current study, electrospinning technique was used to fabricate composite membranes by blending of a synthetic polymer, polylactic acid (PLA) and a natural polymer, poly(3-hydroxybutyrate-co-3-hydroxyvalerate), PHBV. Conductive membranes were prepared by dipping PLA/PHBV electrospun membranes into poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (
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